KEGG 01522 Endocrine resistance
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa01522 Endocrine resistance 25
hsa05200 Pathways in cancer 20
hsa05224 Breast cancer 17
hsa05161 Hepatitis B 15
hsa05163 Human cytomegalovirus infection 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu01522 Endocrine resistance 26
mmu05200 Pathways in cancer 23
mmu05224 Breast cancer 19
mmu05163 Human cytomegalovirus infection 18
mmu05166 Human T-cell leukemia virus 1 infection 18
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno01522 Endocrine resistance 43
rno05200 Pathways in cancer 35
rno05224 Breast cancer 29
rno05163 Human cytomegalovirus infection 25
rno05166 Human T-cell leukemia virus 1 infection 22
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc01522 Endocrine resistance 27
mcc05200 Pathways in cancer 25
mcc05224 Breast cancer 20
mcc05165 Human papillomavirus infection 17
mcc05207 Chemical carcinogenesis - receptor activation 17
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa01522 Endocrine resistance 25
cfa05200 Pathways in cancer 24
cfa05224 Breast cancer 20
cfa04915 Estrogen signaling pathway 17
cfa05207 Chemical carcinogenesis - receptor activation 16
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca01522 Endocrine resistance 31
fca05200 Pathways in cancer 30
fca05224 Breast cancer 24
fca05163 Human cytomegalovirus infection 21
fca05161 Hepatitis B 20
Gene list in the network
Symbol Function*
AP2A1 adaptor related protein complex 2 subunit alpha 1
AKT2 AKT serine/threonine kinase 2
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATF3 activating transcription factor 3
BAX BCL2 associated X, apoptosis regulator
MAPK14 mitogen-activated protein kinase 14
HBEGF heparin binding EGF like growth factor
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
FDXR ferredoxin reductase
FOS Fos proto-oncogene, AP-1 transcription factor subunit
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
GNAS GNAS complex locus
JAG2 jagged canonical Notch ligand 2
JUN Jun proto-oncogene, AP-1 transcription factor subunit
MDM2 MDM2 proto-oncogene
NOTCH1 notch receptor 1
NOTCH4 notch receptor 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
MAPK11 mitogen-activated protein kinase 11
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK12 mitogen-activated protein kinase 12
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
SRPK1 SRSF protein kinase 1
USF2 upstream transcription factor 2, c-fos interacting
CARM1 coactivator associated arginine methyltransferase 1
ARHGEF15 Rho guanine nucleotide exchange factor 15
ATP11B ATPase phospholipid transporting 11B (putative)
DLL1 delta like canonical Notch ligand 1
RPS27L ribosomal protein S27 like
TRIAP1 TP53 regulated inhibitor of apoptosis 1
DLL4 delta like canonical Notch ligand 4
AEN apoptosis enhancing nuclease
ZNF367 zinc finger protein 367
ADCY4 adenylate cyclase 4
Symbol Function*
Adcy7 adenylate cyclase 7
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Atf3 activating transcription factor 3
Bax BCL2-associated X protein
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21)
Cdkn2a cyclin dependent kinase inhibitor 2A
Cdkn2b cyclin dependent kinase inhibitor 2B
Cdkn2c cyclin dependent kinase inhibitor 2C
Dll1 delta like canonical Notch ligand 1
Dll3 delta like canonical Notch ligand 3
E2f1 E2F transcription factor 1
Fos FBJ osteosarcoma oncogene
Hras Harvey rat sarcoma virus oncogene
Jun jun proto-oncogene
Mbd3 methyl-CpG binding domain protein 3
Notch1 notch 1
Notch3 notch 3
Notch4 notch 4
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Mapk11 mitogen-activated protein kinase 11
Dusp1 dual specificity phosphatase 1
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Trpv2 transient receptor potential cation channel, subfamily V, member 2
Map2k2 mitogen-activated protein kinase kinase 2
Mapk1 mitogen-activated protein kinase 1
Mapk14 mitogen-activated protein kinase 14
Phlda3 pleckstrin homology like domain, family A, member 3
