[←][→] mmu  Gnai2 Gene
functional annotation
Function   guanine nucleotide binding protein (G protein), alpha inhibiting 2  
GO BP
GO:1903614 [list] [network] negative regulation of protein tyrosine phosphatase activity  (2 genes)  ISO  
GO:0140199 [list] [network] negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process  (3 genes)  ISO  
GO:0033864 [list] [network] positive regulation of NAD(P)H oxidase activity  (5 genes)  ISO  
GO:0001973 [list] [network] G protein-coupled adenosine receptor signaling pathway  (9 genes)  IBA ISO  
GO:0045955 [list] [network] negative regulation of calcium ion-dependent exocytosis  (10 genes)  ISO  
GO:0007213 [list] [network] G protein-coupled acetylcholine receptor signaling pathway  (13 genes)  IMP  
GO:0035810 [list] [network] positive regulation of urine volume  (13 genes)  ISO  
GO:0035815 [list] [network] positive regulation of renal sodium excretion  (15 genes)  ISO  
GO:0032930 [list] [network] positive regulation of superoxide anion generation  (24 genes)  ISO  
GO:0046628 [list] [network] positive regulation of insulin receptor signaling pathway  (25 genes)  ISO  
GO:0007214 [list] [network] gamma-aminobutyric acid signaling pathway  (30 genes)  IBA ISO  
GO:1904707 [list] [network] positive regulation of vascular associated smooth muscle cell proliferation  (34 genes)  ISO  
GO:0007193 [list] [network] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (67 genes)  IBA IMP ISA  
GO:0050805 [list] [network] negative regulation of synaptic transmission  (70 genes)  ISO  
GO:2000179 [list] [network] positive regulation of neural precursor cell proliferation  (72 genes)  ISO  
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway  (128 genes)  ISO  
GO:0008016 [list] [network] regulation of heart contraction  (191 genes)  IMP  
GO:0007188 [list] [network] adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (203 genes)  IBA  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (228 genes)  ISO  
GO:2001234 [list] [network] negative regulation of apoptotic signaling pathway  (239 genes)  ISO  
GO:0051924 [list] [network] regulation of calcium ion transport  (287 genes)  ISO  
GO:0051301 [list] [network] cell division  (494 genes)  ISO  
GO:0030335 [list] [network] positive regulation of cell migration  (567 genes)  ISO  
GO:0008283 [list] [network] cell population proliferation  (578 genes)  IPI  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (1011 genes)  ISO  
GO:0007049 [list] [network] cell cycle  (1198 genes)  IEA  
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway  (1829 genes)  ISO  
GO:0007165 [list] [network] signal transduction  (4968 genes)  IEA  
GO CC
GO:0005834 [list] [network] heterotrimeric G-protein complex  (35 genes)  IBA  
GO:0030496 [list] [network] midbody  (183 genes)  ISO  
GO:0045121 [list] [network] membrane raft  (390 genes)  ISO  
GO:0005813 [list] [network] centrosome  (622 genes)  ISO  
GO:0030425 [list] [network] dendrite  (740 genes)  IDA  
GO:0044297 [list] [network] cell body  (814 genes)  IDA  
GO:0005856 [list] [network] cytoskeleton  (2248 genes)  IEA  
