| functional annotation |
| Function |
mitogen-activated protein kinase 7 |
|
| GO BP |
|
GO:0070377 [list] [network] negative regulation of ERK5 cascade
|
(1 genes)
|
ISO
|
 |
|
GO:0070375 [list] [network] ERK5 cascade
|
(3 genes)
|
IMP
|
|
|
GO:0071499 [list] [network] cellular response to laminar fluid shear stress
|
(6 genes)
|
ISO
|
|
|
GO:0034115 [list] [network] negative regulation of heterotypic cell-cell adhesion
|
(11 genes)
|
ISO
|
|
|
GO:0070885 [list] [network] negative regulation of calcineurin-NFAT signaling cascade
|
(15 genes)
|
ISO
|
|
|
GO:1902176 [list] [network] negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
|
(19 genes)
|
ISO
|
|
|
GO:0036003 [list] [network] positive regulation of transcription from RNA polymerase II promoter in response to stress
|
(27 genes)
|
ISO
|
|
|
GO:2000352 [list] [network] negative regulation of endothelial cell apoptotic process
|
(33 genes)
|
ISO
|
|
|
GO:2001240 [list] [network] negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
(36 genes)
|
ISO
|
|
|
GO:0043407 [list] [network] negative regulation of MAP kinase activity
|
(61 genes)
|
ISO
|
|
|
GO:0060761 [list] [network] negative regulation of response to cytokine stimulus
|
(64 genes)
|
ISO
|
|
|
GO:0070301 [list] [network] cellular response to hydrogen peroxide
|
(102 genes)
|
ISO
|
|
|
GO:0000165 [list] [network] MAPK cascade
|
(151 genes)
|
IEA
IMP
|
|
|
GO:0071560 [list] [network] cellular response to transforming growth factor beta stimulus
|
(167 genes)
|
ISO
|
|
|
GO:0018105 [list] [network] peptidyl-serine phosphorylation
|
(188 genes)
|
ISO
|
|
|
GO:0046777 [list] [network] protein autophosphorylation
|
(198 genes)
|
IDA
|
|
|
GO:0045765 [list] [network] regulation of angiogenesis
|
(302 genes)
|
ISO
|
|
|
GO:0071363 [list] [network] cellular response to growth factor stimulus
|
(567 genes)
|
ISO
|
|
|
GO:0006468 [list] [network] protein phosphorylation
|
(680 genes)
|
IDA
IEA
ISO
|
|
|
GO:0043066 [list] [network] negative regulation of apoptotic process
|
(978 genes)
|
ISO
|
|
|
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II
|
(1255 genes)
|
ISO
|
|
|
GO:0035556 [list] [network] intracellular signal transduction
|
(1357 genes)
|
IBA
|
|
|
GO:0051247 [list] [network] positive regulation of protein metabolic process
|
(1490 genes)
|
ISO
|
|
|
GO:0030154 [list] [network] cell differentiation
|
(3536 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004707 [list] [network] MAP kinase activity
|
(15 genes)
|
IBA
IDA
IEA
|
|
|
GO:0051019 [list] [network] mitogen-activated protein kinase binding
|
(42 genes)
|
ISO
|
|
|
GO:0106310 [list] [network] protein serine kinase activity
|
(239 genes)
|
IEA
|
|
|
GO:0106311 [list] [network] protein threonine kinase activity
|
(239 genes)
|
IEA
|
|
|
GO:0004674 [list] [network] protein serine/threonine kinase activity
|
(395 genes)
|
IBA
ISO
|
|
|
GO:0004672 [list] [network] protein kinase activity
|
(557 genes)
|
IEA
ISO
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1380 genes)
|
IDA
IEA
|
|
|
GO:0005515 [list] [network] protein binding
|
(7349 genes)
|
IPI
|
|
|
| KEGG |
rno04010 [list] [network] MAPK signaling pathway (293 genes) |
 |
| rno04540 [list] [network] Gap junction (87 genes) |
|
| rno04657 [list] [network] IL-17 signaling pathway (91 genes) |
|
| rno04722 [list] [network] Neurotrophin signaling pathway (120 genes) |
|
| rno04912 [list] [network] GnRH signaling pathway (90 genes) |
|
| rno04921 [list] [network] Oxytocin signaling pathway (155 genes) |
|
| rno05206 [list] [network] MicroRNAs in cancer (292 genes) |
|
| rno05418 [list] [network] Fluid shear stress and atherosclerosis (151 genes) |
|
| Protein |
NP_001178476.1
XP_006246479.1
XP_006246480.1
XP_006246482.1
XP_008765978.1
XP_038940963.1
XP_038940964.1
|
| BLAST |
NP_001178476.1
XP_006246479.1
XP_006246480.1
XP_006246482.1
XP_008765978.1
XP_038940963.1
XP_038940964.1
|
| Orthologous |
[Ortholog page]
MAPK1 (hsa)
MAPK3 (hsa)
MAPK7 (hsa)
Mapk7 (mmu)
Mapk1 (mmu)
Mapk3 (mmu)
Erk7 (dme)
Mapk3 (rno)
Mapk1 (rno)
mpk-2 (cel)
mpk-1 (cel)
mapk-15 (cel)
pmk-3 (cel)
sma-5 (cel)
MAPK15 (hsa)
Mapk15 (rno)
Mapk15 (mmu)
F09C12.2 (cel)
mapk1 (dre)
MAPK3 (gga)
mapk3 (dre)
MAPK15 (gga)
MAPK1 (cfa)
MAPK15 (cfa)
MAPK7 (cfa)
mapk7 (dre)
mapk15 (dre)
MAPK1 (mcc)
MAPK7 (mcc)
MAPK3 (mcc)
FUS3 (sce)
KSS1 (sce)
KDX1 (sce)
SMK1 (sce)
SLT2 (sce)
p38c (dme)
rl (dme)
MAPK15 (mcc)
MAPK3 (cfa)
MAPK1 (fca)
MAPK3 (fca)
MAPK15 (fca)
MAPK7 (fca)
|
Subcellular
localization
wolf |
|
nucl 8,
cyto_nucl 6,
cyto 2
|
(predict for NP_001178476.1)
|
|
nucl 8,
cyto_nucl 6,
cyto 2
|
(predict for XP_006246479.1)
|
|
nucl 8,
cyto_nucl 6,
cyto 2
|
(predict for XP_006246480.1)
|
|
nucl 8,
cyto_nucl 5
|
(predict for XP_006246482.1)
|
|
nucl 8,
cyto_nucl 5
|
(predict for XP_008765978.1)
|
|
nucl 8,
cyto_nucl 6,
cyto 2
|
(predict for XP_038940963.1)
|
|
nucl 8,
cyto_nucl 5
|
(predict for XP_038940964.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| rno03040 |
Spliceosome |
3 |
 |
| rno04010 |
MAPK signaling pathway |
2 |
 |
| rno04024 |
cAMP signaling pathway |
2 |
 |
| rno04066 |
HIF-1 signaling pathway |
2 |
 |
| rno04657 |
IL-17 signaling pathway |
2 |
 |
Genes directly connected with Mapk7 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 5.7 |
Wiz |
WIZ zinc finger |
[detail] |
314598 |
| 5.7 |
Dtx2 |
deltex E3 ubiquitin ligase 2 |
[detail] |
304591 |
| 5.3 |
Usp42 |
ubiquitin specific peptidase 42 |
[detail] |
288482 |
|
Coexpressed
gene list |
[Coexpressed gene list for Mapk7]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Mapk7 Gene
