KEGG 04014 Ras signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04014 Ras signaling pathway 87
hsa04010 MAPK signaling pathway 52
hsa04015 Rap1 signaling pathway 49
hsa04151 PI3K-Akt signaling pathway 49
hsa05200 Pathways in cancer 45
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04014 Ras signaling pathway 105
mmu05200 Pathways in cancer 69
mmu04010 MAPK signaling pathway 69
mmu04015 Rap1 signaling pathway 66
mmu04151 PI3K-Akt signaling pathway 60
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04014 Ras signaling pathway 107
rno04010 MAPK signaling pathway 63
rno05200 Pathways in cancer 62
rno04015 Rap1 signaling pathway 54
rno04151 PI3K-Akt signaling pathway 54
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04014 Ras signaling pathway 90
mcc05200 Pathways in cancer 53
mcc04015 Rap1 signaling pathway 51
mcc04010 MAPK signaling pathway 50
mcc04151 PI3K-Akt signaling pathway 49
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04014 Ras signaling pathway 78
cfa04010 MAPK signaling pathway 47
cfa05200 Pathways in cancer 45
cfa04015 Rap1 signaling pathway 44
cfa04151 PI3K-Akt signaling pathway 37
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04014 Ras signaling pathway 84
fca05200 Pathways in cancer 53
fca04010 MAPK signaling pathway 49
fca04015 Rap1 signaling pathway 49
fca04151 PI3K-Akt signaling pathway 47
Gene list in the network
Symbol Function*
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AKT2 AKT serine/threonine kinase 2
ALDH3B2 aldehyde dehydrogenase 3 family member B2
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
RHOA ras homolog family member A
BDNF brain derived neurotrophic factor
FMNL1 formin like 1
CALM1 calmodulin 1
CALM2 calmodulin 2
CALML3 calmodulin like 3
CAPZB capping actin protein of muscle Z-line subunit beta
CDC42 cell division cycle 42
CDH5 cadherin 5
COL6A3 collagen type VI alpha 3 chain
CSF1R colony stimulating factor 1 receptor
DCN decorin
EFNA1 ephrin A1
EFNA2 ephrin A2
EFNA3 ephrin A3
EFNA4 ephrin A4
EPHA2 EPH receptor A2
ETS2 ETS proto-oncogene 2, transcription factor
FGF2 fibroblast growth factor 2
FGF5 fibroblast growth factor 5
FGF7 fibroblast growth factor 7
FGF10 fibroblast growth factor 10
FGFR3 fibroblast growth factor receptor 3
FGFR2 fibroblast growth factor receptor 2
FLT1 fms related receptor tyrosine kinase 1
FLT3LG fms related receptor tyrosine kinase 3 ligand
GNAI3 G protein subunit alpha i3
GNB1 G protein subunit beta 1
GNB3 G protein subunit beta 3
GNG11 G protein subunit gamma 11
GRB2 growth factor receptor bound protein 2
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
HDC histidine decarboxylase
HGF hepatocyte growth factor
HTR7 5-hydroxytryptamine receptor 7
IGF1R insulin like growth factor 1 receptor
IL12RB1 interleukin 12 receptor subunit beta 1
KDR kinase insert domain receptor
KIT KIT proto-oncogene, receptor tyrosine kinase
KRAS KRAS proto-oncogene, GTPase
AFDN afadin, adherens junction formation factor
FOXO4 forkhead box O4
NFKB1 nuclear factor kappa B subunit 1
NFKB2 nuclear factor kappa B subunit 2
NFKBIA NFKB inhibitor alpha
NGF nerve growth factor
NRAS NRAS proto-oncogene, GTPase
NTF3 neurotrophin 3
NTRK1 neurotrophic receptor tyrosine kinase 1
NTRK2 neurotrophic receptor tyrosine kinase 2
PAK2 p21 (RAC1) activated kinase 2
PDGFB platelet derived growth factor subunit B
PDGFRA platelet derived growth factor receptor alpha
PDGFRB platelet derived growth factor receptor beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PLA2G2A phospholipase A2 group IIA
PLA2G5 phospholipase A2 group V
PODXL podocalyxin like
PRELP proline and arginine rich end leucine rich repeat protein
PRKACB protein kinase cAMP-activated catalytic subunit beta
MAP2K2 mitogen-activated protein kinase kinase 2
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAC1 Rac family small GTPase 1
RALB RAS like proto-oncogene B
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
REL REL proto-oncogene, NF-kB subunit
RELB RELB proto-oncogene, NF-kB subunit
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
STK4 serine/threonine kinase 4
STXBP3 syntaxin binding protein 3
TEK TEK receptor tyrosine kinase