GO:0005654 [list] [network] nucleoplasm  (3580 genes)  ISO  
GO:0005829 [list] [network] cytosol  (3785 genes)  ISO  
GO:0005886 [list] [network] plasma membrane  (5442 genes)  ISO TAS  
GO:0005634 [list] [network] nucleus  (7226 genes)  ISO  
GO:0016020 [list] [network] membrane  (9571 genes)  ISO  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  ISO  
GO MF
GO:0031683 [list] [network] G-protein beta/gamma-subunit complex binding  (24 genes)  IBA  
GO:0003924 [list] [network] GTPase activity  (294 genes)  IBA  
GO:0001664 [list] [network] G protein-coupled receptor binding  (318 genes)  IBA  
GO:0005525 [list] [network] GTP binding  (358 genes)  ISA  
GO:0019001 [list] [network] guanyl nucleotide binding  (381 genes)  IEA  
GO:0000166 [list] [network] nucleotide binding  (2052 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (3573 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04015 [list] [network] Rap1 signaling pathway (214 genes)
mmu04022 [list] [network] cGMP-PKG signaling pathway (173 genes)
mmu04024 [list] [network] cAMP signaling pathway (220 genes)
mmu04062 [list] [network] Chemokine signaling pathway (192 genes)
mmu04071 [list] [network] Sphingolipid signaling pathway (124 genes)
mmu04261 [list] [network] Adrenergic signaling in cardiomyocytes (152 genes)
mmu04360 [list] [network] Axon guidance (181 genes)
mmu04371 [list] [network] Apelin signaling pathway (137 genes)
mmu04540 [list] [network] Gap junction (86 genes)
mmu04611 [list] [network] Platelet activation (124 genes)
mmu04670 [list] [network] Leukocyte transendothelial migration (118 genes)
mmu04713 [list] [network] Circadian entrainment (98 genes)
mmu04723 [list] [network] Retrograde endocannabinoid signaling (148 genes)
mmu04724 [list] [network] Glutamatergic synapse (113 genes)
mmu04725 [list] [network] Cholinergic synapse (112 genes)
mmu04726 [list] [network] Serotonergic synapse (131 genes)
mmu04727 [list] [network] GABAergic synapse (89 genes)
mmu04728 [list] [network] Dopaminergic synapse (135 genes)
mmu04730 [list] [network] Long-term depression (60 genes)
mmu04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes)
mmu04915 [list] [network] Estrogen signaling pathway (134 genes)
mmu04916 [list] [network] Melanogenesis (100 genes)
mmu04921 [list] [network] Oxytocin signaling pathway (153 genes)
mmu04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes)
mmu04924 [list] [network] Renin secretion (76 genes)
mmu04926 [list] [network] Relaxin signaling pathway (129 genes)
mmu04928 [list] [network] Parathyroid hormone synthesis, secretion and action (108 genes)
mmu04934 [list] [network] Cushing syndrome (162 genes)
mmu04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes)
mmu04971 [list] [network] Gastric acid secretion (75 genes)
mmu05012 [list] [network] Parkinson disease (264 genes)
mmu05030 [list] [network] Cocaine addiction (48 genes)
mmu05032 [list] [network] Morphine addiction (91 genes)
mmu05034 [list] [network] Alcoholism (205 genes)
mmu05133 [list] [network] Pertussis (77 genes)
mmu05142 [list] [network] Chagas disease (103 genes)
mmu05145 [list] [network] Toxoplasmosis (110 genes)
