KEGG 04919 Thyroid hormone signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04919 Thyroid hormone signaling pathway 33
hsa04022 cGMP-PKG signaling pathway 13
hsa04024 cAMP signaling pathway 13
hsa04261 Adrenergic signaling in cardiomyocytes 12
hsa05200 Pathways in cancer 12
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04919 Thyroid hormone signaling pathway 46
mmu05200 Pathways in cancer 24
mmu05165 Human papillomavirus infection 21
mmu05205 Proteoglycans in cancer 20
mmu04066 HIF-1 signaling pathway 20
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04919 Thyroid hormone signaling pathway 46
rno05200 Pathways in cancer 22
rno05165 Human papillomavirus infection 17
rno05205 Proteoglycans in cancer 16
rno04024 cAMP signaling pathway 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04919 Thyroid hormone signaling pathway 45
mcc05200 Pathways in cancer 19
mcc05165 Human papillomavirus infection 17
mcc05205 Proteoglycans in cancer 16
mcc04024 cAMP signaling pathway 16
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04919 Thyroid hormone signaling pathway 43
cfa05200 Pathways in cancer 20
cfa04024 cAMP signaling pathway 16
cfa04261 Adrenergic signaling in cardiomyocytes 16
cfa04922 Glucagon signaling pathway 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04919 Thyroid hormone signaling pathway 47
fca05200 Pathways in cancer 20
fca05163 Human cytomegalovirus infection 13
fca05165 Human papillomavirus infection 13
fca05205 Proteoglycans in cancer 13
Gene list in the network
Symbol Function*
ACTB actin beta
ACTG1 actin gamma 1
AKT2 AKT serine/threonine kinase 2
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
ATP1A2 ATPase Na+/K+ transporting subunit alpha 2
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
ATP1B3 ATPase Na+/K+ transporting subunit beta 3
ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
CASQ1 calsequestrin 1
CREBBP CREB binding protein
EP300 E1A binding protein p300
MYH6 myosin heavy chain 6
MYH7 myosin heavy chain 7
NOTCH1 notch receptor 1
P2RX1 purinergic receptor P2X 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
PLCB2 phospholipase C beta 2
MED1 mediator complex subunit 1
MAPK3 mitogen-activated protein kinase 3
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
PYGM glycogen phosphorylase, muscle associated
RXRA retinoid X receptor alpha
THRA thyroid hormone receptor alpha
TPM4 tropomyosin 4
USF2 upstream transcription factor 2, c-fos interacting
NCOA3 nuclear receptor coactivator 3
NCOA1 nuclear receptor coactivator 1
HDAC3 histone deacetylase 3
MED14 mediator complex subunit 14
NCOR1 nuclear receptor corepressor 1
WDR1 WD repeat domain 1
MED13 mediator complex subunit 13
TSHZ1 teashirt zinc finger homeobox 1
BCKDK branched chain keto acid dehydrogenase kinase
NCOA2 nuclear receptor coactivator 2
MED13L mediator complex subunit 13L
BICRAL BRD4 interacting chromatin remodeling complex associated protein like
SIN3A SIN3 transcription regulator family member A
CDK12 cyclin dependent kinase 12
BCOR BCL6 corepressor
KMT2C lysine methyltransferase 2C
C10orf71 chromosome 10 open reading frame 71
TUBB tubulin beta class I
Symbol Function*
Actb actin, beta
Actg1 actin, gamma, cytoplasmic 1
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Aldoa aldolase A, fructose-bisphosphate
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Cfl1 cofilin 1, non-muscle
