KEGG 04520 Adherens junction
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04520 Adherens junction 25
hsa04810 Regulation of actin cytoskeleton 14
hsa05132 Salmonella infection 14
hsa04530 Tight junction 13
hsa05130 Pathogenic Escherichia coli infection 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04520 Adherens junction 33
mmu04810 Regulation of actin cytoskeleton 19
mmu04530 Tight junction 16
mmu05132 Salmonella infection 15
mmu04015 Rap1 signaling pathway 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04520 Adherens junction 29
rno05200 Pathways in cancer 12
rno04530 Tight junction 12
rno04810 Regulation of actin cytoskeleton 12
rno04670 Leukocyte transendothelial migration 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04520 Adherens junction 37
gga04510 Focal adhesion 15
gga04810 Regulation of actin cytoskeleton 13
gga04530 Tight junction 11
gga04310 Wnt signaling pathway 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04520 Adherens junction 57
dre04810 Regulation of actin cytoskeleton 23
dre04530 Tight junction 21
dre04310 Wnt signaling pathway 20
dre04510 Focal adhesion 19
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04520 Adherens junction 38
mcc04510 Focal adhesion 15
mcc05200 Pathways in cancer 15
mcc05205 Proteoglycans in cancer 14
mcc04015 Rap1 signaling pathway 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04520 Adherens junction 29
cfa05200 Pathways in cancer 13
cfa04510 Focal adhesion 11
cfa04015 Rap1 signaling pathway 10
cfa04810 Regulation of actin cytoskeleton 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04520 Adherens junction 29
fca05200 Pathways in cancer 13
fca04015 Rap1 signaling pathway 12
fca04510 Focal adhesion 10
fca05205 Proteoglycans in cancer 10
Gene list in the network
Symbol Function*
ACTB actin beta
ACTG1 actin gamma 1
ACTN4 actinin alpha 4
ACTN1 actinin alpha 1
RHOA ras homolog family member A
CAMK4 calcium/calmodulin dependent protein kinase IV
CDC42 cell division cycle 42
CREBBP CREB binding protein
EP300 E1A binding protein p300
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A
GNAI2 G protein subunit alpha i2
IGF1R insulin like growth factor 1 receptor
SMAD3 SMAD family member 3
AFDN afadin, adherens junction formation factor
MYH9 myosin heavy chain 9
MYO6 myosin VI
PTPN6 protein tyrosine phosphatase non-receptor type 6
RAC1 Rac family small GTPase 1
RSU1 Ras suppressor protein 1
TCF7 transcription factor 7
TCF7L2 transcription factor 7 like 2
TJP1 tight junction protein 1
TLN1 talin 1
TPM4 tropomyosin 4
VCL vinculin
WAS WASP actin nucleation promoting factor
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZYX zyxin
ARID1A AT-rich interaction domain 1A
IQGAP1 IQ motif containing GTPase activating protein 1
WDR1 WD repeat domain 1
ARPC4 actin related protein 2/3 complex subunit 4
WASF2 WASP family member 2
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
NCKAP1 NCK associated protein 1
EDAR ectodysplasin A receptor
RBPMS RNA binding protein, mRNA processing factor
DNMBP dynamin binding protein
MED13L mediator complex subunit 13L
BRD4 bromodomain containing 4
LEF1 lymphoid enhancer binding factor 1
PARD3 par-3 family cell polarity regulator
DENND1C DENN domain containing 1C
TCF7L1 transcription factor 7 like 1
TUBB tubulin beta class I
Symbol Function*
Actb actin, beta
Actg1 actin, gamma, cytoplasmic 1
Rhoa ras homolog family member A
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta
Axin2 axin 2
Ctnna1 catenin (cadherin associated protein), alpha 1
Ctnnd1 catenin (cadherin associated protein), delta 1
Cdc42 cell division cycle 42
Cfl1 cofilin 1, non-muscle
Crebbp CREB binding protein
Hcls1 hematopoietic cell specific Lyn substrate 1
