[←][→] hsa  MAPK7 Gene
functional annotation
Function   mitogen-activated protein kinase 7  
GO BP
GO:0051344 [list] [network] negative regulation of cyclic-nucleotide phosphodiesterase activity  (6 genes)  NAS  
GO:0071499 [list] [network] cellular response to laminar fluid shear stress  (8 genes)  IMP TAS  
GO:0034115 [list] [network] negative regulation of heterotypic cell-cell adhesion  (11 genes)  IGI  
GO:0070885 [list] [network] negative regulation of calcineurin-NFAT signaling cascade  (15 genes)  IEA  
GO:1902176 [list] [network] negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway  (20 genes)  IMP  
GO:0036003 [list] [network] positive regulation of transcription from RNA polymerase II promoter in response to stress  (24 genes)  IMP  
GO:0019933 [list] [network] cAMP-mediated signaling  (32 genes)  NAS  
GO:2001240 [list] [network] negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (33 genes)  IGI  
GO:2000352 [list] [network] negative regulation of endothelial cell apoptotic process  (36 genes)  IMP  
GO:0070301 [list] [network] cellular response to hydrogen peroxide  (75 genes)  IMP  
GO:0060761 [list] [network] negative regulation of response to cytokine stimulus  (86 genes)  IGI  
GO:0071560 [list] [network] cellular response to transforming growth factor beta stimulus  (161 genes)  IDA  
GO:0018105 [list] [network] peptidyl-serine phosphorylation  (184 genes)  IEA  
GO:0007411 [list] [network] axon guidance  (270 genes)  TAS  
GO:0045765 [list] [network] regulation of angiogenesis  (346 genes)  IEA  
GO:0050728 [list] [network] negative regulation of inflammatory response  (352 genes)  TAS  
GO:0000165 [list] [network] MAPK cascade  (376 genes)  IEA  
GO:0071363 [list] [network] cellular response to growth factor stimulus  (508 genes)  IGI  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (1184 genes)  IGI  
GO:0007049 [list] [network] cell cycle  (1340 genes)  IEA  
GO:0051247 [list] [network] positive regulation of protein metabolic process  (1471 genes)  IGI  
GO:0035556 [list] [network] intracellular signal transduction  (1640 genes)  IBA  
GO:0007165 [list] [network] signal transduction  (5169 genes)  TAS  
GO CC
GO:0016605 [list] [network] PML body  (104 genes)  IDA  
GO:0005654 [list] [network] nucleoplasm  (4086 genes)  IDA TAS  
GO:0005829 [list] [network] cytosol  (5345 genes)  IDA TAS  
GO:0005634 [list] [network] nucleus  (8115 genes)  IBA IDA  
GO:0005737 [list] [network] cytoplasm  (11897 genes)  IBA IDA  
GO MF
GO:0004707 [list] [network] MAP kinase activity  (14 genes)  IBA  
GO:0051019 [list] [network] mitogen-activated protein kinase binding  (34 genes)  IPI  
GO:0106310 [list] [network] protein serine kinase activity  (360 genes)  IEA  
GO:0106311 [list] [network] protein threonine kinase activity  (360 genes)  IEA  
GO:0004674 [list] [network] protein serine/threonine kinase activity  (433 genes)  IBA  
GO:0005524 [list] [network] ATP binding  (1474 genes)  IEA  
GO:0005515 [list] [network] protein binding  (13898 genes)  IPI  
KEGG hsa04010 [list] [network] MAPK signaling pathway (294 genes)
hsa04540 [list] [network] Gap junction (88 genes)
hsa04657 [list] [network] IL-17 signaling pathway (94 genes)
hsa04722 [list] [network] Neurotrophin signaling pathway (119 genes)
hsa04912 [list] [network] GnRH signaling pathway (93 genes)
hsa04921 [list] [network] Oxytocin signaling pathway (154 genes)
hsa05206 [list] [network] MicroRNAs in cancer (310 genes)
hsa05418 [list] [network] Fluid shear stress and atherosclerosis (139 genes)
Protein NP_002740.2  NP_620601.1  NP_620602.2  NP_620603.2  XP_006721620.1  XP_006721621.1  XP_006721622.1  XP_011522259.1 
BLAST NP_002740.2  NP_620601.1  NP_620602.2  NP_620603.2  XP_006721620.1  XP_006721621.1  XP_006721622.1  XP_011522259.1 
Orthologous [Ortholog page] MAPK1 (hsa)  MAPK3 (hsa)  Mapk7 (mmu)  Mapk1 (mmu)  Mapk3 (mmu)  Erk7 (dme)  Mapk3 (rno)  Mapk7 (rno)  Mapk1 (rno)  mpk-2 (cel)  mpk-1 (cel)  mapk-15 (cel)  pmk-3 (cel)  sma-5 (cel)  MAPK15 (hsa)  Mapk15 (rno)  Mapk15 (mmu)  F09C12.2 (cel)  mapk1 (dre)  MAPK3 (gga)  mapk3 (dre)  MAPK15 (gga)  MAPK1 (cfa)  MAPK15 (cfa)  MAPK7 (cfa)  mapk7 (dre)  mapk15 (dre)  MAPK1 (mcc)  MAPK7 (mcc)  MAPK3 (mcc)  FUS3 (sce)  KSS1 (sce)  KDX1 (sce)  SMK1 (sce)  SLT2 (sce)  p38c (dme)  rl (dme)  MAPK15 (mcc)  MAPK3 (cfa)  MAPK1 (fca)  MAPK3 (fca)  MAPK15 (fca)  MAPK7 (fca) 
Subcellular
localization
wolf
nucl 8,  cyto_nucl 6,  cyto 3  (predict for NP_002740.2)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for NP_620601.1)
nucl 8,  cyto_nucl 6,  cyto 3  (predict for NP_620602.2)
nucl 8,  cyto_nucl 6,  cyto 3  (predict for NP_620603.2)
nucl 7,  cyto_nucl 6,  cyto 3  (predict for XP_006721620.1)
nucl 7,  cyto_nucl 6,  cyto 3  (predict for XP_006721621.1)
nucl 7,  cyto_nucl 6,  cyto 3  (predict for XP_006721622.1)
nucl 8,  cyto_nucl 5,  cyto 2  (predict for XP_011522259.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
Genes directly connected with MAPK7 on the network
coex z* Locus Function* Coexpression
detail		 CoexPub Entrez Gene ID*
6.1 MNT MAX network transcriptional repressor [detail] 0 4335
5.8 BICRA BRD4 interacting chromatin remodeling complex associated protein [detail] 0 29998
5.6 FBXL12 F-box and leucine rich repeat protein 12 [detail] 0 54850
4.5 EPN2 epsin 2 [detail] 0 22905
Coexpressed
gene list		 [Coexpressed gene list for MAPK7]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity* tissue specificity
Link to other DBs
Entrez Gene ID 5598      
Refseq ID (protein) NP_002740.2 
NP_620601.1 
NP_620602.2 
NP_620603.2 
XP_006721620.1 
XP_006721621.1 
XP_006721622.1 
XP_011522259.1 


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