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
ZAP70 zeta chain of T cell receptor associated protein kinase 70
RAB7A RAB7A, member RAS oncogene family
FOSL1 FOS like 1, AP-1 transcription factor subunit
PLA2G4C phospholipase A2 group IVC
SYNGAP1 synaptic Ras GTPase activating protein 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
RASAL2 RAS protein activator like 2
RIN1 Ras and Rab interactor 1
GNA14 G protein subunit alpha 14
RAPGEF5 Rap guanine nucleotide exchange factor 5
DAZAP2 DAZ associated protein 2
GAB2 GRB2 associated binding protein 2
ACTR2 actin related protein 2
PAK4 p21 (RAC1) activated kinase 4
MAPRE2 microtubule associated protein RP/EB family member 2
RRAS2 RAS related 2
WDTC1 WD and tetratricopeptide repeats 1
ATP11B ATPase phospholipid transporting 11B (putative)
MED13L mediator complex subunit 13L
ARHGAP45 Rho GTPase activating protein 45
SHC2 SHC adaptor protein 2
TBK1 TANK binding kinase 1
PLA2G3 phospholipase A2 group III
CALML5 calmodulin like 5
SHC3 SHC adaptor protein 3
GNG2 G protein subunit gamma 2
SAMD4B sterile alpha motif domain containing 4B
TRERF1 transcriptional regulating factor 1
ADGRL4 adhesion G protein-coupled receptor L4
RASAL3 RAS protein activator like 3
CPED1 cadherin like and PC-esterase domain containing 1
RASSF5 Ras association domain family member 5
LCE3D late cornified envelope 3D
DNER delta/notch like EGF repeat containing
PRRT2 proline rich transmembrane protein 2
TMEM132B transmembrane protein 132B
TM4SF18 transmembrane 4 L six family member 18
PLA2G4E phospholipase A2 group IVE
C2CD4C C2 calcium dependent domain containing 4C
CCBE1 collagen and calcium binding EGF domains 1
SLC37A2 solute carrier family 37 member 2
C6orf223 chromosome 6 open reading frame 223
PLA2G4F phospholipase A2 group IVF
ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
PLA2G4D phospholipase A2 group IVD
TBC1D10C TBC1 domain family member 10C
Symbol Function*
Abl2 v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
Adcy7 adenylate cyclase 7
Angpt1 angiopoietin 1
Angpt2 angiopoietin 2
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Arf6 ADP-ribosylation factor 6
Rhoa ras homolog family member A
Bdnf brain derived neurotrophic factor
Calm1 calmodulin 1
Calm2 calmodulin 2
Calm3 calmodulin 3
Capns1 calpain, small subunit 1
Rb1cc1 RB1-inducible coiled-coil 1
Cd3d CD3 antigen, delta polypeptide
Cdc42 cell division cycle 42
Cdh5 cadherin 5
Coro1a coronin, actin binding protein 1A
Csf1r colony stimulating factor 1 receptor
Twist2 twist basic helix-loop-helix transcription factor 2
Dlg4 discs large MAGUK scaffold protein 4
Ednra endothelin receptor type A
Efna1 ephrin A1
Efna3 ephrin A3
Efna4 ephrin A4
Egfr epidermal growth factor receptor
Elk1 ELK1, member of ETS oncogene family
Fgf10 fibroblast growth factor 10
Fgf18 fibroblast growth factor 18
Fgf5 fibroblast growth factor 5
Fgf7 fibroblast growth factor 7
Fgfr2 fibroblast growth factor receptor 2
Fgfr3 fibroblast growth factor receptor 3
Flt1 FMS-like tyrosine kinase 1
Flt3 FMS-like tyrosine kinase 3
Flt4 FMS-like tyrosine kinase 4
Fosl1 fos-like antigen 1
Gab1 growth factor receptor bound protein 2-associated protein 1
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2
Gnb1 guanine nucleotide binding protein (G protein), beta 1
Gnb2 guanine nucleotide binding protein (G protein), beta 2
Gnb4 guanine nucleotide binding protein (G protein), beta 4
Gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
Gng10 guanine nucleotide binding protein (G protein), gamma 10
Gpc4 glypican 4
Grb2 growth factor receptor bound protein 2
Ptpn6 protein tyrosine phosphatase, non-receptor type 6
Hgf hepatocyte growth factor
Hras Harvey rat sarcoma virus oncogene
Htr7 5-hydroxytryptamine (serotonin) receptor 7
Ins1 insulin I
Ins2 insulin II
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3
Kdr kinase insert domain protein receptor
Kif1c kinesin family member 1C
Kras Kirsten rat sarcoma viral oncogene homolog
Ksr1 kinase suppressor of ras 1
Lat linker for activation of T cells
Lor loricrin
Mbd3 methyl-CpG binding domain protein 3
Met met proto-oncogene
Kitl kit ligand
