[←][→] mcc  HRAS Gene
functional annotation
Function   HRas proto-oncogene, GTPase  
GO BP
GO CC
GO MF
KEGG mcc01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (79 genes)
mcc01522 [list] [network] Endocrine resistance (98 genes)
mcc04010 [list] [network] MAPK signaling pathway (301 genes)
mcc04012 [list] [network] ErbB signaling pathway (85 genes)
mcc04014 [list] [network] Ras signaling pathway (250 genes)
mcc04015 [list] [network] Rap1 signaling pathway (229 genes)
mcc04062 [list] [network] Chemokine signaling pathway (200 genes)
mcc04068 [list] [network] FoxO signaling pathway (131 genes)
mcc04071 [list] [network] Sphingolipid signaling pathway (120 genes)
mcc04072 [list] [network] Phospholipase D signaling pathway (168 genes)
mcc04137 [list] [network] Mitophagy - animal (76 genes)
mcc04140 [list] [network] Autophagy - animal (147 genes)
mcc04144 [list] [network] Endocytosis (265 genes)
mcc04150 [list] [network] mTOR signaling pathway (155 genes)
mcc04151 [list] [network] PI3K-Akt signaling pathway (381 genes)
mcc04210 [list] [network] Apoptosis (150 genes)
mcc04211 [list] [network] Longevity regulating pathway (89 genes)
mcc04213 [list] [network] Longevity regulating pathway - multiple species (64 genes)
mcc04218 [list] [network] Cellular senescence (174 genes)
mcc04360 [list] [network] Axon guidance (182 genes)
mcc04370 [list] [network] VEGF signaling pathway (58 genes)
mcc04371 [list] [network] Apelin signaling pathway (142 genes)
mcc04510 [list] [network] Focal adhesion (205 genes)
mcc04540 [list] [network] Gap junction (94 genes)
mcc04550 [list] [network] Signaling pathways regulating pluripotency of stem cells (144 genes)
mcc04625 [list] [network] C-type lectin receptor signaling pathway (108 genes)
mcc04630 [list] [network] JAK-STAT signaling pathway (177 genes)
mcc04650 [list] [network] Natural killer cell mediated cytotoxicity (142 genes)
mcc04660 [list] [network] T cell receptor signaling pathway (107 genes)
mcc04662 [list] [network] B cell receptor signaling pathway (96 genes)
mcc04664 [list] [network] Fc epsilon RI signaling pathway (78 genes)
mcc04714 [list] [network] Thermogenesis (280 genes)
mcc04720 [list] [network] Long-term potentiation (70 genes)
mcc04722 [list] [network] Neurotrophin signaling pathway (122 genes)
mcc04725 [list] [network] Cholinergic synapse (114 genes)
mcc04726 [list] [network] Serotonergic synapse (118 genes)
mcc04730 [list] [network] Long-term depression (61 genes)
mcc04810 [list] [network] Regulation of actin cytoskeleton (221 genes)
mcc04910 [list] [network] Insulin signaling pathway (141 genes)
mcc04912 [list] [network] GnRH signaling pathway (97 genes)
mcc04915 [list] [network] Estrogen signaling pathway (144 genes)
mcc04916 [list] [network] Melanogenesis (103 genes)
mcc04917 [list] [network] Prolactin signaling pathway (70 genes)
mcc04919 [list] [network] Thyroid hormone signaling pathway (124 genes)
mcc04921 [list] [network] Oxytocin signaling pathway (163 genes)
mcc04926 [list] [network] Relaxin signaling pathway (133 genes)
mcc04929 [list] [network] GnRH secretion (64 genes)
mcc04933 [list] [network] AGE-RAGE signaling pathway in diabetic complications (102 genes)
mcc04935 [list] [network] Growth hormone synthesis, secretion and action (128 genes)
mcc05010 [list] [network] Alzheimer disease (441 genes)
mcc05022 [list] [network] Pathways of neurodegeneration - multiple diseases (540 genes)
mcc05034 [list] [network] Alcoholism (204 genes)
mcc05132 [list] [network] Salmonella infection (264 genes)
mcc05160 [list] [network] Hepatitis C (173 genes)
mcc05161 [list] [network] Hepatitis B (180 genes)
mcc05163 [list] [network] Human cytomegalovirus infection (257 genes)
mcc05165 [list] [network] Human papillomavirus infection (352 genes)
