[←][→] mmu  Pdgfra Gene
functional annotation
Function   platelet derived growth factor receptor, alpha polypeptide  
GO BP
GO:0035790 [list] [network] platelet-derived growth factor receptor-alpha signaling pathway  (1 genes)  IDA ISO  
GO:0038091 [list] [network] positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway  (3 genes)  ISO  
GO:0061047 [list] [network] positive regulation of branching involved in lung morphogenesis  (3 genes)  ISO  
GO:0072277 [list] [network] metanephric glomerular capillary formation  (3 genes)  IGI  
GO:0060437 [list] [network] lung growth  (7 genes)  ISO  
GO:2000739 [list] [network] regulation of mesenchymal stem cell differentiation  (8 genes)  ISO  
GO:0001553 [list] [network] luteinization  (10 genes)  IGI IMP  
GO:0033327 [list] [network] Leydig cell differentiation  (11 genes)  IMP  
GO:0055003 [list] [network] cardiac myofibril assembly  (18 genes)  IGI  
GO:0010544 [list] [network] negative regulation of platelet activation  (19 genes)  ISO  
GO:0048557 [list] [network] embryonic digestive tract morphogenesis  (20 genes)  IMP  
GO:0050872 [list] [network] white fat cell differentiation  (21 genes)  IMP  
GO:0008210 [list] [network] estrogen metabolic process  (23 genes)  IGI  
GO:0030539 [list] [network] male genitalia development  (23 genes)  IMP  
GO:0030325 [list] [network] adrenal gland development  (26 genes)  IGI  
GO:0023019 [list] [network] signal transduction involved in regulation of gene expression  (27 genes)  IDA  
GO:0061298 [list] [network] retina vasculature development in camera-type eye  (27 genes)  IGI  
GO:0070527 [list] [network] platelet aggregation  (28 genes)  ISO  
GO:0043552 [list] [network] positive regulation of phosphatidylinositol 3-kinase activity  (31 genes)  ISO  
GO:0010863 [list] [network] positive regulation of phospholipase C activity  (34 genes)  ISO  
GO:0060325 [list] [network] face morphogenesis  (40 genes)  IMP  
GO:0048008 [list] [network] platelet-derived growth factor receptor signaling pathway  (41 genes)  IMP ISO  
GO:0048701 [list] [network] embryonic cranial skeleton morphogenesis  (55 genes)  IBA IMP  
GO:0048146 [list] [network] positive regulation of fibroblast proliferation  (70 genes)  ISO  
GO:0048015 [list] [network] phosphatidylinositol-mediated signaling  (73 genes)  ISO  
GO:0042475 [list] [network] odontogenesis of dentin-containing tooth  (79 genes)  IMP  
GO:0018108 [list] [network] peptidyl-tyrosine phosphorylation  (89 genes)  IDA ISO  
GO:0060021 [list] [network] roof of mouth development  (101 genes)  IMP  
GO:0008585 [list] [network] female gonad development  (105 genes)  IGI  
GO:0034614 [list] [network] cellular response to reactive oxygen species  (105 genes)  ISO  
GO:0002244 [list] [network] hematopoietic progenitor cell differentiation  (144 genes)  IMP  
GO:0071230 [list] [network] cellular response to amino acid stimulus  (173 genes)  IDA  
GO:0050731 [list] [network] positive regulation of peptidyl-tyrosine phosphorylation  (191 genes)  ISO  
GO:0046777 [list] [network] protein autophosphorylation  (194 genes)  IDA ISO  
GO:0060326 [list] [network] cell chemotaxis  (208 genes)  IMP ISO  
GO:0030324 [list] [network] lung development  (226 genes)  IMP  
GO:0050920 [list] [network] regulation of chemotaxis  (228 genes)  ISO  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (228 genes)  ISO  
GO:0042060 [list] [network] wound healing  (252 genes)  IMP  
GO:0048705 [list] [network] skeletal system morphogenesis  (255 genes)  IMP  
