KEGG 05142 Chagas disease
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05142 Chagas disease 33
hsa05417 Lipid and atherosclerosis 20
hsa05163 Human cytomegalovirus infection 18
hsa04380 Osteoclast differentiation 17
hsa04620 Toll-like receptor signaling pathway 17
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu05142 Chagas disease 56
mmu05417 Lipid and atherosclerosis 39
mmu05200 Pathways in cancer 36
mmu05170 Human immunodeficiency virus 1 infection 35
mmu04010 MAPK signaling pathway 32
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05142 Chagas disease 42
rno04620 Toll-like receptor signaling pathway 23
rno05417 Lipid and atherosclerosis 23
rno05135 Yersinia infection 22
rno05171 Coronavirus disease - COVID-19 22
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05142 Chagas disease 47
mcc05417 Lipid and atherosclerosis 30
mcc04620 Toll-like receptor signaling pathway 30
mcc05135 Yersinia infection 29
mcc05170 Human immunodeficiency virus 1 infection 26
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa05142 Chagas disease 30
cfa05417 Lipid and atherosclerosis 21
cfa05162 Measles 19
cfa05169 Epstein-Barr virus infection 19
cfa04620 Toll-like receptor signaling pathway 18
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca05142 Chagas disease 32
fca04620 Toll-like receptor signaling pathway 21
fca05417 Lipid and atherosclerosis 20
fca05133 Pertussis 18
fca05171 Coronavirus disease - COVID-19 18
Gene list in the network
Symbol Function*
AKT2 AKT serine/threonine kinase 2
FASLG Fas ligand
BCL3 BCL3 transcription coactivator
C1QA complement C1q A chain
C1QB complement C1q B chain
C1QC complement C1q C chain
CD2 CD2 molecule
CD3D CD3d molecule
CD3E CD3e molecule
CD3G CD3g molecule
CD247 CD247 molecule
CD5 CD5 molecule
CMKLR1 chemerin chemokine-like receptor 1
MAPK14 mitogen-activated protein kinase 14
DUSP1 dual specificity phosphatase 1
FOLR2 folate receptor beta
FOS Fos proto-oncogene, AP-1 transcription factor subunit
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
FPR3 formyl peptide receptor 3
GNAS GNAS complex locus
CXCL2 C-X-C motif chemokine ligand 2
GTF2E2 general transcription factor IIE subunit 2
GZMH granzyme H
GZMA granzyme A
GZMB granzyme B
IFNG interferon gamma
IL1A interleukin 1 alpha
IL1B interleukin 1 beta
IL2RG interleukin 2 receptor subunit gamma
IL6 interleukin 6
CXCL8 C-X-C motif chemokine ligand 8
IL10 interleukin 10
JUN Jun proto-oncogene, AP-1 transcription factor subunit
LCK LCK proto-oncogene, Src family tyrosine kinase
MSR1 macrophage scavenger receptor 1
PPP2CB protein phosphatase 2 catalytic subunit beta
PPP2R2A protein phosphatase 2 regulatory subunit Balpha
PPP2R2B protein phosphatase 2 regulatory subunit Bbeta
MAPK11 mitogen-activated protein kinase 11
PTGS2 prostaglandin-endoperoxide synthase 2
RELA RELA proto-oncogene, NF-kB subunit
MAPK12 mitogen-activated protein kinase 12
CCL2 C-C motif chemokine ligand 2
CCL3 C-C motif chemokine ligand 3
CCL3L1 C-C motif chemokine ligand 3 like 1
CCL4 C-C motif chemokine ligand 4
CCL5 C-C motif chemokine ligand 5
CCL18 C-C motif chemokine ligand 18
MAP2K4 mitogen-activated protein kinase kinase 4
SIGLEC1 sialic acid binding Ig like lectin 1
TNF tumor necrosis factor
TNFRSF1A TNF receptor superfamily member 1A
USF2 upstream transcription factor 2, c-fos interacting
GRAP2 GRB2 related adaptor protein 2
SMNDC1 survival motor neuron domain containing 1
LILRB5 leukocyte immunoglobulin like receptor B5
SLCO2B1 solute carrier organic anion transporter family member 2B1
VSIG4 V-set and immunoglobulin domain containing 4
MS4A4A membrane spanning 4-domains A4A
CAB39 calcium binding protein 39