Coro1a coronin, actin binding protein 1A
Crebbp CREB binding protein
Hk1 hexokinase 1
Hras Harvey rat sarcoma virus oncogene
Itgav integrin alpha V
Mbd3 methyl-CpG binding domain protein 3
Aff1 AF4/FMR2 family, member 1
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha
Ncoa1 nuclear receptor coactivator 1
Ncoa2 nuclear receptor coactivator 2
Notch1 notch 1
Notch3 notch 3
Nras neuroblastoma ras oncogene
Pdpk1 3-phosphoinositide dependent protein kinase 1
Pfkl phosphofructokinase, liver, B-type
Pfkm phosphofructokinase, muscle
Pgam1 phosphoglycerate mutase 1
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
Pik3r2 phosphoinositide-3-kinase regulatory subunit 2
Prkca protein kinase C, alpha
Prkcb protein kinase C, beta
Prkcg protein kinase C, gamma
Plcd4 phospholipase C, delta 4
Pln phospholamban
Pygm muscle glycogen phosphorylase
Ncor1 nuclear receptor co-repressor 1
Atxn1 ataxin 1
Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Syn1 synapsin I
Thra thyroid hormone receptor alpha
Tsc2 TSC complex subunit 2
Map2k1 mitogen-activated protein kinase kinase 1
Map2k2 mitogen-activated protein kinase kinase 2
Nfat5 nuclear factor of activated T cells 5
Pfkp phosphofructokinase, platelet
Foxo1 forkhead box O1
Mtch1 mitochondrial carrier 1
Gsk3b glycogen synthase kinase 3 beta
Mtor mechanistic target of rapamycin kinase
Med12 mediator complex subunit 12
Nrarp Notch-regulated ankyrin repeat protein
Ubr4 ubiquitin protein ligase E3 component n-recognin 4
Rap2b RAP2B, member of RAS oncogene family
Kmt2b lysine (K)-specific methyltransferase 2B
Med13l mediator complex subunit 13-like
Tbl1xr1 transducin (beta)-like 1X-linked receptor 1
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
Csnk1g2 casein kinase 1, gamma 2
Pcnx3 pecanex homolog 3
Foxp1 forkhead box P1
Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta
Bptf bromodomain PHD finger transcription factor
Med16 mediator complex subunit 16
Taok1 TAO kinase 1
Synrg synergin, gamma
Bag6 BCL2-associated athanogene 6
Gatad2b GATA zinc finger domain containing 2B
Kmt2c lysine (K)-specific methyltransferase 2C
Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
Kat6a K(lysine) acetyltransferase 6A
Nrip1 nuclear receptor interacting protein 1
Med13 mediator complex subunit 13
Ep300 E1A binding protein p300
Rc3h1 RING CCCH (C3H) domains 1
Gm31251 predicted gene, 31251
Symbol Function*
Atp1a1 ATPase Na+/K+ transporting subunit alpha 1
Atp1a2 ATPase Na+/K+ transporting subunit alpha 2
Atp1a3 ATPase Na+/K+ transporting subunit alpha 3
Atp1b2 ATPase Na+/K+ transporting subunit beta 2
Nras NRAS proto-oncogene, GTPase
Pgam1 phosphoglycerate mutase 1
Plcd1 phospholipase C, delta 1
Prkcg protein kinase C, gamma
Pygm glycogen phosphorylase, muscle associated
Slc2a1 solute carrier family 2 member 1
Slc9a1 solute carrier family 9 member A1
Tp53 tumor protein p53
Tsc2 TSC complex subunit 2
Hk1 hexokinase 1
Notch1 notch receptor 1
Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
Agrn agrin
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Atp1b1 ATPase Na+/K+ transporting subunit beta 1
Plcg1 phospholipase C, gamma 1
Pfkl phosphofructokinase, liver type
Plcb3 phospholipase C beta 3
Pik3r2 phosphoinositide-3-kinase regulatory subunit 2
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Crebbp CREB binding protein
Ncor1 nuclear receptor co-repressor 1
