KEGG 04015 Rap1 signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04015 Rap1 signaling pathway 91
hsa04014 Ras signaling pathway 49
hsa05200 Pathways in cancer 46
hsa04810 Regulation of actin cytoskeleton 38
hsa04151 PI3K-Akt signaling pathway 38
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04015 Rap1 signaling pathway 107
mmu04014 Ras signaling pathway 62
mmu05200 Pathways in cancer 59
mmu04010 MAPK signaling pathway 56
mmu04151 PI3K-Akt signaling pathway 48
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04015 Rap1 signaling pathway 100
rno05200 Pathways in cancer 56
rno04014 Ras signaling pathway 51
rno04010 MAPK signaling pathway 43
rno04810 Regulation of actin cytoskeleton 43
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04015 Rap1 signaling pathway 94
mcc04014 Ras signaling pathway 46
mcc05200 Pathways in cancer 44
mcc04810 Regulation of actin cytoskeleton 41
mcc04510 Focal adhesion 39
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04015 Rap1 signaling pathway 108
cfa05200 Pathways in cancer 50
cfa04014 Ras signaling pathway 47
cfa04010 MAPK signaling pathway 42
cfa04151 PI3K-Akt signaling pathway 38
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04015 Rap1 signaling pathway 94
fca04014 Ras signaling pathway 55
fca05200 Pathways in cancer 55
fca04010 MAPK signaling pathway 48
fca04151 PI3K-Akt signaling pathway 46
Gene list in the network
Symbol Function*
ACTB actin beta
ACTG1 actin gamma 1
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8
ADCY9 adenylate cyclase 9
AKT1 AKT serine/threonine kinase 1
AKT2 AKT serine/threonine kinase 2
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
RHOA ras homolog family member A
FMNL1 formin like 1
CALM1 calmodulin 1
CALM2 calmodulin 2
CALM3 calmodulin 3
CALML3 calmodulin like 3
CDH5 cadherin 5
CFL1 cofilin 1
CNN2 calponin 2
COL6A3 collagen type VI alpha 3 chain
CRKL CRK like proto-oncogene, adaptor protein
DCN decorin
DOCK2 dedicator of cytokinesis 2
LPAR1 lysophosphatidic acid receptor 1
EFNA1 ephrin A1
EFNA3 ephrin A3
EFNA4 ephrin A4
EPHA2 EPH receptor A2
FGF2 fibroblast growth factor 2
FGF5 fibroblast growth factor 5
FGF7 fibroblast growth factor 7
FGF10 fibroblast growth factor 10
FGFR3 fibroblast growth factor receptor 3
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FLT1 fms related receptor tyrosine kinase 1
FYB1 FYN binding protein 1
GNAI2 G protein subunit alpha i2
GNAI3 G protein subunit alpha i3
GNAO1 G protein subunit alpha o1
GNAS GNAS complex locus
GNAZ G protein subunit alpha z
RAPGEF1 Rap guanine nucleotide exchange factor 1
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
ARHGAP35 Rho GTPase activating protein 35
NCKAP1L NCK associated protein 1 like
HGF hepatocyte growth factor
ID1 inhibitor of DNA binding 1, HLH protein
ITGA2B integrin subunit alpha 2b
ITGAL integrin subunit alpha L
ITGAM integrin subunit alpha M
ITGB2 integrin subunit beta 2
ITPR3 inositol 1,4,5-trisphosphate receptor type 3
KDR kinase insert domain receptor
KRAS KRAS proto-oncogene, GTPase
LCP2 lymphocyte cytosolic protein 2
AFDN afadin, adherens junction formation factor
MYO1F myosin IF
NRAS NRAS proto-oncogene, GTPase
PCDH1 protocadherin 1
PDGFB platelet derived growth factor subunit B
PDGFRA platelet derived growth factor receptor alpha
PDGFRB platelet derived growth factor receptor beta
PFN1 profilin 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PLCB2 phospholipase C beta 2
PLCB4 phospholipase C beta 4
PLCG1 phospholipase C gamma 1
PODXL podocalyxin like
PRKCA protein kinase C alpha
PRKCB protein kinase C beta
PRKCI protein kinase C iota
PRKD1 protein kinase D1
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK13 mitogen-activated protein kinase 13
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
RAC1 Rac family small GTPase 1
RALB RAS like proto-oncogene B
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
MAPK12 mitogen-activated protein kinase 12
SPN sialophorin
STXBP3 syntaxin binding protein 3
TEK TEK receptor tyrosine kinase
TPM4 tropomyosin 4
USF2 upstream transcription factor 2, c-fos interacting
VASP vasodilator stimulated phosphoprotein
VAV1 vav guanine nucleotide exchange factor 1
VAV2 vav guanine nucleotide exchange factor 2
VEGFC vascular endothelial growth factor C
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
ZYX zyxin
MTA1 metastasis associated 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
BCAR1 BCAR1 scaffold protein, Cas family member
GNA14 G protein subunit alpha 14
RAPGEF5 Rap guanine nucleotide exchange factor 5