Mras muscle and microspikes RAS
Usp34 ubiquitin specific peptidase 34
Septin2 septin 2
Nf1 neurofibromin 1
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
Ngf nerve growth factor
Ngfr nerve growth factor receptor (TNFR superfamily, member 16)
Nras neuroblastoma ras oncogene
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1
Pdgfa platelet derived growth factor, alpha
Pdgfb platelet derived growth factor, B polypeptide
Pdgfra platelet derived growth factor receptor, alpha polypeptide
Pdgfrb platelet derived growth factor receptor, beta polypeptide
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Pitpna phosphatidylinositol transfer protein, alpha
Prkca protein kinase C, alpha
Prkcb protein kinase C, beta
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid)
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent)
Pla2g5 phospholipase A2, group V
Plcg1 phospholipase C, gamma 1
Pld2 phospholipase D2
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Ptgfr prostaglandin F receptor
Ptgs1 prostaglandin-endoperoxide synthase 1
Ptgs2 prostaglandin-endoperoxide synthase 2
Ptprb protein tyrosine phosphatase, receptor type, B
Rac1 Rac family small GTPase 1
Rac2 Rac family small GTPase 2
Rasgrp2 RAS, guanyl releasing protein 2
Rasgrp1 RAS guanyl releasing protein 1
Rel reticuloendotheliosis oncogene
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B
Rgl2 ral guanine nucleotide dissociation stimulator-like 2
Ralbp1 ralA binding protein 1
Rras related RAS viral (r-ras) oncogene
Ccl22 chemokine (C-C motif) ligand 22
Cavin2 caveolae associated 2
Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Sox18 SRY (sex determining region Y)-box 18
Stxbp1 syntaxin binding protein 1
Tek TEK receptor tyrosine kinase
Tfpi2 tissue factor pathway inhibitor 2
Try4 trypsin 4
Vegfb vascular endothelial growth factor B
Vegfc vascular endothelial growth factor C
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Zap70 zeta-chain (TCR) associated protein kinase
Akt3 thymoma viral proto-oncogene 3
Map2k2 mitogen-activated protein kinase kinase 2
Map3k11 mitogen-activated protein kinase kinase kinase 11
Map4k2 mitogen-activated protein kinase kinase kinase kinase 2
Mapk1 mitogen-activated protein kinase 1
Mapk10 mitogen-activated protein kinase 10
Mapk3 mitogen-activated protein kinase 3
Podxl podocalyxin-like
Vapa vesicle-associated membrane protein, associated protein A
Rassf5 Ras association (RalGDS/AF-6) domain family member 5
Foxo4 forkhead box O4
Pdgfc platelet-derived growth factor, C polypeptide
Nudt3 nudix (nucleotide diphosphate linked moiety X)-type motif 3
Mtch1 mitochondrial carrier 1
Eid1 EP300 interacting inhibitor of differentiation 1
Gmfg glia maturation factor, gamma
Ralb v-ral simian leukemia viral oncogene B
Gng11 guanine nucleotide binding protein (G protein), gamma 11
Them5 thioesterase superfamily member 5
Clec14a C-type lectin domain family 14, member a
Gatad1 GATA zinc finger domain containing 1
Calcoco1 calcium binding and coiled coil domain 1
Calml3 calmodulin-like 3
Pak4 p21 (RAC1) activated kinase 4
Actr3 ARP3 actin-related protein 3
Calml4 calmodulin-like 4
Ecrg4 ECRG4 augurin precursor
Calm4 calmodulin 4
Csnk1g2 casein kinase 1, gamma 2
Mgat4b mannoside acetylglucosaminyltransferase 4, isoenzyme B
Mmrn2 multimerin 2
Aida axin interactor, dorsalization associated
Rap1a RAS-related protein 1a
Bptf bromodomain PHD finger transcription factor
Pak6 p21 (RAC1) activated kinase 6
Rap1b RAS related protein 1b
Rasa1 RAS p21 protein activator 1
Adgrf5 adhesion G protein-coupled receptor F5
Gm94 predicted gene 94
Rin1 Ras and Rab interactor 1
Plcg2 phospholipase C, gamma 2
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat)
Rasgrp3 RAS, guanyl releasing protein 3
Rapgefl1 Rap guanine nucleotide exchange factor (GEF)-like 1
Rab5a RAB5A, member RAS oncogene family
Pla2g4f phospholipase A2, group IVF
Shc4 SHC (Src homology 2 domain containing) family, member 4
Tns3 tensin 3
Rasal3 RAS protein activator like 3
Symbol Function*
Calm1 calmodulin 1
Calm3 calmodulin 3
Ets1 ETS proto-oncogene 1, transcription factor
Grin2b glutamate ionotropic receptor NMDA type subunit 2B