Ptpn6 protein tyrosine phosphatase, non-receptor type 6
Insr insulin receptor
Lasp1 LIM and SH3 protein 1
Lef1 lymphoid enhancer binding factor 1
Met met proto-oncogene
Afdn afadin, adherens junction formation factor
Myh9 myosin, heavy polypeptide 9, non-muscle
Myo6 myosin VI
Pfn1 profilin 1
Ptprb protein tyrosine phosphatase, receptor type, B
Ptprk protein tyrosine phosphatase, receptor type, K
Ptprm protein tyrosine phosphatase, receptor type, M
Rac1 Rac family small GTPase 1
Rac2 Rac family small GTPase 2
Src Rous sarcoma oncogene
Tcf7 transcription factor 7, T cell specific
Tcf7l1 transcription factor 7 like 1 (T cell specific, HMG box)
Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box
Tjp1 tight junction protein 1
Tjp2 tight junction protein 2
Vav1 vav 1 oncogene
Vcl vinculin
Was Wiskott-Aldrich syndrome
Yes1 YES proto-oncogene 1, Src family tyrosine kinase
Iqgap1 IQ motif containing GTPase activating protein 1
Nckap1 NCK-associated protein 1
Brd4 bromodomain containing 4
Nectin3 nectin cell adhesion molecule 3
Actn4 actinin alpha 4
Dlg5 discs large MAGUK scaffold protein 5
Wasl WASP like actin nucleation promoting factor
Actr3 ARP3 actin-related protein 3
Sash3 SAM and SH3 domain containing 3
Pard3 par-3 family cell polarity regulator
Actn1 actinin, alpha 1
Flna filamin, alpha
Etl4 enhancer trap locus 4
Tnrc6b trinucleotide repeat containing 6b
Adgrf5 adhesion G protein-coupled receptor F5
Arhgap30 Rho GTPase activating protein 30
Wasf2 WASP family, member 2
Kat6a K(lysine) acetyltransferase 6A
Ptpn7 protein tyrosine phosphatase, non-receptor type 7
Ep300 E1A binding protein p300
Lmo7 LIM domain only 7
Symbol Function*
Smad3 SMAD family member 3
Myh9 myosin, heavy chain 9
Afdn afadin, adherens junction formation factor
Ptprm protein tyrosine phosphatase, receptor type, M
Ptprj protein tyrosine phosphatase, receptor type, J
Smad4 SMAD family member 4
Cr1l complement C3b/C4b receptor 1 like
Crebbp CREB binding protein
Actn4 actinin alpha 4
Cdc42 cell division cycle 42
Rab2a RAB2A, member RAS oncogene family
Actn1 actinin, alpha 1
Actb actin, beta
Pard3 par-3 family cell polarity regulator
Laptm5 lysosomal protein transmembrane 5
Cdc42bpb CDC42 binding protein kinase beta
Tjp2 tight junction protein 2
Ptpn6 protein tyrosine phosphatase, non-receptor type 6
Rhoa ras homolog family member A
Tpm3 tropomyosin 3
Lef1 lymphoid enhancer binding factor 1
Zbtb20 zinc finger and BTB domain containing 20
Atxn2 ataxin 2
Tjp1 tight junction protein 1
Flna filamin A
Nek9 NIMA-related kinase 9
Vcl vinculin
Ctnna1 catenin alpha 1
Zfhx3 zinc finger homeobox 3
Gatad2b GATA zinc finger domain containing 2B
Ctnnd1 catenin delta 1
Wasf2 WASP family member 2
Ptprb protein tyrosine phosphatase, receptor type, B
Dmxl2 Dmx-like 2
Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Was WASP actin nucleation promoting factor
Sash3 SAM and SH3 domain containing 3
Iqgap1 IQ motif containing GTPase activating protein 1
Tcf7 transcription factor 7
Rac1 Rac family small GTPase 1
Rac2 Rac family small GTPase 2
Nlk nemo like kinase
Arhgap30 Rho GTPase activating protein 30
Tcf7l2 transcription factor 7 like 2
Rsu1 Ras suppressor protein 1
Wasl WASP like actin nucleation promoting factor
Sorbs1 sorbin and SH3 domain containing 1
Symbol Function*
ACTN1 actinin, alpha 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7 like 1
RHOA ras homolog family member A
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
LEF1 lymphoid enhancer binding factor 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
IGF1R insulin like growth factor 1 receptor
CTNNB1 catenin beta 1
ACTN4 actinin, alpha 4
MET MET proto-oncogene, receptor tyrosine kinase
YES1 YES proto-oncogene 1, Src family tyrosine kinase
