KEGG 04916 Melanogenesis
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04916 Melanogenesis 33
hsa05200 Pathways in cancer 29
hsa04934 Cushing syndrome 24
hsa04310 Wnt signaling pathway 20
hsa05165 Human papillomavirus infection 19
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04916 Melanogenesis 41
mmu05200 Pathways in cancer 41
mmu04934 Cushing syndrome 31
mmu05022 Pathways of neurodegeneration - multiple diseases 30
mmu05010 Alzheimer disease 28
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04916 Melanogenesis 38
rno05200 Pathways in cancer 36
rno05022 Pathways of neurodegeneration - multiple diseases 26
rno04934 Cushing syndrome 26
rno05010 Alzheimer disease 23
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04916 Melanogenesis 41
gga04310 Wnt signaling pathway 27
gga04150 mTOR signaling pathway 20
gga04261 Adrenergic signaling in cardiomyocytes 14
gga04371 Apelin signaling pathway 12
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04916 Melanogenesis 53
dre04310 Wnt signaling pathway 33
dre04150 mTOR signaling pathway 24
dre04912 GnRH signaling pathway 20
dre04261 Adrenergic signaling in cardiomyocytes 19
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04916 Melanogenesis 22
mcc05200 Pathways in cancer 22
mcc04934 Cushing syndrome 17
mcc05165 Human papillomavirus infection 15
mcc04310 Wnt signaling pathway 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04916 Melanogenesis 35
cfa05200 Pathways in cancer 30
cfa04934 Cushing syndrome 22
cfa04310 Wnt signaling pathway 18
cfa05165 Human papillomavirus infection 17
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04916 Melanogenesis 29
fca05200 Pathways in cancer 26
fca04934 Cushing syndrome 19
fca05022 Pathways of neurodegeneration - multiple diseases 18
fca04921 Oxytocin signaling pathway 17
Gene list in the network
Symbol Function*
ADCY1 adenylate cyclase 1
ADCY7 adenylate cyclase 7
ADCY9 adenylate cyclase 9
CALML3 calmodulin like 3
CAMK4 calcium/calmodulin dependent protein kinase IV
CAMK2B calcium/calmodulin dependent protein kinase II beta
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
DCT dopachrome tautomerase
EP300 E1A binding protein p300
MLANA melan-A
GNAI3 G protein subunit alpha i3
GNAS GNAS complex locus
ARHGAP35 Rho GTPase activating protein 35
GSK3B glycogen synthase kinase 3 beta
NRAS NRAS proto-oncogene, GTPase
PLCB2 phospholipase C beta 2
PRKCA protein kinase C alpha
MAP2K2 mitogen-activated protein kinase kinase 2
TCF7 transcription factor 7
TCF7L2 transcription factor 7 like 2
TYR tyrosinase
TYRP1 tyrosinase related protein 1
USF2 upstream transcription factor 2, c-fos interacting
WNT3 Wnt family member 3
WNT5A Wnt family member 5A
WNT6 Wnt family member 6
WNT7B Wnt family member 7B
WNT11 Wnt family member 11
WNT9A Wnt family member 9A
ZNF148 zinc finger protein 148
FZD9 frizzled class receptor 9
NTN1 netrin 1
EDAR ectodysplasin A receptor
ZHX3 zinc fingers and homeoboxes 3
ZCCHC14 zinc finger CCHC-type containing 14
LEF1 lymphoid enhancer binding factor 1
CALML5 calmodulin like 5
WNT10A Wnt family member 10A
WNT5B Wnt family member 5B
TCF7L1 transcription factor 7 like 1
NOTUM notum, palmitoleoyl-protein carboxylesterase
ADCY4 adenylate cyclase 4
LOC105371058 uncharacterized LOC105371058
Symbol Function*
Adcy7 adenylate cyclase 7
Adcy8 adenylate cyclase 8
Adcy9 adenylate cyclase 9
Axin2 axin 2
Calm1 calmodulin 1
Calm2 calmodulin 2
Calm3 calmodulin 3
Cfl1 cofilin 1, non-muscle
Crebbp CREB binding protein
Dct dopachrome tautomerase
Fzd1 frizzled class receptor 1
Fzd3 frizzled class receptor 3
Fzd7 frizzled class receptor 7
Fzd8 frizzled class receptor 8
