| functional annotation |
| Function |
platelet derived growth factor C |
|
| GO BP |
|
GO:0007171 [list] [network] activation of transmembrane receptor protein tyrosine kinase activity
|
(9 genes)
|
ISO
|
 |
|
GO:0031954 [list] [network] positive regulation of protein autophosphorylation
|
(26 genes)
|
IBA
|
|
|
GO:0048008 [list] [network] platelet-derived growth factor receptor signaling pathway
|
(39 genes)
|
IBA
IEA
ISO
|
|
|
GO:0048146 [list] [network] positive regulation of fibroblast proliferation
|
(75 genes)
|
ISO
|
|
|
GO:0051781 [list] [network] positive regulation of cell division
|
(76 genes)
|
IEA
|
|
|
GO:0014068 [list] [network] positive regulation of phosphatidylinositol 3-kinase signaling
|
(81 genes)
|
IBA
|
|
|
GO:0120162 [list] [network] positive regulation of cold-induced thermogenesis
|
(99 genes)
|
ISO
ISS
|
|
|
GO:0043406 [list] [network] positive regulation of MAP kinase activity
|
(101 genes)
|
IBA
|
|
|
GO:0048565 [list] [network] digestive tract development
|
(162 genes)
|
ISO
|
|
|
GO:0071230 [list] [network] cellular response to amino acid stimulus
|
(165 genes)
|
ISO
|
|
|
GO:0060348 [list] [network] bone development
|
(230 genes)
|
ISO
|
|
|
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade
|
(232 genes)
|
IBA
|
|
|
GO:0050730 [list] [network] regulation of peptidyl-tyrosine phosphorylation
|
(273 genes)
|
ISO
|
|
|
GO:0048568 [list] [network] embryonic organ development
|
(530 genes)
|
IEA
|
|
|
GO:0030335 [list] [network] positive regulation of cell migration
|
(586 genes)
|
IBA
|
|
|
GO:0008284 [list] [network] positive regulation of cell population proliferation
|
(1044 genes)
|
IBA
IEA
ISO
|
|
|
GO:0009887 [list] [network] animal organ morphogenesis
|
(1076 genes)
|
ISO
|
|
|
| GO CC |
|
GO:0009986 [list] [network] cell surface
|
(937 genes)
|
ISO
|
|
|
GO:0005615 [list] [network] extracellular space
|
(1510 genes)
|
IBA
ISO
|
|
|
GO:0005576 [list] [network] extracellular region
|
(2120 genes)
|
IEA
ISO
|
|
|
GO:0005829 [list] [network] cytosol
|
(3690 genes)
|
IEA
ISO
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5814 genes)
|
IEA
ISO
|
|
|
GO:0005634 [list] [network] nucleus
|
(6599 genes)
|
IEA
|
|
|
GO:0016020 [list] [network] membrane
|
(9382 genes)
|
IEA
|
|
|
| GO MF |
|
GO:0005161 [list] [network] platelet-derived growth factor receptor binding
|
(14 genes)
|
IBA
IEA
ISO
|
|
|
GO:0008083 [list] [network] growth factor activity
|
(145 genes)
|
IEA
|
|
|
GO:0070851 [list] [network] growth factor receptor binding
|
(150 genes)
|
IBA
|
|
|
GO:0042803 [list] [network] protein homodimerization activity
|
(699 genes)
|
ISO
|
|
|
| KEGG |
rno01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (80 genes) |
 |
| rno04010 [list] [network] MAPK signaling pathway (293 genes) |
|
| rno04014 [list] [network] Ras signaling pathway (231 genes) |
|
| rno04015 [list] [network] Rap1 signaling pathway (213 genes) |
|
| rno04020 [list] [network] Calcium signaling pathway (238 genes) |
|
| rno04072 [list] [network] Phospholipase D signaling pathway (150 genes) |
|
| rno04151 [list] [network] PI3K-Akt signaling pathway (345 genes) |
|
| rno04510 [list] [network] Focal adhesion (200 genes) |
|
| rno04540 [list] [network] Gap junction (87 genes) |
|
| rno04810 [list] [network] Regulation of actin cytoskeleton (223 genes) |
|
| rno05215 [list] [network] Prostate cancer (99 genes) |
|
| rno05218 [list] [network] Melanoma (73 genes) |
|
| rno05231 [list] [network] Choline metabolism in cancer (98 genes) |
|
| Protein |
NP_112607.1
XP_038959124.1
XP_038959125.1
XP_038959126.1
|
| BLAST |
NP_112607.1
XP_038959124.1
XP_038959125.1
XP_038959126.1
|
| Orthologous |
[Ortholog page]
Pdgfc (mmu)
PDGFC (hsa)
PDGFC (gga)
PDGFC (cfa)
pdgfc (dre)
PDGFC (mcc)
PDGFC (fca)
|
Subcellular
localization
wolf |
|
extr 9,
lyso 1
|
(predict for NP_112607.1)
|
|
extr 6,
cyto 2,
cyto_nucl 1,
mito 1,
lyso 1
|
(predict for XP_038959124.1)
|
|
extr 6,
cyto 2,
cyto_nucl 1,
mito 1,
lyso 1
|
(predict for XP_038959125.1)
|
|
extr 6,
cyto 2,
cyto_nucl 1,
mito 1,
lyso 1
|
(predict for XP_038959126.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| rno05200 |
Pathways in cancer |
4 |
 |
| rno04810 |
Regulation of actin cytoskeleton |
4 |
 |
| rno04015 |
Rap1 signaling pathway |
3 |
 |
| rno04360 |
Axon guidance |
3 |
 |
| rno04151 |
PI3K-Akt signaling pathway |
3 |
 |
Genes directly connected with Pdgfc on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 5.3 |
Adgra3 |
adhesion G protein-coupled receptor A3 |
[detail] |
305408 |
| 4.7 |
Fgfrl1 |
fibroblast growth factor receptor-like 1 |
[detail] |
360903 |
| 4.3 |
Itga6 |
integrin subunit alpha 6 |
[detail] |
114517 |
|
Coexpressed
gene list |
[Coexpressed gene list for Pdgfc]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Pdgfc Gene
