COXPRESdb : GeneID search result

[←][→] mcc MAPK1 Gene

functional annotation

Function

mitogen-activated protein kinase 1

GO BP

GO CC

GO MF

KEGG

mcc01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (79 genes)

mcc01522 [list] [network] Endocrine resistance (98 genes)

mcc01524 [list] [network] Platinum drug resistance (86 genes)

mcc04010 [list] [network] MAPK signaling pathway (301 genes)

mcc04012 [list] [network] ErbB signaling pathway (85 genes)

mcc04014 [list] [network] Ras signaling pathway (250 genes)

mcc04015 [list] [network] Rap1 signaling pathway (229 genes)

mcc04022 [list] [network] cGMP-PKG signaling pathway (169 genes)

mcc04024 [list] [network] cAMP signaling pathway (226 genes)

mcc04062 [list] [network] Chemokine signaling pathway (200 genes)

mcc04066 [list] [network] HIF-1 signaling pathway (119 genes)

mcc04068 [list] [network] FoxO signaling pathway (131 genes)

mcc04071 [list] [network] Sphingolipid signaling pathway (120 genes)

mcc04072 [list] [network] Phospholipase D signaling pathway (168 genes)

mcc04114 [list] [network] Oocyte meiosis (126 genes)

mcc04140 [list] [network] Autophagy - animal (147 genes)

mcc04150 [list] [network] mTOR signaling pathway (155 genes)

mcc04151 [list] [network] PI3K-Akt signaling pathway (381 genes)

mcc04210 [list] [network] Apoptosis (150 genes)

mcc04218 [list] [network] Cellular senescence (174 genes)

mcc04261 [list] [network] Adrenergic signaling in cardiomyocytes (153 genes)

mcc04270 [list] [network] Vascular smooth muscle contraction (142 genes)

mcc04350 [list] [network] TGF-beta signaling pathway (94 genes)

mcc04360 [list] [network] Axon guidance (182 genes)

mcc04370 [list] [network] VEGF signaling pathway (58 genes)

mcc04371 [list] [network] Apelin signaling pathway (142 genes)

mcc04380 [list] [network] Osteoclast differentiation (131 genes)

mcc04510 [list] [network] Focal adhesion (205 genes)

mcc04520 [list] [network] Adherens junction (72 genes)

mcc04540 [list] [network] Gap junction (94 genes)

mcc04550 [list] [network] Signaling pathways regulating pluripotency of stem cells (144 genes)

mcc04611 [list] [network] Platelet activation (128 genes)

mcc04613 [list] [network] Neutrophil extracellular trap formation (214 genes)

mcc04620 [list] [network] Toll-like receptor signaling pathway (108 genes)

mcc04621 [list] [network] NOD-like receptor signaling pathway (197 genes)

mcc04625 [list] [network] C-type lectin receptor signaling pathway (108 genes)

mcc04650 [list] [network] Natural killer cell mediated cytotoxicity (142 genes)

mcc04657 [list] [network] IL-17 signaling pathway (101 genes)

mcc04658 [list] [network] Th1 and Th2 cell differentiation (99 genes)

mcc04659 [list] [network] Th17 cell differentiation (117 genes)

mcc04660 [list] [network] T cell receptor signaling pathway (107 genes)

mcc04662 [list] [network] B cell receptor signaling pathway (96 genes)

mcc04664 [list] [network] Fc epsilon RI signaling pathway (78 genes)

mcc04666 [list] [network] Fc gamma R-mediated phagocytosis (106 genes)

mcc04668 [list] [network] TNF signaling pathway (115 genes)

mcc04713 [list] [network] Circadian entrainment (103 genes)

mcc04720 [list] [network] Long-term potentiation (70 genes)

mcc04722 [list] [network] Neurotrophin signaling pathway (122 genes)

mcc04723 [list] [network] Retrograde endocannabinoid signaling (159 genes)

mcc04724 [list] [network] Glutamatergic synapse (115 genes)

mcc04725 [list] [network] Cholinergic synapse (114 genes)

mcc04726 [list] [network] Serotonergic synapse (118 genes)

mcc04730 [list] [network] Long-term depression (61 genes)

mcc04810 [list] [network] Regulation of actin cytoskeleton (221 genes)

mcc04910 [list] [network] Insulin signaling pathway (141 genes)

mcc04912 [list] [network] GnRH signaling pathway (97 genes)

mcc04914 [list] [network] Progesterone-mediated oocyte maturation (93 genes)

mcc04915 [list] [network] Estrogen signaling pathway (144 genes)

mcc04916 [list] [network] Melanogenesis (103 genes)

mcc04917 [list] [network] Prolactin signaling pathway (70 genes)

mcc04919 [list] [network] Thyroid hormone signaling pathway (124 genes)

mcc04921 [list] [network] Oxytocin signaling pathway (163 genes)

mcc04926 [list] [network] Relaxin signaling pathway (133 genes)

mcc04928 [list] [network] Parathyroid hormone synthesis, secretion and action (109 genes)

mcc04929 [list] [network] GnRH secretion (64 genes)

mcc04930 [list] [network] Type II diabetes mellitus (47 genes)

mcc04933 [list] [network] AGE-RAGE signaling pathway in diabetic complications (102 genes)

mcc04934 [list] [network] Cushing syndrome (161 genes)

mcc04935 [list] [network] Growth hormone synthesis, secretion and action (128 genes)

mcc04960 [list] [network] Aldosterone-regulated sodium reabsorption (37 genes)

mcc05010 [list] [network] Alzheimer disease (441 genes)

mcc05020 [list] [network] Prion disease (329 genes)