Mtor mechanistic target of rapamycin kinase
Notch3 notch receptor 3
Map2k2 mitogen activated protein kinase kinase 2
Pfkp phosphofructokinase, platelet
Pi4ka phosphatidylinositol 4-kinase alpha
Pfkm phosphofructokinase, muscle
Mtpn myotrophin
Pdpk1 3-phosphoinositide dependent protein kinase-1
Thra thyroid hormone receptor alpha
Actb actin, beta
Rxrg retinoid X receptor gamma
Gsk3b glycogen synthase kinase 3 beta
Foxo1 forkhead box O1
Hdac3 histone deacetylase 3
Ncoa3 nuclear receptor coactivator 3
Plce1 phospholipase C, epsilon 1
Mapk1 mitogen activated protein kinase 1
Acsl6 acyl-CoA synthetase long-chain family member 6
Plcd4 phospholipase C, delta 4
Palm paralemmin
Map2k1 mitogen activated protein kinase kinase 1
Ep300 E1A binding protein p300
Ero1a endoplasmic reticulum oxidoreductase 1 alpha
Fndc5 fibronectin type III domain containing 5
Plcd3 phospholipase C, delta 3
Usp42 ubiquitin specific peptidase 42
Hras HRas proto-oncogene, GTPase
Arid1a AT-rich interaction domain 1A
Raver1 ribonucleoprotein, PTB-binding 1
Med16 mediator complex subunit 16
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Ipo9 importin 9
Fam193a family with sequence similarity 193, member A
Ap1m1 adaptor related protein complex 1 subunit mu 1
Palmd palmdelphin
Mlf2 myeloid leukemia factor 2
Focad focadhesin
Tln2 talin 2
Usp7 ubiquitin specific peptidase 7
Med13l mediator complex subunit 13L
Ehmt2 euchromatic histone lysine methyltransferase 2
Szt2 SZT2 subunit of KICSTOR complex
Mbd3 methyl-CpG binding domain protein 3
Sin3a SIN3 transcription regulator family member A
Dock6 dedicator of cytokinesis 6
Nrarp Notch-regulated ankyrin repeat protein
Oaz2 ornithine decarboxylase antizyme 2
Med24 mediator complex subunit 24
Med12 mediator complex subunit 12
Setd1b SET domain containing 1B, histone lysine methyltransferase
Kmt2d lysine methyltransferase 2D
Ankhd1 ankyrin repeat and KH domain containing 1
Symbol Function*
ACTB actin beta
NCOA2 nuclear receptor coactivator 2
FOXP1 forkhead box P1
DNAJC5 DnaJ heat shock protein family (Hsp40) member C5
ASXL2 ASXL transcriptional regulator 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
SPEN spen family transcriptional repressor
NCOR1 nuclear receptor corepressor 1
STUB1 STIP1 homology and U-box containing protein 1
KMT2E lysine methyltransferase 2E (inactive)
PDPK1 3-phosphoinositide dependent protein kinase 1
MED1 mediator complex subunit 1
KAT2B lysine acetyltransferase 2B
MAPK1 mitogen-activated protein kinase 1
HRAS HRas proto-oncogene, GTPase
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
MED14 mediator complex subunit 14
FOXO1 forkhead box O1
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
RERGL RERG like
SLC16A2 solute carrier family 16 member 2
B4GALT2 beta-1,4-galactosyltransferase 2
RCAN2 regulator of calcineurin 2
CREBBP CREB binding protein
SLCO1C1 solute carrier organic anion transporter family member 1C1
ANKRD17 ankyrin repeat domain 17
LOC705671 actin, cytoplasmic 2-like
SIN3A SIN3 transcription regulator family member A
EP300 E1A binding protein p300
ATP1A3 ATPase Na+/K+ transporting subunit alpha 3
NCOA6 nuclear receptor coactivator 6
MAPK3 mitogen-activated protein kinase 3
RABL6 RAB, member RAS oncogene family like 6
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
PRKACB protein kinase cAMP-activated catalytic subunit beta