WDR1 WD repeat domain 1
ARPC4 actin related protein 2/3 complex subunit 4
ACTR3 actin related protein 3
ACTR2 actin related protein 2
RAPGEF3 Rap guanine nucleotide exchange factor 3
RGS14 regulator of G protein signaling 14
ZHX3 zinc fingers and homeoboxes 3
SIPA1L3 signal induced proliferation associated 1 like 3
ATP11B ATPase phospholipid transporting 11B (putative)
COTL1 coactosin like F-actin binding protein 1
ARHGAP45 Rho GTPase activating protein 45
UBXN7 UBX domain protein 7
PLCE1 phospholipase C epsilon 1
BIN2 bridging integrator 2
EVL Enah/Vasp-like
HDAC7 histone deacetylase 7
CALML5 calmodulin like 5
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
FBLIM1 filamin binding LIM protein 1
ALKBH5 alkB homolog 5, RNA demethylase
SAMD4B sterile alpha motif domain containing 4B
LPAR5 lysophosphatidic acid receptor 5
SHROOM3 shroom family member 3
TRAPPC1 trafficking protein particle complex subunit 1
ADGRL4 adhesion G protein-coupled receptor L4
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
CPED1 cadherin like and PC-esterase domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
RASSF5 Ras association domain family member 5
TMEM47 transmembrane protein 47
TLN2 talin 2
ACRBP acrosin binding protein
KIF12 kinesin family member 12
TMEM132B transmembrane protein 132B
TM4SF18 transmembrane 4 L six family member 18
CCBE1 collagen and calcium binding EGF domains 1
ADCY4 adenylate cyclase 4
TUBB tubulin beta class I
ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ARHGAP30 Rho GTPase activating protein 30
LOC105371058 uncharacterized LOC105371058
Symbol Function*
Actb actin, beta
Actg1 actin, gamma, cytoplasmic 1
Adcy7 adenylate cyclase 7
Adcy9 adenylate cyclase 9
Angpt1 angiopoietin 1
Angpt2 angiopoietin 2
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Rhoa ras homolog family member A
Calm1 calmodulin 1
Calm2 calmodulin 2
Calm3 calmodulin 3
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast)
Capns1 calpain, small subunit 1
Capza1 capping protein (actin filament) muscle Z-line, alpha 1
Ctnna1 catenin (cadherin associated protein), alpha 1
Ctnnd1 catenin (cadherin associated protein), delta 1
Cd37 CD37 antigen
Cd3g CD3 antigen, gamma polypeptide
Cdc42 cell division cycle 42
Arhgap31 Rho GTPase activating protein 31
Cdh5 cadherin 5
Cfl1 cofilin 1, non-muscle
Coro1a coronin, actin binding protein 1A
Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like
Csk c-src tyrosine kinase
Twist2 twist basic helix-loop-helix transcription factor 2
Ednra endothelin receptor type A
Efna1 ephrin A1
Efna3 ephrin A3
Efna4 ephrin A4
Egfr epidermal growth factor receptor
F2rl3 coagulation factor II (thrombin) receptor-like 3
Fgf10 fibroblast growth factor 10
Fgf18 fibroblast growth factor 18
Fgf7 fibroblast growth factor 7
Fgfr2 fibroblast growth factor receptor 2
Fgfr3 fibroblast growth factor receptor 3
Flt1 FMS-like tyrosine kinase 1
Flt4 FMS-like tyrosine kinase 4
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3
Gnb2 guanine nucleotide binding protein (G protein), beta 2
Gpc4 glypican 4
Lpar1 lysophosphatidic acid receptor 1
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1
Hcls1 hematopoietic cell specific Lyn substrate 1
Ptpn6 protein tyrosine phosphatase, non-receptor type 6
Hgf hepatocyte growth factor
Hras Harvey rat sarcoma virus oncogene
Ins1 insulin I
Ins2 insulin II
Itga2b integrin alpha 2b
Itgal integrin alpha L
Itgam integrin alpha M
Itgb1 integrin beta 1 (fibronectin receptor beta)
Itgb2 integrin beta 2
Itgb3 integrin beta 3
Kdr kinase insert domain protein receptor
Kras Kirsten rat sarcoma viral oncogene homolog
Ksr1 kinase suppressor of ras 1
Lat linker for activation of T cells
Lcp2 lymphocyte cytosolic protein 2
Lor loricrin
Lrmp lymphoid-restricted membrane protein
Mbd3 methyl-CpG binding domain protein 3
Met met proto-oncogene
Kitl kit ligand
Afdn afadin, adherens junction formation factor
Mras muscle and microspikes RAS
Septin2 septin 2
Ngf nerve growth factor
Nras neuroblastoma ras oncogene
Nrp2 neuropilin 2
Pdgfa platelet derived growth factor, alpha
Pdgfb platelet derived growth factor, B polypeptide
Pdgfra platelet derived growth factor receptor, alpha polypeptide
Pdgfrb platelet derived growth factor receptor, beta polypeptide
Pfn1 profilin 1
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Prkca protein kinase C, alpha
Prkcb protein kinase C, beta
Prkci protein kinase C, iota
Plcb2 phospholipase C, beta 2
Plcb3 phospholipase C, beta 3
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Mapk11 mitogen-activated protein kinase 11
