[←][→] rno  Gnai3 Gene
functional annotation
Function   G protein subunit alpha i3  
GO BP
GO:0033864 [list] [network] positive regulation of NAD(P)H oxidase activity  (5 genes)  IMP  
GO:0032930 [list] [network] positive regulation of superoxide anion generation  (25 genes)  IMP  
GO:0046039 [list] [network] GTP metabolic process  (26 genes)  ISO ISS  
GO:0007212 [list] [network] dopamine receptor signaling pathway  (31 genes)  ISO ISS  
GO:1904707 [list] [network] positive regulation of vascular associated smooth muscle cell proliferation  (38 genes)  IMP  
GO:0016239 [list] [network] positive regulation of macroautophagy  (63 genes)  ISO  
GO:0007193 [list] [network] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (73 genes)  ISO ISS  
GO:0006906 [list] [network] vesicle fusion  (85 genes)  IDA  
GO:0008016 [list] [network] regulation of heart contraction  (198 genes)  ISO  
GO:0007188 [list] [network] adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (210 genes)  IBA  
GO:0051048 [list] [network] negative regulation of secretion  (216 genes)  TAS  
GO:2001234 [list] [network] negative regulation of apoptotic signaling pathway  (243 genes)  IMP  
GO:0051301 [list] [network] cell division  (366 genes)  ISO ISS  
GO:0007420 [list] [network] brain development  (960 genes)  IEP  
GO CC
GO:0042588 [list] [network] zymogen granule  (25 genes)  IDA  
GO:0005834 [list] [network] heterotrimeric G-protein complex  (34 genes)  IBA  
GO:0030496 [list] [network] midbody  (179 genes)  ISO ISS  
GO:0045121 [list] [network] membrane raft  (407 genes)  IDA  
GO:0000139 [list] [network] Golgi membrane  (418 genes)  ISO TAS  
GO:0005813 [list] [network] centrosome  (614 genes)  ISO ISS  
GO:0005789 [list] [network] endoplasmic reticulum membrane  (923 genes)  ISO  
GO:0005794 [list] [network] Golgi apparatus  (1405 genes)  ISO  
GO:0005886 [list] [network] plasma membrane  (5814 genes)  IDA ISO TAS  
GO:0016020 [list] [network] membrane  (9382 genes)  IDA  
GO:0005737 [list] [network] cytoplasm  (10463 genes)  ISO ISS  
GO MF
GO:0031821 [list] [network] G protein-coupled serotonin receptor binding  (5 genes)  IPI  
GO:0032794 [list] [network] GTPase activating protein binding  (19 genes)  IPI  
GO:0031683 [list] [network] G-protein beta/gamma-subunit complex binding  (25 genes)  IBA  
GO:0019003 [list] [network] GDP binding  (79 genes)  ISO ISS  
GO:0003924 [list] [network] GTPase activity  (279 genes)  IBA ISO ISS  
GO:0001664 [list] [network] G protein-coupled receptor binding  (307 genes)  IBA  
GO:0005525 [list] [network] GTP binding  (353 genes)  IEA  
GO:0019904 [list] [network] protein domain specific binding  (807 genes)  IPI  
GO:0046872 [list] [network] metal ion binding  (3303 genes)  IEA  
GO:0005515 [list] [network] protein binding  (7349 genes)  IPI  
KEGG rno04015 [list] [network] Rap1 signaling pathway (213 genes)
rno04022 [list] [network] cGMP-PKG signaling pathway (171 genes)
rno04024 [list] [network] cAMP signaling pathway (217 genes)
rno04062 [list] [network] Chemokine signaling pathway (182 genes)
rno04071 [list] [network] Sphingolipid signaling pathway (124 genes)
rno04261 [list] [network] Adrenergic signaling in cardiomyocytes (148 genes)
rno04360 [list] [network] Axon guidance (181 genes)
rno04371 [list] [network] Apelin signaling pathway (137 genes)
rno04540 [list] [network] Gap junction (87 genes)
rno04611 [list] [network] Platelet activation (126 genes)
rno04670 [list] [network] Leukocyte transendothelial migration (117 genes)
rno04713 [list] [network] Circadian entrainment (98 genes)
rno04723 [list] [network] Retrograde endocannabinoid signaling (151 genes)
rno04724 [list] [network] Glutamatergic synapse (114 genes)
rno04725 [list] [network] Cholinergic synapse (113 genes)
rno04726 [list] [network] Serotonergic synapse (123 genes)
rno04727 [list] [network] GABAergic synapse (91 genes)
rno04728 [list] [network] Dopaminergic synapse (132 genes)
rno04730 [list] [network] Long-term depression (61 genes)
rno04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes)
rno04915 [list] [network] Estrogen signaling pathway (135 genes)
rno04916 [list] [network] Melanogenesis (99 genes)
