[←][→] mcc  GRB2 Gene
functional annotation
Function   growth factor receptor bound protein 2  
GO BP
GO CC
GO MF
KEGG mcc01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (79 genes)
mcc01522 [list] [network] Endocrine resistance (98 genes)
mcc04010 [list] [network] MAPK signaling pathway (301 genes)
mcc04012 [list] [network] ErbB signaling pathway (85 genes)
mcc04014 [list] [network] Ras signaling pathway (250 genes)
mcc04062 [list] [network] Chemokine signaling pathway (200 genes)
mcc04068 [list] [network] FoxO signaling pathway (131 genes)
mcc04072 [list] [network] Phospholipase D signaling pathway (168 genes)
mcc04150 [list] [network] mTOR signaling pathway (155 genes)
mcc04151 [list] [network] PI3K-Akt signaling pathway (381 genes)
mcc04380 [list] [network] Osteoclast differentiation (131 genes)
mcc04510 [list] [network] Focal adhesion (205 genes)
mcc04540 [list] [network] Gap junction (94 genes)
mcc04550 [list] [network] Signaling pathways regulating pluripotency of stem cells (144 genes)
mcc04630 [list] [network] JAK-STAT signaling pathway (177 genes)
mcc04650 [list] [network] Natural killer cell mediated cytotoxicity (142 genes)
mcc04660 [list] [network] T cell receptor signaling pathway (107 genes)
mcc04662 [list] [network] B cell receptor signaling pathway (96 genes)
mcc04664 [list] [network] Fc epsilon RI signaling pathway (78 genes)
mcc04714 [list] [network] Thermogenesis (280 genes)
mcc04722 [list] [network] Neurotrophin signaling pathway (122 genes)
mcc04910 [list] [network] Insulin signaling pathway (141 genes)
mcc04912 [list] [network] GnRH signaling pathway (97 genes)
mcc04915 [list] [network] Estrogen signaling pathway (144 genes)
mcc04917 [list] [network] Prolactin signaling pathway (70 genes)
mcc04926 [list] [network] Relaxin signaling pathway (133 genes)
mcc04935 [list] [network] Growth hormone synthesis, secretion and action (128 genes)
mcc05034 [list] [network] Alcoholism (204 genes)
mcc05160 [list] [network] Hepatitis C (173 genes)
mcc05161 [list] [network] Hepatitis B (180 genes)
mcc05163 [list] [network] Human cytomegalovirus infection (257 genes)
mcc05165 [list] [network] Human papillomavirus infection (352 genes)
mcc05200 [list] [network] Pathways in cancer (573 genes)
mcc05203 [list] [network] Viral carcinogenesis (223 genes)
mcc05205 [list] [network] Proteoglycans in cancer (211 genes)
mcc05206 [list] [network] MicroRNAs in cancer (293 genes)
mcc05207 [list] [network] Chemical carcinogenesis - receptor activation (215 genes)
mcc05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (272 genes)
mcc05210 [list] [network] Colorectal cancer (107 genes)
mcc05211 [list] [network] Renal cell carcinoma (72 genes)
mcc05213 [list] [network] Endometrial cancer (61 genes)
mcc05214 [list] [network] Glioma (79 genes)
mcc05215 [list] [network] Prostate cancer (97 genes)
mcc05220 [list] [network] Chronic myeloid leukemia (80 genes)
mcc05221 [list] [network] Acute myeloid leukemia (69 genes)
mcc05223 [list] [network] Non-small cell lung cancer (75 genes)
mcc05224 [list] [network] Breast cancer (150 genes)
mcc05225 [list] [network] Hepatocellular carcinoma (177 genes)
mcc05226 [list] [network] Gastric cancer (153 genes)
mcc05231 [list] [network] Choline metabolism in cancer (107 genes)
Protein XP_014975798.1  XP_028692620.1  XP_028692621.1 
BLAST XP_014975798.1  XP_028692620.1  XP_028692621.1 
Orthologous [Ortholog page] GRB2 (hsa)  GRAP2 (hsa)  GRAP (hsa)  Grb2 (mmu)  Grap2 (mmu)  drk (dme)  Grap (mmu)  Grb2 (rno)  sem-5 (cel)  Grap (rno)  Grap2 (rno)  GRB2 (gga)  grap2b (dre)  GRAPL (hsa)  grb2b (dre)  GRAPL (gga)  GRAP2 (cfa)  GRB2 (cfa)  LOC489534 (cfa)  grb2a (dre)  grap2a (dre)  grapa (dre)  grapb (dre)  GRAP (mcc)  GRAP2 (mcc)  GRAP2 (gga)  LSB1 (sce)  PIN3 (sce)  sla2a (dre)  GRAP2 (fca)  GRAP (fca)  GRB2 (fca) 
Subcellular
localization
wolf
cyto 9,  cyto_nucl 5  (predict for XP_014975798.1)
cyto 9,  cyto_nucl 5  (predict for XP_028692620.1)
cyto 9,  cyto_nucl 5  (predict for XP_028692621.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05163 Human cytomegalovirus infection 6
mcc05200 Pathways in cancer 6
mcc04014 Ras signaling pathway 5
mcc04024 cAMP signaling pathway 5
mcc04062 Chemokine signaling pathway 5
Genes directly connected with GRB2 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
7.8 GNAI2 G protein subunit alpha i2 [detail] 703780
7.1 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta [detail] 717788
5.7 CNDP2 carnosine dipeptidase 2 [detail] 695080
5.7 ABHD12 abhydrolase domain containing 12, lysophospholipase [detail] 705915
5.3 CRLF3 cytokine receptor like factor 3 [detail] 713495
5.0 SMAP2 small ArfGAP2 [detail] 694502
Coexpressed
gene list		 [Coexpressed gene list for GRB2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 702041      
Refseq ID (protein) XP_014975798.1 
XP_028692620.1 
XP_028692621.1 


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