| Representative coexpressed gene network |

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| hsa04722 |
Neurotrophin signaling pathway |
41 |
 |
| hsa04015 |
Rap1 signaling pathway |
26 |
 |
| hsa05163 |
Human cytomegalovirus infection |
26 |
 |
| hsa05200 |
Pathways in cancer |
25 |
 |
| hsa05170 |
Human immunodeficiency virus 1 infection |
25 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| mmu04722 |
Neurotrophin signaling pathway |
51 |
 |
| mmu04010 |
MAPK signaling pathway |
33 |
 |
| mmu05200 |
Pathways in cancer |
33 |
 |
| mmu05417 |
Lipid and atherosclerosis |
31 |
 |
| mmu04014 |
Ras signaling pathway |
30 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| rno04722 |
Neurotrophin signaling pathway |
44 |
 |
| rno04010 |
MAPK signaling pathway |
30 |
 |
| rno05200 |
Pathways in cancer |
27 |
 |
| rno04014 |
Ras signaling pathway |
25 |
 |
| rno05163 |
Human cytomegalovirus infection |
23 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| mcc04722 |
Neurotrophin signaling pathway |
43 |
 |
| mcc05200 |
Pathways in cancer |
30 |
 |
| mcc04010 |
MAPK signaling pathway |
29 |
 |
| mcc05417 |
Lipid and atherosclerosis |
28 |
 |
| mcc05170 |
Human immunodeficiency virus 1 infection |
27 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| cfa04722 |
Neurotrophin signaling pathway |
43 |
 |
| cfa05200 |
Pathways in cancer |
26 |
 |
| cfa04910 |
Insulin signaling pathway |
23 |
 |
| cfa05163 |
Human cytomegalovirus infection |
21 |
 |
| cfa05170 |
Human immunodeficiency virus 1 infection |
21 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| fca04722 |
Neurotrophin signaling pathway |
48 |
 |
| fca05200 |
Pathways in cancer |
28 |
 |
| fca05417 |
Lipid and atherosclerosis |
26 |
 |
| fca05170 |
Human immunodeficiency virus 1 infection |
25 |
 |
| fca04010 |
MAPK signaling pathway |
24 |
 |
|
| Gene list in the network |
|
Symbol |
Function* |
| |
ABL1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
| |
AKT2 |
AKT serine/threonine kinase 2 |
| |
FASLG |
Fas ligand |
| |
RHOA |
ras homolog family member A |
| |
CALM1 |
calmodulin 1 |
| |
CALM2 |
calmodulin 2 |
| |
CALM3 |
calmodulin 3 |
| |
CALML3 |
calmodulin like 3 |
| |
CRKL |
CRK like proto-oncogene, adaptor protein |
| |
MAPK14 |
mitogen-activated protein kinase 14 |
| |
GNAI3 |
G protein subunit alpha i3 |
| |
RAPGEF1 |
Rap guanine nucleotide exchange factor 1 |
| |
IRAK2 |
interleukin 1 receptor associated kinase 2 |
| |
ITPR3 |
inositol 1,4,5-trisphosphate receptor type 3 |
| |
KRAS |
KRAS proto-oncogene, GTPase |
| |
MATK |
megakaryocyte-associated tyrosine kinase |
| |
MAP3K3 |
mitogen-activated protein kinase kinase kinase 3 |
| |
NFKB1 |
nuclear factor kappa B subunit 1 |
| |
NFKB2 |
nuclear factor kappa B subunit 2 |
| |
NFKBIA |
NFKB inhibitor alpha |
| |
NFKBIB |
NFKB inhibitor beta |
| |
NFKBIE |
NFKB inhibitor epsilon |
| |
NGF |
nerve growth factor |
| |
NRAS |
NRAS proto-oncogene, GTPase |
| |
NTF3 |
neurotrophin 3 |
| |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| |
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| |
PLCG1 |
phospholipase C gamma 1 |
| |
PRKCD |
protein kinase C delta |
| |
MAPK1 |
mitogen-activated protein kinase 1 |
| |
MAPK11 |
mitogen-activated protein kinase 11 |
| |
MAPK13 |
mitogen-activated protein kinase 13 |
| |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
| |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
| |
PTPN6 |
protein tyrosine phosphatase non-receptor type 6 |
| |
RAC1 |
Rac family small GTPase 1 |
| |
RAP1A |
RAP1A, member of RAS oncogene family |
| |
RAP1B |
RAP1B, member of RAS oncogene family |
| |
RELB |
RELB proto-oncogene, NF-kB subunit |
| |
RPS6KA1 |
ribosomal protein S6 kinase A1 |
| |
MAPK12 |
mitogen-activated protein kinase 12 |
| |
SOS2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