Fzd9 frizzled class receptor 9
Gas1 growth arrest specific 1
Gnai1 guanine nucleotide binding protein (G protein), alpha inhibiting 1
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2
Gnaq guanine nucleotide binding protein, alpha q polypeptide
Gnb2 guanine nucleotide binding protein (G protein), beta 2
Hras Harvey rat sarcoma virus oncogene
Ksr1 kinase suppressor of ras 1
Lef1 lymphoid enhancer binding factor 1
Mbd3 methyl-CpG binding domain protein 3
Msx2 msh homeobox 2
Prkca protein kinase C, alpha
Plcb2 phospholipase C, beta 2
Atxn1 ataxin 1
Pmel premelanosome protein
Tcf7 transcription factor 7, T cell specific
Tcf7l1 transcription factor 7 like 1 (T cell specific, HMG box)
Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box
Tyrp1 tyrosinase-related protein 1
Slc45a2 solute carrier family 45, member 2
Wnt10a wingless-type MMTV integration site family, member 10A
Wnt10b wingless-type MMTV integration site family, member 10B
Wnt4 wingless-type MMTV integration site family, member 4
Wnt5a wingless-type MMTV integration site family, member 5A
Wnt5b wingless-type MMTV integration site family, member 5B
Wnt6 wingless-type MMTV integration site family, member 6
Wnt7a wingless-type MMTV integration site family, member 7A
Wnt7b wingless-type MMTV integration site family, member 7B
Map2k2 mitogen-activated protein kinase kinase 2
Mapk3 mitogen-activated protein kinase 3
Ror2 receptor tyrosine kinase-like orphan receptor 2
Gsk3b glycogen synthase kinase 3 beta
Fzd2 frizzled class receptor 2
Nudt11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
Calml3 calmodulin-like 3
Mlana melan-A
Calm4 calmodulin 4
Fzd10 frizzled class receptor 10
Krt5 keratin 5
Fgfrl1 fibroblast growth factor receptor-like 1
Mlc1 megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Wnt9a wingless-type MMTV integration site family, member 9A
Gm94 predicted gene 94
Gatad2b GATA zinc finger domain containing 2B
Kat6a K(lysine) acetyltransferase 6A
Rasal3 RAS protein activator like 3
Ep300 E1A binding protein p300
Cracr2a calcium release activated channel regulator 2A
Symbol Function*
Calm1 calmodulin 1
Calm3 calmodulin 3
Camk2d calcium/calmodulin-dependent protein kinase II delta
Nras NRAS proto-oncogene, GTPase
Prkca protein kinase C, alpha
Plcb4 phospholipase C, beta 4
Mitf melanocyte inducing transcription factor
Adcy6 adenylate cyclase 6
Prkg2 protein kinase cGMP-dependent 2
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Gnai3 G protein subunit alpha i3
Nfic nuclear factor I/C
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Calm2 calmodulin 2
Ednrb endothelin receptor type B
Crebbp CREB binding protein
Map2k2 mitogen activated protein kinase kinase 2
Kitlg KIT ligand
Mtpn myotrophin
Gnaq G protein subunit alpha q
Gsk3b glycogen synthase kinase 3 beta
Slc4a4 solute carrier family 4 member 4
Wnt7a Wnt family member 7A
Mapk1 mitogen activated protein kinase 1
Septin2 septin 2
Wnt11 Wnt family member 11
Lef1 lymphoid enhancer binding factor 1
Map2k1 mitogen activated protein kinase kinase 1
Ep300 E1A binding protein p300
Camk2g calcium/calmodulin-dependent protein kinase II gamma
Foxc2 forkhead box C2
Fzd6 frizzled class receptor 6
Dct dopachrome tautomerase
Hras HRas proto-oncogene, GTPase
Slc35g1 solute carrier family 35, member G1
Tyrp1 tyrosinase-related protein 1
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Dvl3 dishevelled segment polarity protein 3
Fam193a family with sequence similarity 193, member A
Arid5b AT-rich interaction domain 5B
Fnbp1l formin binding protein 1-like
Tcf7l1 transcription factor 7 like 1
Mlf2 myeloid leukemia factor 2