mmu05163 [list] [network] Human cytomegalovirus infection (256 genes)
mmu05170 [list] [network] Human immunodeficiency virus 1 infection (240 genes)
mmu05200 [list] [network] Pathways in cancer (543 genes)
mmu05207 [list] [network] Chemical carcinogenesis - receptor activation (225 genes)
Protein NP_032164.2  XP_006511700.1 
BLAST NP_032164.2  XP_006511700.1 
Orthologous [Ortholog page] GNA11 (hsa)  GNAI1 (hsa)  GNAI2 (hsa)  GNAI3 (hsa)  GNAO1 (hsa)  GNAQ (hsa)  GNAT1 (hsa)  GNAT2 (hsa)  GNAZ (hsa)  GNA14 (hsa)  Gna11 (mmu)  Gna14 (mmu)  Gnai1 (mmu)  Gnai3 (mmu)  Gnao1 (mmu)  Gnaq (mmu)  Gnat1 (mmu)  Gnat2 (mmu)  Gnaz (mmu)  Gnai3 (rno)  Gnai1 (rno)  Gnaz (rno)  Galphao (dme)  Galphaq (dme)  CG17760 (dme)  Galphai (dme)  Gnao1 (rno)  Gna11 (rno)  Gnai2 (rno)  Gnaq (rno)  gnat1 (dre)  gnat2 (dre)  gpa-16 (cel)  egl-30 (cel)  goa-1 (cel)  gpa-15 (cel)  gpa-4 (cel)  gpa-7 (cel)  gpa-2 (cel)  gpa-3 (cel)  gpa-1 (cel)  gpa-8 (cel)  odr-3 (cel)  Gnat3 (mmu)  CG30054 (dme)  Gnat3 (rno)  Gna14 (rno)  gnaia (dre)  gnai2b (dre)  gnai2a (dre)  GNAT3 (hsa)  Gnat1 (rno)  Gnat2 (rno)  GNA11 (gga)  GNAI3 (gga)  gnao1a (dre)  gnao1b (dre)  gnai1 (dre)  GNAT2 (gga)  GNAT1 (gga)  GNAI2 (gga)  GNAI1 (gga)  GNAT1 (cfa)  GNA11 (cfa)  GNAQ (cfa)  GNAO1 (gga)  GNAQ (gga)  GNAT3 (gga)  GNA14 (gga)  GNAI2 (cfa)  gna15.1 (dre)  gna14 (dre)  GNAI1 (cfa)  GNA14 (cfa)  GNAT2 (cfa)  GNAT3 (cfa)  gna11b (dre)  gna14a (dre)  gna11a (dre)  gnaz (dre)  gnaq (dre)  gnav1 (dre)  GNAO1 (mcc)  GNAZ (cfa)  GNAO1 (cfa)  GNAI3 (cfa)  GNAI3 (mcc)  GNAT2 (mcc)  GNAI2 (mcc)  GNAT1 (mcc)  GNA14 (mcc)  GNAQ (mcc)  GNAZ (mcc)  GNAT3 (mcc)  GNAI1 (mcc)  GNA11 (mcc)  GNAZ (gga)  GPA1 (sce)  GPA2 (sce)  gnai3 (dre)  gna15.2 (dre)  GNA11 (fca)  GNAI2 (fca)  GNAT1 (fca)  GNAI1 (fca)  GNAT3 (fca)  GNA14 (fca)  GNAQ (fca)  GNAI3 (fca)  GNAT2 (fca)  GNAZ (fca)  GNAO1 (fca) 
Subcellular
localization
wolf
cyto 7,  mito_pero 1,  mito 1,  plas 1,  pero 1,  golg 1  (predict for NP_032164.2)
cyto 7,  mito_pero 1,  mito 1,  plas 1,  pero 1,  golg 1  (predict for XP_006511700.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04015 Rap1 signaling pathway 6
mmu05170 Human immunodeficiency virus 1 infection 6
mmu04810 Regulation of actin cytoskeleton 6
mmu05132 Salmonella infection 6
mmu04921 Oxytocin signaling pathway 5
Genes directly connected with Gnai2 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
7.8 Gnb2 guanine nucleotide binding protein (G protein), beta 2 [detail] 4 14693
7.5 Cfl1 cofilin 1, non-muscle [detail] 1 12631
7.3 Arhgdia Rho GDP dissociation inhibitor (GDI) alpha [detail] 0 192662
7.1 Mapk3 mitogen-activated protein kinase 3 [detail] 3 26417
6.7 Gltp glycolipid transfer protein [detail] 0 56356
6.2 Macroh2a1 macroH2A.1 histone [detail] 0 26914
5.9 Flot2 flotillin 2 [detail] 0 14252
4.7 Irak1 interleukin-1 receptor-associated kinase 1 [detail] 0 16179
Coexpressed
gene list		 [Coexpressed gene list for Gnai2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 14678      
Refseq ID (protein) NP_032164.2 
XP_006511700.1 


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