[←][→] hsa  ADCY7 Gene
functional annotation
Function   adenylate cyclase 7  
GO BP
GO:0006171 [list] [network] cAMP biosynthetic process  (10 genes)  IDA  
GO:0071285 [list] [network] cellular response to lithium ion  (14 genes)  ISS  
GO:0071361 [list] [network] cellular response to ethanol  (16 genes)  IDA  
GO:0034199 [list] [network] activation of protein kinase A activity  (18 genes)  TAS  
GO:0071377 [list] [network] cellular response to glucagon stimulus  (27 genes)  TAS  
GO:0003091 [list] [network] renal water homeostasis  (36 genes)  TAS  
GO:1900016 [list] [network] negative regulation of cytokine production involved in inflammatory response  (36 genes)  ISS  
GO:0007190 [list] [network] activation of adenylate cyclase activity  (41 genes)  TAS  
GO:0060135 [list] [network] maternal process involved in female pregnancy  (62 genes)  IEA  
GO:0007193 [list] [network] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (83 genes)  TAS  
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway  (132 genes)  IBA TAS  
GO:0002819 [list] [network] regulation of adaptive immune response  (183 genes)  ISS  
GO:0002862 [list] [network] negative regulation of inflammatory response to antigenic stimulus  (208 genes)  TAS  
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway  (1290 genes)  TAS  
GO:0035556 [list] [network] intracellular signal transduction  (1640 genes)  IEA  
GO CC
GO:0005887 [list] [network] integral component of plasma membrane  (1649 genes)  IBA  
GO:0016021 [list] [network] integral component of membrane  (5388 genes)  IDA  
GO:0005886 [list] [network] plasma membrane  (5772 genes)  ISS TAS  
GO MF
GO:0004016 [list] [network] adenylate cyclase activity  (11 genes)  IBA IDA IMP  
GO:0005524 [list] [network] ATP binding  (1474 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (4237 genes)  IEA  
KEGG hsa00230 [list] [network] Purine metabolism (126 genes)
hsa01522 [list] [network] Endocrine resistance (98 genes)
hsa04015 [list] [network] Rap1 signaling pathway (210 genes)
hsa04020 [list] [network] Calcium signaling pathway (240 genes)
hsa04022 [list] [network] cGMP-PKG signaling pathway (167 genes)
hsa04024 [list] [network] cAMP signaling pathway (221 genes)
hsa04062 [list] [network] Chemokine signaling pathway (192 genes)
hsa04072 [list] [network] Phospholipase D signaling pathway (148 genes)
hsa04114 [list] [network] Oocyte meiosis (131 genes)
hsa04211 [list] [network] Longevity regulating pathway (89 genes)
hsa04213 [list] [network] Longevity regulating pathway - multiple species (62 genes)
hsa04261 [list] [network] Adrenergic signaling in cardiomyocytes (150 genes)
hsa04270 [list] [network] Vascular smooth muscle contraction (134 genes)
hsa04371 [list] [network] Apelin signaling pathway (139 genes)
hsa04540 [list] [network] Gap junction (88 genes)
hsa04611 [list] [network] Platelet activation (124 genes)
hsa04713 [list] [network] Circadian entrainment (97 genes)
hsa04714 [list] [network] Thermogenesis (232 genes)
hsa04723 [list] [network] Retrograde endocannabinoid signaling (148 genes)
hsa04724 [list] [network] Glutamatergic synapse (114 genes)
hsa04725 [list] [network] Cholinergic synapse (113 genes)
hsa04727 [list] [network] GABAergic synapse (89 genes)
hsa04750 [list] [network] Inflammatory mediator regulation of TRP channels (98 genes)
hsa04911 [list] [network] Insulin secretion (86 genes)
hsa04912 [list] [network] GnRH signaling pathway (93 genes)
hsa04913 [list] [network] Ovarian steroidogenesis (51 genes)
hsa04914 [list] [network] Progesterone-mediated oocyte maturation (102 genes)