TREM2 triggering receptor expressed on myeloid cells 2
SIRPG signal regulatory protein gamma
PPP2R2D protein phosphatase 2 regulatory subunit Bdelta
SLAMF8 SLAM family member 8
TNIP3 TNFAIP3 interacting protein 3
TICAM1 toll like receptor adaptor molecule 1
LINC00861 long intergenic non-protein coding RNA 861
LOC105379634 uncharacterized LOC105379634
LOC107987437 uncharacterized LOC107987437
Symbol Function*
Aif1 allograft inflammatory factor 1
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Atf3 activating transcription factor 3
C1qa complement component 1, q subcomponent, alpha polypeptide
C1qb complement component 1, q subcomponent, beta polypeptide
C1qc complement component 1, q subcomponent, C chain
Casp8 caspase 8
Runx1 runt related transcription factor 1
Cd14 CD14 antigen
Cd2 CD2 antigen
Cd3d CD3 antigen, delta polypeptide
Cd3e CD3 antigen, epsilon polypeptide
Cd3g CD3 antigen, gamma polypeptide
Cd247 CD247 antigen
Cd8a CD8 antigen, alpha chain
Cd8b1 CD8 antigen, beta chain 1
Ch25h cholesterol 25-hydroxylase
Csf1r colony stimulating factor 1 receptor
Adgre1 adhesion G protein-coupled receptor E1
Fas Fas (TNF receptor superfamily member 6)
Fasl Fas ligand (TNF superfamily, member 6)
Fcgr1 Fc receptor, IgG, high affinity I
Fos FBJ osteosarcoma oncogene
Gna11 guanine nucleotide binding protein, alpha 11
Gna15 guanine nucleotide binding protein, alpha 15
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3
Gnb2 guanine nucleotide binding protein (G protein), beta 2
Cxcl1 chemokine (C-X-C motif) ligand 1
Gzmk granzyme K
Ifng interferon gamma
Ccn1 cellular communication network factor 1
Ikbkg inhibitor of kappaB kinase gamma
Il1b interleukin 1 beta
Irak1 interleukin-1 receptor-associated kinase 1
Il2 interleukin 2
Il6 interleukin 6
Itk IL2 inducible T cell kinase
Jun jun proto-oncogene
Klrc1 killer cell lectin-like receptor subfamily C, member 1
Kng1 kininogen 1
Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
Lat linker for activation of T cells
Lck lymphocyte protein tyrosine kinase
Xcl1 chemokine (C motif) ligand 1
Ly96 lymphocyte antigen 96
Smad2 SMAD family member 2
Mertk MER proto-oncogene tyrosine kinase
Myd88 myeloid differentiation primary response gene 88
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Osm oncostatin M
Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1
Plcb2 phospholipase C, beta 2
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Mapk11 mitogen-activated protein kinase 11
Dusp1 dual specificity phosphatase 1
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1
Ccl12 chemokine (C-C motif) ligand 12
Ccl2 chemokine (C-C motif) ligand 2
Ccl3 chemokine (C-C motif) ligand 3
Ccl4 chemokine (C-C motif) ligand 4
Ccl7 chemokine (C-C motif) ligand 7
Cxcl2 chemokine (C-X-C motif) ligand 2
Sh2d1a SH2 domain containing 1A
Stat3 signal transducer and activator of transcription 3
Tgfb1 transforming growth factor, beta 1
Tgfb2 transforming growth factor, beta 2
Tgfb3 transforming growth factor, beta 3
Tgfbr2 transforming growth factor, beta receptor II
Thy1 thymus cell antigen 1, theta
Tlr4 toll-like receptor 4
Tnf tumor necrosis factor
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a
Traf6 TNF receptor-associated factor 6
Zap70 zeta-chain (TCR) associated protein kinase
Tlr2 toll-like receptor 2
Map2k4 mitogen-activated protein kinase kinase 4
Mapk1 mitogen-activated protein kinase 1
Mapk10 mitogen-activated protein kinase 10
Mapk14 mitogen-activated protein kinase 14
Mapk3 mitogen-activated protein kinase 3
Mapk9 mitogen-activated protein kinase 9
Mapk12 mitogen-activated protein kinase 12
Ppp2r2d protein phosphatase 2, regulatory subunit B, delta
Shoc2 Shoc2, leucine rich repeat scaffold protein