rno04921 [list] [network] Oxytocin signaling pathway (155 genes)
rno04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes)
rno04924 [list] [network] Renin secretion (72 genes)
rno04926 [list] [network] Relaxin signaling pathway (128 genes)
rno04928 [list] [network] Parathyroid hormone synthesis, secretion and action (105 genes)
rno04934 [list] [network] Cushing syndrome (158 genes)
rno04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes)
rno04971 [list] [network] Gastric acid secretion (75 genes)
rno05012 [list] [network] Parkinson disease (270 genes)
rno05030 [list] [network] Cocaine addiction (47 genes)
rno05032 [list] [network] Morphine addiction (92 genes)
rno05034 [list] [network] Alcoholism (177 genes)
rno05133 [list] [network] Pertussis (73 genes)
rno05142 [list] [network] Chagas disease (104 genes)
rno05145 [list] [network] Toxoplasmosis (111 genes)
rno05163 [list] [network] Human cytomegalovirus infection (248 genes)
rno05170 [list] [network] Human immunodeficiency virus 1 infection (234 genes)
rno05200 [list] [network] Pathways in cancer (538 genes)
rno05207 [list] [network] Chemical carcinogenesis - receptor activation (228 genes)
Protein NP_037238.1 
BLAST NP_037238.1 
Orthologous [Ortholog page] GNA11 (hsa)  GNAI1 (hsa)  GNAI2 (hsa)  GNAI3 (hsa)  GNAO1 (hsa)  GNAQ (hsa)  GNAT1 (hsa)  GNAT2 (hsa)  GNAZ (hsa)  GNA14 (hsa)  Gna11 (mmu)  Gna14 (mmu)  Gnai1 (mmu)  Gnai2 (mmu)  Gnai3 (mmu)  Gnao1 (mmu)  Gnaq (mmu)  Gnat1 (mmu)  Gnat2 (mmu)  Gnaz (mmu)  Gnai1 (rno)  Gnaz (rno)  Galphao (dme)  Galphaq (dme)  CG17760 (dme)  Galphai (dme)  Gnao1 (rno)  Gna11 (rno)  Gnai2 (rno)  Gnaq (rno)  gnat1 (dre)  gnat2 (dre)  gpa-16 (cel)  egl-30 (cel)  goa-1 (cel)  gpa-15 (cel)  gpa-4 (cel)  gpa-7 (cel)  gpa-2 (cel)  gpa-3 (cel)  gpa-1 (cel)  gpa-8 (cel)  odr-3 (cel)  Gnat3 (mmu)  CG30054 (dme)  Gnat3 (rno)  Gna14 (rno)  gnaia (dre)  gnai2b (dre)  gnai2a (dre)  GNAT3 (hsa)  Gnat1 (rno)  Gnat2 (rno)  GNA11 (gga)  GNAI3 (gga)  gnao1a (dre)  gnao1b (dre)  gnai1 (dre)  GNAT2 (gga)  GNAT1 (gga)  GNAI2 (gga)  GNAI1 (gga)  GNAT1 (cfa)  GNA11 (cfa)  GNAQ (cfa)  GNAO1 (gga)  GNAQ (gga)  GNAT3 (gga)  GNA14 (gga)  GNAI2 (cfa)  gna15.1 (dre)  gna14 (dre)  GNAI1 (cfa)  GNA14 (cfa)  GNAT2 (cfa)  GNAT3 (cfa)  gna11b (dre)  gna14a (dre)  gna11a (dre)  gnaz (dre)  gnaq (dre)  gnav1 (dre)  GNAO1 (mcc)  GNAZ (cfa)  GNAO1 (cfa)  GNAI3 (cfa)  GNAI3 (mcc)  GNAT2 (mcc)  GNAI2 (mcc)  GNAT1 (mcc)  GNA14 (mcc)  GNAQ (mcc)  GNAZ (mcc)  GNAT3 (mcc)  GNAI1 (mcc)  GNA11 (mcc)  GNAZ (gga)  GPA1 (sce)  GPA2 (sce)  gnai3 (dre)  gna15.2 (dre)  GNA11 (fca)  GNAI2 (fca)  GNAT1 (fca)  GNAI1 (fca)  GNAT3 (fca)  GNA14 (fca)  GNAQ (fca)  GNAI3 (fca)  GNAT2 (fca)  GNAZ (fca)  GNAO1 (fca) 
Subcellular
localization
wolf
cyto 7,  mito_pero 1,  plas 1,  mito 1,  pero 1,  extr_plas 1  (predict for NP_037238.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05170 Human immunodeficiency virus 1 infection 4
rno05161 Hepatitis B 3
rno05203 Viral carcinogenesis 3
rno04010 MAPK signaling pathway 3
rno04015 Rap1 signaling pathway 3
Genes directly connected with Gnai3 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
9.6 Api5 apoptosis inhibitor 5 [detail] 362170
8.7 Pak2 p21 (RAC1) activated kinase 2 [detail] 29432
8.3 Ddx3x DEAD-box helicase 3, X-linked [detail] 317335
8.2 Eif4g2 eukaryotic translation initiation factor 4, gamma 2 [detail] 361628
7.9 Septin2 septin 2 [detail] 117515
7.5 Hnrnpf heterogeneous nuclear ribonucleoprotein F [detail] 64200
7.5 Seh1l SEH1-like nucleoporin [detail] 100911798
7.0 Nras NRAS proto-oncogene, GTPase [detail] 24605
6.4 Ptpn12 protein tyrosine phosphatase, non-receptor type 12 [detail] 117255
6.3 Prkd3 protein kinase D3 [detail] 313834
6.3 Twf1 twinfilin actin-binding protein 1 [detail] 315265
6.3 Tmod3 tropomodulin 3 [detail] 300838
5.9 Capza1 capping actin protein of muscle Z-line subunit alpha 1 [detail] 691149
5.8 Pi4k2b phosphatidylinositol 4-kinase type 2 beta [detail] 305419
5.7 Casp3 caspase 3 [detail] 25402
Coexpressed
gene list		 [Coexpressed gene list for Gnai3]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 25643      
Refseq ID (protein) NP_037238.1 


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