Hgf hepatocyte growth factor
Igf2 insulin-like growth factor 2
Igfbp3 insulin-like growth factor binding protein 3
Kras KRAS proto-oncogene, GTPase
Nf1 neurofibromin 1
Ngfr nerve growth factor receptor
Nras NRAS proto-oncogene, GTPase
Pdgfb platelet derived growth factor subunit B
Pdgfrb platelet derived growth factor receptor beta
Prkcg protein kinase C, gamma
Tgfa transforming growth factor alpha
Bcl2l1 Bcl2-like 1
Plaat3 phospholipase A and acyltransferase 3
Fgfr2 fibroblast growth factor receptor 2
Prkcb protein kinase C, beta
Calcrl calcitonin receptor like receptor
Pvr PVR cell adhesion molecule
Pld1 phospholipase D1
Ddn dendrin
Chrm1 cholinergic receptor, muscarinic 1
Acvrl1 activin A receptor like type 1
Pdgfra platelet derived growth factor receptor alpha
Fgf10 fibroblast growth factor 10
Fgf9 fibroblast growth factor 9
Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1
Mras muscle RAS oncogene homolog
Kdr kinase insert domain receptor
Agrn agrin
Ptpn11 protein tyrosine phosphatase, non-receptor type 11
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Gnai3 G protein subunit alpha i3
Rasa1 RAS p21 protein activator 1
Plcg1 phospholipase C, gamma 1
Afdn afadin, adherens junction formation factor
Plcg2 phospholipase C, gamma 2
Pla2g5 phospholipase A2, group V
Rasa3 RAS p21 protein activator 3
Pak2 p21 (RAC1) activated kinase 2
Pak3 p21 (RAC1) activated kinase 3
Rasgrp1 RAS guanyl releasing protein 1
Pla2g2a phospholipase A2 group IIA
Pik3r2 phosphoinositide-3-kinase regulatory subunit 2
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Mapk9 mitogen-activated protein kinase 9
Calm2 calmodulin 2
Mapk3 mitogen activated protein kinase 3
Cr1l complement C3b/C4b receptor 1 like
Flt1 Fms related receptor tyrosine kinase 1
Map2k2 mitogen activated protein kinase kinase 2
Ntrk1 neurotrophic receptor tyrosine kinase 1
Twist2 twist family bHLH transcription factor 2
Max MYC associated factor X
Adgrl4 adhesion G protein-coupled receptor L4
Gng11 G protein subunit gamma 11
Cdc42 cell division cycle 42
Rab5a RAB5A, member RAS oncogene family
Unc13b unc-13 homolog B
Rab2a RAB2A, member RAS oncogene family
Arf6 ADP-ribosylation factor 6
Mtpn myotrophin
Gng5 G protein subunit gamma 5
Pdgfc platelet derived growth factor C
Grb2 growth factor receptor bound protein 2
Lat linker for activation of T cells
Gnb2 G protein subunit beta 2
Msx1 msh homeobox 1
Nfkb1 nuclear factor kappa B subunit 1
Ntf3 neurotrophin 3
Rala RAS like proto-oncogene A
Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta
Fgfr3 fibroblast growth factor receptor 3
Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Gas7 growth arrest specific 7
Pla1a phospholipase A1 member A
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Shc1 SHC adaptor protein 1
Tek TEK receptor tyrosine kinase
Angpt2 angiopoietin 2
Vegfb vascular endothelial growth factor B
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta
Pgf placental growth factor
Kif1c kinesin family member 1C
Cdc42bpb CDC42 binding protein kinase beta
Vegfc vascular endothelial growth factor C
Gng10 G protein subunit gamma 10
Gng12 G protein subunit gamma 12
Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2
Itga6 integrin subunit alpha 6
Shc3 SHC adaptor protein 3
Ralb RAS like proto-oncogene B
Mapk1 mitogen activated protein kinase 1
Efna5 ephrin A5
Rhoa ras homolog family member A
Septin2 septin 2
Arf3 ADP-ribosylation factor 3
Map2k1 mitogen activated protein kinase kinase 1
Efna3 ephrin A3
Serinc5 serine incorporator 5
Inpp5j inositol polyphosphate-5-phosphatase J
Rap1b RAP1B, member of RAS oncogene family
Ipmk inositol polyphosphate multikinase
Syngap1 synaptic Ras GTPase activating protein 1
Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1
Rin1 Ras and Rab interactor 1
Adgrf5 adhesion G protein-coupled receptor F5
Gng8 G protein subunit gamma 8
Nradd neurotrophin receptor associated death domain
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Rab5c RAB5C, member RAS oncogene family
Fis1 fission, mitochondrial 1
Rab5b RAB5B, member RAS oncogene family
Mapkapk2 MAPK activated protein kinase 2
Rgl1 ral guanine nucleotide dissociation stimulator,-like 1
