[←][→] rno  Pdgfrb Gene
functional annotation
Function   platelet derived growth factor receptor beta  
GO BP
GO:0035789 [list] [network] metanephric mesenchymal cell migration  (1 genes)  IDA  
GO:0060981 [list] [network] cell migration involved in coronary angiogenesis  (1 genes)  ISO ISS  
GO:0106096 [list] [network] response to ceramide  (1 genes)  ISO  
GO:0071670 [list] [network] smooth muscle cell chemotaxis  (2 genes)  ISO  
GO:0072262 [list] [network] metanephric glomerular mesangial cell proliferation involved in metanephros development  (2 genes)  ISO ISS  
GO:0035441 [list] [network] cell migration involved in vasculogenesis  (3 genes)  ISO ISS  
GO:0035793 [list] [network] positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway  (3 genes)  ISO ISS  
GO:0038091 [list] [network] positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway  (3 genes)  ISO  
GO:0072223 [list] [network] metanephric glomerular mesangium development  (3 genes)  ISO  
GO:0072275 [list] [network] metanephric glomerulus morphogenesis  (3 genes)  IEP  
GO:0072277 [list] [network] metanephric glomerular capillary formation  (3 genes)  ISO ISS  
GO:0072278 [list] [network] metanephric comma-shaped body morphogenesis  (4 genes)  IEP  
GO:0072284 [list] [network] metanephric S-shaped body morphogenesis  (5 genes)  IEP  
GO:0035791 [list] [network] platelet-derived growth factor receptor-beta signaling pathway  (7 genes)  ISO  
GO:0060437 [list] [network] lung growth  (8 genes)  IMP  
GO:2000491 [list] [network] positive regulation of hepatic stellate cell activation  (8 genes)  IMP  
GO:0072075 [list] [network] metanephric mesenchyme development  (11 genes)  IEP  
GO:0097178 [list] [network] ruffle assembly  (16 genes)  ISO  
GO:0055003 [list] [network] cardiac myofibril assembly  (17 genes)  ISO ISS  
GO:0032516 [list] [network] positive regulation of phosphoprotein phosphatase activity  (21 genes)  ISO  
GO:0061298 [list] [network] retina vasculature development in camera-type eye  (25 genes)  ISO ISS  
GO:0090280 [list] [network] positive regulation of calcium ion import  (27 genes)  ISO ISS  
GO:0048745 [list] [network] smooth muscle tissue development  (30 genes)  ISO  
GO:0010863 [list] [network] positive regulation of phospholipase C activity  (31 genes)  ISO ISS  
GO:0043552 [list] [network] positive regulation of phosphatidylinositol 3-kinase activity  (31 genes)  ISO ISS  
GO:0032967 [list] [network] positive regulation of collagen biosynthetic process  (33 genes)  IMP  
GO:0035909 [list] [network] aorta morphogenesis  (33 genes)  ISO  
GO:0035025 [list] [network] positive regulation of Rho protein signal transduction  (34 genes)  IMP  
GO:0036120 [list] [network] cellular response to platelet-derived growth factor stimulus  (35 genes)  IEA  
GO:0006024 [list] [network] glycosaminoglycan biosynthetic process  (38 genes)  IMP  
GO:0048008 [list] [network] platelet-derived growth factor receptor signaling pathway  (39 genes)  ISO  
GO:0030325 [list] [network] adrenal gland development  (42 genes)  ISO  
GO:0034405 [list] [network] response to fluid shear stress  (46 genes)  IEP  
GO:0045840 [list] [network] positive regulation of mitotic nuclear division  (48 genes)  ISO ISS  
GO:0055093 [list] [network] response to hyperoxia  (52 genes)  IEP  
GO:0014911 [list] [network] positive regulation of smooth muscle cell migration  (68 genes)  IBA ISO ISS  
GO:0048146 [list] [network] positive regulation of fibroblast proliferation  (75 genes)  IMP  
GO:0048015 [list] [network] phosphatidylinositol-mediated signaling  (77 genes)  ISO ISS  
GO:2000573 [list] [network] positive regulation of DNA biosynthetic process  (77 genes)  ISO ISS  
GO:2000379 [list] [network] positive regulation of reactive oxygen species metabolic process  (80 genes)  ISO ISS  
GO:0014068 [list] [network] positive regulation of phosphatidylinositol 3-kinase signaling  (81 genes)  ISO ISS  
