[←][→] hsa  PRKACB Gene
functional annotation
Function   protein kinase cAMP-activated catalytic subunit beta  
GO BP
GO:0097338 [list] [network] response to clozapine  (3 genes)  IEA  
GO:1901621 [list] [network] negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning  (5 genes)  IEA  
GO:0034380 [list] [network] high-density lipoprotein particle assembly  (13 genes)  TAS  
GO:0010737 [list] [network] protein kinase A signaling  (14 genes)  IBA  
GO:0034199 [list] [network] activation of protein kinase A activity  (18 genes)  TAS  
GO:0051447 [list] [network] negative regulation of meiotic cell cycle  (18 genes)  IEA  
GO:0071377 [list] [network] cellular response to glucagon stimulus  (27 genes)  TAS  
GO:0003091 [list] [network] renal water homeostasis  (36 genes)  TAS  
GO:0070613 [list] [network] regulation of protein processing  (65 genes)  IEA  
GO:0001843 [list] [network] neural tube closure  (88 genes)  IEA  
GO:0002223 [list] [network] stimulatory C-type lectin receptor signaling pathway  (115 genes)  TAS  
GO:0002862 [list] [network] negative regulation of inflammatory response to antigenic stimulus  (208 genes)  TAS  
GO:0007188 [list] [network] adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (219 genes)  TAS  
GO:0007596 [list] [network] blood coagulation  (308 genes)  TAS  
GO:0007268 [list] [network] chemical synaptic transmission  (415 genes)  TAS  
GO:0002250 [list] [network] adaptive immune response  (634 genes)  TAS  
GO:0006468 [list] [network] protein phosphorylation  (682 genes)  IDA  
GO:0007165 [list] [network] signal transduction  (5169 genes)  TAS  
GO CC
GO:0005952 [list] [network] cAMP-dependent protein kinase complex  (10 genes)  TAS  
GO:0097546 [list] [network] ciliary base  (39 genes)  TAS  
GO:0005813 [list] [network] centrosome  (613 genes)  IDA  
GO:0048471 [list] [network] perinuclear region of cytoplasm  (733 genes)  IEA  
GO:0045202 [list] [network] synapse  (1341 genes)  IEA  
GO:0070062 [list] [network] extracellular exosome  (2212 genes)  HDA  
GO:0005654 [list] [network] nucleoplasm  (4086 genes)  TAS  
GO:0005829 [list] [network] cytosol  (5345 genes)  TAS  
GO:0005886 [list] [network] plasma membrane  (5772 genes)  IEA  
GO:0005634 [list] [network] nucleus  (8115 genes)  IBA  
GO MF
GO:0004679 [list] [network] AMP-activated protein kinase activity  (8 genes)  IEA  
GO:0004691 [list] [network] cAMP-dependent protein kinase activity  (8 genes)  IDA  
GO:0000287 [list] [network] magnesium ion binding  (217 genes)  IDA  
GO:0031625 [list] [network] ubiquitin protein ligase binding  (297 genes)  IDA  
GO:0106310 [list] [network] protein serine kinase activity  (360 genes)  IEA  
GO:0106311 [list] [network] protein threonine kinase activity  (360 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (1474 genes)  IDA  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa01522 [list] [network] Endocrine resistance (98 genes)
hsa04010 [list] [network] MAPK signaling pathway (294 genes)
hsa04014 [list] [network] Ras signaling pathway (232 genes)
hsa04020 [list] [network] Calcium signaling pathway (240 genes)
hsa04024 [list] [network] cAMP signaling pathway (221 genes)