Pla2g3 phospholipase A2, group III
Actr2 actin related protein 2
Tnks tankyrase
Afap1l1 actin filament associated protein 1-like 1
Pak4 p21 (RAC1) activated kinase 4
Hras HRas proto-oncogene, GTPase
Mtch1 mitochondrial carrier 1
Lhfpl2 LHFPL tetraspan subfamily member 2
Man1a2 mannosidase, alpha, class 1A, member 2
Emcn endomucin
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Fbxo11 F-box protein 11
Foxo4 forkhead box O4
Tiam1 TIAM Rac1 associated GEF 1
Cyyr1 cysteine and tyrosine rich 1
Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase
S1pr3 sphingosine-1-phosphate receptor 3
Rela RELA proto-oncogene, NF-kB subunit
Map3k11 mitogen-activated protein kinase kinase kinase 11
Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Nfkb2 nuclear factor kappa B subunit 2
Efna4 ephrin A4
Ngf nerve growth factor
Mlf2 myeloid leukemia factor 2
Acer2 alkaline ceramidase 2
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Rasgrp3 RAS guanyl releasing protein 3
Clec14a C-type lectin domain containing 14A
Rasal3 RAS protein activator like 3
Arhgap45 Rho GTPase activating protein 45
Ptprb protein tyrosine phosphatase, receptor type, B
Sash3 SAM and SH3 domain containing 3
Vegfd vascular endothelial growth factor D
Rasal1 RAS protein activator like 1
Arpc5 actin related protein 2/3 complex, subunit 5
Gab1 GRB2-associated binding protein 1
Vasp vasodilator-stimulated phosphoprotein
Fgd5 FYVE, RhoGEF and PH domain containing 5
Rapgef5 Rap guanine nucleotide exchange factor 5
Mbd3 methyl-CpG binding domain protein 3
Rassf1 Ras association domain family member 1
Rac1 Rac family small GTPase 1
Tmem165 transmembrane protein 165
Ssbp4 single stranded DNA binding protein 4
Nkd1 NKD inhibitor of WNT signaling pathway 1
Rras2 RAS related 2
Epha2 Eph receptor A2
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein
Smim10l1 small integral membrane protein 10 like 1
LOC102547461 uncharacterized LOC102547461
Ksr1 kinase suppressor of ras 1
Symbol Function*
FLT1 fms related receptor tyrosine kinase 1
FGF2 fibroblast growth factor 2
IL12RB1 interleukin 12 receptor subunit beta 1
VEGFA vascular endothelial growth factor A
NGFR nerve growth factor receptor
FGF7 fibroblast growth factor 7
GRIN1 glutamate ionotropic receptor NMDA type subunit 1
ATP6V0A1 ATPase H+ transporting V0 subunit a1
EPHA2 EPH receptor A2
CDH5 cadherin 5
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
SMAP2 small ArfGAP2
ASXL2 ASXL transcriptional regulator 2
RASSF5 Ras association domain family member 5
SHOC2 SHOC2 leucine rich repeat scaffold protein
LOC696306 T cell receptor beta variable 3-1
RAC2 Rac family small GTPase 2
TBC1D4 TBC1 domain family member 4
PDGFRA platelet derived growth factor receptor alpha
ANGPT1 angiopoietin 1
STUB1 STIP1 homology and U-box containing protein 1
FOXO4 forkhead box O4
KDR kinase insert domain receptor
IGF1 insulin like growth factor 1
CALM1 calmodulin 1
MAPK1 mitogen-activated protein kinase 1
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
EGF epidermal growth factor
LOC698785 uncharacterized LOC698785
HRAS HRas proto-oncogene, GTPase
GNGT2 G protein subunit gamma transducin 2
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
ERI1 exoribonuclease 1
CD3E CD3e molecule
VEGFC vascular endothelial growth factor C
CD3D CD3d molecule
TMEM125 transmembrane protein 125
ZNF292 zinc finger protein 292
PLA2G6 phospholipase A2 group VI
PDGFC platelet derived growth factor C
MAFF MAF bZIP transcription factor F
PRKCB protein kinase C beta
IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
FCHSD1 FCH and double SH3 domains 1
UBE2R2 ubiquitin conjugating enzyme E2 R2
LRCH4 leucine rich repeats and calponin homology domain containing 4
GRB2 growth factor receptor bound protein 2
SASH3 SAM and SH3 domain containing 3
PRR13 proline rich 13
LOC703029 immunoglobulin lambda-1 light chain-like
DES desmin
GNB1 G protein subunit beta 1
RALA RAS like proto-oncogene A
PARVA parvin alpha
GNAI2 G protein subunit alpha i2
RASGRP1 RAS guanyl releasing protein 1
B4GALT2 beta-1,4-galactosyltransferase 2
RAP1A RAP1A, member of RAS oncogene family
LAT linker for activation of T cells