Casz1 castor zinc finger 1
Wnt7b Wnt family member 7B
Wnt6 Wnt family member 6
Wnt10a Wnt family member 10A
Fzd5 frizzled class receptor 5
Tcf7 transcription factor 7
Fzd10 frizzled class receptor 10
Wnt16 Wnt family member 16
Setd1b SET domain containing 1B, histone lysine methyltransferase
Fzd7 frizzled class receptor 7
Kmt2d lysine methyltransferase 2D
Symbol Function*
FZD10 frizzled class receptor 10
EDNRB2 endothelin receptor B subtype 2
TYR tyrosinase
FZD8 frizzled class receptor 8
FZD2 frizzled class receptor 2
GNAI3 G protein subunit alpha i3
WNT7A Wnt family member 7A
CAMK2B calcium/calmodulin dependent protein kinase II beta
CDX2 caudal type homeobox 2
WNT2B Wnt family member 2B
TRIB2 tribbles pseudokinase 2
TCF7 transcription factor 7 (T-cell specific, HMG-box)
WNT6 Wnt family member 6
WNT3A Wnt family member 3A
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
WNT4 Wnt family member 4
FZD5 frizzled class receptor 5
WNT5A Wnt family member 5A
DCT dopachrome tautomerase
CALM2 calmodulin 2
LEF1 lymphoid enhancer binding factor 1
TYRP1 tyrosinase related protein 1
PMEL premelanosome protein
MAP2K2 mitogen-activated protein kinase kinase 2
GNAI2 G protein subunit alpha i2
GNAI1 G protein subunit alpha i1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
WNT8A Wnt family member 8A
MAP2K1 mitogen-activated protein kinase kinase 1
CREBBP CREB binding protein
CALML3 calmodulin like 3
PLCB4 phospholipase C beta 4
PRKCA protein kinase C alpha
EP300 E1A binding protein p300
WNT5B Wnt family member 5B
GSK3A glycogen synthase kinase 3 alpha
GPR143 G protein-coupled receptor 143
DVL1 dishevelled segment polarity protein 1
SPEN spen family transcriptional repressor
SF3A2 splicing factor 3a subunit 2
ADCY1 adenylate cyclase 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
CAMK2D calcium/calmodulin dependent protein kinase II delta
SLC38A11 solute carrier family 38 member 11
PRKACB protein kinase cAMP-activated catalytic subunit beta
SPHKAP SPHK1 interactor, AKAP domain containing
DVL2 dishevelled segment polarity protein 2
WNT7B Wnt family member 7B
OCA2 OCA2 melanosomal transmembrane protein
WNT10A Wnt family member 10A
MLANA melan-A
BRD4 bromodomain containing 4
LOC107050028 adenylate cyclase type 6-like
LOC107050029 serine/arginine repetitive matrix protein 1-like
CBX6 chromobox 6
LOC107056274 rho-related BTB domain-containing protein 2-like
LOC112529929 keratin, type II cytoskeletal 4-like
LOC121107625 uncharacterized LOC121107625
Symbol Function*
mitfa melanocyte inducing transcription factor a
wnt5b wingless-type MMTV integration site family, member 5b
wnt4 wingless-type MMTV integration site family, member 4
wnt2 wingless-type MMTV integration site family member 2
tyr tyrosinase
smo smoothened, frizzled class receptor
fzd4 frizzled class receptor 4
fzd10 frizzled class receptor 10
fzd7a frizzled class receptor 7a
nras NRAS proto-oncogene, GTPase
fzd7b frizzled class receptor 7b
irx3a iroquois homeobox 3a
tcf7l1a transcription factor 7 like 1a
tcf7l1b transcription factor 7 like 1b
fzd9b frizzled class receptor 9b
notch3 notch receptor 3
fzd8a frizzled class receptor 8a
dct dopachrome tautomerase
atp1b3b ATPase Na+/K+ transporting subunit beta 3b
calm2b calmodulin 2b, (phosphorylase kinase, delta)
kat6a K(lysine) acetyltransferase 6A
pmela premelanosome protein a
calm3b calmodulin 3b (phosphorylase kinase, delta)
si:ch1073-335m2.2 si:ch1073-335m2.2
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
dvl2 dishevelled segment polarity protein 2
mapkapk2a MAPK activated protein kinase 2a
calm3a calmodulin 3a (phosphorylase kinase, delta)
akap13 A-kinase anchoring protein 13