GO:0043406 [list] [network] positive regulation of MAP kinase activity  (101 genes)  ISO ISS  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (102 genes)  ISO  
GO:0048661 [list] [network] positive regulation of smooth muscle cell proliferation  (115 genes)  ISO ISS  
GO:0043627 [list] [network] response to estrogen  (137 genes)  IEP  
GO:0046488 [list] [network] phosphatidylinositol metabolic process  (144 genes)  ISO ISS  
GO:0018108 [list] [network] peptidyl-tyrosine phosphorylation  (149 genes)  ISO ISS  
GO:0032526 [list] [network] response to retinoic acid  (152 genes)  IEP  
GO:0050921 [list] [network] positive regulation of chemotaxis  (160 genes)  ISO ISS  
GO:0042542 [list] [network] response to hydrogen peroxide  (171 genes)  IEP  
GO:0008584 [list] [network] male gonad development  (194 genes)  IEP  
GO:0046777 [list] [network] protein autophosphorylation  (198 genes)  ISO ISS  
GO:0060326 [list] [network] cell chemotaxis  (200 genes)  ISO ISS  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (232 genes)  ISO ISS  
GO:0001894 [list] [network] tissue homeostasis  (237 genes)  ISO  
GO:0048839 [list] [network] inner ear development  (239 genes)  IEP  
GO:0048705 [list] [network] skeletal system morphogenesis  (254 genes)  ISO  
GO:0032355 [list] [network] response to estradiol  (258 genes)  IEP  
GO:0050730 [list] [network] regulation of peptidyl-tyrosine phosphorylation  (273 genes)  ISO  
GO:0009636 [list] [network] response to toxic substance  (294 genes)  IEP  
GO:0042060 [list] [network] wound healing  (338 genes)  IEP  
GO:0001822 [list] [network] kidney development  (354 genes)  ISO  
GO:0032956 [list] [network] regulation of actin cytoskeleton organization  (368 genes)  ISO  
GO:0007169 [list] [network] transmembrane receptor protein tyrosine kinase signaling pathway  (369 genes)  IBA  
GO:0033674 [list] [network] positive regulation of kinase activity  (467 genes)  IBA  
GO:0007568 [list] [network] aging  (500 genes)  IEP  
GO:0001568 [list] [network] blood vessel development  (504 genes)  ISO  
GO:0048568 [list] [network] embryonic organ development  (530 genes)  ISO  
GO:0001701 [list] [network] in utero embryonic development  (540 genes)  ISO  
GO:0030335 [list] [network] positive regulation of cell migration  (586 genes)  ISO ISS  
GO:0043065 [list] [network] positive regulation of apoptotic process  (606 genes)  IMP  
GO:0030097 [list] [network] hemopoiesis  (692 genes)  ISO ISS  
GO:0016477 [list] [network] cell migration  (885 genes)  ISO ISS  
GO:0043066 [list] [network] negative regulation of apoptotic process  (978 genes)  IMP  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (1044 genes)  IMP ISO  
GO:0033993 [list] [network] response to lipid  (1302 genes)  IEP  
GO:0035556 [list] [network] intracellular signal transduction  (1357 genes)  IMP  
GO:0014070 [list] [network] response to organic cyclic compound  (1383 genes)  IEP  
GO:0007275 [list] [network] multicellular organism development  (4952 genes)  IBA  
GO:0007165 [list] [network] signal transduction  (5227 genes)  ISO  
GO:0006807 [list] [network] nitrogen compound metabolic process  (6134 genes)  ISO  
GO CC
GO:0043202 [list] [network] lysosomal lumen  (20 genes)  IEA  
GO:0001726 [list] [network] ruffle  (174 genes)  ISO  
GO:0016324 [list] [network] apical plasma membrane  (397 genes)  IDA  
GO:0043235 [list] [network] receptor complex  (398 genes)  IBA  
GO:0009986 [list] [network] cell surface  (937 genes)  IDA ISO  
GO:0005887 [list] [network] integral component of plasma membrane  (1281 genes)  IBA  
GO:0031226 [list] [network] intrinsic component of plasma membrane  (1365 genes)  ISO  
GO:0005794 [list] [network] Golgi apparatus  (1405 genes)  IEA ISO  
GO:0031410 [list] [network] cytoplasmic vesicle  (1869 genes)  IEA  
GO:0005886 [list] [network] plasma membrane  (5814 genes)  IDA  