Rnf14 ring finger protein 14
Tbx21 T-box 21
Bcl11b B cell leukemia/lymphoma 11B
Fetub fetuin beta
Gpalpp1 GPALPP motifs containing 1
Snx4 sorting nexin 4
Ppp2r2b protein phosphatase 2, regulatory subunit B, beta
Cxcr6 chemokine (C-X-C motif) receptor 6
Gpr84 G protein-coupled receptor 84
Cd96 CD96 antigen
Csnk1g2 casein kinase 1, gamma 2
Hdac10 histone deacetylase 10
Nlrp3 NLR family, pyrin domain containing 3
Kcnk13 potassium channel, subfamily K, member 13
Gstp3 glutathione S-transferase pi 3
Kng2 kininogen 2
Bin2 bridging integrator 2
Symbol Function*
Il1a interleukin 1 alpha
Il1b interleukin 1 beta
Il6 interleukin 6
Jun Jun proto-oncogene, AP-1 transcription factor subunit
Nos2 nitric oxide synthase 2
Serpine1 serpin family E member 1
Ppp2ca protein phosphatase 2 catalytic subunit alpha
Ppp2cb protein phosphatase 2 catalytic subunit beta
Ccl2 C-C motif chemokine ligand 2
Tnf tumor necrosis factor
Kng2 kininogen 2
Cd8b CD8b molecule
Kng2l1 kininogen 2-like 1
Bdkrb2 bradykinin receptor B2
Anxa3 annexin A3
Cd247 Cd247 molecule
Atf3 activating transcription factor 3
Nfkbia NFKB inhibitor alpha
Ccl3 C-C motif chemokine ligand 3
Cd28 Cd28 molecule
Cd3d CD3d molecule
Cd69 Cd69 molecule
Tlr4 toll-like receptor 4
C1qb complement C1q B chain
Ctss cathepsin S
Mapk9 mitogen-activated protein kinase 9
Gnao1 G protein subunit alpha o1
Cd5 Cd5 molecule
Vapa VAMP associated protein A
Mapk12 mitogen-activated protein kinase 12
Pik3r3 phosphoinositide-3-kinase regulatory subunit 3
Ccn2 cellular communication network factor 2
Cfi complement factor I
Zfp36 zinc finger protein 36
Nfkb1 nuclear factor kappa B subunit 1
Tgfb2 transforming growth factor, beta 2
Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta
Cxcr3 C-X-C motif chemokine receptor 3
Cxcl2 C-X-C motif chemokine ligand 2
Ifngr1 interferon gamma receptor 1
Ccl4 C-C motif chemokine ligand 4
Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma
Fgl1 fibrinogen-like 1
Tfpi2 tissue factor pathway inhibitor 2
Skap1 src kinase associated phosphoprotein 1
Map2k4 mitogen activated protein kinase kinase 4
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Ccl7 C-C motif chemokine ligand 7
Ccl12 chemokine (C-C motif) ligand 12
Kng1 kininogen 1
Mapkapk2 MAPK activated protein kinase 2
Folr2 folate receptor beta
Ctsw cathepsin W
Calhm6 calcium homeostasis modulator family member 6
Gem GTP binding protein overexpressed in skeletal muscle
C1qa complement C1q A chain
Cd3g CD3g molecule
Zap70 zeta chain of T cell receptor associated protein kinase 70
Tlr6 toll-like receptor 6
Rela RELA proto-oncogene, NF-kB subunit
Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Nfkb2 nuclear factor kappa B subunit 2
Rarres1 retinoic acid receptor responder 1
Lck LCK proto-oncogene, Src family tyrosine kinase
Fos Fos proto-oncogene, AP-1 transcription factor subunit
Cd3e CD3e molecule
Ccrl2 C-C motif chemokine receptor like 2
Paqr8 progestin and adipoQ receptor family member 8
Tlr7 toll-like receptor 7
Tlr9 toll-like receptor 9
Ifngr2 interferon gamma receptor 2
Dusp8 dual specificity phosphatase 8
C1qc complement C1q C chain
Itk IL2-inducible T-cell kinase
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Ly96 lymphocyte antigen 96
Ier2 immediate early response 2
Cd2 Cd2 molecule
Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein
Gimap7 GTPase, IMAP family member 7
Cd27 CD27 molecule
Sit1 signaling threshold regulating transmembrane adaptor 1
Mapk11 mitogen-activated protein kinase 11
Relb RELB proto-oncogene, NF-kB subunit
LOC102554317 uncharacterized LOC102554317
Symbol Function*
CCL2 C-C motif chemokine ligand 2
CCL5 C-C motif chemokine ligand 5