hsa04915 [list] [network] Estrogen signaling pathway (138 genes)
hsa04916 [list] [network] Melanogenesis (101 genes)
hsa04918 [list] [network] Thyroid hormone synthesis (75 genes)
hsa04921 [list] [network] Oxytocin signaling pathway (154 genes)
hsa04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes)
hsa04925 [list] [network] Aldosterone synthesis and secretion (98 genes)
hsa04926 [list] [network] Relaxin signaling pathway (129 genes)
hsa04927 [list] [network] Cortisol synthesis and secretion (65 genes)
hsa04928 [list] [network] Parathyroid hormone synthesis, secretion and action (106 genes)
hsa04934 [list] [network] Cushing syndrome (155 genes)
hsa04935 [list] [network] Growth hormone synthesis, secretion and action (119 genes)
hsa04970 [list] [network] Salivary secretion (93 genes)
hsa04971 [list] [network] Gastric acid secretion (76 genes)
hsa04972 [list] [network] Pancreatic secretion (102 genes)
hsa04976 [list] [network] Bile secretion (89 genes)
hsa05032 [list] [network] Morphine addiction (91 genes)
hsa05163 [list] [network] Human cytomegalovirus infection (225 genes)
hsa05166 [list] [network] Human T-cell leukemia virus 1 infection (222 genes)
hsa05200 [list] [network] Pathways in cancer (531 genes)
hsa05207 [list] [network] Chemical carcinogenesis - receptor activation (212 genes)
hsa05414 [list] [network] Dilated cardiomyopathy (96 genes)
Protein NP_001105.1  NP_001272986.1  XP_011521137.1  XP_011521138.1  XP_011521139.1  XP_011521140.1  XP_011521141.1  XP_011521142.1  XP_011521144.1  XP_016878385.1  XP_016878386.1  XP_016878387.1  XP_016878388.1 
BLAST NP_001105.1  NP_001272986.1  XP_011521137.1  XP_011521138.1  XP_011521139.1  XP_011521140.1  XP_011521141.1  XP_011521142.1  XP_011521144.1  XP_016878385.1  XP_016878386.1  XP_016878387.1  XP_016878388.1 
Orthologous [Ortholog page] ADCY2 (hsa)  Adcy7 (mmu)  Ac76E (dme)  Adcy2 (rno)  Adcy7 (rno)  acy-2 (cel)  Adcy2 (mmu)  ADCY7 (gga)  ADCY2 (gga)  ADCY2 (cfa)  ADCY7 (cfa)  adcy2b (dre)  adcy2a (dre)  adcy7 (dre)  ADCY7 (mcc)  ADCY2 (mcc)  ADCY7 (fca)  ADCY2 (fca) 
Subcellular
localization
wolf
plas 10  (predict for NP_001105.1)
plas 10  (predict for NP_001272986.1)
plas 10  (predict for XP_011521137.1)
plas 10  (predict for XP_011521138.1)
plas 10  (predict for XP_011521139.1)
plas 10  (predict for XP_011521140.1)
plas 10  (predict for XP_011521141.1)
plas 10  (predict for XP_011521142.1)
plas 10  (predict for XP_011521144.1)
plas 9  (predict for XP_016878385.1)
plas 9  (predict for XP_016878386.1)
plas 10  (predict for XP_016878387.1)
plas 10  (predict for XP_016878388.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05200 Pathways in cancer 3
hsa04020 Calcium signaling pathway 3
hsa04611 Platelet activation 3
hsa04621 NOD-like receptor signaling pathway 3
hsa04750 Inflammatory mediator regulation of TRP channels 3
Genes directly connected with ADCY7 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.0 PLCB2 phospholipase C beta 2 [detail] 0 5330
5.6 TRPV2 transient receptor potential cation channel subfamily V member 2 [detail] 0 51393
5.3 NLRP1 NLR family pyrin domain containing 1 [detail] 0 22861
5.2 RIN3 Ras and Rab interactor 3 [detail] 0 79890
Coexpressed
gene list		 [Coexpressed gene list for ADCY7]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 113      
Refseq ID (protein) NP_001105.1 
NP_001272986.1 
XP_011521137.1 
XP_011521138.1 
XP_011521139.1 
XP_011521140.1 
XP_011521141.1 
XP_011521142.1 
XP_011521144.1 
XP_016878385.1 
XP_016878386.1 
XP_016878387.1 
XP_016878388.1 


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