GO:0030198 [list] [network] extracellular matrix organization  (269 genes)  IMP  
GO:0007204 [list] [network] positive regulation of cytosolic calcium ion concentration  (309 genes)  ISO  
GO:0007169 [list] [network] transmembrane receptor protein tyrosine kinase signaling pathway  (365 genes)  IBA  
GO:0033674 [list] [network] positive regulation of kinase activity  (435 genes)  IBA  
GO:0006935 [list] [network] chemotaxis  (502 genes)  IEA  
GO:0001701 [list] [network] in utero embryonic development  (547 genes)  IMP  
GO:0030335 [list] [network] positive regulation of cell migration  (567 genes)  ISO  
GO:0006468 [list] [network] protein phosphorylation  (665 genes)  IEA  
GO:0016310 [list] [network] phosphorylation  (836 genes)  IEA  
GO:0016477 [list] [network] cell migration  (896 genes)  IMP  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (1011 genes)  ISO  
GO:0009887 [list] [network] animal organ morphogenesis  (1068 genes)  IMP  
GO:0009653 [list] [network] anatomical structure morphogenesis  (2327 genes)  IMP  
GO:0007275 [list] [network] multicellular organism development  (5017 genes)  IBA  
GO CC
GO:0005902 [list] [network] microvillus  (103 genes)  IDA  
GO:0043235 [list] [network] receptor complex  (412 genes)  IBA  
GO:0009897 [list] [network] external side of plasma membrane  (621 genes)  IDA  
GO:0005929 [list] [network] cilium  (703 genes)  IDA  
GO:0030424 [list] [network] axon  (732 genes)  ISO  
GO:0009986 [list] [network] cell surface  (1142 genes)  IDA  
GO:0005794 [list] [network] Golgi apparatus  (1525 genes)  IDA  
GO:0005887 [list] [network] integral component of plasma membrane  (1555 genes)  IBA ISO  
GO:0031226 [list] [network] intrinsic component of plasma membrane  (1644 genes)  ISO  
GO:0030054 [list] [network] cell junction  (2071 genes)  ISO  
GO:0042995 [list] [network] cell projection  (2594 genes)  IEA  
GO:0005654 [list] [network] nucleoplasm  (3580 genes)  ISO  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  ISO  
GO:0032991 [list] [network] protein-containing complex  (5540 genes)  ISO  
GO:0016021 [list] [network] integral component of membrane  (5954 genes)  IEA  
GO:0005634 [list] [network] nucleus  (7226 genes)  IDA ISO  
GO:0016020 [list] [network] membrane  (9571 genes)  IEA  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IDA ISO  
GO MF
GO:0005018 [list] [network] platelet-derived growth factor alpha-receptor activity  (1 genes)  IBA IDA ISO  
GO:0038085 [list] [network] vascular endothelial growth factor binding  (6 genes)  ISO  
GO:0005021 [list] [network] vascular endothelial growth factor-activated receptor activity  (7 genes)  ISO  
GO:0048407 [list] [network] platelet-derived growth factor binding  (12 genes)  IBA IDA ISO TAS  
GO:0005161 [list] [network] platelet-derived growth factor receptor binding  (14 genes)  ISO  
GO:0043548 [list] [network] phosphatidylinositol 3-kinase binding  (41 genes)  ISO  
GO:0004714 [list] [network] transmembrane receptor protein tyrosine kinase activity  (62 genes)  IBA ISO  
GO:0004713 [list] [network] protein tyrosine kinase activity  (134 genes)  IEA  
GO:0019838 [list] [network] growth factor binding  (151 genes)  IBA  
GO:0004672 [list] [network] protein kinase activity  (583 genes)  ISO  
GO:0016301 [list] [network] kinase activity  (740 genes)  IEA  
GO:0042803 [list] [network] protein homodimerization activity  (780 genes)  ISO  
GO:0005524 [list] [network] ATP binding  (1396 genes)  IEA  
GO:0044877 [list] [network] protein-containing complex binding  (1549 genes)  IDA  
