KEGG 05230 Central carbon metabolism in cancer
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa05230 Central carbon metabolism in cancer 24
hsa04066 HIF-1 signaling pathway 16
hsa00010 Glycolysis / Gluconeogenesis 14
hsa01200 Carbon metabolism 12
hsa04151 PI3K-Akt signaling pathway 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu05230 Central carbon metabolism in cancer 26
mmu04066 HIF-1 signaling pathway 18
mmu00010 Glycolysis / Gluconeogenesis 14
mmu01200 Carbon metabolism 14
mmu05200 Pathways in cancer 12
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05230 Central carbon metabolism in cancer 18
rno04066 HIF-1 signaling pathway 14
rno00010 Glycolysis / Gluconeogenesis 11
rno04919 Thyroid hormone signaling pathway 10
rno01200 Carbon metabolism 9
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc00010 Glycolysis / Gluconeogenesis 14
mcc05230 Central carbon metabolism in cancer 14
mcc01200 Carbon metabolism 12
mcc04922 Glucagon signaling pathway 12
mcc04066 HIF-1 signaling pathway 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa05230 Central carbon metabolism in cancer 18
cfa04066 HIF-1 signaling pathway 14
cfa01200 Carbon metabolism 13
cfa00010 Glycolysis / Gluconeogenesis 11
cfa01230 Biosynthesis of amino acids 8
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca05230 Central carbon metabolism in cancer 25
fca04066 HIF-1 signaling pathway 17
fca00010 Glycolysis / Gluconeogenesis 15
fca01200 Carbon metabolism 15
fca01230 Biosynthesis of amino acids 13
Gene list in the network
Symbol Function*
AK4 adenylate kinase 4
AKT2 AKT serine/threonine kinase 2
ATP5F1A ATP synthase F1 subunit alpha
ATP5F1B ATP synthase F1 subunit beta
COL6A3 collagen type VI alpha 3 chain
ENO1 enolase 1
FGFR3 fibroblast growth factor receptor 3
FGFR2 fibroblast growth factor receptor 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GPI glucose-6-phosphate isomerase
HDC histidine decarboxylase
HK1 hexokinase 1
HK2 hexokinase 2
KIT KIT proto-oncogene, receptor tyrosine kinase
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1
NTRK1 neurotrophic receptor tyrosine kinase 1
PDGFRA platelet derived growth factor receptor alpha
PDGFRB platelet derived growth factor receptor beta
PDHA1 pyruvate dehydrogenase E1 subunit alpha 1
PDHB pyruvate dehydrogenase E1 subunit beta
PDK1 pyruvate dehydrogenase kinase 1
PDK3 pyruvate dehydrogenase kinase 3
PFKM phosphofructokinase, muscle
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1
PGK1 phosphoglycerate kinase 1
PKM pyruvate kinase M1/2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
SIAH2 siah E3 ubiquitin protein ligase 2
SLC1A5 solute carrier family 1 member 5
SLC2A1 solute carrier family 2 member 1
SPAG4 sperm associated antigen 4
USF2 upstream transcription factor 2, c-fos interacting
SLC7A5 solute carrier family 7 member 5
SLC16A3 solute carrier family 16 member 3
ERO1A endoplasmic reticulum oxidoreductase 1 alpha
MIR210HG MIR210 host gene
Symbol Function*
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Aldoa aldolase A, fructose-bisphosphate
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Eno1 enolase 1, alpha non-neuron
Erbb2 erb-b2 receptor tyrosine kinase 2
Fgfr2 fibroblast growth factor receptor 2
Fgfr3 fibroblast growth factor receptor 3
G6pdx glucose-6-phosphate dehydrogenase X-linked
Gpi1 glucose-6-phosphate isomerase 1
Hk1 hexokinase 1
Hk2 hexokinase 2
Hras Harvey rat sarcoma virus oncogene
Ldha lactate dehydrogenase A
Mbd3 methyl-CpG binding domain protein 3
Pdgfra platelet derived growth factor receptor, alpha polypeptide
Pdgfrb platelet derived growth factor receptor, beta polypeptide
Pdha1 pyruvate dehydrogenase E1 alpha 1
Pfkl phosphofructokinase, liver, B-type
Pgam1 phosphoglycerate mutase 1
Pgk1 phosphoglycerate kinase 1
Pkm pyruvate kinase, muscle
Ptpn13 protein tyrosine phosphatase, non-receptor type 13
Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5
Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Stxbp1 syntaxin binding protein 1
Tpi1 triosephosphate isomerase 1
Akt3 thymoma viral proto-oncogene 3
Map2k1 mitogen-activated protein kinase kinase 1
Map2k2 mitogen-activated protein kinase kinase 2
Pfkp phosphofructokinase, platelet
Mtch1 mitochondrial carrier 1
Pdhb pyruvate dehydrogenase (lipoamide) beta
Slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3
Csnk1g2 casein kinase 1, gamma 2
Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1
Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1
Symbol Function*
Eno1 enolase 1
Ldha lactate dehydrogenase A
Ldhb lactate dehydrogenase B
Nras NRAS proto-oncogene, GTPase
Pdgfrb platelet derived growth factor receptor beta
Pgam1 phosphoglycerate mutase 1
Pgk1 phosphoglycerate kinase 1
Slc2a1 solute carrier family 2 member 1
Tpi1 triosephosphate isomerase 1
Hk1 hexokinase 1
Hk2 hexokinase 2
Pdgfra platelet derived growth factor receptor alpha
Pfkl phosphofructokinase, liver type
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Stk39 serine threonine kinase 39
Mtor mechanistic target of rapamycin kinase
Map2k2 mitogen activated protein kinase kinase 2
Pfkp phosphofructokinase, platelet
Pi4ka phosphatidylinositol 4-kinase alpha
Pfkm phosphofructokinase, muscle
Mtpn myotrophin
Slc16a3 solute carrier family 16 member 3
Mapk1 mitogen activated protein kinase 1
Map2k1 mitogen activated protein kinase kinase 1
Ero1a endoplasmic reticulum oxidoreductase 1 alpha
Hras HRas proto-oncogene, GTPase
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Tln2 talin 2
Symbol Function*
PDHB pyruvate dehydrogenase E1 subunit beta
GAPDH glyceraldehyde-3-phosphate dehydrogenase
LDHC lactate dehydrogenase C
LDHA lactate dehydrogenase A
SLC7A5 solute carrier family 7 member 5
LOC696959 phosphoglycerate mutase 1
PKM pyruvate kinase M1/2
UQCRC2 ubiquinol-cytochrome c reductase core protein II
SLC2A1 solute carrier family 2 member 1
COQ9 coenzyme Q9
YPEL4 yippee like 4
PGAM1 phosphoglycerate mutase 1
PFKM phosphofructokinase, muscle
RABL6 RAB, member RAS oncogene family like 6
ENO1 enolase 1
LOC710798 pyruvate kinase PKM
TPI1 triosephosphate isomerase 1
MAP2K2 mitogen-activated protein kinase kinase 2
PFKL phosphofructokinase, liver type
PFKP phosphofructokinase, platelet
PDHA1 pyruvate dehydrogenase E1 subunit alpha 1
Symbol Function*
VEGFA vascular endothelial growth factor A
PKM pyruvate kinase M1/2
ANKRD37 ankyrin repeat domain 37
PDHB pyruvate dehydrogenase E1 subunit beta
PDK1 pyruvate dehydrogenase kinase 1
LDHA lactate dehydrogenase A
PGAM1 phosphoglycerate mutase 1
PFKP phosphofructokinase, platelet
FAM162A family with sequence similarity 162 member A
IDH1 isocitrate dehydrogenase (NADP(+)) 1
IDH2 isocitrate dehydrogenase (NADP(+)) 2
HK1 hexokinase 1
ENO1 enolase 1
ENOSF1 enolase superfamily member 1
PGK1 phosphoglycerate kinase 1
SLC2A1 solute carrier family 2 member 1
SLC16A3 solute carrier family 16 member 3
ACAT2 acetyl-CoA acetyltransferase 2
SLC1A5 solute carrier family 1 member 5
FKBP8 FKBP prolyl isomerase 8
TRIB3 tribbles pseudokinase 3
PFKL phosphofructokinase, liver type
SLC7A5 solute carrier family 7 member 5
MAPKAPK2 MAPK activated protein kinase 2
AKT1 AKT serine/threonine kinase 1
BNIP3 BCL2 interacting protein 3
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
MAP2K2 mitogen-activated protein kinase kinase 2
GPI glucose-6-phosphate isomerase
HK2 hexokinase 2
Symbol Function*
MET MET proto-oncogene, receptor tyrosine kinase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
CS citrate synthase
SLC2A1 solute carrier family 2 member 1
MYC MYC proto-oncogene, bHLH transcription factor
EGFR epidermal growth factor receptor
GLS glutaminase
LOC101081229 pyruvate kinase PKM
MAP2K1 mitogen-activated protein kinase kinase 1
LRRC38 leucine rich repeat containing 38
PITPNM1 phosphatidylinositol transfer protein membrane associated 1
IDH2 isocitrate dehydrogenase (NADP(+)) 2
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
PDGFRB platelet derived growth factor receptor beta
TPI1 triosephosphate isomerase 1
PGK1 phosphoglycerate kinase 1
MAPK1 mitogen-activated protein kinase 1
PFKM phosphofructokinase, muscle
SLC1A5 solute carrier family 1 member 5
PDGFRA platelet derived growth factor receptor alpha
PFKL phosphofructokinase, liver type
LDHB lactate dehydrogenase B
PDK1 pyruvate dehydrogenase kinase 1
ENO1 enolase 1
PGAM2 phosphoglycerate mutase 2
LOC101097072 ATP-dependent 6-phosphofructokinase, platelet type
MTOR mechanistic target of rapamycin kinase
MTMR1 myotubularin related protein 1
HK1 hexokinase 1
PGAM1 phosphoglycerate mutase 1
LDHA lactate dehydrogenase A
PDHB pyruvate dehydrogenase E1 subunit beta
RET ret proto-oncogene
ATP5F1A ATP synthase F1 subunit alpha
LOC102902292 uncharacterized LOC102902292
PFKP phosphofructokinase, platelet


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