VCL vinculin
SRC SRC proto-oncogene, non-receptor tyrosine kinase
MYH9 myosin, heavy chain 9, non-muscle
EGFR epidermal growth factor receptor
ACTB actin, beta
DSTN destrin, actin depolymerizing factor
TJP1 tight junction protein 1
IQGAP3 IQ motif containing GTPase activating protein 3
FER fer (fps/fes related) tyrosine kinase
CTNNA1 catenin alpha 1
CASKIN1 CASK interacting protein 1
FAM234A family with sequence similarity 234 member A
CREBBP CREB binding protein
CORO1C coronin 1C
MSRB3 methionine sulfoxide reductase B3
EP300 E1A binding protein p300
TNRC6B trinucleotide repeat containing adaptor 6B
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
ZYX zyxin
NECTIN3 nectin cell adhesion molecule 3
SPEN spen family transcriptional repressor
LAPTM5 lysosomal protein transmembrane 5
INSR insulin receptor
PTPRM protein tyrosine phosphatase, receptor type M
AFDN afadin, adherens junction formation factor
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
WASF3L wiskott-Aldrich syndrome protein family member 3-like
SORBS1 sorbin and SH3 domain containing 1
TGFBR2L transforming growth factor beta receptor 2 like
PTPRF protein tyrosine phosphatase, receptor type F
RPRD2 regulation of nuclear pre-mRNA domain containing 2
ERBB2 erb-b2 receptor tyrosine kinase 2
WASF2 WAS protein family member 2
RAI14 retinoic acid induced 14
GOLM1 golgi membrane protein 1
PLEKHF1 pleckstrin homology and FYVE domain containing 1
PTPN6 protein tyrosine phosphatase non-receptor type 6
TGIF2 TGFB induced factor homeobox 2
CTNND1 catenin delta 1
JUP junction plakoglobin
ARHGDIA Rho GDP dissociation inhibitor alpha
LOC776816 actin, cytoplasmic 2-like
NECTIN1 nectin cell adhesion molecule 1
BRD4 bromodomain containing 4
MYO10 myosin X
TAGLN2 transgelin 2
Symbol Function*
elf1 E74-like ETS transcription factor 1
csnk2b casein kinase 2, beta polypeptide
csnk2a1 casein kinase 2, alpha 1 polypeptide
tcf7l1a transcription factor 7 like 1a
tcf7l1b transcription factor 7 like 1b
lef1 lymphoid enhancer-binding factor 1
fgfr1a fibroblast growth factor receptor 1a
ctnna1 catenin (cadherin-associated protein), alpha 1
actb1 actin, beta 1
actb2 actin, beta 2
smad3a SMAD family member 3a
cdh1 cadherin 1, type 1, E-cadherin (epithelial)
ptprfa protein tyrosine phosphatase receptor type Fa
insrb insulin receptor b
igf1ra insulin-like growth factor 1a receptor
igf1rb insulin-like growth factor 1b receptor
kat6a K(lysine) acetyltransferase 6A
neo1a neogenin 1a
coro1ca coronin, actin binding protein, 1Ca
actn4 actinin, alpha 4
si:ch1073-335m2.2 si:ch1073-335m2.2
ctnnb2 catenin, beta 2
smad3b SMAD family member 3b
arpc2 actin related protein 2/3 complex, subunit 2
rac1a Rac family small GTPase 1a
wasb WASP actin nucleation promoting factor b
ptpn6 protein tyrosine phosphatase non-receptor type 6
lcp2a lymphocyte cytosolic protein 2a
cotl1 coactosin-like F-actin binding protein 1
cyfip1 cytoplasmic FMR1 interacting protein 1
zgc:153867 zgc:153867
erbb2 erb-b2 receptor tyrosine kinase 2
wasf2 WASP family member 2
arf2a ADP-ribosylation factor 2a
pard3ab par-3 family cell polarity regulator alpha, b
rhoaa ras homolog gene family, member Aa
rhoac ras homolog gene family, member Ac
yes1 YES proto-oncogene 1, Src family tyrosine kinase
rac2 Rac family small GTPase 2
stxbp6 syntaxin binding protein 6 (amisyn)
zgc:86598 zgc:86598
snai2 snail family zinc finger 2
tln1 talin 1
ext1b exostosin glycosyltransferase 1b
tcf7 transcription factor 7
lifra LIF receptor subunit alpha a
vcla vinculin a
lims1 LIM and senescent cell antigen-like domains 1
serpinh1a serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
setd1a SET domain containing 1A, histone lysine methyltransferase
ctnnd1 catenin (cadherin-associated protein), delta 1