Mapk12 mitogen-activated protein kinase 12
Dll4 delta like canonical Notch ligand 4
Mtch1 mitochondrial carrier 1
Nrarp Notch-regulated ankyrin repeat protein
Robo4 roundabout guidance receptor 4
Csnk1g2 casein kinase 1, gamma 2
Adcy4 adenylate cyclase 4
Tcf19 transcription factor 19
Hdac10 histone deacetylase 10
Arhgef15 Rho guanine nucleotide exchange factor (GEF) 15
Symbol Function*
Erbb2 erb-b2 receptor tyrosine kinase 2
Jun Jun proto-oncogene, AP-1 transcription factor subunit
Nras NRAS proto-oncogene, GTPase
Rb1 RB transcriptional corepressor 1
Tp53 tumor protein p53
Atf3 activating transcription factor 3
Hbegf heparin-binding EGF-like growth factor
Notch1 notch receptor 1
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Igf1r insulin-like growth factor 1 receptor
Jag2 jagged canonical Notch ligand 2
Prkce protein kinase C, epsilon
Notch2 notch receptor 2
Mapk13 mitogen activated protein kinase 13
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Adcy4 adenylate cyclase 4
Cdkn2c cyclin-dependent kinase inhibitor 2C
Ncor1 nuclear receptor co-repressor 1
Notch3 notch receptor 3
Ccnd1 cyclin D1
Map2k2 mitogen activated protein kinase kinase 2
Mapk12 mitogen-activated protein kinase 12
Adcy3 adenylate cyclase 3
Mtpn myotrophin
Mmp2 matrix metallopeptidase 2
Mmp14 matrix metallopeptidase 14
Dll1 delta like canonical Notch ligand 1
Ncoa3 nuclear receptor coactivator 3
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Cdk4 cyclin-dependent kinase 4
Braf B-Raf proto-oncogene, serine/threonine kinase
Bik BCL2-interacting killer
Cdkn1a cyclin-dependent kinase inhibitor 1A
Mapk1 mitogen activated protein kinase 1
Map2k1 mitogen activated protein kinase kinase 1
Ipmk inositol polyphosphate multikinase
Ushbp1 USH1 protein network component harmonin binding protein 1
E2f3 E2F transcription factor 3
Hras HRas proto-oncogene, GTPase
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Fbxo11 F-box protein 11
Rhbdf1 rhomboid 5 homolog 1
Adcy1 adenylate cyclase 1
Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
Phc3 polyhomeotic homolog 3
Dll4 delta like canonical Notch ligand 4
Mlf2 myeloid leukemia factor 2
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Fos Fos proto-oncogene, AP-1 transcription factor subunit
Mdm2 MDM2 proto-oncogene
Dcakd dephospho-CoA kinase domain containing
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Aen apoptosis enhancing nuclease
Relt RELT, TNF receptor
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
E2f1 E2F transcription factor 1
Notch4 notch receptor 4
Tcf19 transcription factor 19
Ier2 immediate early response 2
Med1 mediator complex subunit 1
Nrarp Notch-regulated ankyrin repeat protein
E2f2 E2F transcription factor 2
Mapk11 mitogen-activated protein kinase 11
Ankhd1 ankyrin repeat and KH domain containing 1
Symbol Function*
CDH5 cadherin 5
TRIB1 tribbles pseudokinase 1
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
ASXL2 ASXL transcriptional regulator 2
HBEGF heparin binding EGF like growth factor
STUB1 STIP1 homology and U-box containing protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
HRAS HRas proto-oncogene, GTPase
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
FOS Fos proto-oncogene, AP-1 transcription factor subunit
SP1 Sp1 transcription factor
DUSP1 dual specificity phosphatase 1
B4GALT2 beta-1,4-galactosyltransferase 2
DLL4 delta like canonical Notch ligand 4
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
MAPK3 mitogen-activated protein kinase 3
PRKACB protein kinase cAMP-activated catalytic subunit beta
NOTCH1 notch receptor 1
LOC709988 cyclin-dependent kinase inhibitor 2A
KLF6 Kruppel like factor 6
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
NOTCH2 notch receptor 2
DDB2 damage specific DNA binding protein 2
DLL1 delta like canonical Notch ligand 1
NYNRIN NYN domain and retroviral integrase containing
NOL4L nucleolar protein 4 like
MAPK12 mitogen-activated protein kinase 12
MAPK11 mitogen-activated protein kinase 11
