| functional annotation |
| Function |
adenylate cyclase 4 |
|
| GO BP |
|
GO:0006171 [list] [network] cAMP biosynthetic process
|
(11 genes)
|
ISO
TAS
|
 |
|
GO:0007190 [list] [network] activation of adenylate cyclase activity
|
(23 genes)
|
TAS
|
|
|
GO:0009190 [list] [network] cyclic nucleotide biosynthetic process
|
(24 genes)
|
IEA
|
|
|
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway
|
(128 genes)
|
IBA
|
|
|
GO:0007188 [list] [network] adenylate cyclase-modulating G protein-coupled receptor signaling pathway
|
(203 genes)
|
IDA
|
|
|
GO:0035556 [list] [network] intracellular signal transduction
|
(1356 genes)
|
ISO
|
|
|
| GO CC |
|
GO:0030425 [list] [network] dendrite
|
(740 genes)
|
IDA
|
|
|
GO:0005887 [list] [network] integral component of plasma membrane
|
(1555 genes)
|
IBA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5442 genes)
|
TAS
|
|
|
GO:0032991 [list] [network] protein-containing complex
|
(5540 genes)
|
ISO
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(5954 genes)
|
IEA
|
|
|
GO:0005634 [list] [network] nucleus
|
(7226 genes)
|
ISO
|
|
|
GO:0016020 [list] [network] membrane
|
(9571 genes)
|
ISO
|
|
|
GO:0005737 [list] [network] cytoplasm
|
(11434 genes)
|
ISO
|
|
|
GO:0005622 [list] [network] intracellular anatomical structure
|
(14259 genes)
|
IDA
|
|
|
| GO MF |
|
GO:0004016 [list] [network] adenylate cyclase activity
|
(12 genes)
|
IBA
ISO
TAS
|
|
|
GO:0031683 [list] [network] G-protein beta/gamma-subunit complex binding
|
(24 genes)
|
ISO
|
|
|
GO:0016849 [list] [network] phosphorus-oxygen lyase activity
|
(25 genes)
|
IEA
|
|
|
GO:0005080 [list] [network] protein kinase C binding
|
(64 genes)
|
ISO
|
|
|
GO:0016829 [list] [network] lyase activity
|
(196 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1396 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2052 genes)
|
IEA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(3573 genes)
|
IEA
|
|
|
| KEGG |
mmu00230 [list] [network] Purine metabolism (133 genes) |
 |
| mmu01522 [list] [network] Endocrine resistance (93 genes) |
|
| mmu04015 [list] [network] Rap1 signaling pathway (214 genes) |
|
| mmu04020 [list] [network] Calcium signaling pathway (240 genes) |
|
| mmu04022 [list] [network] cGMP-PKG signaling pathway (173 genes) |
|
| mmu04024 [list] [network] cAMP signaling pathway (220 genes) |
|
| mmu04062 [list] [network] Chemokine signaling pathway (192 genes) |
|
| mmu04072 [list] [network] Phospholipase D signaling pathway (149 genes) |
|
| mmu04114 [list] [network] Oocyte meiosis (121 genes) |
|
| mmu04211 [list] [network] Longevity regulating pathway (90 genes) |
|
| mmu04213 [list] [network] Longevity regulating pathway - multiple species (62 genes) |
|
| mmu04261 [list] [network] Adrenergic signaling in cardiomyocytes (152 genes) |
|
| mmu04270 [list] [network] Vascular smooth muscle contraction (144 genes) |
|
| mmu04371 [list] [network] Apelin signaling pathway (137 genes) |
|
| mmu04540 [list] [network] Gap junction (86 genes) |
|
| mmu04611 [list] [network] Platelet activation (124 genes) |
|
| mmu04713 [list] [network] Circadian entrainment (98 genes) |
|
| mmu04714 [list] [network] Thermogenesis (231 genes) |
|
| mmu04723 [list] [network] Retrograde endocannabinoid signaling (148 genes) |
|
| mmu04724 [list] [network] Glutamatergic synapse (113 genes) |
|
| mmu04725 [list] [network] Cholinergic synapse (112 genes) |
|
| mmu04727 [list] [network] GABAergic synapse (89 genes) |
|
| mmu04742 [list] [network] Taste transduction (92 genes) |
|
| mmu04750 [list] [network] Inflammatory mediator regulation of TRP channels (127 genes) |
|
| mmu04911 [list] [network] Insulin secretion (86 genes) |