NOTCH1 notch receptor 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
RB1CC1 RB1 inducible coiled-coil 1
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
TAOK1 TAO kinase 1
CLTC clathrin heavy chain
MED13 mediator complex subunit 13
WDR1 WD repeat domain 1
SORL1 sortilin related receptor 1
GSK3B glycogen synthase kinase 3 beta
BAZ2A bromodomain adjacent to zinc finger domain 2A
ACTG1 actin gamma 1
NOTCH2 notch receptor 2
MED13L mediator complex subunit 13L
NOL4L nucleolar protein 4 like
PLCD3 phospholipase C delta 3
ATP1B3 ATPase Na+/K+ transporting subunit beta 3
KANSL1 KAT8 regulatory NSL complex subunit 1
TNRC18 trinucleotide repeat containing 18
ITGB3 integrin subunit beta 3
BAD BCL2 associated agonist of cell death
PRKCA protein kinase C alpha
NCOA1 nuclear receptor coactivator 1
APLP2 amyloid beta precursor like protein 2
BRPF3 bromodomain and PHD finger containing 3
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
ARID1A AT-rich interaction domain 1A
ATP1A2 ATPase Na+/K+ transporting subunit alpha 2
MAP2K2 mitogen-activated protein kinase kinase 2
RXRA retinoid X receptor alpha
PFKL phosphofructokinase, liver type
PFKP phosphofructokinase, platelet
MTOR mechanistic target of rapamycin kinase
PCDH1 protocadherin 1
Symbol Function*
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ACTB actin beta
THRA thyroid hormone receptor alpha
MYL2 myosin light chain 2
MYH7 myosin heavy chain 7
ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
MYC MYC proto-oncogene, bHLH transcription factor
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
RAB5A RAB5A, member RAS oncogene family
PLN phospholamban
AKT3 AKT serine/threonine kinase 3
AKT2 AKT serine/threonine kinase 2
BICRAL BRD4 interacting chromatin remodeling complex associated protein like
NCOA1 nuclear receptor coactivator 1
PLCB3 phospholipase C beta 3
DENND5A DENN domain containing 5A
CTNNB1 catenin beta 1
KAT2B lysine acetyltransferase 2B
PLCB4 phospholipase C beta 4
TAF4 TATA-box binding protein associated factor 4
FOXO1 forkhead box O1
DHX37 DEAH-box helicase 37
PGAM1 phosphoglycerate mutase 1
PFKP phosphofructokinase, platelet
SLC9A1 solute carrier family 9 member A1
SIN3A SIN3 transcription regulator family member A
PLCD4 phospholipase C delta 4
POLR2A RNA polymerase II subunit A
NCOR1 nuclear receptor corepressor 1
ENO1 enolase 1
LOC479773 Snf2 related CREBBP activator protein
CREBBP CREB binding protein
PDPK1 3-phosphoinositide dependent protein kinase 1
MED1 mediator complex subunit 1
MED13 mediator complex subunit 13
ARHGAP25 Rho GTPase activating protein 25
SLC2A1 solute carrier family 2 member 1
NOTCH2 notch receptor 2
EHBP1L1 EH domain binding protein 1 like 1
FKBP8 FKBP prolyl isomerase 8
NCLN nicalin
MED16 mediator complex subunit 16
PLCB1 phospholipase C beta 1
NCOA2 nuclear receptor coactivator 2
ARID1A AT-rich interaction domain 1A
PFKL phosphofructokinase, liver type
ATP1A4 ATPase Na+/K+ transporting subunit alpha 4
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PLCG2 phospholipase C gamma 2
MAPKAPK2 MAPK activated protein kinase 2
MIDEAS mitotic deacetylase associated SANT domain protein
AKT1 AKT serine/threonine kinase 1
KAT2A lysine acetyltransferase 2A
RXRA retinoid X receptor alpha
ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
USP22 ubiquitin specific peptidase 22
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