gnai2b guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
calm2a calmodulin 2a (phosphorylase kinase, delta)
calm1b calmodulin 1b
gnao1b guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
prkcbb protein kinase C, beta b
calm1a calmodulin 1a
map2k1 mitogen-activated protein kinase kinase 1
tyrp1b tyrosinase-related protein 1b
camk2d1 calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
prkcaa protein kinase C, alpha, a
erlin1 ER lipid raft associated 1
slc38a11 solute carrier family 38 member 11
setd1a SET domain containing 1A, histone lysine methyltransferase
gnas GNAS complex locus
fzd1 frizzled class receptor 1
gsk3bb glycogen synthase kinase 3 beta, genome duplicate b
slc45a2 solute carrier family 45 member 2
ryk receptor like tyrosine kinase
ep300a E1A binding protein p300 a
camk2b1 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
btbd11a BTB (POZ) domain containing 11a
prkacbb protein kinase, cAMP-dependent, catalytic, beta b
map2k2a mitogen-activated protein kinase kinase 2a
prkacaa protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
tmem131l transmembrane 131 like
ep300b E1A binding protein p300 b
wnt7aa wingless-type MMTV integration site family, member 7Aa
fzd3a frizzled class receptor 3a
crebbpa CREB binding protein a
crebbpb CREB binding protein b
maml1 mastermind-like transcriptional coactivator 1
LOC568110 protein Wnt-7a-like
wnt3 wingless-type MMTV integration site family, member 3
slco3a1a solute carrier organic anion transporter family member 3A1a
dvl1a dishevelled segment polarity protein 1a
slc24a5 solute carrier family 24 member 5
adcy3a adenylate cyclase 3a
creb3l2 cAMP responsive element binding protein 3-like 2
wnt16 wingless-type MMTV integration site family, member 16
camk2g1 calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
LOC799194 tetraspanin-10
fgfr4 fibroblast growth factor receptor 4
prkcba protein kinase C, beta a
si:ch1073-459b3.2 si:ch1073-459b3.2
tyrp1a tyrosinase-related protein 1a
adcy9 adenylate cyclase 9
ldlrad2 low density lipoprotein receptor class A domain containing 2
Symbol Function*
GNAO1 G protein subunit alpha o1
NPEPPS aminopeptidase puromycin sensitive
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
GAS1 growth arrest specific 1
LEF1 lymphoid enhancer binding factor 1
WNT9A Wnt family member 9A
CALM1 calmodulin 1
MAPK1 mitogen-activated protein kinase 1
STXBP5 syntaxin binding protein 5
CAMK2D calcium/calmodulin dependent protein kinase II delta
CREBBP CREB binding protein
GNAQ G protein subunit alpha q
CAMK2G calcium/calmodulin dependent protein kinase II gamma
EP300 E1A binding protein p300
FZD8 frizzled class receptor 8
CCNYL1 cyclin Y like 1
NRAS NRAS proto-oncogene, GTPase
CA6 carbonic anhydrase 6
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
TCF7 transcription factor 7
MAP2K1 mitogen-activated protein kinase kinase 1
FZD5 frizzled class receptor 5
CLIP3 CAP-Gly domain containing linker protein 3
GSK3B glycogen synthase kinase 3 beta
WNT7B Wnt family member 7B
ADCY5 adenylate cyclase 5
KANSL1 KAT8 regulatory NSL complex subunit 1
TNRC18 trinucleotide repeat containing 18
FZD10 frizzled class receptor 10
NCOA1 nuclear receptor coactivator 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ARID1A AT-rich interaction domain 1A
WNT5B Wnt family member 5B
CTDNEP1 CTD nuclear envelope phosphatase 1
Symbol Function*
TYR tyrosinase
TYRP1 tyrosinase related protein 1
KITLG KIT ligand
PRKACA protein kinase cAMP-activated catalytic subunit alpha
KIT KIT proto-oncogene, receptor tyrosine kinase
ADCY5 adenylate cyclase 5
EDNRB endothelin receptor type B
GNAS GNAS complex locus