|
| mmu04912 [list] [network] GnRH signaling pathway (90 genes) |
|
| mmu04913 [list] [network] Ovarian steroidogenesis (63 genes) |
|
| mmu04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes) |
|
| mmu04915 [list] [network] Estrogen signaling pathway (134 genes) |
|
| mmu04916 [list] [network] Melanogenesis (100 genes) |
|
| mmu04918 [list] [network] Thyroid hormone synthesis (74 genes) |
|
| mmu04921 [list] [network] Oxytocin signaling pathway (153 genes) |
|
| mmu04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes) |
|
| mmu04925 [list] [network] Aldosterone synthesis and secretion (102 genes) |
|
| mmu04926 [list] [network] Relaxin signaling pathway (129 genes) |
|
| mmu04927 [list] [network] Cortisol synthesis and secretion (72 genes) |
|
| mmu04928 [list] [network] Parathyroid hormone synthesis, secretion and action (108 genes) |
|
| mmu04934 [list] [network] Cushing syndrome (162 genes) |
|
| mmu04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes) |
|
| mmu04970 [list] [network] Salivary secretion (86 genes) |
|
| mmu04971 [list] [network] Gastric acid secretion (75 genes) |
|
| mmu04972 [list] [network] Pancreatic secretion (114 genes) |
|
| mmu04976 [list] [network] Bile secretion (100 genes) |
|
| mmu05032 [list] [network] Morphine addiction (91 genes) |
|
| mmu05163 [list] [network] Human cytomegalovirus infection (256 genes) |
|
| mmu05166 [list] [network] Human T-cell leukemia virus 1 infection (250 genes) |
|
| mmu05200 [list] [network] Pathways in cancer (543 genes) |
|
| mmu05207 [list] [network] Chemical carcinogenesis - receptor activation (225 genes) |
|
| mmu05414 [list] [network] Dilated cardiomyopathy (94 genes) |
|
| Protein |
NP_001348533.1
NP_536683.1
XP_006518387.1
XP_006518388.1
XP_006518389.1
XP_036014230.1
|
| BLAST |
NP_001348533.1
NP_536683.1
XP_006518387.1
XP_006518388.1
XP_006518389.1
XP_036014230.1
|
| Orthologous |
[Ortholog page]
Adcy4 (rno)
ADCY4 (hsa)
ADCY4 (cfa)
ADCY4 (mcc)
ADCY4 (fca)
|
Subcellular
localization
wolf |
|
plas 10
|
(predict for NP_001348533.1)
|
|
plas 10
|
(predict for NP_536683.1)
|
|
plas 10
|
(predict for XP_006518387.1)
|
|
plas 10
|
(predict for XP_006518388.1)
|
|
plas 10
|
(predict for XP_006518389.1)
|
|
plas 9,
nucl 0,
cyto_nucl 0
|
(predict for XP_036014230.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu04514 |
Cell adhesion molecules |
2 |
 |
| mmu04670 |
Leukocyte transendothelial migration |
2 |
 |
| mmu04015 |
Rap1 signaling pathway |
2 |
 |
| mmu04151 |
PI3K-Akt signaling pathway |
2 |
 |
Genes directly connected with Adcy4 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 11.3 |
Tie1 |
tyrosine kinase with immunoglobulin-like and EGF-like domains 1 |
[detail] |
0 |
21846 |
| 10.8 |
Arhgef15 |
Rho guanine nucleotide exchange factor (GEF) 15 |
[detail] |
0 |
442801 |
| 10.2 |
Mmrn2 |
multimerin 2 |
[detail] |
0 |
105450 |
| 9.7 |
Hspa12b |
heat shock protein 12B |
[detail] |
0 |
72630 |
| 8.6 |
Acvrl1 |
activin A receptor, type II-like 1 |
[detail] |
0 |
11482 |
| 7.9 |
Gpr4 |
G protein-coupled receptor 4 |
[detail] |
0 |
319197 |
| 7.3 |
Slc9a3r2 |
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 |
[detail] |
0 |
65962 |
| 6.4 |
Gja5 |
gap junction protein, alpha 5 |
[detail] |
0 |
14613 |
| 6.0 |
Pkn3 |
protein kinase N3 |
[detail] |
0 |
263803 |
| 5.7 |
Lrrc32 |
leucine rich repeat containing 32 |
[detail] |
0 |
434215 |
| 5.5 |
Arhgap31 |
Rho GTPase activating protein 31 |
[detail] |
0 |
12549 |
| 5.3 |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
[detail] |
0 |
56532 |
|
Coexpressed
gene list |
[Coexpressed gene list for Adcy4]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Adcy4 Gene
