[←][→] mmu  Mapk7 Gene
functional annotation
Function   mitogen-activated protein kinase 7  
GO BP
GO:0070377 [list] [network] negative regulation of ERK5 cascade  (1 genes)  IDA  
GO:0070375 [list] [network] ERK5 cascade  (3 genes)  ISO  
GO:0071499 [list] [network] cellular response to laminar fluid shear stress  (6 genes)  ISO  
GO:0034115 [list] [network] negative regulation of heterotypic cell-cell adhesion  (11 genes)  ISO  
GO:0070885 [list] [network] negative regulation of calcineurin-NFAT signaling cascade  (16 genes)  IMP  
GO:1902176 [list] [network] negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway  (18 genes)  ISO  
GO:0036003 [list] [network] positive regulation of transcription from RNA polymerase II promoter in response to stress  (27 genes)  ISO  
GO:2000352 [list] [network] negative regulation of endothelial cell apoptotic process  (31 genes)  ISO  
GO:2001240 [list] [network] negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (33 genes)  ISO  
GO:0043407 [list] [network] negative regulation of MAP kinase activity  (59 genes)  IDA  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (59 genes)  ISO  
GO:0060761 [list] [network] negative regulation of response to cytokine stimulus  (66 genes)  ISO  
GO:0071560 [list] [network] cellular response to transforming growth factor beta stimulus  (128 genes)  ISO  
GO:0000165 [list] [network] MAPK cascade  (136 genes)  ISO  
GO:0018105 [list] [network] peptidyl-serine phosphorylation  (187 genes)  IDA  
GO:0046777 [list] [network] protein autophosphorylation  (194 genes)  ISO  
GO:0045765 [list] [network] regulation of angiogenesis  (301 genes)  IMP  
GO:0071363 [list] [network] cellular response to growth factor stimulus  (426 genes)  ISO  
GO:0006468 [list] [network] protein phosphorylation  (665 genes)  IDA ISO  
GO:0016310 [list] [network] phosphorylation  (836 genes)  IEA  
GO:0043066 [list] [network] negative regulation of apoptotic process  (968 genes)  IDA  
GO:0007049 [list] [network] cell cycle  (1198 genes)  IEA  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (1250 genes)  ISO  
GO:0035556 [list] [network] intracellular signal transduction  (1356 genes)  IBA  
GO:0051247 [list] [network] positive regulation of protein metabolic process  (1454 genes)  ISO  
GO:0030154 [list] [network] cell differentiation  (3713 genes)  IEA  
GO CC
GO:0016605 [list] [network] PML body  (76 genes)  ISO  
GO:0005654 [list] [network] nucleoplasm  (3580 genes)  ISO  
GO:0005829 [list] [network] cytosol  (3785 genes)  IDA ISO  
GO:0005634 [list] [network] nucleus  (7226 genes)  IBA IDA ISO  
GO:0005737 [list] [network] cytoplasm  (11434 genes)  IBA IDA ISO  
GO MF
GO:0004707 [list] [network] MAP kinase activity  (15 genes)  IBA ISO  
GO:0051019 [list] [network] mitogen-activated protein kinase binding  (40 genes)  ISO  
GO:0004674 [list] [network] protein serine/threonine kinase activity  (442 genes)  IBA IDA  
GO:0004672 [list] [network] protein kinase activity  (583 genes)  IDA  
GO:0016301 [list] [network] kinase activity  (740 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (1396 genes)  ISO  
GO:0000166 [list] [network] nucleotide binding  (2052 genes)  IEA  
GO:0016740 [list] [network] transferase activity  (2235 genes)  IEA  
GO:0005515 [list] [network] protein binding  (9507 genes)  IPI  
KEGG mmu04010 [list] [network] MAPK signaling pathway (294 genes)
mmu04540 [list] [network] Gap junction (86 genes)
mmu04657 [list] [network] IL-17 signaling pathway (91 genes)
mmu04722 [list] [network] Neurotrophin signaling pathway (121 genes)
mmu04912 [list] [network] GnRH signaling pathway (90 genes)
mmu04921 [list] [network] Oxytocin signaling pathway (153 genes)
mmu05206 [list] [network] MicroRNAs in cancer (303 genes)
mmu05418 [list] [network] Fluid shear stress and atherosclerosis (148 genes)