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
CAPZA1 capping actin protein of muscle Z-line subunit alpha 1
INSR insulin receptor
PAK3 p21 (RAC1) activated kinase 3
RHOA ras homolog family member A
RAB7A RAB7A, member RAS oncogene family
LLGL1 LLGL scribble cell polarity complex component 1
TEK TEK receptor tyrosine kinase
CDC42 cell division cycle 42
PDGFA platelet derived growth factor subunit A
KRAS KRAS proto-oncogene, GTPase
MARCHF8 membrane associated ring-CH-type finger 8
PTCHD4 patched domain containing 4
CLMP CXADR like membrane protein
ARF6 ADP ribosylation factor 6
GNG10 G protein subunit gamma 10
IGF1R insulin like growth factor 1 receptor
HGF hepatocyte growth factor
RAB5B RAB5B, member RAS oncogene family
MAPK3 mitogen-activated protein kinase 3
NRAS NRAS proto-oncogene, GTPase
SLC22A3 solute carrier family 22 member 3
CHUK component of inhibitor of nuclear factor kappa B kinase complex
PCBP1 poly(rC) binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
PRKACB protein kinase cAMP-activated catalytic subunit beta
NTRK2 neurotrophic receptor tyrosine kinase 2
LUM lumican
NFAM1 NFAT activating protein with ITAM motif 1
PAK2 p21 (RAC1) activated kinase 2
NFKB1 nuclear factor kappa B subunit 1
MAP2K1 mitogen-activated protein kinase kinase 1
GNG5 G protein subunit gamma 5
VEGFD vascular endothelial growth factor D
PLA1A phospholipase A1 member A
BRAP BRCA1 associated protein
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
NHS NHS actin remodeling regulator
TSPOAP1 TSPO associated protein 1
RALGDS ral guanine nucleotide dissociation stimulator
ETS1 ETS proto-oncogene 1, transcription factor
AKT3 AKT serine/threonine kinase 3
ARPC5 actin related protein 2/3 complex subunit 5
RASA2 RAS p21 protein activator 2
ITK IL2 inducible T cell kinase
FGFR2 fibroblast growth factor receptor 2
LOC716034 signal-regulatory protein gamma
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
CALM3 calmodulin 3
PLA2G4A phospholipase A2 group IVA
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
KIAA2026 KIAA2026
EFNA1 ephrin A1
BAD BCL2 associated agonist of cell death
RAC1 Rac family small GTPase 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
REL REL proto-oncogene, NF-kB subunit
INPP5D inositol polyphosphate-5-phosphatase D
SYNGAP1 synaptic Ras GTPase activating protein 1
RAP1B RAP1B, member of RAS oncogene family
RGL2 ral guanine nucleotide dissociation stimulator like 2
RASAL2 RAS protein activator like 2
RASAL3 RAS protein activator like 3
FLT3LG fms related receptor tyrosine kinase 3 ligand
GNB2 G protein subunit beta 2
MTCH1 mitochondrial carrier 1
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
RASGRP4 RAS guanyl releasing protein 4
RASA4B RAS p21 protein activator 4B
PLD2 phospholipase D2
CFL1 cofilin 1
PLAAT3 phospholipase A and acyltransferase 3
PLAAT4 phospholipase A and acyltransferase 4
CC2D2B coiled-coil and C2 domain containing 2B
GNG12 G protein subunit gamma 12
C12H2orf88 chromosome 12 C2orf88 homolog
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
PLA2G4B phospholipase A2 group IVB
LOC106999340 immunoglobulin kappa light chain
LOC106999345 T cell receptor alpha variable 26-1-like
LOC114677059 uncharacterized LOC114677059
Symbol Function*
MET MET proto-oncogene, receptor tyrosine kinase
MAOA monoamine oxidase A
KITLG KIT ligand
PRKACA protein kinase cAMP-activated catalytic subunit alpha
GNGT2 G protein subunit gamma transducin 2
BCL2L1 BCL2 like 1
ANGPT1 angiopoietin 1
TEK TEK receptor tyrosine kinase
KIT KIT proto-oncogene, receptor tyrosine kinase
EDNRB endothelin receptor type B
NRAS NRAS proto-oncogene, GTPase
RAB5C RAB5C, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
FGFR2 fibroblast growth factor receptor 2
NFKB1 nuclear factor kappa B subunit 1
PDGFRA platelet derived growth factor receptor alpha
IGF1R insulin like growth factor 1 receptor
AKT3 AKT serine/threonine kinase 3
REL REL proto-oncogene, NF-kB subunit
RALA RAS like proto-oncogene A
AP2S1 adaptor related protein complex 2 subunit sigma 1
CALM3 calmodulin 3
DDA1 DET1 and DDB1 associated 1
MRAS muscle RAS oncogene homolog
STK4 serine/threonine kinase 4