Ptgfr prostaglandin F receptor
Ptprb protein tyrosine phosphatase, receptor type, B
Ptprc protein tyrosine phosphatase, receptor type, C
Ptprk protein tyrosine phosphatase, receptor type, K
Rac1 Rac family small GTPase 1
Rac2 Rac family small GTPase 2
Rasgrp2 RAS, guanyl releasing protein 2
Ralgds ral guanine nucleotide dissociation stimulator
Rras related RAS viral (r-ras) oncogene
Cavin2 caveolae associated 2
Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Sipa1 signal-induced proliferation associated gene 1
Sox18 SRY (sex determining region Y)-box 18
Src Rous sarcoma oncogene
Tek TEK receptor tyrosine kinase
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Tjp1 tight junction protein 1
Try4 trypsin 4
Vasp vasodilator-stimulated phosphoprotein
Vav1 vav 1 oncogene
Vav2 vav 2 oncogene
Vegfb vascular endothelial growth factor B
Vegfc vascular endothelial growth factor C
Trpv2 transient receptor potential cation channel, subfamily V, member 2
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Ikzf1 IKAROS family zinc finger 1
Fyb FYN binding protein
Map2k2 mitogen-activated protein kinase kinase 2
Map4k2 mitogen-activated protein kinase kinase kinase kinase 2
Mapk1 mitogen-activated protein kinase 1
Mapk14 mitogen-activated protein kinase 14
Mapk3 mitogen-activated protein kinase 3
Podxl podocalyxin-like
Sh2d3c SH2 domain containing 3C
Mapk12 mitogen-activated protein kinase 12
Rgs14 regulator of G-protein signaling 14
Batf basic leucine zipper transcription factor, ATF-like
Lpar2 lysophosphatidic acid receptor 2
Rassf5 Ras association (RalGDS/AF-6) domain family member 5
Gp9 glycoprotein 9 (platelet)
Apbb1ip amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Pdgfc platelet-derived growth factor, C polypeptide
Hdac7 histone deacetylase 7
Nudt3 nudix (nucleotide diphosphate linked moiety X)-type motif 3
Mtch1 mitochondrial carrier 1
Gmfg glia maturation factor, gamma
Ralb v-ral simian leukemia viral oncogene B
Clec14a C-type lectin domain family 14, member a
Arpc4 actin related protein 2/3 complex, subunit 4
Calml3 calmodulin-like 3
Dlg5 discs large MAGUK scaffold protein 5
Treml1 triggering receptor expressed on myeloid cells-like 1
Ptk7 PTK7 protein tyrosine kinase 7
Rap2b RAP2B, member of RAS oncogene family
Vsir V-set immunoregulatory receptor
Actr3 ARP3 actin-related protein 3
Sash3 SAM and SH3 domain containing 3
Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2
Ccdc88b coiled-coil domain containing 88B
Skap1 src family associated phosphoprotein 1
Gmip Gem-interacting protein
Calm4 calmodulin 4
Pard6g par-6 family cell polarity regulator gamma
Pard3 par-3 family cell polarity regulator
Vangl2 VANGL planar cell polarity 2
Dock2 dedicator of cyto-kinesis 2
Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3
Prkd2 protein kinase D2
Slc6a8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8
Csnk1g2 casein kinase 1, gamma 2
Adcy4 adenylate cyclase 4
Mmrn2 multimerin 2
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Braf Braf transforming gene
Rap1a RAS-related protein 1a
Hdac10 histone deacetylase 10
Rapgef6 Rap guanine nucleotide exchange factor (GEF) 6
Rap1b RAS related protein 1b
Unc45b unc-45 myosin chaperone B
Sipa1l1 signal-induced proliferation-associated 1 like 1
Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3
Adgrf5 adhesion G protein-coupled receptor F5
Map4k3 mitogen-activated protein kinase kinase kinase kinase 3
Gm94 predicted gene 94
Arhgap30 Rho GTPase activating protein 30
4932438A13Rik RIKEN cDNA 4932438A13 gene
Dock4 dedicator of cytokinesis 4
Rasgrp3 RAS, guanyl releasing protein 3
Myo1g myosin IG
Rasal3 RAS protein activator like 3
Lpar5 lysophosphatidic acid receptor 5
Cracr2a calcium release activated channel regulator 2A
Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15
Bin2 bridging integrator 2
Symbol Function*
Calm1 calmodulin 1
Calm3 calmodulin 3
Drd2 dopamine receptor D2
Hgf hepatocyte growth factor
Itgb1 integrin subunit beta 1
Kras KRAS proto-oncogene, GTPase
Nras NRAS proto-oncogene, GTPase
Pdgfb platelet derived growth factor subunit B
Pdgfrb platelet derived growth factor receptor beta
Prkcg protein kinase C, gamma
Ptprc protein tyrosine phosphatase, receptor type, C
Rarb retinoic acid receptor, beta
Itgam integrin subunit alpha M
Fgfr2 fibroblast growth factor receptor 2
Calcrl calcitonin receptor like receptor
Vav1 vav guanine nucleotide exchange factor 1
Acvrl1 activin A receptor like type 1
Cnr1 cannabinoid receptor 1
Pdgfra platelet derived growth factor receptor alpha