mcc05022 [list] [network] Pathways of neurodegeneration - multiple diseases (540 genes)

mcc05034 [list] [network] Alcoholism (204 genes)

mcc05132 [list] [network] Salmonella infection (264 genes)

mcc05133 [list] [network] Pertussis (85 genes)

mcc05135 [list] [network] Yersinia infection (153 genes)

mcc05140 [list] [network] Leishmaniasis (91 genes)

mcc05142 [list] [network] Chagas disease (111 genes)

mcc05145 [list] [network] Toxoplasmosis (123 genes)

mcc05152 [list] [network] Tuberculosis (206 genes)

mcc05160 [list] [network] Hepatitis C (173 genes)

mcc05161 [list] [network] Hepatitis B (180 genes)

mcc05163 [list] [network] Human cytomegalovirus infection (257 genes)

mcc05164 [list] [network] Influenza A (191 genes)

mcc05165 [list] [network] Human papillomavirus infection (352 genes)

mcc05166 [list] [network] Human T-cell leukemia virus 1 infection (247 genes)

mcc05167 [list] [network] Kaposi sarcoma-associated herpesvirus infection (227 genes)

mcc05170 [list] [network] Human immunodeficiency virus 1 infection (247 genes)

mcc05171 [list] [network] Coronavirus disease - COVID-19 (371 genes)

mcc05200 [list] [network] Pathways in cancer (573 genes)

mcc05203 [list] [network] Viral carcinogenesis (223 genes)

mcc05205 [list] [network] Proteoglycans in cancer (211 genes)

mcc05206 [list] [network] MicroRNAs in cancer (293 genes)

mcc05207 [list] [network] Chemical carcinogenesis - receptor activation (215 genes)

mcc05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (272 genes)

mcc05210 [list] [network] Colorectal cancer (107 genes)

mcc05211 [list] [network] Renal cell carcinoma (72 genes)

mcc05212 [list] [network] Pancreatic cancer (88 genes)

mcc05213 [list] [network] Endometrial cancer (61 genes)

mcc05214 [list] [network] Glioma (79 genes)

mcc05215 [list] [network] Prostate cancer (97 genes)

mcc05216 [list] [network] Thyroid cancer (39 genes)

mcc05218 [list] [network] Melanoma (74 genes)

mcc05219 [list] [network] Bladder cancer (41 genes)

mcc05220 [list] [network] Chronic myeloid leukemia (80 genes)

mcc05221 [list] [network] Acute myeloid leukemia (69 genes)

mcc05223 [list] [network] Non-small cell lung cancer (75 genes)

mcc05224 [list] [network] Breast cancer (150 genes)

mcc05225 [list] [network] Hepatocellular carcinoma (177 genes)

mcc05226 [list] [network] Gastric cancer (153 genes)

mcc05230 [list] [network] Central carbon metabolism in cancer (76 genes)

mcc05231 [list] [network] Choline metabolism in cancer (107 genes)

mcc05235 [list] [network] PD-L1 expression and PD-1 checkpoint pathway in cancer (93 genes)

mcc05417 [list] [network] Lipid and atherosclerosis (237 genes)

Protein

XP_015005287.1

BLAST

XP_015005287.1

Orthologous

[Ortholog page] MAPK1 (hsa) MAPK3 (hsa) MAPK7 (hsa) Mapk7 (mmu) Mapk1 (mmu) Mapk3 (mmu) Erk7 (dme) Mapk3 (rno) Mapk7 (rno) Mapk1 (rno) mpk-2 (cel) mpk-1 (cel) mapk-15 (cel) pmk-3 (cel) sma-5 (cel) MAPK15 (hsa) Mapk15 (rno) Mapk15 (mmu) F09C12.2 (cel) mapk1 (dre) MAPK3 (gga) mapk3 (dre) MAPK15 (gga) MAPK1 (cfa) MAPK15 (cfa) MAPK7 (cfa) mapk7 (dre) mapk15 (dre) MAPK7 (mcc) MAPK3 (mcc) FUS3 (sce) KSS1 (sce) KDX1 (sce) SMK1 (sce) SLT2 (sce) p38c (dme) rl (dme) MAPK15 (mcc) MAPK3 (cfa) MAPK1 (fca) MAPK3 (fca) MAPK15 (fca) MAPK7 (fca)

Subcellular
localization
wolf

cyto 8, cyto_nucl 5, nucl 1

(predict for XP_015005287.1)

Gene coexpression

Network^*for
coexpressed
genes

[Cytoscape]

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
mcc04022	cGMP-PKG signaling pathway	4
mcc04919	Thyroid hormone signaling pathway	4
mcc04114	Oocyte meiosis	4
mcc05010	Alzheimer disease	4
mcc05022	Pathways of neurodegeneration - multiple diseases	4

Genes directly connected with MAPK1 on the network
coex z^*	Locus	Function^*	Coexpression detail	Entrez Gene ID^*
7.1	JAK1	Janus kinase 1	[detail]	677689
6.6	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	[detail]	709723
6.1	NCOA1	nuclear receptor coactivator 1	[detail]	718524
6.0	PPP3CA	protein phosphatase 3 catalytic subunit alpha	[detail]	709773
5.8	KLHL12	kelch like family member 12	[detail]	705991
5.1	PTPRJ	protein tyrosine phosphatase receptor type J	[detail]	710347

Coexpressed
gene list

[Coexpressed gene list for MAPK1]

Gene expression

All samples

[Expression pattern for all samples]

Tissue specificity^*

Link to other DBs
Entrez Gene ID	698569
Refseq ID (protein)	XP_015005287.1

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