GO:0000166 [list] [network] nucleotide binding  (2052 genes)  IEA  
GO:0016740 [list] [network] transferase activity  (2235 genes)  IEA  
KEGG mmu01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (79 genes)
mmu04010 [list] [network] MAPK signaling pathway (294 genes)
mmu04014 [list] [network] Ras signaling pathway (232 genes)
mmu04015 [list] [network] Rap1 signaling pathway (214 genes)
mmu04020 [list] [network] Calcium signaling pathway (240 genes)
mmu04072 [list] [network] Phospholipase D signaling pathway (149 genes)
mmu04144 [list] [network] Endocytosis (272 genes)
mmu04151 [list] [network] PI3K-Akt signaling pathway (359 genes)
mmu04510 [list] [network] Focal adhesion (201 genes)
mmu04540 [list] [network] Gap junction (86 genes)
mmu04630 [list] [network] JAK-STAT signaling pathway (168 genes)
mmu04810 [list] [network] Regulation of actin cytoskeleton (220 genes)
mmu05163 [list] [network] Human cytomegalovirus infection (256 genes)
mmu05200 [list] [network] Pathways in cancer (543 genes)
mmu05206 [list] [network] MicroRNAs in cancer (303 genes)
mmu05214 [list] [network] Glioma (74 genes)
mmu05215 [list] [network] Prostate cancer (99 genes)
mmu05218 [list] [network] Melanoma (72 genes)
mmu05230 [list] [network] Central carbon metabolism in cancer (69 genes)
mmu05231 [list] [network] Choline metabolism in cancer (98 genes)
Protein NP_001076785.1  NP_001334647.1  NP_001334648.1  NP_035188.2  XP_006504324.1  XP_006504325.1  XP_006504326.1 
BLAST NP_001076785.1  NP_001334647.1  NP_001334648.1  NP_035188.2  XP_006504324.1  XP_006504325.1  XP_006504326.1 
Orthologous [Ortholog page] PDGFRA (hsa)  Pdgfra (rno)  pdgfra (dre)  PDGFRA (gga)  PDGFRA (cfa)  PDGFRA (mcc)  PDGFRA (fca) 
Subcellular
localization
wolf
plas 3,  pero 3,  extr 2,  nucl 1,  E.R. 1  (predict for NP_001076785.1)
pero 3,  plas 3,  extr 2,  E.R. 1,  cysk_plas 1,  cyto_plas 1  (predict for NP_001334647.1)
pero 3,  plas 3,  extr 2,  E.R. 1,  cysk_plas 1,  cyto_plas 1  (predict for NP_001334648.1)
plas 3,  pero 3,  extr 2,  nucl 1,  E.R. 1  (predict for NP_035188.2)
plas 3,  pero 3,  extr 2,  nucl 1,  E.R. 1  (predict for XP_006504324.1)
plas 3,  pero 3,  extr 2,  nucl 1,  E.R. 1  (predict for XP_006504325.1)
plas 3,  pero 3,  extr 2,  nucl 1,  E.R. 1  (predict for XP_006504326.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04151 PI3K-Akt signaling pathway 5
mmu04510 Focal adhesion 4
mmu05200 Pathways in cancer 4
mmu05165 Human papillomavirus infection 3
mmu04015 Rap1 signaling pathway 3
Genes directly connected with Pdgfra on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
7.7 Pdgfrb platelet derived growth factor receptor, beta polypeptide [detail] 90 18596
7.3 Ddr2 discoidin domain receptor family, member 2 [detail] 3 18214
6.5 Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [detail] 0 64817
5.7 Lpar1 lysophosphatidic acid receptor 1 [detail] 1 14745
5.3 Bmper BMP-binding endothelial regulator [detail] 0 73230
5.0 Tgfbr3 transforming growth factor, beta receptor III [detail] 3 21814
4.8 Ccbe1 collagen and calcium binding EGF domains 1 [detail] 0 320924
4.8 Pcsk5 proprotein convertase subtilisin/kexin type 5 [detail] 0 18552
4.4 Cped1 cadherin-like and PC-esterase domain containing 1 [detail] 0 214642
Coexpressed
gene list		 [Coexpressed gene list for Pdgfra]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 18595      
Refseq ID (protein) NP_001076785.1 
NP_001334647.1 
NP_001334648.1 
NP_035188.2 
XP_006504324.1 
XP_006504325.1 
XP_006504326.1 


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