Adcy6 adenylate cyclase 6
Fgf1 fibroblast growth factor 1
Adora2a adenosine A2a receptor
Casp3 caspase 3
Bcar1 BCAR1 scaffold protein, Cas family member
F2r coagulation factor II (thrombin) receptor
Fgf10 fibroblast growth factor 10
Kdr kinase insert domain receptor
Agrn agrin
Gnai3 G protein subunit alpha i3
Cd3d CD3d molecule
Igf1r insulin-like growth factor 1 receptor
Hck HCK proto-oncogene, Src family tyrosine kinase
Plcg1 phospholipase C, gamma 1
Afdn afadin, adherens junction formation factor
Cfl1 cofilin 1
Itgb3 integrin subunit beta 3
Plcb3 phospholipase C beta 3
Prkce protein kinase C, epsilon
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Calm2 calmodulin 2
Adcy4 adenylate cyclase 4
Cr1l complement C3b/C4b receptor 1 like
Crk CRK proto-oncogene, adaptor protein
Flt1 Fms related receptor tyrosine kinase 1
Cnr2 cannabinoid receptor 2
Map2k2 mitogen activated protein kinase kinase 2
Slc30a1 solute carrier family 30 member 1
Twist2 twist family bHLH transcription factor 2
Mapk12 mitogen-activated protein kinase 12
Kitlg KIT ligand
Pik3r3 phosphoinositide-3-kinase regulatory subunit 3
Adgrl4 adhesion G protein-coupled receptor L4
Cap1 cyclase associated actin cytoskeleton regulatory protein 1
Pfn1 profilin 1
Cdc42 cell division cycle 42
Adcy3 adenylate cyclase 3
Adcy5 adenylate cyclase 5
Rab2a RAB2A, member RAS oncogene family
Lpar3 lysophosphatidic acid receptor 3
Fgfr1 Fibroblast growth factor receptor 1
Mtpn myotrophin
Pdgfc platelet derived growth factor C
Lat linker for activation of T cells
Msn moesin
Gnaq G protein subunit alpha q
Prkch protein kinase C, eta
Rala RAS like proto-oncogene A
Actb actin, beta
Pard3 par-3 family cell polarity regulator
Adcy7 adenylate cyclase 7
Fgfr3 fibroblast growth factor receptor 3
Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Laptm5 lysosomal protein transmembrane 5
Tek TEK receptor tyrosine kinase
Angpt2 angiopoietin 2
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Vegfb vascular endothelial growth factor B
Pgf placental growth factor
Cdc42bpb CDC42 binding protein kinase beta
Flt4 Fms related receptor tyrosine kinase 4
Vegfc vascular endothelial growth factor C
Braf B-Raf proto-oncogene, serine/threonine kinase
Plce1 phospholipase C, epsilon 1
Rgs14 regulator of G-protein signaling 14
Ralb RAS like proto-oncogene B
Mapk1 mitogen activated protein kinase 1
Efna5 ephrin A5
Gpr176 G protein-coupled receptor 176
Rhoa ras homolog family member A
Septin2 septin 2
Tpm3 tropomyosin 3
Lcp2 lymphocyte cytosolic protein 2
Map2k1 mitogen activated protein kinase kinase 1
Efna3 ephrin A3
Sstr3 somatostatin receptor 3
Rap1b RAP1B, member of RAS oncogene family
Mk1 Mk1 protein
Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3
Adgrf5 adhesion G protein-coupled receptor F5
Nradd neurotrophin receptor associated death domain
Dock9 dedicator of cytokinesis 9
Fut11 fucosyltransferase 11
Skap1 src kinase associated phosphoprotein 1
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Hcls1 hematopoietic cell specific Lyn substrate 1
Actr2 actin related protein 2
Afap1l1 actin filament associated protein 1-like 1
Fhod1 formin homology 2 domain containing 1
Prkd2 protein kinase D2
Hras HRas proto-oncogene, GTPase
Ankrd50 ankyrin repeat domain 50
Vav3 vav guanine nucleotide exchange factor 3
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Tns1 tensin 1
Abi3 ABI family, member 3
Nrros negative regulator of reactive oxygen species
Tiam1 TIAM Rac1 associated GEF 1
Cyyr1 cysteine and tyrosine rich 1
Hvcn1 hydrogen voltage-gated channel 1
Orai2 ORAI calcium release-activated calcium modulator 2
Adgra3 adhesion G protein-coupled receptor A3
Adcy1 adenylate cyclase 1
Mmrn2 multimerin 2
S1pr3 sphingosine-1-phosphate receptor 3
Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein
Pard6g par-6 family cell polarity regulator gamma
Itgal integrin subunit alpha L
Fermt3 FERM domain containing kindlin 3
Itgb2 integrin subunit beta 2
Efna4 ephrin A4
Ngf nerve growth factor
Fnbp1l formin binding protein 1-like
Ctnnd1 catenin delta 1
Dll4 delta like canonical Notch ligand 4
Soga1 suppressor of glucose, autophagy associated 1
Tln1 talin 1
Prkd3 protein kinase D3
Rasgrp3 RAS guanyl releasing protein 3
Clec14a C-type lectin domain containing 14A
Ptprb protein tyrosine phosphatase, receptor type, B
Dennd3 DENN domain containing 3
Nckap1l NCK associated protein 1 like
Ptprk protein tyrosine phosphatase, receptor type, K
Vegfd vascular endothelial growth factor D
Cdr2l cerebellar degeneration-related protein 2-like
Enah ENAH, actin regulator