hsa04062 [list] [network] Chemokine signaling pathway (192 genes)
hsa04114 [list] [network] Oocyte meiosis (131 genes)
hsa04140 [list] [network] Autophagy - animal (141 genes)
hsa04211 [list] [network] Longevity regulating pathway (89 genes)
hsa04213 [list] [network] Longevity regulating pathway - multiple species (62 genes)
hsa04261 [list] [network] Adrenergic signaling in cardiomyocytes (150 genes)
hsa04270 [list] [network] Vascular smooth muscle contraction (134 genes)
hsa04310 [list] [network] Wnt signaling pathway (167 genes)
hsa04340 [list] [network] Hedgehog signaling pathway (56 genes)
hsa04371 [list] [network] Apelin signaling pathway (139 genes)
hsa04530 [list] [network] Tight junction (169 genes)
hsa04540 [list] [network] Gap junction (88 genes)
hsa04611 [list] [network] Platelet activation (124 genes)
hsa04713 [list] [network] Circadian entrainment (97 genes)
hsa04714 [list] [network] Thermogenesis (232 genes)
hsa04720 [list] [network] Long-term potentiation (67 genes)
hsa04723 [list] [network] Retrograde endocannabinoid signaling (148 genes)
hsa04724 [list] [network] Glutamatergic synapse (114 genes)
hsa04725 [list] [network] Cholinergic synapse (113 genes)
hsa04726 [list] [network] Serotonergic synapse (115 genes)
hsa04727 [list] [network] GABAergic synapse (89 genes)
hsa04728 [list] [network] Dopaminergic synapse (132 genes)
hsa04740 [list] [network] Olfactory transduction (441 genes)
hsa04742 [list] [network] Taste transduction (86 genes)
hsa04750 [list] [network] Inflammatory mediator regulation of TRP channels (98 genes)
hsa04910 [list] [network] Insulin signaling pathway (137 genes)
hsa04911 [list] [network] Insulin secretion (86 genes)
hsa04912 [list] [network] GnRH signaling pathway (93 genes)
hsa04913 [list] [network] Ovarian steroidogenesis (51 genes)
hsa04914 [list] [network] Progesterone-mediated oocyte maturation (102 genes)
hsa04915 [list] [network] Estrogen signaling pathway (138 genes)
hsa04916 [list] [network] Melanogenesis (101 genes)
hsa04918 [list] [network] Thyroid hormone synthesis (75 genes)
hsa04919 [list] [network] Thyroid hormone signaling pathway (121 genes)
hsa04921 [list] [network] Oxytocin signaling pathway (154 genes)
hsa04922 [list] [network] Glucagon signaling pathway (107 genes)
hsa04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes)
hsa04924 [list] [network] Renin secretion (69 genes)
hsa04925 [list] [network] Aldosterone synthesis and secretion (98 genes)
hsa04926 [list] [network] Relaxin signaling pathway (129 genes)
hsa04927 [list] [network] Cortisol synthesis and secretion (65 genes)
hsa04928 [list] [network] Parathyroid hormone synthesis, secretion and action (106 genes)
hsa04934 [list] [network] Cushing syndrome (155 genes)
hsa04935 [list] [network] Growth hormone synthesis, secretion and action (119 genes)
hsa04961 [list] [network] Endocrine and other factor-regulated calcium reabsorption (53 genes)
hsa04962 [list] [network] Vasopressin-regulated water reabsorption (44 genes)
hsa04970 [list] [network] Salivary secretion (93 genes)
hsa04971 [list] [network] Gastric acid secretion (76 genes)
hsa04976 [list] [network] Bile secretion (89 genes)
hsa05012 [list] [network] Parkinson disease (266 genes)
