[←][→] fca  GRB2 Gene
functional annotation
Function   growth factor receptor bound protein 2  
GO BP
GO CC
GO MF
KEGG fca01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (80 genes)
fca01522 [list] [network] Endocrine resistance (96 genes)
fca04010 [list] [network] MAPK signaling pathway (289 genes)
fca04012 [list] [network] ErbB signaling pathway (84 genes)
fca04014 [list] [network] Ras signaling pathway (231 genes)
fca04062 [list] [network] Chemokine signaling pathway (183 genes)
fca04068 [list] [network] FoxO signaling pathway (129 genes)
fca04072 [list] [network] Phospholipase D signaling pathway (151 genes)
fca04150 [list] [network] mTOR signaling pathway (155 genes)
fca04151 [list] [network] PI3K-Akt signaling pathway (344 genes)
fca04380 [list] [network] Osteoclast differentiation (120 genes)
fca04510 [list] [network] Focal adhesion (201 genes)
fca04540 [list] [network] Gap junction (86 genes)
fca04550 [list] [network] Signaling pathways regulating pluripotency of stem cells (143 genes)
fca04630 [list] [network] JAK-STAT signaling pathway (159 genes)
fca04650 [list] [network] Natural killer cell mediated cytotoxicity (98 genes)
fca04660 [list] [network] T cell receptor signaling pathway (103 genes)
fca04662 [list] [network] B cell receptor signaling pathway (74 genes)
fca04664 [list] [network] Fc epsilon RI signaling pathway (69 genes)
fca04714 [list] [network] Thermogenesis (234 genes)
fca04722 [list] [network] Neurotrophin signaling pathway (121 genes)
fca04910 [list] [network] Insulin signaling pathway (140 genes)
fca04912 [list] [network] GnRH signaling pathway (93 genes)
fca04915 [list] [network] Estrogen signaling pathway (139 genes)
fca04917 [list] [network] Prolactin signaling pathway (71 genes)
fca04926 [list] [network] Relaxin signaling pathway (129 genes)
fca04935 [list] [network] Growth hormone synthesis, secretion and action (117 genes)
fca05034 [list] [network] Alcoholism (189 genes)
fca05160 [list] [network] Hepatitis C (153 genes)
fca05161 [list] [network] Hepatitis B (157 genes)
fca05163 [list] [network] Human cytomegalovirus infection (225 genes)
fca05165 [list] [network] Human papillomavirus infection (328 genes)
fca05200 [list] [network] Pathways in cancer (531 genes)
fca05203 [list] [network] Viral carcinogenesis (201 genes)
fca05205 [list] [network] Proteoglycans in cancer (212 genes)
fca05206 [list] [network] MicroRNAs in cancer (161 genes)
fca05207 [list] [network] Chemical carcinogenesis - receptor activation (181 genes)
fca05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (224 genes)
fca05210 [list] [network] Colorectal cancer (89 genes)
fca05211 [list] [network] Renal cell carcinoma (70 genes)
fca05213 [list] [network] Endometrial cancer (57 genes)
fca05214 [list] [network] Glioma (76 genes)
fca05215 [list] [network] Prostate cancer (95 genes)
fca05220 [list] [network] Chronic myeloid leukemia (75 genes)
fca05221 [list] [network] Acute myeloid leukemia (67 genes)
fca05223 [list] [network] Non-small cell lung cancer (72 genes)
fca05224 [list] [network] Breast cancer (146 genes)
fca05225 [list] [network] Hepatocellular carcinoma (163 genes)
fca05226 [list] [network] Gastric cancer (147 genes)
fca05231 [list] [network] Choline metabolism in cancer (97 genes)
Protein XP_023099758.1  XP_023099759.1 
BLAST XP_023099758.1  XP_023099759.1 
Orthologous [Ortholog page] GRB2 (hsa)  GRAP2 (hsa)  GRAP (hsa)  Grb2 (mmu)  Grap2 (mmu)  drk (dme)  Grap (mmu)  Grb2 (rno)  sem-5 (cel)  Grap (rno)  Grap2 (rno)  GRB2 (gga)  grap2b (dre)  GRAPL (hsa)  grb2b (dre)  GRAPL (gga)  GRAP2 (cfa)  GRB2 (cfa)  LOC489534 (cfa)  grb2a (dre)  grap2a (dre)  grapa (dre)  grapb (dre)  GRB2 (mcc)  GRAP (mcc)  GRAP2 (mcc)  GRAP2 (gga)  LSB1 (sce)  PIN3 (sce)  sla2a (dre)  GRAP2 (fca)  GRAP (fca) 
Subcellular
localization
wolf
cyto 9,  cyto_nucl 5  (predict for XP_023099758.1)
cyto 6,  extr 3,  cyto_nucl 3,  cyto_mito 3  (predict for XP_023099759.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04144 Endocytosis 5
fca05132 Salmonella infection 5
fca04014 Ras signaling pathway 3
fca04062 Chemokine signaling pathway 3
fca05200 Pathways in cancer 3
Genes directly connected with GRB2 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
5.8 GGA3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 [detail] 101098591
5.6 CAP1 cyclase associated actin cytoskeleton regulatory protein 1 [detail] 101097161
5.5 TBC1D10B TBC1 domain family member 10B [detail] 101086439
5.4 SMAP2 small ArfGAP2 [detail] 101098315
5.3 CDC42SE2 CDC42 small effector 2 [detail] 101092823
4.2 CYTH1 cytohesin 1 [detail] 101082609
Coexpressed
gene list		 [Coexpressed gene list for GRB2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 101099916      
Refseq ID (protein) XP_023099758.1 
XP_023099759.1 


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