CCR1 C-C motif chemokine receptor 1
STX1A syntaxin 1A
CCL4L1 chemokine (C-C motif) ligand 4-like 1
IFNG interferon gamma
TLR1 toll like receptor 1
TLR2 toll like receptor 2
TICAM1 toll like receptor adaptor molecule 1
TLR6 toll like receptor 6
TLR4 toll like receptor 4
CXCL8 C-X-C motif chemokine ligand 8
CCL3 chemokine (C-C motif) ligand 3
CD2 CD2 molecule
FNDC3B fibronectin type III domain containing 3B
IL10 interleukin 10
TMEM37 transmembrane protein 37
NFKBIA NFKB inhibitor alpha
ACOD1 aconitate decarboxylase 1
LOC696306 T cell receptor beta variable 3-1
MS4A7 membrane spanning 4-domains A7
AKT1 AKT serine/threonine kinase 1
MAPK1 mitogen-activated protein kinase 1
LOC698785 uncharacterized LOC698785
CD3E CD3e molecule
IFNGR2 interferon gamma receptor 2
CD3D CD3d molecule
IRAK1 interleukin 1 receptor associated kinase 1
IL1A interleukin 1 alpha
IRAK4 interleukin 1 receptor associated kinase 4
NLRP3 NLR family pyrin domain containing 3
FOS Fos proto-oncogene, AP-1 transcription factor subunit
LOC702712 hydroxycarboxylic acid receptor 2
DUSP1 dual specificity phosphatase 1
LOC703029 immunoglobulin lambda-1 light chain-like
ARL8B ADP ribosylation factor like GTPase 8B
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
IL1B interleukin 1 beta
PTX3 pentraxin 3
GPNMB glycoprotein nmb
CD3G CD3g molecule
GNAQ G protein subunit alpha q
IL6 interleukin 6
ABI1 abl interactor 1
ITM2A integral membrane protein 2A
C1QA complement C1q A chain
C1QC complement C1q C chain
CHUK component of inhibitor of nuclear factor kappa B kinase complex
VSIG4 V-set and immunoglobulin domain containing 4
NFKB1 nuclear factor kappa B subunit 1
PPP2CA protein phosphatase 2 catalytic subunit alpha
KLF6 Kruppel like factor 6
PPP2R2A protein phosphatase 2 regulatory subunit Balpha
TMEM176A transmembrane protein 176A
RELB RELB proto-oncogene, NF-kB subunit
TNF tumor necrosis factor
MAPK12 mitogen-activated protein kinase 12
MAPK9 mitogen-activated protein kinase 9
MAPK11 mitogen-activated protein kinase 11
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
RELA RELA proto-oncogene, NF-kB subunit
LOC716034 signal-regulatory protein gamma
MAP3K11 mitogen-activated protein kinase kinase kinase 11
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PTGS2 prostaglandin-endoperoxide synthase 2
OSM oncostatin M
MAP2K4 mitogen-activated protein kinase kinase 4
C1QB complement C1q B chain
PPP1R15A protein phosphatase 1 regulatory subunit 15A
FOLR2 folate receptor beta
NCOA1 nuclear receptor coactivator 1
CD5L CD5 molecule like
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
NKG7 natural killer cell granule protein 7
GNA11 G protein subunit alpha 11
GNA15 G protein subunit alpha 15
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
TNFRSF1A TNF receptor superfamily member 1A
MIR147B microRNA mir-147b
IFNGR1 interferon gamma receptor 1
LOC100424766 uncharacterized LOC100424766
LOC100426537 C-C motif chemokine 3-like
LOC100430627 C-C motif chemokine 4
CHPF2 chondroitin polymerizing factor 2
LOC106995258 uncharacterized protein CXorf21-like
LOC106999340 immunoglobulin kappa light chain
LOC106999345 T cell receptor alpha variable 26-1-like
LOC107000845 uncharacterized LOC107000845
LOC114673087 C-C motif chemokine 3-like 1
LOC114677059 uncharacterized LOC114677059
Symbol Function*
CCL5 C-C motif chemokine ligand 5
IL10 interleukin 10
IL1A interleukin 1 alpha
CXCL8 C-X-C motif chemokine ligand 8
NR4A1 nuclear receptor subfamily 4 group A member 1
TNF tumor necrosis factor
GNAS GNAS complex locus
IL1B interleukin 1 beta
CCL2 C-C motif chemokine ligand 2
IL6 interleukin 6
NFKB1 nuclear factor kappa B subunit 1
FASLG Fas ligand
CD3E CD3e molecule