hsa05020 [list] [network] Prion disease (273 genes)
hsa05030 [list] [network] Cocaine addiction (49 genes)
hsa05031 [list] [network] Amphetamine addiction (69 genes)
hsa05032 [list] [network] Morphine addiction (91 genes)
hsa05034 [list] [network] Alcoholism (187 genes)
hsa05110 [list] [network] Vibrio cholerae infection (50 genes)
hsa05146 [list] [network] Amoebiasis (102 genes)
hsa05163 [list] [network] Human cytomegalovirus infection (225 genes)
hsa05165 [list] [network] Human papillomavirus infection (331 genes)
hsa05166 [list] [network] Human T-cell leukemia virus 1 infection (222 genes)
hsa05200 [list] [network] Pathways in cancer (531 genes)
hsa05203 [list] [network] Viral carcinogenesis (204 genes)
hsa05205 [list] [network] Proteoglycans in cancer (205 genes)
hsa05207 [list] [network] Chemical carcinogenesis - receptor activation (212 genes)
hsa05414 [list] [network] Dilated cardiomyopathy (96 genes)
Protein NP_001229786.1  NP_001229787.1  NP_001229788.1  NP_001229789.1  NP_001229790.1  NP_001229791.1  NP_001287844.1  NP_001287845.1  NP_001287846.1  NP_001362489.1  NP_001362490.1  NP_001362491.1  NP_001362492.1  NP_001362493.1  NP_001362494.1  NP_001362498.1  NP_001362500.1  NP_001362501.1  NP_001362502.1  NP_001362503.1  NP_001362504.1  NP_001362505.1  NP_001362506.1  NP_001362507.1  NP_001362508.1  NP_001362509.1  NP_001362510.1  NP_002722.1  NP_891993.1  NP_997461.1  XP_005271077.1  XP_016857200.1  XP_016857205.1  XP_016857206.1 
BLAST NP_001229786.1  NP_001229787.1  NP_001229788.1  NP_001229789.1  NP_001229790.1  NP_001229791.1  NP_001287844.1  NP_001287845.1  NP_001287846.1  NP_001362489.1  NP_001362490.1  NP_001362491.1  NP_001362492.1  NP_001362493.1  NP_001362494.1  NP_001362498.1  NP_001362500.1  NP_001362501.1  NP_001362502.1  NP_001362503.1  NP_001362504.1  NP_001362505.1  NP_001362506.1  NP_001362507.1  NP_001362508.1  NP_001362509.1  NP_001362510.1  NP_002722.1  NP_891993.1  NP_997461.1  XP_005271077.1  XP_016857200.1  XP_016857205.1  XP_016857206.1 
Orthologous [Ortholog page] PRKACA (hsa)  PRKACG (hsa)  PRKX (hsa)  Prkaca (mmu)  Prkacb (mmu)  Prkx (mmu)  Prkaca (rno)  Pka-C1 (dme)  Pka-C3 (dme)  CG12069 (dme)  Pka-C2 (dme)  F47F2.1 (cel)  Prkacb (rno)  prkacba (dre)  PRKACA (cfa)  PRKX (gga)  PRKACB (gga)  prkacab (dre)  PRKACB (cfa)  Prkx (rno)  prkx (dre)  prkacbb (dre)  prkacaa (dre)  PRKX (cfa)  PRKACG (mcc)  PRKACB (mcc)  PRKACA (mcc)  TPK1 (sce)  TPK3 (sce)  TPK2 (sce)  rpl35a (spo)  rpl35b (spo)  kin-1 (cel)  PRKX (mcc)  PRKACA (fca)  PRKACB (fca)  LOC106992273 (mcc)  PRKX (fca) 
Subcellular
localization
wolf
cyto 7,  cyto_nucl 4,  nucl 1,  pero 1  (predict for NP_001229786.1)
cyto 8,  cyto_nucl 5,  cyto_pero 4,  nucl 1  (predict for NP_001229787.1)
cyto 7,  nucl 2,  pero 1  (predict for NP_001229788.1)
cyto 6,  nucl 2,  pero 1  (predict for NP_001229789.1)
cyto 5,  cyto_nucl 3,  mito 2,  nucl 1,  mito_pero 1  (predict for NP_001229790.1)
cyto 7,  cyto_nucl 4,  mito 2  (predict for NP_001229791.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001287844.1)
cyto 5,  cyto_nucl 4,  mito 2,  nucl 2  (predict for NP_001287845.1)
cyto 8,  cyto_nucl 5,  cyto_pero 4  (predict for NP_001287846.1)