nectin1b nectin cell adhesion molecule 1b
trioa trio Rho guanine nucleotide exchange factor a
afdna afadin, adherens junction formation factor a
ptprc protein tyrosine phosphatase receptor type C
ep300a E1A binding protein p300 a
smad10a SMAD family member 10a
actn1 actinin, alpha 1
tgfbr1a transforming growth factor, beta receptor 1 a
pvrl2l PVR cell adhesion molecule related 2 like
myh9b myosin, heavy chain 9b, non-muscle
flna filamin A, alpha (actin binding protein 280)
rac1b Rac family small GTPase 1b
ubap2a ubiquitin associated protein 2a
fer fer (fps/fes related) tyrosine kinase
tjp1b tight junction protein 1b
ep300b E1A binding protein p300 b
man1a1 mannosidase, alpha, class 1A, member 1
crebbpa CREB binding protein a
crebbpb CREB binding protein b
pkn2b protein kinase N2b
maml1 mastermind-like transcriptional coactivator 1
farp2 FERM, RhoGEF and pleckstrin domain protein 2
fgfr1b fibroblast growth factor receptor 1b
wwtr1 WW domain containing transcription regulator 1
wasa WASP actin nucleation promoting factor a
LOC571757 DNA-binding protein SATB1-like
dock1 dedicator of cytokinesis 1
baiap2a BAR/IMD domain containing adaptor protein 2a
dgkaa diacylglycerol kinase, alpha a
zgc:158689 zgc:158689
snai1b snail family zinc finger 1b
cdc42l cell division cycle 42, like
tmsb4x thymosin beta 4 X-linked
ptprfb protein tyrosine phosphatase receptor type Fb
iqgap1 IQ motif containing GTPase activating protein 1
arhgap17b Rho GTPase activating protein 17b
cdk12 cyclin-dependent kinase 12
LOC100151049 Mtp family protein
mertka c-mer proto-oncogene tyrosine kinase a
LOC100331639 myosin-9-like
grb14 growth factor receptor-bound protein 14
map3k1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
vclb vinculin b
pard3aa par-3 family cell polarity regulator alpha, a
Symbol Function*
FYN FYN proto-oncogene, Src family tyrosine kinase
ACTB actin beta
CTNNA1 catenin alpha 1
NLK nemo like kinase
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
TCF7L1 transcription factor 7 like 1
LEF1 lymphoid enhancer binding factor 1
RAC2 Rac family small GTPase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
LMO7 LIM domain 7
MAPK1 mitogen-activated protein kinase 1
FLNA filamin A
PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta
SOX13 SRY-box transcription factor 13
PTPRF protein tyrosine phosphatase receptor type F
TCF7L2 transcription factor 7 like 2
LCP1 lymphocyte cytosolic protein 1
CTNND1 catenin delta 1
CREBBP CREB binding protein
MET MET proto-oncogene, receptor tyrosine kinase
BTBD11 BTB domain containing 11
CTTNBP2NL CTTNBP2 N-terminal like
LOC705671 actin, cytoplasmic 2-like
INSR insulin receptor
EP300 E1A binding protein p300
RHOA ras homolog family member A
PARD3 par-3 family cell polarity regulator
NECTIN3 nectin cell adhesion molecule 3
CDC42 cell division cycle 42
IGF1R insulin like growth factor 1 receptor
KIAA1522 KIAA1522
HNRNPK heterogeneous nuclear ribonucleoprotein K
IQGAP1 IQ motif containing GTPase activating protein 1
CA6 carbonic anhydrase 6
WASF3 WASP family member 3
TCF7 transcription factor 7
PTPRJ protein tyrosine phosphatase receptor type J
ATP10A ATPase phospholipid transporting 10A (putative)
ACTN1 actinin alpha 1
NECTIN2 nectin cell adhesion molecule 2
ACTG1 actin gamma 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
PTPN6 protein tyrosine phosphatase non-receptor type 6
WAS WASP actin nucleation promoting factor
CSNK2A1 casein kinase 2 alpha 1
KANSL1 KAT8 regulatory NSL complex subunit 1
TNRC18 trinucleotide repeat containing 18
SEPTIN2 septin 2
RAC1 Rac family small GTPase 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
PTPRB protein tyrosine phosphatase receptor type B
ARID1A AT-rich interaction domain 1A