CCL4 chemokine (C-C motif) ligand 4
CCL3 chemokine (C-C motif) ligand 3
CCL8 C-C motif chemokine ligand 8
MPEG1 macrophage expressed 1
PLCB3 phospholipase C beta 3
APOE apolipoprotein E
MAPK8 mitogen-activated protein kinase 8
CHUK component of inhibitor of nuclear factor kappa B kinase complex
LCK LCK proto-oncogene, Src family tyrosine kinase
C1QA complement C1q A chain
LOC478984 low affinity immunoglobulin gamma Fc region receptor III
CD3D CD3d molecule
MVP major vault protein
NFKBIA NFKB inhibitor alpha
SKAP1 src kinase associated phosphoprotein 1
RELA RELA proto-oncogene, NF-kB subunit
EHBP1L1 EH domain binding protein 1 like 1
DPF2 double PHD fingers 2
TNFAIP3 TNF alpha induced protein 3
RELB RELB proto-oncogene, NF-kB subunit
FKBP8 FKBP prolyl isomerase 8
GPR171 G protein-coupled receptor 171
PLTP phospholipid transfer protein
HCAR2 hydroxycarboxylic acid receptor 2
IRAK4 interleukin 1 receptor associated kinase 4
NFKB2 nuclear factor kappa B subunit 2
C1QB complement C1q B chain
C1QC complement C1q C chain
TIMD4 T cell immunoglobulin and mucin domain containing 4
CD3G CD3g molecule
SEPTIN1 septin 1
KCNA3 potassium voltage-gated channel subfamily A member 3
FOS Fos proto-oncogene, AP-1 transcription factor subunit
AKT1 AKT serine/threonine kinase 1
CCL7 C-C motif chemokine ligand 7
CD2 CD2 molecule
LOC607937 T cell receptor alpha variable 9-2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
PVRIG PVR related immunoglobulin domain containing
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
CD247 CD247 molecule
GNAI3 G protein subunit alpha i3
SLC25A24 solute carrier family 25 member 24
TRAF6 TNF receptor associated factor 6
CH25H cholesterol 25-hydroxylase
LOC119874472 growth-regulated protein homolog gamma-like
Symbol Function*
IL10 interleukin 10
IL6 interleukin 6
CCL5 C-C motif chemokine ligand 5
TLR4 toll like receptor 4
TNF tumor necrosis factor
TLR2 toll like receptor 2
CXCL8 C-X-C motif chemokine ligand 8
FOS Fos proto-oncogene, AP-1 transcription factor subunit
IL1A interleukin 1 alpha
IFNG interferon gamma
TGFB1 transforming growth factor beta 1
IL1B interleukin 1 beta
MCP-1 monocyte chemoattractant protein 1
IKBKB inhibitor of nuclear factor kappa B kinase subunit beta
LOC100302540 chemokine (C-C motif) ligand 3-like
LOC100302541 chemokine (C-C motif) ligand 4-like
CD247 CD247 molecule
LOC101081091 C-C motif chemokine 3-like
LOC101081599 cytokine SCM-1 beta
SOCS3 suppressor of cytokine signaling 3
CDK14 cyclin dependent kinase 14
MYH10 myosin heavy chain 10
TICAM1 toll like receptor adaptor molecule 1
CD3D CD3d molecule
LOC101083124 angiotensin-converting enzyme-like protein Ace3
RIPK1 receptor interacting serine/threonine kinase 1
AKT1 AKT serine/threonine kinase 1
CD3G CD3g molecule
GNAI2 G protein subunit alpha i2
IRAK1 interleukin 1 receptor associated kinase 1
NKG7 natural killer cell granule protein 7
PLCB1 phospholipase C beta 1
AKT3 AKT serine/threonine kinase 3
IRAK3 interleukin 1 receptor associated kinase 3
ACE angiotensin I converting enzyme
C1QC complement C1q C chain
LOC101094897 C4b-binding protein alpha chain
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
LOC101095853 folate receptor beta
C1QA complement C1q A chain
C1QB complement C1q B chain
JUN Jun proto-oncogene, AP-1 transcription factor subunit
MBD3 methyl-CpG binding domain protein 3
MPEG1 macrophage expressed 1
TRAF6 TNF receptor associated factor 6
IRAK4 interleukin 1 receptor associated kinase 4
CXCL9 C-X-C motif chemokine ligand 9
SH3BGRL3 SH3 domain binding glutamate rich protein like 3
ZBTB42 zinc finger and BTB domain containing 42


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