MAPK8 mitogen-activated protein kinase 8
CHUK component of inhibitor of nuclear factor kappa B kinase complex
SHOC2 SHOC2 leucine rich repeat scaffold protein
NRP1 neuropilin 1
PLA2G5 phospholipase A2 group V
RASGRP1 RAS guanyl releasing protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
PDGFD platelet derived growth factor D
GNB2 G protein subunit beta 2
ARHGAP29 Rho GTPase activating protein 29
RGL1 ral guanine nucleotide dissociation stimulator like 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
RASAL2 RAS protein activator like 2
NF1 neurofibromin 1
RALGDS ral guanine nucleotide dissociation stimulator
PLA2G6 phospholipase A2 group VI
RAC2 Rac family small GTPase 2
SYNGAP1 synaptic Ras GTPase activating protein 1
KDR kinase insert domain receptor
KDM7A lysine demethylase 7A
VEGFC vascular endothelial growth factor C
GRB2 growth factor receptor bound protein 2
BAD BCL2 associated agonist of cell death
AP2A1 adaptor related protein complex 2 subunit alpha 1
RELB RELB proto-oncogene, NF-kB subunit
FKBP8 FKBP prolyl isomerase 8
INSR insulin receptor
RASA2 RAS p21 protein activator 2
CALCOCO1 calcium binding and coiled-coil domain 1
BIN2 bridging integrator 2
PLCE1 phospholipase C epsilon 1
NFKB2 nuclear factor kappa B subunit 2
CALML5 calmodulin like 5
KIFC3 kinesin family member C3
PLA2G2D phospholipase A2 group IID
EPHA2 EPH receptor A2
SHC4 SHC adaptor protein 4
NEO1 neogenin 1
TIAM1 TIAM Rac1 associated GEF 1
UBASH3A ubiquitin associated and SH3 domain containing A
TIGIT T cell immunoreceptor with Ig and ITIM domains
CD84 CD84 molecule
FGFR3 fibroblast growth factor receptor 3
CSF1R colony stimulating factor 1 receptor
ETS1 ETS proto-oncogene 1, transcription factor
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
CORO1A coronin 1A
PRKCB protein kinase C beta
UBN1 ubinuclein 1
RHBDL1 rhomboid like 1
MAPKAPK2 MAPK activated protein kinase 2
EFNA4 ephrin A4
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
AKT1 AKT serine/threonine kinase 1
FMNL1 formin like 1
EGFL7 EGF like domain multiple 7
PDGFA platelet derived growth factor subunit A
VEGFD vascular endothelial growth factor D
CALML6 calmodulin like 6
GNG4 G protein subunit gamma 4
ANGPT2 angiopoietin 2
PAK1 p21 (RAC1) activated kinase 1
LAT linker for activation of T cells
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
BICC1 BicC family RNA binding protein 1
PLA2G4D phospholipase A2 group IVD
EMCN endomucin
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
RASAL3 RAS protein activator like 3
PECAM1 platelet and endothelial cell adhesion molecule 1
PRR7 proline rich 7, synaptic
PXYLP1 2-phosphoxylose phosphatase 1
RASGRP3 RAS guanyl releasing protein 3
MAP2K2 mitogen-activated protein kinase kinase 2
SHC2 SHC adaptor protein 2
PWWP3A PWWP domain containing 3A, DNA repair factor
CNFN cornifelin
DOCK9 dedicator of cytokinesis 9
ZAP70 zeta chain of T cell receptor associated protein kinase 70
ZBED6 zinc finger BED-type containing 6
LOC100683001 small integral membrane protein 10-like protein 2A
FOXO4 forkhead box O4
RAPGEF5 Rap guanine nucleotide exchange factor 5
PRKCG protein kinase C gamma
FGFR1 fibroblast growth factor receptor 1
EFNA3 ephrin A3
LOC102153034 calmodulin-like protein 3
RAC3 Rac family small GTPase 3
EFNA2 ephrin A2
LOC119865433 uncharacterized LOC119865433
Symbol Function*
MET MET proto-oncogene, receptor tyrosine kinase
BCL2L1 BCL2 like 1
VEGFD vascular endothelial growth factor D
CSF1R colony stimulating factor 1 receptor
KIT KIT proto-oncogene, receptor tyrosine kinase
INS insulin
HRAS HRas proto-oncogene, GTPase
INSR insulin receptor
FGF2 fibroblast growth factor 2
PDGFB platelet derived growth factor subunit B
NFKB1 nuclear factor kappa B subunit 1
IGF1R insulin like growth factor 1 receptor
EGFR epidermal growth factor receptor
CTRC chymotrypsin C
MAP2K1 mitogen-activated protein kinase kinase 1
KCNS3 potassium voltage-gated channel modifier subfamily S member 3
RALBP1 ralA binding protein 1
SHROOM4 shroom family member 4
PHF3 PHD finger protein 3
PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
PLA2G4E phospholipase A2 group IVE
PLA2G4D phospholipase A2 group IVD
