| functional annotation |
| Function |
adenylate cyclase 5 |
|
| GO BP |
|
GO:0007195 [list] [network] adenylate cyclase-inhibiting dopamine receptor signaling pathway
|
(5 genes)
|
IEA
ISO
|
 |
|
GO:0001973 [list] [network] G protein-coupled adenosine receptor signaling pathway
|
(10 genes)
|
IEA
ISO
|
|
|
GO:0006171 [list] [network] cAMP biosynthetic process
|
(10 genes)
|
IBA
IDA
IEA
ISO
|
|
|
GO:0007191 [list] [network] adenylate cyclase-activating dopamine receptor signaling pathway
|
(10 genes)
|
IEA
ISO
|
|
|
GO:1904322 [list] [network] cellular response to forskolin
|
(57 genes)
|
IEA
ISO
ISS
|
|
|
GO:0043278 [list] [network] response to morphine
|
(59 genes)
|
IEP
|
|
|
GO:0050885 [list] [network] neuromuscular process controlling balance
|
(69 genes)
|
IEA
ISO
|
|
|
GO:0007193 [list] [network] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
|
(73 genes)
|
IBA
|
|
|
GO:0061178 [list] [network] regulation of insulin secretion involved in cellular response to glucose stimulus
|
(91 genes)
|
IEA
ISO
ISS
|
|
|
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway
|
(132 genes)
|
IBA
IMP
ISO
ISS
|
|
|
GO:0010977 [list] [network] negative regulation of neuron projection development
|
(169 genes)
|
IMP
|
|
|
GO:0007626 [list] [network] locomotory behavior
|
(250 genes)
|
IEA
ISO
|
|
|
GO:0007204 [list] [network] positive regulation of cytosolic calcium ion concentration
|
(320 genes)
|
IEA
ISO
ISS
|
|
|
GO:0007568 [list] [network] aging
|
(500 genes)
|
IEP
|
|
|
GO:0007507 [list] [network] heart development
|
(631 genes)
|
IEP
|
|
|
GO:0007420 [list] [network] brain development
|
(960 genes)
|
IEP
|
|
|
GO:0035556 [list] [network] intracellular signal transduction
|
(1357 genes)
|
IEA
|
|
|
| GO CC |
|
GO:0042383 [list] [network] sarcolemma
|
(175 genes)
|
IDA
|
|
|
GO:0045111 [list] [network] intermediate filament cytoskeleton
|
(185 genes)
|
IEA
ISO
|
|
|
GO:0045121 [list] [network] membrane raft
|
(407 genes)
|
IDA
|
|
|
GO:0005929 [list] [network] cilium
|
(680 genes)
|
IEA
ISO
ISS
|
|
|
GO:0005768 [list] [network] endosome
|
(855 genes)
|
IDA
|
|
|
GO:0005887 [list] [network] integral component of plasma membrane
|
(1281 genes)
|
IBA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5814 genes)
|
IDA
IEA
ISO
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(6265 genes)
|
IEA
ISO
ISS
|
|
|
GO:0016020 [list] [network] membrane
|
(9382 genes)
|
ISO
|
|
|
| GO MF |
|
GO:0008294 [list] [network] calcium- and calmodulin-responsive adenylate cyclase activity
|
(5 genes)
|
IDA
|
|
|
GO:0004016 [list] [network] adenylate cyclase activity
|
(12 genes)
|
IBA
IDA
IEA
ISO
|
|
|
GO:0008179 [list] [network] adenylate cyclase binding
|
(15 genes)
|
IEA
ISO
|
|
|
GO:0097110 [list] [network] scaffold protein binding
|
(78 genes)
|
IEA
ISO
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1380 genes)
|
IEA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(3303 genes)
|
IEA
|
|
|
| KEGG |
rno00230 [list] [network] Purine metabolism (130 genes) |
 |
| rno01522 [list] [network] Endocrine resistance (94 genes) |
|
| rno04015 [list] [network] Rap1 signaling pathway (213 genes) |
|
| rno04022 [list] [network] cGMP-PKG signaling pathway (171 genes) |
|
| rno04024 [list] [network] cAMP signaling pathway (217 genes) |
|
| rno04062 [list] [network] Chemokine signaling pathway (182 genes) |
|
| rno04072 [list] [network] Phospholipase D signaling pathway (150 genes) |
|
| rno04114 [list] [network] Oocyte meiosis (120 genes) |
|
| rno04211 [list] [network] Longevity regulating pathway (90 genes) |
|
| rno04213 [list] [network] Longevity regulating pathway - multiple species (64 genes) |
|
| rno04261 [list] [network] Adrenergic signaling in cardiomyocytes (148 genes) |
|
| rno04270 [list] [network] Vascular smooth muscle contraction (139 genes) |
|
| rno04371 [list] [network] Apelin signaling pathway (137 genes) |
|
| rno04540 [list] [network] Gap junction (87 genes) |
|
| rno04611 [list] [network] Platelet activation (126 genes) |
|
| rno04713 [list] [network] Circadian entrainment (98 genes) |