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Sipa1l2 signal-induced proliferation-associated 1 like 2
Vasp vasodilator-stimulated phosphoprotein
Relt RELT, TNF receptor
Sipa1 signal-induced proliferation-associated 1
Chmp4c charged multivesicular body protein 4C
Shb SH2 domain containing adaptor protein B
Mbd3 methyl-CpG binding domain protein 3
Rac1 Rac family small GTPase 1
Ncf2 neutrophil cytosolic factor 2
Kctd12 potassium channel tetramerization domain containing 12
Nkd1 NKD inhibitor of WNT signaling pathway 1
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Dock4 dedicator of cytokinesis 4
Rac2 Rac family small GTPase 2
Dock6 dedicator of cytokinesis 6
Arhgap30 Rho GTPase activating protein 30
Lpar2 lysophosphatidic acid receptor 2
Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein
Fyb1 FYN binding protein 1
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1
Mapk11 mitogen-activated protein kinase 11
Cnn2 calponin 2
Palld palladin, cytoskeletal associated protein
Symbol Function*
FLT1 fms related receptor tyrosine kinase 1
FGF2 fibroblast growth factor 2
VEGFA vascular endothelial growth factor A
CNTNAP1 contactin associated protein 1
ACTB actin beta
ITGB1 integrin subunit beta 1
FGF7 fibroblast growth factor 7
GNAO1 G protein subunit alpha o1
EGFR epidermal growth factor receptor
ATP6V0A1 ATPase H+ transporting V0 subunit a1
EPHA2 EPH receptor A2
CDH5 cadherin 5
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
ADCY3 adenylate cyclase 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
AFDN afadin, adherens junction formation factor
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
FYB1 FYN binding protein 1
SH3RF1 SH3 domain containing ring finger 1
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
ADCY7 adenylate cyclase 7
RASSF5 Ras association domain family member 5
TLN1 talin 1
LOC696306 T cell receptor beta variable 3-1
CRKL CRK like proto-oncogene, adaptor protein
RAC2 Rac family small GTPase 2
CYTH4 cytohesin 4
PDGFRA platelet derived growth factor receptor alpha
ANGPT1 angiopoietin 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
KDR kinase insert domain receptor
IGF1 insulin like growth factor 1
CALM1 calmodulin 1
MAPK1 mitogen-activated protein kinase 1
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
EGF epidermal growth factor
LOC698785 uncharacterized LOC698785
GNAI3 G protein subunit alpha i3
VEGFC vascular endothelial growth factor C
CD3D CD3d molecule
RGS14 regulator of G protein signaling 14
TMEM125 transmembrane protein 125
PDGFC platelet derived growth factor C
MAFF MAF bZIP transcription factor F
LCP2 lymphocyte cytosolic protein 2
ENAH ENAH actin regulator
TEAD1 TEA domain transcription factor 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
FAM149A family with sequence similarity 149 member A
PLCB2 phospholipase C beta 2
TIAM1 TIAM Rac1 associated GEF 1
LOC703029 immunoglobulin lambda-1 light chain-like
SHKBP1 SH3KBP1 binding protein 1
RALA RAS like proto-oncogene A
PARVA parvin alpha
GNAI2 G protein subunit alpha i2
RAPGEF3 Rap guanine nucleotide exchange factor 3
LAPTM5 lysosomal protein transmembrane 5
DOCK2 dedicator of cytokinesis 2
LAT linker for activation of T cells
RAPGEF2 Rap guanine nucleotide exchange factor 2
CAPZA1 capping actin protein of muscle Z-line subunit alpha 1
LOC705671 actin, cytoplasmic 2-like
GNAQ G protein subunit alpha q
NCKAP1L NCK associated protein 1 like
INSR insulin receptor
RHOA ras homolog family member A
PARD3 par-3 family cell polarity regulator
TES testin LIM domain protein
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
HIP1R huntingtin interacting protein 1 related
TEK TEK receptor tyrosine kinase
TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3
CDC42 cell division cycle 42
PDGFA platelet derived growth factor subunit A
ADORA2A adenosine A2a receptor
KRAS KRAS proto-oncogene, GTPase
ADCY6 adenylate cyclase 6
PTCHD4 patched domain containing 4
CLMP CXADR like membrane protein
IGF1R insulin like growth factor 1 receptor
STON2 stonin 2
P2RY1 purinergic receptor P2Y1
NRAS NRAS proto-oncogene, GTPase
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
SLC22A3 solute carrier family 22 member 3
PCBP1 poly(rC) binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
LUM lumican
ILK integrin linked kinase
MAP2K1 mitogen-activated protein kinase kinase 1
ITGB2 integrin subunit beta 2
PFN1 profilin 1
KANK3 KN motif and ankyrin repeat domains 3
MAPRE1 microtubule associated protein RP/EB family member 1
CSF1R colony stimulating factor 1 receptor