RAB5A RAB5A, member RAS oncogene family
MITF melanocyte inducing transcription factor
GNAI2 G protein subunit alpha i2
BICRAL BRD4 interacting chromatin remodeling complex associated protein like
CAP1 cyclase associated actin cytoskeleton regulatory protein 1
CTNNB1 catenin beta 1
TAF4 TATA-box binding protein associated factor 4
ADCY6 adenylate cyclase 6
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
LEF1 lymphoid enhancer binding factor 1
POLR2A RNA polymerase II subunit A
CREBBP CREB binding protein
CALM1 calmodulin 1
GPM6B glycoprotein M6B
CDC42EP1 CDC42 effector protein 1
TCF7 transcription factor 7
WNT9A Wnt family member 9A
FZD1 frizzled class receptor 1
CYP1B1 cytochrome P450 family 1 subfamily B member 1
WNT2B Wnt family member 2B
CREB3L1 cAMP responsive element binding protein 3 like 1
FKBP8 FKBP prolyl isomerase 8
FZD4 frizzled class receptor 4
DCT dopachrome tautomerase
FZD10 frizzled class receptor 10
TCF7L2 transcription factor 7 like 2
CALML5 calmodulin like 5
NKD1 NKD inhibitor of WNT signaling pathway 1
ADCY7 adenylate cyclase 7
ARID1A AT-rich interaction domain 1A
TRPM1 transient receptor potential cation channel subfamily M member 1
NYNRIN NYN domain and retroviral integrase containing
PRKCA protein kinase C alpha
CREB3L2 cAMP responsive element binding protein 3 like 2
CAMK2D calcium/calmodulin dependent protein kinase II delta
ERN1 endoplasmic reticulum to nucleus signaling 1
MAP2K2 mitogen-activated protein kinase kinase 2
TCF7L1 transcription factor 7 like 1
WNT2 Wnt family member 2
C18H11orf24 chromosome 18 C11orf24 homolog
FAM124A family with sequence similarity 124 member A
EP300 E1A binding protein p300
SPEN spen family transcriptional repressor
PLCB2 phospholipase C beta 2
LOC102151831 keratin-associated protein 3-3
LOC102153034 calmodulin-like protein 3
BTK Bruton tyrosine kinase
LOC119870648 pantetheinase-like
Symbol Function*
TYRP1 tyrosinase related protein 1
TYR tyrosinase
HRAS HRas proto-oncogene, GTPase
KRAS KRAS proto-oncogene, GTPase
BCL2L2 BCL2 like 2
MAP2K1 mitogen-activated protein kinase kinase 1
GSK3B glycogen synthase kinase 3 beta
CAMK2A calcium/calmodulin dependent protein kinase II alpha
TNS1 tensin 1
KMT2E lysine methyltransferase 2E (inactive)
ZBTB34 zinc finger and BTB domain containing 34
MAPK1 mitogen-activated protein kinase 1
SCN4B sodium voltage-gated channel beta subunit 4
DCP1A decapping mRNA 1A
TRIM72 tripartite motif containing 72
EP300 E1A binding protein p300
NAPA NSF attachment protein alpha
LY9 lymphocyte antigen 9
TCF7L1 transcription factor 7 like 1
WNT16 Wnt family member 16
PLCB2 phospholipase C beta 2
ARID1B AT-rich interaction domain 1B
CALM3 calmodulin 3
ADCY6 adenylate cyclase 6
LOC101091541 phosphatidylinositol phosphatase PTPRQ
PMEL premelanosome protein
GNAI1 G protein subunit alpha i1
FZD4 frizzled class receptor 4
WNT10B Wnt family member 10B
ADCY7 adenylate cyclase 7
WNT1 Wnt family member 1
ADCY2 adenylate cyclase 2
CREBBP CREB binding protein
FLRT3 fibronectin leucine rich transmembrane protein 3
WNT4 Wnt family member 4
RALGAPB Ral GTPase activating protein non-catalytic subunit beta
KANK2 KN motif and ankyrin repeat domains 2
CAMK2G calcium/calmodulin dependent protein kinase II gamma
MTMR1 myotubularin related protein 1
CAMK2B calcium/calmodulin dependent protein kinase II beta
CALML4 calmodulin like 4
CREB3L2 cAMP responsive element binding protein 3 like 2
ADCY5 adenylate cyclase 5
CLCA2 chloride channel accessory 2
GPATCH8 G-patch domain containing 8
LOC102902667 calmodulin-like
LOC111556187 calmodulin-like protein 4


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