GO:0005634 [list] [network] nucleus  (6599 genes)  IDA  
GO:0016020 [list] [network] membrane  (9382 genes)  ISO ISS  
GO:0005737 [list] [network] cytoplasm  (10463 genes)  IDA ISO  
GO:0043231 [list] [network] intracellular membrane-bounded organelle  (10581 genes)  ISO  
GO MF
GO:0005019 [list] [network] platelet-derived growth factor beta-receptor activity  (1 genes)  IBA ISO ISS  
GO:0005017 [list] [network] platelet-derived growth factor-activated receptor activity  (2 genes)  IDA ISO TAS  
GO:0038085 [list] [network] vascular endothelial growth factor binding  (5 genes)  ISO  
GO:0048407 [list] [network] platelet-derived growth factor binding  (11 genes)  IBA ISO  
GO:0005161 [list] [network] platelet-derived growth factor receptor binding  (14 genes)  ISO  
GO:0043548 [list] [network] phosphatidylinositol 3-kinase binding  (39 genes)  IPI  
GO:0004714 [list] [network] transmembrane receptor protein tyrosine kinase activity  (110 genes)  IBA  
GO:0004713 [list] [network] protein tyrosine kinase activity  (129 genes)  IDA ISO TAS  
GO:0019838 [list] [network] growth factor binding  (150 genes)  IBA  
GO:0004672 [list] [network] protein kinase activity  (557 genes)  TAS  
GO:0019901 [list] [network] protein kinase binding  (744 genes)  ISO  
GO:0016301 [list] [network] kinase activity  (757 genes)  ISO  
GO:0005524 [list] [network] ATP binding  (1380 genes)  IEA  
GO:0005102 [list] [network] signaling receptor binding  (1488 genes)  ISO  
GO:0019899 [list] [network] enzyme binding  (2185 genes)  ISO  
GO:0005515 [list] [network] protein binding  (7349 genes)  IPI  
KEGG rno01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (80 genes)
rno04010 [list] [network] MAPK signaling pathway (293 genes)
rno04014 [list] [network] Ras signaling pathway (231 genes)
rno04015 [list] [network] Rap1 signaling pathway (213 genes)
rno04020 [list] [network] Calcium signaling pathway (238 genes)
rno04072 [list] [network] Phospholipase D signaling pathway (150 genes)
rno04151 [list] [network] PI3K-Akt signaling pathway (345 genes)
rno04510 [list] [network] Focal adhesion (200 genes)
rno04540 [list] [network] Gap junction (87 genes)
rno04630 [list] [network] JAK-STAT signaling pathway (158 genes)
rno04810 [list] [network] Regulation of actin cytoskeleton (223 genes)
rno05165 [list] [network] Human papillomavirus infection (353 genes)
rno05200 [list] [network] Pathways in cancer (538 genes)
rno05206 [list] [network] MicroRNAs in cancer (292 genes)
rno05214 [list] [network] Glioma (74 genes)
rno05215 [list] [network] Prostate cancer (99 genes)
rno05218 [list] [network] Melanoma (73 genes)
rno05230 [list] [network] Central carbon metabolism in cancer (69 genes)
rno05231 [list] [network] Choline metabolism in cancer (98 genes)
Protein NP_113713.1  XP_038952501.1 
BLAST NP_113713.1  XP_038952501.1 
Orthologous [Ortholog page] PDGFRB (hsa)  Pdgfrb (mmu)  PDGFRB (cfa)  pdgfrb (dre)  PDGFRB (mcc)  PDGFRB (gga)  PDGFRB (fca) 
Subcellular
localization
wolf
plas 6,  E.R. 2,  pero 1  (predict for NP_113713.1)
plas 6,  E.R. 2,  pero 1  (predict for XP_038952501.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05200 Pathways in cancer 4
rno05206 MicroRNAs in cancer 3
rno04151 PI3K-Akt signaling pathway 3
rno04510 Focal adhesion 3
rno04540 Gap junction 3
Genes directly connected with Pdgfrb on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
6.1 Foxs1 forkhead box S1 [detail] 311547
5.9 S1pr3 sphingosine-1-phosphate receptor 3 [detail] 306792
5.9 Pdgfra platelet derived growth factor receptor alpha [detail] 25267
5.6 Emilin1 elastin microfibril interfacer 1 [detail] 298845
Coexpressed
gene list		 [Coexpressed gene list for Pdgfrb]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 24629      
Refseq ID (protein) NP_113713.1 
XP_038952501.1 


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