ITGAL integrin subunit alpha L
CLIP3 CAP-Gly domain containing linker protein 3
GP1BB glycoprotein Ib platelet subunit beta
CLIC4 chloride intracellular channel 4
PARVG parvin gamma
VEGFD vascular endothelial growth factor D
PTPRC protein tyrosine phosphatase receptor type C
FGFR3 fibroblast growth factor receptor 3
VAV2 vav guanine nucleotide exchange factor 2
ACTG1 actin gamma 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
ADCY4 adenylate cyclase 4
ITGA2B integrin subunit alpha 2b
ITGB5 integrin subunit beta 5
MAPK12 mitogen-activated protein kinase 12
MAPK11 mitogen-activated protein kinase 11
ADCY5 adenylate cyclase 5
FGFR2 fibroblast growth factor receptor 2
SIPA1 signal-induced proliferation-associated 1
VASP vasodilator stimulated phosphoprotein
LOC716034 signal-regulatory protein gamma
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
MAN2B1 mannosidase alpha class 2B member 1
CALM3 calmodulin 3
PRKD2 protein kinase D2
PRKD1 protein kinase D1
KREMEN1 kringle containing transmembrane protein 1
ITGB3 integrin subunit beta 3
EFNA1 ephrin A1
RAC1 Rac family small GTPase 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
RAP1B RAP1B, member of RAS oncogene family
ARHGAP30 Rho GTPase activating protein 30
MFSD2B major facilitator superfamily domain containing 2B
NCOA1 nuclear receptor coactivator 1
USHBP1 USH1 protein network component harmonin binding protein 1
RRAS RAS related
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
LPAR2 lysophosphatidic acid receptor 2
MAST3 microtubule associated serine/threonine kinase 3
GMIP GEM interacting protein
PPP1CA protein phosphatase 1 catalytic subunit alpha
CFL1 cofilin 1
FERMT3 FERM domain containing kindlin 3
VAV1 vav guanine nucleotide exchange factor 1
C12H2orf88 chromosome 12 C2orf88 homolog
DYNLRB1 dynein light chain roadblock-type 1
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
LOC106999340 immunoglobulin kappa light chain
LOC106999345 T cell receptor alpha variable 26-1-like
LOC114677059 uncharacterized LOC114677059
Symbol Function*
VWF von Willebrand factor
MET MET proto-oncogene, receptor tyrosine kinase
MAOA monoamine oxidase A
SCN5A sodium voltage-gated channel alpha subunit 5
KITLG KIT ligand
ACTB actin beta
ANGPT1 angiopoietin 1
EGF epidermal growth factor
ACTR3 actin related protein 3
TEK TEK receptor tyrosine kinase
ITGB2 integrin subunit beta 2
ITGB3 integrin subunit beta 3
ITGA2B integrin subunit alpha 2b
KIT KIT proto-oncogene, receptor tyrosine kinase
ADCY5 adenylate cyclase 5
VASP vasodilator stimulated phosphoprotein
GNAS GNAS complex locus
RHOA ras homolog family member A
EGFR epidermal growth factor receptor
FGFR2 fibroblast growth factor receptor 2
CDH1 cadherin 1
IGF1R insulin like growth factor 1 receptor
GNAI2 G protein subunit alpha i2
CCL21 C-C motif chemokine ligand 21
LPAR1 lysophosphatidic acid receptor 1
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
CAPZA1 capping actin protein of muscle Z-line subunit alpha 1
RALA RAS like proto-oncogene A
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
PLCB3 phospholipase C beta 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
LCP1 lymphocyte cytosolic protein 1
CTNNB1 catenin beta 1
MRAS muscle RAS oncogene homolog
PLCB4 phospholipase C beta 4
FGF9 fibroblast growth factor 9
MAPK1 mitogen-activated protein kinase 1
PARD3 par-3 family cell polarity regulator
NRP1 neuropilin 1
ITGB1 integrin subunit beta 1
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
TLN2 talin 2
DYNC1I2 dynein cytoplasmic 1 intermediate chain 2
FYB1 FYN binding protein 1
PDGFD platelet derived growth factor D
YAP1 Yes1 associated transcriptional regulator
PRKCZ protein kinase C zeta
BCAR1 BCAR1 scaffold protein, Cas family member
VAV3 vav guanine nucleotide exchange factor 3
ARHGAP29 Rho GTPase activating protein 29
ADCY4 adenylate cyclase 4
SIPA1L1 signal induced proliferation associated 1 like 1
CALM1 calmodulin 1
CA4 carbonic anhydrase 4
GPM6B glycoprotein M6B
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
RAC2 Rac family small GTPase 2
FLT4 fms related receptor tyrosine kinase 4
KDR kinase insert domain receptor
DOCK4 dedicator of cytokinesis 4
ZYX zyxin
VEGFC vascular endothelial growth factor C
PRKD3 protein kinase D3
RAP1A RAP1A, member of RAS oncogene family
CTNND1 catenin delta 1
GRK2 G protein-coupled receptor kinase 2
SIPA1 signal-induced proliferation-associated 1
EHBP1L1 EH domain binding protein 1 like 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
RALB RAS like proto-oncogene B