MYOZ3 myozenin 3
MAP2K2 mitogen-activated protein kinase kinase 2
EP300 E1A binding protein p300
SP2 Sp2 transcription factor
SPEN spen family transcriptional repressor
KMT2B lysine methyltransferase 2B
MED12 mediator complex subunit 12
TLN1 talin 1
CRAMP1 cramped chromatin regulator homolog 1
CPNE3 copine 3
KANSL1 KAT8 regulatory NSL complex subunit 1
Symbol Function*
KRAS KRAS proto-oncogene, GTPase
SLC2A1 solute carrier family 2 member 1
ACTG1 actin gamma 1
MYC MYC proto-oncogene, bHLH transcription factor
TTN titin
RXRG retinoid X receptor gamma
MAP2K1 mitogen-activated protein kinase kinase 1
GSK3B glycogen synthase kinase 3 beta
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
CDK14 cyclin dependent kinase 14
PITPNM1 phosphatidylinositol transfer protein membrane associated 1
SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha
SPEN spen family transcriptional repressor
MYH10 myosin heavy chain 10
SETD5 SET domain containing 5
TSC2 TSC complex subunit 2
USP4 ubiquitin specific peptidase 4
NCOA3 nuclear receptor coactivator 3
ATP1A3 ATPase Na+/K+ transporting subunit alpha 3
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
SBF1 SET binding factor 1
AGO2 argonaute RISC catalytic component 2
KMT2E lysine methyltransferase 2E (inactive)
MED14 mediator complex subunit 14
RAB3A RAB3A, member RAS oncogene family
BAZ2A bromodomain adjacent to zinc finger domain 2A
ZBTB34 zinc finger and BTB domain containing 34
MAPK1 mitogen-activated protein kinase 1
PLCD1 phospholipase C delta 1
DCP1A decapping mRNA 1A
EP300 E1A binding protein p300
RIC1 RIC1 homolog, RAB6A GEF complex partner 1
SLC9A1 solute carrier family 9 member A1
PFKM phosphofructokinase, muscle
MED27 mediator complex subunit 27
MED1 mediator complex subunit 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
MED12 mediator complex subunit 12
PLXNA1 plexin A1
PFKL phosphofructokinase, liver type
ARID1B AT-rich interaction domain 1B
MED13 mediator complex subunit 13
PLD2 phospholipase D2
PLCB1 phospholipase C beta 1
PHF8 PHD finger protein 8
AKT3 AKT serine/threonine kinase 3
PLCB3 phospholipase C beta 3
ENO1 enolase 1
MED16 mediator complex subunit 16
CREBBP CREB binding protein
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
WNT4 Wnt family member 4
NCOR1 nuclear receptor corepressor 1
MYH6 myosin heavy chain 6
NT5C1A 5'-nucleotidase, cytosolic IA
FOXO1 forkhead box O1
MYH7 myosin heavy chain 7
LOC101096785 sodium/potassium-transporting ATPase subunit alpha-2
RERE arginine-glutamic acid dipeptide repeats
LOC101097072 ATP-dependent 6-phosphofructokinase, platelet type
RALGAPB Ral GTPase activating protein non-catalytic subunit beta
MTOR mechanistic target of rapamycin kinase
MTMR1 myotubularin related protein 1
POLR2A RNA polymerase II subunit A
ACTB actin beta
ZFP36L2 ZFP36 ring finger protein like 2
SIN3A SIN3 transcription regulator family member A
PGAM1 phosphoglycerate mutase 1
MED13L mediator complex subunit 13L
RCAN2 regulator of calcineurin 2
MAP2K2 mitogen-activated protein kinase kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
RC3H2 ring finger and CCCH-type domains 2
TBC1D4 TBC1 domain family member 4
GPATCH8 G-patch domain containing 8
SCN1B sodium voltage-gated channel beta subunit 1
PURB purine rich element binding protein B
PFKP phosphofructokinase, platelet


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