Protein NP_001277962.1  NP_001277963.1  NP_001277964.1  NP_001277965.1  NP_001277966.1  NP_001348918.1  NP_035971.1  XP_006533340.1  XP_006533343.1  XP_006533347.1  XP_006533348.1  XP_006533349.1  XP_030101845.1  XP_030101846.1  XP_030101847.1  XP_030101848.1  XP_030101849.1  XP_030101850.1  XP_030101851.1  XP_030101853.1  XP_036012575.1  XP_036012576.1  XP_036012577.1  XP_036012578.1  XP_036012579.1 
BLAST NP_001277962.1  NP_001277963.1  NP_001277964.1  NP_001277965.1  NP_001277966.1  NP_001348918.1  NP_035971.1  XP_006533340.1  XP_006533343.1  XP_006533347.1  XP_006533348.1  XP_006533349.1  XP_030101845.1  XP_030101846.1  XP_030101847.1  XP_030101848.1  XP_030101849.1  XP_030101850.1  XP_030101851.1  XP_030101853.1  XP_036012575.1  XP_036012576.1  XP_036012577.1  XP_036012578.1  XP_036012579.1 
Orthologous [Ortholog page] MAPK1 (hsa)  MAPK3 (hsa)  MAPK7 (hsa)  Mapk1 (mmu)  Mapk3 (mmu)  Erk7 (dme)  Mapk3 (rno)  Mapk7 (rno)  Mapk1 (rno)  mpk-2 (cel)  mpk-1 (cel)  mapk-15 (cel)  pmk-3 (cel)  sma-5 (cel)  MAPK15 (hsa)  Mapk15 (rno)  Mapk15 (mmu)  F09C12.2 (cel)  mapk1 (dre)  MAPK3 (gga)  mapk3 (dre)  MAPK15 (gga)  MAPK1 (cfa)  MAPK15 (cfa)  MAPK7 (cfa)  mapk7 (dre)  mapk15 (dre)  MAPK1 (mcc)  MAPK7 (mcc)  MAPK3 (mcc)  FUS3 (sce)  KSS1 (sce)  KDX1 (sce)  SMK1 (sce)  SLT2 (sce)  p38c (dme)  rl (dme)  MAPK15 (mcc)  MAPK3 (cfa)  MAPK1 (fca)  MAPK3 (fca)  MAPK15 (fca)  MAPK7 (fca) 
Subcellular
localization
wolf
nucl 7,  cyto_nucl 5,  cyto 3  (predict for NP_001277962.1)
nucl 8,  cyto_nucl 6,  cyto 2  (predict for NP_001277963.1)
nucl 8,  cyto_nucl 5  (predict for NP_001277964.1)
nucl 8,  cyto_nucl 5  (predict for NP_001277965.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for NP_001277966.1)
nucl 8,  cyto_nucl 5  (predict for NP_001348918.1)
nucl 8,  cyto_nucl 6,  cyto 2  (predict for NP_035971.1)
nucl 8,  cyto_nucl 6,  cyto 2  (predict for XP_006533340.1)
nucl 8,  cyto_nucl 5  (predict for XP_006533343.1)
nucl 8,  cyto_nucl 5  (predict for XP_006533347.1)
nucl 8,  cyto_nucl 5  (predict for XP_006533348.1)
nucl 8,  cyto_nucl 5  (predict for XP_006533349.1)
nucl 7,  cyto_nucl 5,  cyto 3  (predict for XP_030101845.1)
nucl 7,  cyto_nucl 5,  cyto 3  (predict for XP_030101846.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_030101847.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_030101848.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_030101849.1)
nucl 8,  cyto_nucl 5  (predict for XP_030101850.1)
nucl 8,  cyto_nucl 5  (predict for XP_030101851.1)
nucl 8,  cyto_nucl 5  (predict for XP_030101853.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_036012575.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_036012576.1)
nucl 8,  cyto_nucl 5  (predict for XP_036012577.1)
nucl 8,  cyto_nucl 5  (predict for XP_036012578.1)
nucl 8,  cyto_nucl 5  (predict for XP_036012579.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04390 Hippo signaling pathway 2
mmu04530 Tight junction 2
mmu05165 Human papillomavirus infection 2
mmu05206 MicroRNAs in cancer 2
Genes directly connected with Mapk7 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
7.2 Map1s microtubule-associated protein 1S [detail] 0 270058
6.0 Llgl1 LLGL1 scribble cell polarity complex component [detail] 0 16897
5.3 Taf1c TATA-box binding protein associated factor, RNA polymerase I, C [detail] 0 21341
5.3 Plscr3 phospholipid scramblase 3 [detail] 0 70310
Coexpressed
gene list		 [Coexpressed gene list for Mapk7]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 23939      
Refseq ID (protein) NP_001277962.1 
NP_001277963.1 
NP_001277964.1 
NP_001277965.1 
NP_001277966.1 
NP_001348918.1 
NP_035971.1 
XP_006533340.1 
XP_006533343.1 
XP_006533347.1 
XP_006533348.1 
XP_006533349.1 
XP_030101845.1 
XP_030101846.1 
XP_030101847.1 
XP_030101848.1 
XP_030101849.1 
XP_030101850.1 
XP_030101851.1 
XP_030101853.1 
XP_036012575.1 
XP_036012576.1 
XP_036012577.1 
XP_036012578.1 
XP_036012579.1 


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