PARD6G par-6 family cell polarity regulator gamma
GP6 glycoprotein VI platelet
CD37 CD37 molecule
RASIP1 Ras interacting protein 1
PRKD2 protein kinase D2
FKBP8 FKBP prolyl isomerase 8
F2RL3 F2R like thrombin or trypsin receptor 3
INSR insulin receptor
VAV1 vav guanine nucleotide exchange factor 1
NUMA1 nuclear mitotic apparatus protein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
PARD6B par-6 family cell polarity regulator beta
FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2
SNAP29 synaptosome associated protein 29
BIN2 bridging integrator 2
RAPGEF3 Rap guanine nucleotide exchange factor 3
PLCE1 phospholipase C epsilon 1
TRIM8 tripartite motif containing 8
CALML5 calmodulin like 5
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
KIFC3 kinesin family member C3
ADCY7 adenylate cyclase 7
LOC487387 RAP1 GTPase activating protein
EPHA2 EPH receptor A2
NEO1 neogenin 1
TIAM1 TIAM Rac1 associated GEF 1
RAPGEF4 Rap guanine nucleotide exchange factor 4
FGFR3 fibroblast growth factor receptor 3
SIPA1L2 signal induced proliferation associated 1 like 2
LCP2 lymphocyte cytosolic protein 2
NDST1 N-deacetylase and N-sulfotransferase 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
LOC489647 cadherin-1-like
COTL1 coactosin like F-actin binding protein 1
ITGAL integrin subunit alpha L
CORO1A coronin 1A
PRKCB protein kinase C beta
ADCY9 adenylate cyclase 9
RHBDL1 rhomboid like 1
MAPKAPK2 MAPK activated protein kinase 2
ENAH ENAH actin regulator
EFNA1 ephrin A1
EFNA4 ephrin A4
DSG2 desmoglein 2
CDC42BPB CDC42 binding protein kinase beta
AKT1 AKT serine/threonine kinase 1
RAPGEF1 Rap guanine nucleotide exchange factor 1
PDGFA platelet derived growth factor subunit A
VEGFD vascular endothelial growth factor D
MAPK12 mitogen-activated protein kinase 12
PFN1 profilin 1
ANGPT2 angiopoietin 2
LAT linker for activation of T cells
VAV2 vav guanine nucleotide exchange factor 2
CRKL CRK like proto-oncogene, adaptor protein
PRKD1 protein kinase D1
GNAO1 G protein subunit alpha o1
ID1 inhibitor of DNA binding 1, HLH protein
EMCN endomucin
SLC66A3 solute carrier family 66 member 3
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
PECAM1 platelet and endothelial cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
RASGRP3 RAS guanyl releasing protein 3
CSF1 colony stimulating factor 1
GNAI3 G protein subunit alpha i3
SLC25A24 solute carrier family 25 member 24
MAP2K2 mitogen-activated protein kinase kinase 2
RASGRP2 RAS guanyl releasing protein 2
FGF10 fibroblast growth factor 10
SIPA1L3 signal induced proliferation associated 1 like 3
MAPK13 mitogen-activated protein kinase 13
CRK CRK proto-oncogene, adaptor protein
ZBTB47 zinc finger and BTB domain containing 47
DENND1C DENN domain containing 1C
CD53 CD53 molecule
PLCB2 phospholipase C beta 2
TLN1 talin 1
FGFR1 fibroblast growth factor receptor 1
LIMD1 LIM domain containing 1
EFNA3 ephrin A3
LOC102153034 calmodulin-like protein 3
TSHZ2 teashirt zinc finger homeobox 2
RAC3 Rac family small GTPase 3
STUM stum, mechanosensory transduction mediator homolog
LOC119863905 mastermind like transcriptional coactivator 3
LOC119865433 uncharacterized LOC119865433
ELMO2 engulfment and cell motility 2
BTK Bruton tyrosine kinase
Symbol Function*
MET MET proto-oncogene, receptor tyrosine kinase
HGF hepatocyte growth factor
CSF1R colony stimulating factor 1 receptor
KIT KIT proto-oncogene, receptor tyrosine kinase
HRAS HRas proto-oncogene, GTPase
ITGB1 integrin subunit beta 1
BCL2L2 BCL2 like 2
INSR insulin receptor
FGF2 fibroblast growth factor 2
PDGFB platelet derived growth factor subunit B
ACTG1 actin gamma 1
NGF nerve growth factor
TUBB1 tubulin beta 1 class VI
IGF1R insulin like growth factor 1 receptor
EGFR epidermal growth factor receptor
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AFDN afadin, adherens junction formation factor
MAP2K1 mitogen-activated protein kinase kinase 1
MS4A10 membrane spanning 4-domains A10
CDK14 cyclin dependent kinase 14
SHROOM4 shroom family member 4
MAP2K3 mitogen-activated protein kinase kinase 3
FLNA filamin A
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
DOCK4 dedicator of cytokinesis 4
MYH10 myosin heavy chain 10
AVIL advillin
ARHGEF1 Rho guanine nucleotide exchange factor 1
STX12 syntaxin 12
CD53 CD53 molecule
CNN2 calponin 2
PDGFRB platelet derived growth factor receptor beta
ARPC1B actin related protein 2/3 complex subunit 1B
TNS1 tensin 1
VGLL3 vestigial like family member 3
CRKL CRK like proto-oncogene, adaptor protein
RAPGEF2 Rap guanine nucleotide exchange factor 2