|
| rno04714 [list] [network] Thermogenesis (237 genes) |
|
| rno04723 [list] [network] Retrograde endocannabinoid signaling (151 genes) |
|
| rno04724 [list] [network] Glutamatergic synapse (114 genes) |
|
| rno04725 [list] [network] Cholinergic synapse (113 genes) |
|
| rno04726 [list] [network] Serotonergic synapse (123 genes) |
|
| rno04727 [list] [network] GABAergic synapse (91 genes) |
|
| rno04728 [list] [network] Dopaminergic synapse (132 genes) |
|
| rno04750 [list] [network] Inflammatory mediator regulation of TRP channels (115 genes) |
|
| rno04911 [list] [network] Insulin secretion (85 genes) |
|
| rno04912 [list] [network] GnRH signaling pathway (90 genes) |
|
| rno04913 [list] [network] Ovarian steroidogenesis (58 genes) |
|
| rno04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes) |
|
| rno04915 [list] [network] Estrogen signaling pathway (135 genes) |
|
| rno04916 [list] [network] Melanogenesis (99 genes) |
|
| rno04918 [list] [network] Thyroid hormone synthesis (73 genes) |
|
| rno04921 [list] [network] Oxytocin signaling pathway (155 genes) |
|
| rno04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes) |
|
| rno04924 [list] [network] Renin secretion (72 genes) |
|
| rno04925 [list] [network] Aldosterone synthesis and secretion (96 genes) |
|
| rno04926 [list] [network] Relaxin signaling pathway (128 genes) |
|
| rno04927 [list] [network] Cortisol synthesis and secretion (68 genes) |
|
| rno04928 [list] [network] Parathyroid hormone synthesis, secretion and action (105 genes) |
|
| rno04934 [list] [network] Cushing syndrome (158 genes) |
|
| rno04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes) |
|
| rno04970 [list] [network] Salivary secretion (81 genes) |
|
| rno04971 [list] [network] Gastric acid secretion (75 genes) |
|
| rno04972 [list] [network] Pancreatic secretion (105 genes) |
|
| rno04976 [list] [network] Bile secretion (94 genes) |
|
| rno05012 [list] [network] Parkinson disease (270 genes) |
|
| rno05030 [list] [network] Cocaine addiction (47 genes) |
|
| rno05031 [list] [network] Amphetamine addiction (68 genes) |
|
| rno05032 [list] [network] Morphine addiction (92 genes) |
|
| rno05034 [list] [network] Alcoholism (177 genes) |
|
| rno05163 [list] [network] Human cytomegalovirus infection (248 genes) |
|
| rno05166 [list] [network] Human T-cell leukemia virus 1 infection (249 genes) |
|
| rno05200 [list] [network] Pathways in cancer (538 genes) |
|
| rno05207 [list] [network] Chemical carcinogenesis - receptor activation (228 genes) |
|
| rno05414 [list] [network] Dilated cardiomyopathy (94 genes) |
|
| Protein |
NP_072122.2
XP_017453557.1
XP_038944541.1
|
| BLAST |
NP_072122.2
XP_017453557.1
XP_038944541.1
|
| Orthologous |
[Ortholog page]
ADCY5 (hsa)
ADCY6 (hsa)
Adcy6 (mmu)
Adcy6 (rno)
CG43373 (dme)
acy-4 (cel)
Adcy5 (mmu)
ADCY6 (gga)
ADCY5 (cfa)
ADCY6 (cfa)
adcy6b (dre)
adcy5 (dre)
adcy6a (dre)
ADCY6 (mcc)
ADCY5 (mcc)
ADCY6 (fca)
ADCY5 (fca)
LOC107050028 (gga)
|
Subcellular
localization
wolf |
|
plas 10
|
(predict for NP_072122.2)
|
|
plas 9
|
(predict for XP_017453557.1)
|
|
plas 9
|
(predict for XP_038944541.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| rno04022 |
cGMP-PKG signaling pathway |
6 |
 |
| rno04270 |
Vascular smooth muscle contraction |
6 |
 |
| rno00230 |
Purine metabolism |
5 |
 |
| rno04713 |
Circadian entrainment |
5 |
 |
| rno04924 |
Renin secretion |
5 |
 |
Genes directly connected with Adcy5 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 5.5 |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
[detail] |
24239 |
| 5.2 |
Adora2a |
adenosine A2a receptor |
[detail] |
25369 |
| 4.9 |
Gucy1a1 |
guanylate cyclase 1 soluble subunit alpha 1 |
[detail] |
497757 |
| 4.8 |
Rasl10b |
RAS-like, family 10, member B |
[detail] |
303382 |
| 4.7 |
Rhbdl3 |
rhomboid like 3 |
[detail] |
287556 |
| 4.2 |
Pde3a |
phosphodiesterase 3A |
[detail] |
50678 |
|
Coexpressed
gene list |
[Coexpressed gene list for Adcy5]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Adcy5 Gene