TJP1 tight junction protein 1
VCL vinculin
PTPRM protein tyrosine phosphatase receptor type M
LSR lipolysis stimulated lipoprotein receptor
Symbol Function*
ACTB actin beta
TJP1 tight junction protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
AFDN afadin, adherens junction formation factor
IGF1R insulin like growth factor 1 receptor
CTNNA1 catenin alpha 1
BICRAL BRD4 interacting chromatin remodeling complex associated protein like
FYN FYN proto-oncogene, Src family tyrosine kinase
PTPRF protein tyrosine phosphatase receptor type F
ACTG1 actin gamma 1
PTPRK protein tyrosine phosphatase receptor type K
LMO7 LIM domain 7
TAF4 TATA-box binding protein associated factor 4
PARD3 par-3 family cell polarity regulator
LEF1 lymphoid enhancer binding factor 1
CYFIP1 cytoplasmic FMR1 interacting protein 1
VCL vinculin
POLR2A RNA polymerase II subunit A
BCAR1 BCAR1 scaffold protein, Cas family member
CREBBP CREB binding protein
PTPRM protein tyrosine phosphatase receptor type M
ACTN1 actinin alpha 1
JUP junction plakoglobin
FLNA filamin A
RAC2 Rac family small GTPase 2
TCF7 transcription factor 7
CTNND1 catenin delta 1
ACTN4 actinin alpha 4
INSR insulin receptor
SH3BP4 SH3 domain binding protein 4
FOXJ2 forkhead box J2
TCF7L2 transcription factor 7 like 2
SNAI2 snail family transcriptional repressor 2
WASF2 WASP family member 2
ARID1A AT-rich interaction domain 1A
MYO10 myosin X
FERMT2 FERM domain containing kindlin 2
PDGFA platelet derived growth factor subunit A
WAS WASP actin nucleation promoting factor
CSRP1 cysteine and glycine rich protein 1
GPSM3 G protein signaling modulator 3
NECTIN2 nectin cell adhesion molecule 2
TCF7L1 transcription factor 7 like 1
EP300 E1A binding protein p300
LUZP1 leucine zipper protein 1
SORBS1 sorbin and SH3 domain containing 1
SPEN spen family transcriptional repressor
FGFR1 fibroblast growth factor receptor 1
LOC119871191 uncharacterized LOC119871191
Symbol Function*
MET MET proto-oncogene, receptor tyrosine kinase
ITGB1 integrin subunit beta 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ACTG1 actin gamma 1
EGFR epidermal growth factor receptor
SNX7 sorting nexin 7
PTPRM protein tyrosine phosphatase receptor type M
PTPRF protein tyrosine phosphatase receptor type F
AFDN afadin, adherens junction formation factor
TJP1 tight junction protein 1
PTPN21 protein tyrosine phosphatase non-receptor type 21
KMT2E lysine methyltransferase 2E (inactive)
FGFR1 fibroblast growth factor receptor 1
KCTD10 potassium channel tetramerization domain containing 10
NECTIN2 nectin cell adhesion molecule 2
IRF6 interferon regulatory factor 6
MAPK1 mitogen-activated protein kinase 1
IQGAP1 IQ motif containing GTPase activating protein 1
DCP1A decapping mRNA 1A
EP300 E1A binding protein p300
S1PR2 sphingosine-1-phosphate receptor 2
VCL vinculin
TCF7L1 transcription factor 7 like 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ARID1B AT-rich interaction domain 1B
TGFBR2 transforming growth factor beta receptor 2
CTNND1 catenin delta 1
NECTIN4 nectin cell adhesion molecule 4
CREBBP CREB binding protein
NECTIN3 nectin cell adhesion molecule 3
CDH1 cadherin 1
TCF7L2 transcription factor 7 like 2
SEPTIN10 septin 10
KANK2 KN motif and ankyrin repeat domains 2
ACTN1 actinin alpha 1
MTMR1 myotubularin related protein 1
ACTB actin beta
GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PARD3 par-3 family cell polarity regulator
SNAI1 snail family transcriptional repressor 1
PTPRB protein tyrosine phosphatase receptor type B
GPATCH8 G-patch domain containing 8
RAC1 Rac family small GTPase 1
RBMS2 RNA binding motif single stranded interacting protein 2
LOC102902292 uncharacterized LOC102902292


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