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
JUN Jun proto-oncogene, AP-1 transcription factor subunit
NOTCH4 notch receptor 4
KIAA2026 KIAA2026
BAD BCL2 associated agonist of cell death
CHMP6 charged multivesicular body protein 6
PRKACA protein kinase cAMP-activated catalytic subunit alpha
BAX BCL2 associated X, apoptosis regulator
NOTCH3 notch receptor 3
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
AP1S1 adaptor related protein complex 1 subunit sigma 1
VANGL2 VANGL planar cell polarity protein 2
RPS6KB2 ribosomal protein S6 kinase B2
CTDNEP1 CTD nuclear envelope phosphatase 1
MAP2K2 mitogen-activated protein kinase kinase 2
LOC100424766 uncharacterized LOC100424766
TEAD3 TEA domain transcription factor 3
Symbol Function*
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ESR2 estrogen receptor 2
NRAS NRAS proto-oncogene, GTPase
ERBB2 erb-b2 receptor tyrosine kinase 2
MMP9 matrix metallopeptidase 9
GNAS GNAS complex locus
AKT3 AKT serine/threonine kinase 3
CDKN1A cyclin dependent kinase inhibitor 1A
DDA1 DET1 and DDB1 associated 1
DENND5A DENN domain containing 5A
ATP9A ATPase phospholipid transporting 9A (putative)
ADCY6 adenylate cyclase 6
MAPK8 mitogen-activated protein kinase 8
TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1
NOTCH2 notch receptor 2
GRB2 growth factor receptor bound protein 2
FKBP8 FKBP prolyl isomerase 8
SP1 Sp1 transcription factor
MAPKAPK2 MAPK activated protein kinase 2
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
FOS Fos proto-oncogene, AP-1 transcription factor subunit
KIF26A kinesin family member 26A
AKT1 AKT serine/threonine kinase 1
JAG2 jagged canonical Notch ligand 2
DLL4 delta like canonical Notch ligand 4
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
NOTCH3 notch receptor 3
MAP2K2 mitogen-activated protein kinase kinase 2
SHC2 SHC adaptor protein 2
MATK megakaryocyte-associated tyrosine kinase
ATF3 activating transcription factor 3
COL18A1 collagen type XVIII alpha 1 chain
DLL1 delta like canonical Notch ligand 1
IGFBP3 insulin like growth factor binding protein 3
LOC111094294 uncharacterized LOC111094294
NCOA3 nuclear receptor coactivator 3
Symbol Function*
TP53 tumor protein p53
BCL2 BCL2 apoptosis regulator
FOS Fos proto-oncogene, AP-1 transcription factor subunit
BAD BCL2 associated agonist of cell death
CCND1 cyclin D1
AKT2 AKT serine/threonine kinase 2
MAP2K1 mitogen-activated protein kinase kinase 1
PHF3 PHD finger protein 3
USP4 ubiquitin specific peptidase 4
NCOA3 nuclear receptor coactivator 3
RPRD2 regulation of nuclear pre-mRNA domain containing 2
TNS1 tensin 1
CRKL CRK like proto-oncogene, adaptor protein
MAPK1 mitogen-activated protein kinase 1
AKT1 AKT serine/threonine kinase 1
NOTCH3 notch receptor 3
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
JAG2 jagged canonical Notch ligand 2
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
E2F3 E2F transcription factor 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
MED1 mediator complex subunit 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
STAT5A signal transducer and activator of transcription 5A
ADCY6 adenylate cyclase 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
LIMD1 LIM domain containing 1
PTBP1 polypyrimidine tract binding protein 1
SHC1 SHC adaptor protein 1
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
KAT6A lysine acetyltransferase 6A
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
CDK4 cyclin dependent kinase 4
MTOR mechanistic target of rapamycin kinase
MTMR1 myotubularin related protein 1
FLNB filamin B
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
GPR137 G protein-coupled receptor 137
ZNF445 zinc finger protein 445
FLII FLII actin remodeling protein
SP1 Sp1 transcription factor
MAP2K2 mitogen-activated protein kinase kinase 2
ADCY5 adenylate cyclase 5
RB1 RB transcriptional corepressor 1
MAPK11 mitogen-activated protein kinase 11


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