[←][→] mcc  SOS1 Gene
functional annotation
Function   SOS Ras/Rac guanine nucleotide exchange factor 1  
GO BP
GO CC
GO MF
KEGG mcc01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (79 genes)
mcc01522 [list] [network] Endocrine resistance (98 genes)
mcc04010 [list] [network] MAPK signaling pathway (301 genes)
mcc04012 [list] [network] ErbB signaling pathway (85 genes)
mcc04014 [list] [network] Ras signaling pathway (250 genes)
mcc04062 [list] [network] Chemokine signaling pathway (200 genes)
mcc04068 [list] [network] FoxO signaling pathway (131 genes)
mcc04072 [list] [network] Phospholipase D signaling pathway (168 genes)
mcc04150 [list] [network] mTOR signaling pathway (155 genes)
mcc04151 [list] [network] PI3K-Akt signaling pathway (381 genes)
mcc04510 [list] [network] Focal adhesion (205 genes)
mcc04540 [list] [network] Gap junction (94 genes)
mcc04630 [list] [network] JAK-STAT signaling pathway (177 genes)
mcc04650 [list] [network] Natural killer cell mediated cytotoxicity (142 genes)
mcc04660 [list] [network] T cell receptor signaling pathway (107 genes)
mcc04662 [list] [network] B cell receptor signaling pathway (96 genes)
mcc04664 [list] [network] Fc epsilon RI signaling pathway (78 genes)
mcc04714 [list] [network] Thermogenesis (280 genes)
mcc04722 [list] [network] Neurotrophin signaling pathway (122 genes)
mcc04810 [list] [network] Regulation of actin cytoskeleton (221 genes)
mcc04910 [list] [network] Insulin signaling pathway (141 genes)
mcc04912 [list] [network] GnRH signaling pathway (97 genes)
mcc04915 [list] [network] Estrogen signaling pathway (144 genes)
mcc04917 [list] [network] Prolactin signaling pathway (70 genes)
mcc04926 [list] [network] Relaxin signaling pathway (133 genes)
mcc04935 [list] [network] Growth hormone synthesis, secretion and action (128 genes)
mcc05034 [list] [network] Alcoholism (204 genes)
mcc05160 [list] [network] Hepatitis C (173 genes)
mcc05161 [list] [network] Hepatitis B (180 genes)
mcc05163 [list] [network] Human cytomegalovirus infection (257 genes)
mcc05165 [list] [network] Human papillomavirus infection (352 genes)
mcc05200 [list] [network] Pathways in cancer (573 genes)
mcc05205 [list] [network] Proteoglycans in cancer (211 genes)
mcc05206 [list] [network] MicroRNAs in cancer (293 genes)
mcc05207 [list] [network] Chemical carcinogenesis - receptor activation (215 genes)
mcc05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (272 genes)
mcc05210 [list] [network] Colorectal cancer (107 genes)
mcc05211 [list] [network] Renal cell carcinoma (72 genes)
mcc05213 [list] [network] Endometrial cancer (61 genes)
mcc05214 [list] [network] Glioma (79 genes)
mcc05215 [list] [network] Prostate cancer (97 genes)
mcc05220 [list] [network] Chronic myeloid leukemia (80 genes)
mcc05221 [list] [network] Acute myeloid leukemia (69 genes)
mcc05223 [list] [network] Non-small cell lung cancer (75 genes)
mcc05224 [list] [network] Breast cancer (150 genes)
mcc05225 [list] [network] Hepatocellular carcinoma (177 genes)
mcc05226 [list] [network] Gastric cancer (153 genes)
mcc05231 [list] [network] Choline metabolism in cancer (107 genes)
Protein XP_028687574.1  XP_028687575.1 
BLAST XP_028687574.1  XP_028687575.1 
Orthologous [Ortholog page] SOS1 (hsa)  SOS2 (hsa)  Sos1 (mmu)  Sos2 (mmu)  Sos (dme)  Sos2 (rno)  sos-1 (cel)  Sos1 (rno)  SOS2 (gga)  SOS1 (gga)  SOS1 (cfa)  SOS2 (cfa)  sos1 (dre)  sos2 (dre)  SOS2 (mcc)  CDC25 (sce)  SOS2 (fca)  SOS1 (fca) 
Subcellular
localization
wolf
nucl 5,  cyto_nucl 4,  cyto 3  (predict for XP_028687574.1)
nucl 5,  cyto_nucl 4,  cyto 3  (predict for XP_028687575.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc03015 mRNA surveillance pathway 2
mcc01521 EGFR tyrosine kinase inhibitor resistance 2
mcc01522 Endocrine resistance 2
mcc04010 MAPK signaling pathway 2
mcc04012 ErbB signaling pathway 2
Genes directly connected with SOS1 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
7.3 RSBN1 round spermatid basic protein 1 [detail] 707312
6.2 PCNX1 pecanex 1 [detail] 694094
6.0 KIAA2026 KIAA2026 [detail] 717388
Coexpressed
gene list		 [Coexpressed gene list for SOS1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 713777      
Refseq ID (protein) XP_028687574.1 
XP_028687575.1 


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