cyto 6,  mito 2,  pero 1,  mito_nucl 1  (predict for NP_001362489.1)
cyto 6,  cyto_nucl 5,  cyto_pero 4,  cyto_plas 3,  nucl 2  (predict for NP_001362490.1)
cyto 4,  mito 4,  cyto_pero 3,  pero 1  (predict for NP_001362491.1)
cyto 4,  mito 4,  nucl 2  (predict for NP_001362492.1)
cyto 6,  cyto_nucl 5,  cyto_pero 4,  cyto_plas 3,  nucl 2  (predict for NP_001362493.1)
cyto 6,  cyto_nucl 4,  pero 1,  extr 1,  nucl 1,  mito_pero 1  (predict for NP_001362494.1)
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 2  (predict for NP_001362498.1)
cyto 6,  cyto_nucl 4,  nucl 2,  mito 1  (predict for NP_001362500.1)
cyto 6,  cyto_nucl 5,  nucl 2,  pero 1  (predict for NP_001362501.1)
cyto 5,  cyto_nucl 3,  mito 2,  nucl 2  (predict for NP_001362502.1)
cyto 8,  cyto_nucl 5,  cyto_plas 4,  nucl 1  (predict for NP_001362503.1)
cyto 5,  cyto_nucl 3,  mito 2,  nucl 2  (predict for NP_001362504.1)
mito 4,  cyto 3,  cyto_nucl 3,  extr 1  (predict for NP_001362505.1)
cyto 8,  cyto_nucl 5,  cyto_plas 4,  nucl 1  (predict for NP_001362506.1)
cyto 8,  cyto_nucl 5,  cyto_pero 4  (predict for NP_001362507.1)
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 1,  extr 1  (predict for NP_001362508.1)
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 1,  extr 1  (predict for NP_001362509.1)
cyto 6,  cyto_nucl 4,  cyto_plas 3,  nucl 2  (predict for NP_001362510.1)
cyto_mito 4,  cyto 4,  mito 4,  cyto_nucl 3  (predict for NP_002722.1)
cyto 7,  cyto_nucl 4,  nucl 1,  mito 1  (predict for NP_891993.1)
mito 4,  cyto 3,  cyto_nucl 3,  extr 1  (predict for NP_997461.1)
cyto 5,  cyto_nucl 4,  mito 2,  nucl 2  (predict for XP_005271077.1)
cyto 6,  cyto_nucl 5,  nucl 2,  pero 1  (predict for XP_016857200.1)
cyto 4,  mito 4,  nucl 2,  E.R._mito 2,  mito_pero 2  (predict for XP_016857205.1)
cyto 7,  cyto_nucl 6,  cyto_plas 4,  cyto_pero 4,  nucl 2  (predict for XP_016857206.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04530 Tight junction 2
hsa04114 Oocyte meiosis 2
hsa04014 Ras signaling pathway 2
hsa04062 Chemokine signaling pathway 2
hsa04371 Apelin signaling pathway 2
Genes directly connected with PRKACB on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
7.2 SAMD13 sterile alpha motif domain containing 13 [detail] 1 148418
5.9 MAPRE2 microtubule associated protein RP/EB family member 2 [detail] 0 10982
5.7 TTLL7 tubulin tyrosine ligase like 7 [detail] 0 79739
5.0 SSX2IP SSX family member 2 interacting protein [detail] 0 117178
Coexpressed
gene list		 [Coexpressed gene list for PRKACB]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 5567      
Refseq ID (protein) NP_001229786.1 
NP_001229787.1 
NP_001229788.1 
NP_001229789.1 
NP_001229790.1 
NP_001229791.1 
NP_001287844.1 
NP_001287845.1 
NP_001287846.1 
NP_001362489.1 
NP_001362490.1 
NP_001362491.1 
NP_001362492.1 
NP_001362493.1 
NP_001362494.1 
NP_001362498.1 
NP_001362500.1 
NP_001362501.1 
NP_001362502.1 
NP_001362503.1 
NP_001362504.1 
NP_001362505.1 
NP_001362506.1 
NP_001362507.1 
NP_001362508.1 
NP_001362509.1 
NP_001362510.1 
NP_002722.1 
NP_891993.1 
NP_997461.1 
XP_005271077.1 
XP_016857200.1 
XP_016857205.1 
XP_016857206.1 


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