PDGFD platelet derived growth factor D
ENAH ENAH actin regulator
RASGRP3 RAS guanyl releasing protein 3
ITGAL integrin subunit alpha L
EFNA5 ephrin A5
CLEC1A C-type lectin domain family 1 member A
FGFR1 fibroblast growth factor receptor 1
CRK CRK proto-oncogene, adaptor protein
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
LIX1L limb and CNS expressed 1 like
FMNL1 formin like 1
ANGPT1 angiopoietin 1
ITGB2 integrin subunit beta 2
SHROOM2 shroom family member 2
MAPK1 mitogen-activated protein kinase 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F
AKT1 AKT serine/threonine kinase 1
SELPLG selectin P ligand
LOC101087957 integrin alpha-M
MAPK3 mitogen-activated protein kinase 3
TRIM72 tripartite motif containing 72
PLD4 phospholipase D family member 4
SLC35G1 solute carrier family 35 member G1
RAPGEF5 Rap guanine nucleotide exchange factor 5
NAPA NSF attachment protein alpha
PDGFC platelet derived growth factor C
PRKCB protein kinase C beta
CD244 CD244 molecule
FKBP10 FKBP prolyl isomerase 10
LY9 lymphocyte antigen 9
SIPA1L2 signal induced proliferation associated 1 like 2
MTMR3 myotubularin related protein 3
RASSF5 Ras association domain family member 5
GNAI2 G protein subunit alpha i2
CD48 CD48 molecule
NUDT6 nudix hydrolase 6
SERINC5 serine incorporator 5
KDR kinase insert domain receptor
ETS1 ETS proto-oncogene 1, transcription factor
FGF10 fibroblast growth factor 10
RASAL3 RAS protein activator like 3
FGF17 fibroblast growth factor 17
PDGFRA platelet derived growth factor receptor alpha
TRIM16 tripartite motif containing 16
MAPKAPK2 MAPK activated protein kinase 2
PLCB2 phospholipase C beta 2
RALA RAS like proto-oncogene A
CALM3 calmodulin 3
ADCY6 adenylate cyclase 6
ANGPT4 angiopoietin 4
LOC101091541 phosphatidylinositol phosphatase PTPRQ
GNL1 G protein nucleolar 1 (putative)
PFN1 profilin 1
TEK TEK receptor tyrosine kinase
ITGB3 integrin subunit beta 3
LOC101092190 ribonuclease K3
PLCB1 phospholipase C beta 1
SEMA5B semaphorin 5B
AKT3 AKT serine/threonine kinase 3
GNAI1 G protein subunit alpha i1
RAPGEF4 Rap guanine nucleotide exchange factor 4
PLCB3 phospholipase C beta 3
TLN1 talin 1
CC2D2A coiled-coil and C2 domain containing 2A
PIK3R3 phosphoinositide-3-kinase regulatory subunit 3
SORBS2 sorbin and SH3 domain containing 2
UCHL1 ubiquitin C-terminal hydrolase L1
FZD4 frizzled class receptor 4
RAP1GAP RAP1 GTPase activating protein
ADCY7 adenylate cyclase 7
PODXL podocalyxin like
LIMS1 LIM zinc finger domain containing 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
NCKAP1L NCK associated protein 1 like
RASGRP2 RAS guanyl releasing protein 2
CALM1 calmodulin 1
VASP vasodilator stimulated phosphoprotein
FGFR2 fibroblast growth factor receptor 2
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3
CALD1 caldesmon 1
PGF placental growth factor
RAP1B RAP1B, member of RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
LOC101096188 sialic acid-binding Ig-like lectin 5
RAC2 Rac family small GTPase 2
NCKAP1 NCK associated protein 1
LCP2 lymphocyte cytosolic protein 2
VAV1 vav guanine nucleotide exchange factor 1
CTNNB1 catenin beta 1
PRKG1 protein kinase cGMP-dependent 1
KANK2 KN motif and ankyrin repeat domains 2
PKN1 protein kinase N1
LARP6 La ribonucleoprotein 6, translational regulator
FGF7 fibroblast growth factor 7
LPAR3 lysophosphatidic acid receptor 3
MTMR1 myotubularin related protein 1
STK10 serine/threonine kinase 10
ADGRE3 adhesion G protein-coupled receptor E3
ACTB actin beta
SIPA1 signal-induced proliferation-associated 1
RGS14 regulator of G protein signaling 14
IRAG2 inositol 1,4,5-triphosphate receptor associated 2
RAPGEF1 Rap guanine nucleotide exchange factor 1
PFN2 profilin 2
CALML4 calmodulin like 4
CFL1 cofilin 1
MAP2K2 mitogen-activated protein kinase kinase 2
PLEKHG1 pleckstrin homology and RhoGEF domain containing G1
ADCY5 adenylate cyclase 5
F2R coagulation factor II thrombin receptor
PRKD3 protein kinase D3
ITGA2B integrin subunit alpha 2b
RAC1 Rac family small GTPase 1
ADGRF5 adhesion G protein-coupled receptor F5
NGFR nerve growth factor receptor
PARD6A par-6 family cell polarity regulator alpha
ANGPT2 angiopoietin 2
LOC102902292 uncharacterized LOC102902292
IKBIP IKBKB interacting protein
PARD6G par-6 family cell polarity regulator gamma
NRARP NOTCH regulated ankyrin repeat protein
LOC109494706 uncharacterized LOC109494706
LOC109495407 uncharacterized LOC109495407
LOC111556187 calmodulin-like protein 4
MSANTD3 Myb/SANT DNA binding domain containing 3
EFNA2 ephrin A2


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