[←][→] cfa  SOS2 Gene
functional annotation
Function   SOS Ras/Rho guanine nucleotide exchange factor 2  
GO BP
GO CC
GO MF
KEGG cfa01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (84 genes)
cfa01522 [list] [network] Endocrine resistance (94 genes)
cfa04010 [list] [network] MAPK signaling pathway (288 genes)
cfa04012 [list] [network] ErbB signaling pathway (83 genes)
cfa04014 [list] [network] Ras signaling pathway (229 genes)
cfa04062 [list] [network] Chemokine signaling pathway (180 genes)
cfa04068 [list] [network] FoxO signaling pathway (127 genes)
cfa04072 [list] [network] Phospholipase D signaling pathway (150 genes)
cfa04150 [list] [network] mTOR signaling pathway (161 genes)
cfa04151 [list] [network] PI3K-Akt signaling pathway (359 genes)
cfa04510 [list] [network] Focal adhesion (201 genes)
cfa04540 [list] [network] Gap junction (88 genes)
cfa04630 [list] [network] JAK-STAT signaling pathway (156 genes)
cfa04650 [list] [network] Natural killer cell mediated cytotoxicity (99 genes)
cfa04660 [list] [network] T cell receptor signaling pathway (102 genes)
cfa04662 [list] [network] B cell receptor signaling pathway (67 genes)
cfa04664 [list] [network] Fc epsilon RI signaling pathway (66 genes)
cfa04714 [list] [network] Thermogenesis (263 genes)
cfa04722 [list] [network] Neurotrophin signaling pathway (118 genes)
cfa04810 [list] [network] Regulation of actin cytoskeleton (229 genes)
cfa04910 [list] [network] Insulin signaling pathway (140 genes)
cfa04912 [list] [network] GnRH signaling pathway (89 genes)
cfa04915 [list] [network] Estrogen signaling pathway (138 genes)
cfa04917 [list] [network] Prolactin signaling pathway (69 genes)
cfa04926 [list] [network] Relaxin signaling pathway (130 genes)
cfa04935 [list] [network] Growth hormone synthesis, secretion and action (114 genes)
cfa05034 [list] [network] Alcoholism (188 genes)
cfa05160 [list] [network] Hepatitis C (158 genes)
cfa05161 [list] [network] Hepatitis B (160 genes)
cfa05163 [list] [network] Human cytomegalovirus infection (219 genes)
cfa05165 [list] [network] Human papillomavirus infection (329 genes)
cfa05200 [list] [network] Pathways in cancer (537 genes)
cfa05205 [list] [network] Proteoglycans in cancer (206 genes)
cfa05206 [list] [network] MicroRNAs in cancer (276 genes)
cfa05207 [list] [network] Chemical carcinogenesis - receptor activation (197 genes)
cfa05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (238 genes)
cfa05210 [list] [network] Colorectal cancer (88 genes)
cfa05211 [list] [network] Renal cell carcinoma (71 genes)
cfa05213 [list] [network] Endometrial cancer (58 genes)
cfa05214 [list] [network] Glioma (74 genes)
cfa05215 [list] [network] Prostate cancer (99 genes)
cfa05220 [list] [network] Chronic myeloid leukemia (74 genes)
cfa05221 [list] [network] Acute myeloid leukemia (65 genes)
cfa05223 [list] [network] Non-small cell lung cancer (71 genes)
cfa05224 [list] [network] Breast cancer (145 genes)
cfa05225 [list] [network] Hepatocellular carcinoma (165 genes)
cfa05226 [list] [network] Gastric cancer (146 genes)
cfa05231 [list] [network] Choline metabolism in cancer (96 genes)
Protein XP_038442612.1  XP_038442613.1  XP_038529511.1  XP_038529512.1 
BLAST XP_038442612.1  XP_038442613.1  XP_038529511.1  XP_038529512.1 
Orthologous [Ortholog page] SOS1 (hsa)  SOS2 (hsa)  Sos1 (mmu)  Sos2 (mmu)  Sos (dme)  Sos2 (rno)  sos-1 (cel)  Sos1 (rno)  SOS2 (gga)  SOS1 (gga)  SOS1 (cfa)  sos1 (dre)  sos2 (dre)  SOS2 (mcc)  SOS1 (mcc)  CDC25 (sce)  SOS2 (fca)  SOS1 (fca) 
Subcellular
localization
wolf
nucl 5,  cyto 3,  cysk 1  (predict for XP_038442612.1)
nucl 5,  cyto 3,  cysk 1  (predict for XP_038442613.1)
nucl 5,  cyto 3,  cysk 1  (predict for XP_038529511.1)
nucl 5,  cyto 3,  cysk 1  (predict for XP_038529512.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04010 MAPK signaling pathway 3
cfa04068 FoxO signaling pathway 2
cfa04630 JAK-STAT signaling pathway 2
cfa04722 Neurotrophin signaling pathway 2
cfa04912 GnRH signaling pathway 2
Genes directly connected with SOS2 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
6.5 KANSL1 KAT8 regulatory NSL complex subunit 1 [detail] 119881599
6.4 ARID4A AT-rich interaction domain 4A [detail] 480339
6.2 NAA30 N-alpha-acetyltransferase 30, NatC catalytic subunit [detail] 612880
5.8 MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 [detail] 490685
5.6 KDM7A lysine demethylase 7A [detail] 482769
5.5 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A [detail] 480344
5.4 FEM1C fem-1 homolog C [detail] 481437
3.7 LOC111094294 uncharacterized LOC111094294 [detail] 111094294
Coexpressed
gene list		 [Coexpressed gene list for SOS2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 490682      
Refseq ID (protein) XP_038442612.1 
XP_038442613.1 
XP_038529511.1 
XP_038529512.1 


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