mcc05166 [list] [network] Human T-cell leukemia virus 1 infection (247 genes)
mcc05167 [list] [network] Kaposi sarcoma-associated herpesvirus infection (227 genes)
mcc05170 [list] [network] Human immunodeficiency virus 1 infection (247 genes)
mcc05200 [list] [network] Pathways in cancer (573 genes)
mcc05203 [list] [network] Viral carcinogenesis (223 genes)
mcc05205 [list] [network] Proteoglycans in cancer (211 genes)
mcc05206 [list] [network] MicroRNAs in cancer (293 genes)
mcc05207 [list] [network] Chemical carcinogenesis - receptor activation (215 genes)
mcc05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (272 genes)
mcc05210 [list] [network] Colorectal cancer (107 genes)
mcc05211 [list] [network] Renal cell carcinoma (72 genes)
mcc05213 [list] [network] Endometrial cancer (61 genes)
mcc05214 [list] [network] Glioma (79 genes)
mcc05215 [list] [network] Prostate cancer (97 genes)
mcc05216 [list] [network] Thyroid cancer (39 genes)
mcc05218 [list] [network] Melanoma (74 genes)
mcc05219 [list] [network] Bladder cancer (41 genes)
mcc05220 [list] [network] Chronic myeloid leukemia (80 genes)
mcc05221 [list] [network] Acute myeloid leukemia (69 genes)
mcc05223 [list] [network] Non-small cell lung cancer (75 genes)
mcc05224 [list] [network] Breast cancer (150 genes)
mcc05225 [list] [network] Hepatocellular carcinoma (177 genes)
mcc05226 [list] [network] Gastric cancer (153 genes)
mcc05230 [list] [network] Central carbon metabolism in cancer (76 genes)
mcc05231 [list] [network] Choline metabolism in cancer (107 genes)
mcc05235 [list] [network] PD-L1 expression and PD-1 checkpoint pathway in cancer (93 genes)
mcc05417 [list] [network] Lipid and atherosclerosis (237 genes)
Protein NP_001253350.1  XP_014968664.1  XP_028688383.1 
BLAST NP_001253350.1  XP_014968664.1  XP_028688383.1 
Orthologous [Ortholog page] HRAS (hsa)  KRAS (hsa)  NRAS (hsa)  RAP1A (hsa)  RAP1B (hsa)  Hras (mmu)  Kras (mmu)  Nras (mmu)  RRAS2 (hsa)  Kras (rno)  Nras (rno)  nras (dre)  Rap1 (dme)  Ras64B (dme)  Ras85D (dme)  Rras2 (mmu)  Rap1a (mmu)  Rap2a (rno)  Rap1b (rno)  ras-1 (cel)  rap-1 (cel)  let-60 (cel)  Rap1b (mmu)  Hras (rno)  Rap1a (rno)  rap1b (dre)  Rras2 (rno)  LOC367858 (rno)  zgc:55558 (dre)  HRAS (gga)  HRAS (cfa)  KRAS (cfa)  NRAS (cfa)  rap1ab (dre)  rap1aa (dre)  RAP1B (gga)  KRAS (gga)  RAP1A (gga)  NRAS (gga)  RRAS (gga)  kras (dre)  rras (dre)  RRAS2 (cfa)  RAP1A (cfa)  hrasa (dre)  rras2 (dre)  hrasb (dre)  RAP1B (cfa)  LOC693750 (mcc)  RRAS2 (mcc)  RAP1A (mcc)  KRAS (mcc)  NRAS (mcc)  RAP1B (mcc)  HRAS (fca)  KRAS (fca)  NRAS (fca)  RSR1 (sce)  RAS1 (sce)  RAS2 (sce)  RRAS2 (fca)  RAP1A (fca)  RAP1B (fca) 
Subcellular
localization
wolf
cyto 8,  cyto_nucl 5,  mito 2  (predict for NP_001253350.1)
cyto 5,  cyto_nucl 3,  mito 3,  nucl 1,  E.R._mito 1,  mito_pero 1  (predict for XP_014968664.1)
cyto 8,  cyto_nucl 5,  mito 2  (predict for XP_028688383.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05010 Alzheimer disease 6
mcc05022 Pathways of neurodegeneration - multiple diseases 6
mcc05208 Chemical carcinogenesis - reactive oxygen species 5
mcc05014 Amyotrophic lateral sclerosis 4
mcc05020 Prion disease 4
Genes directly connected with HRAS on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
6.0 STUB1 STIP1 homology and U-box containing protein 1 [detail] 697105
5.2 NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit [detail] 106995370
5.0 EDF1 endothelial differentiation related factor 1 [detail] 708611
Coexpressed
gene list		 [Coexpressed gene list for HRAS]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 698830      
Refseq ID (protein) NP_001253350.1 
XP_014968664.1 
XP_028688383.1 


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