PAK2 p21 (RAC1) activated kinase 2
MORC3 MORC family CW-type zinc finger 3
SEPTIN6 septin 6
RHOA ras homolog family member A
PLD1 phospholipase D1
STX12 syntaxin 12
PDGFRB platelet derived growth factor receptor beta
MAPK9 mitogen-activated protein kinase 9
VGLL3 vestigial like family member 3
PDGFD platelet derived growth factor D
RASGRP3 RAS guanyl releasing protein 3
PLSCR4 phospholipid scramblase 4
PTPN11 protein tyrosine phosphatase non-receptor type 11
EFNA5 ephrin A5
FGFR1 fibroblast growth factor receptor 1
SEPTIN1 septin 1
PJA2 praja ring finger ubiquitin ligase 2
FMNL1 formin like 1
ANGPT1 angiopoietin 1
MAPK1 mitogen-activated protein kinase 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
TRIM72 tripartite motif containing 72
GAB1 GRB2 associated binding protein 1
RAPGEF5 Rap guanine nucleotide exchange factor 5
NAPA NSF attachment protein alpha
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
GNG11 G protein subunit gamma 11
PRKCB protein kinase C beta
FKBP10 FKBP prolyl isomerase 10
RASSF5 Ras association domain family member 5
CALHM5 calcium homeostasis modulator family member 5
NUDT6 nudix hydrolase 6
KDR kinase insert domain receptor
FGF10 fibroblast growth factor 10
RASAL3 RAS protein activator like 3
LOC101090719 HRAS-like suppressor 3
PDGFRA platelet derived growth factor receptor alpha
PLCB2 phospholipase C beta 2
NRG2 neuregulin 2
RALA RAS like proto-oncogene A
CALM3 calmodulin 3
RASGRF2 Ras protein specific guanine nucleotide releasing factor 2
STK4 serine/threonine kinase 4
LOC101091201 serine/threonine-protein kinase PAK 6
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
ANGPT4 angiopoietin 4
CSF1 colony stimulating factor 1
LOC101091541 phosphatidylinositol phosphatase PTPRQ
GNG3 G protein subunit gamma 3
PLA2G2D phospholipase A2 group IID
GNB4 G protein subunit beta 4
TBK1 TANK binding kinase 1
TEK TEK receptor tyrosine kinase
HTR7 5-hydroxytryptamine receptor 7
ITGA6 integrin subunit alpha 6
MRAS muscle RAS oncogene homolog
CDC42SE2 CDC42 small effector 2
CC2D2A coiled-coil and C2 domain containing 2A
PIK3R3 phosphoinositide-3-kinase regulatory subunit 3
GNB2 G protein subunit beta 2
LAT linker for activation of T cells
FZD4 frizzled class receptor 4
TMOD3 tropomodulin 3
SDK1 sidekick cell adhesion molecule 1
TRIOBP TRIO and F-actin binding protein
PODXL podocalyxin like
SHOC2 SHOC2 leucine rich repeat scaffold protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
RASGRP2 RAS guanyl releasing protein 2
RASGRP4 RAS guanyl releasing protein 4
CALM1 calmodulin 1
VASP vasodilator stimulated phosphoprotein
EFNA3 ephrin A3
PRKACB protein kinase cAMP-activated catalytic subunit beta
PLA2G1B phospholipase A2 group IB
CHUK component of inhibitor of nuclear factor kappa B kinase complex
PGF placental growth factor
RAP1B RAP1B, member of RAS oncogene family
LOC101096188 sialic acid-binding Ig-like lectin 5
PLA2G3 phospholipase A2 group III
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PRKG1 protein kinase cGMP-dependent 1
SNX17 sorting nexin 17
GNG2 G protein subunit gamma 2
LARP6 La ribonucleoprotein 6, translational regulator
FGF7 fibroblast growth factor 7
MTMR1 myotubularin related protein 1
STK10 serine/threonine kinase 10
SMAP2 small ArfGAP2
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
SHC4 SHC adaptor protein 4
ZNF445 zinc finger protein 445
FLT3 fms related receptor tyrosine kinase 3
MOB1A MOB kinase activator 1A
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
GRB2 growth factor receptor bound protein 2
RAB5A RAB5A, member RAS oncogene family
CALML4 calmodulin like 4
FHIP1A FHF complex subunit HOOK interacting protein 1A
RAC1 Rac family small GTPase 1
ADGRF5 adhesion G protein-coupled receptor F5
ANGPT2 angiopoietin 2
LOC102902292 uncharacterized LOC102902292
NRARP NOTCH regulated ankyrin repeat protein
LOC109494706 uncharacterized LOC109494706
LOC109495407 uncharacterized LOC109495407
RGL2 ral guanine nucleotide dissociation stimulator like 2
LOC111556187 calmodulin-like protein 4
EFNA2 ephrin A2
LOC111557610 uncharacterized LOC111557610


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