USF2 |
upstream transcription factor 2, c-fos interacting |
| |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| |
YWHAH |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta |
| |
RPS6KA5 |
ribosomal protein S6 kinase A5 |
| |
CD83 |
CD83 molecule |
| |
ACTR2 |
actin related protein 2 |
| |
TBC1D2B |
TBC1 domain family member 2B |
| |
ATP11B |
ATPase phospholipid transporting 11B (putative) |
| |
TBX21 |
T-box transcription factor 21 |
| |
CALML5 |
calmodulin like 5 |
| |
ALKBH5 |
alkB homolog 5, RNA demethylase |
| |
KIDINS220 |
kinase D interacting substrate 220 |
| |
TXNDC16 |
thioredoxin domain containing 16 |
| |
TRAPPC1 |
trafficking protein particle complex subunit 1 |
| |
ZC3H12A |
zinc finger CCCH-type containing 12A |
| |
PRRC2B |
proline rich coiled-coil 2B |
|
|
Symbol |
Function* |
| |
Akt1 |
thymoma viral proto-oncogene 1 |
| |
Akt2 |
thymoma viral proto-oncogene 2 |
| |
Rhoa |
ras homolog family member A |
| |
Bcl2 |
B cell leukemia/lymphoma 2 |
| |
Calm1 |
calmodulin 1 |
| |
Calm2 |
calmodulin 2 |
| |
Calm3 |
calmodulin 3 |
| |
Camk2g |
calcium/calmodulin-dependent protein kinase II gamma |
| |
Cdc42 |
cell division cycle 42 |
| |
Cfl1 |
cofilin 1, non-muscle |
| |
Crkl |
v-crk avian sarcoma virus CT10 oncogene homolog-like |
| |
Eef2k |
eukaryotic elongation factor-2 kinase |
| |
Gnai2 |
guanine nucleotide binding protein (G protein), alpha inhibiting 2 |
| |
Gnb1 |
guanine nucleotide binding protein (G protein), beta 1 |
| |
Grb2 |
growth factor receptor bound protein 2 |
| |
Hras |
Harvey rat sarcoma virus oncogene |
| |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
| |
Kras |
Kirsten rat sarcoma viral oncogene homolog |
| |
Sh2b3 |
SH2B adaptor protein 3 |
| |
Mbd3 |
methyl-CpG binding domain protein 3 |
| |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
| |
Nfkb2 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 |
| |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
| |
Nfkbib |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
| |
Nfkbie |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon |
| |
Ngfr |
nerve growth factor receptor (TNFR superfamily, member 16) |
| |
Nras |
neuroblastoma ras oncogene |
| |
Ntrk1 |
neurotrophic tyrosine kinase, receptor, type 1 |
| |
Ntrk2 |
neurotrophic tyrosine kinase, receptor, type 2 |
| |
Ntrk3 |
neurotrophic tyrosine kinase, receptor, type 3 |
| |
Pdpk1 |
3-phosphoinositide dependent protein kinase 1 |
| |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
| |
Pitpna |
phosphatidylinositol transfer protein, alpha |
| |
Ppp3r1 |
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) |
| |
Mapk11 |
mitogen-activated protein kinase 11 |
| |
Prkx |
protein kinase, X-linked |
| |
Ptpn12 |
protein tyrosine phosphatase, non-receptor type 12 |
| |
Rac1 |
Rac family small GTPase 1 |
| |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
| |
Relb |
avian reticuloendotheliosis viral (v-rel) oncogene related B |
| |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
| |
Sos2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
Tnfaip3 |
tumor necrosis factor, alpha-induced protein 3 |
| |
Traf6 |
TNF receptor-associated factor 6 |
| |
Ywhae |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide |
| |
Ywhah |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide |
| |
Ywhaz |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
| |
Map2k5 |
mitogen-activated protein kinase kinase 5 |
| |
Map2k2 |
mitogen-activated protein kinase kinase 2 |
| |
Map3k3 |
mitogen-activated protein kinase kinase kinase 3 |
| |
Mapk1 |
mitogen-activated protein kinase 1 |
| |
Mapk14 |
mitogen-activated protein kinase 14 |
| |
Mapk3 |
mitogen-activated protein kinase 3 |
| |
Mapk12 |
mitogen-activated protein kinase 12 |
| |
Mtch1 |
mitochondrial carrier 1 |
| |
Foxo3 |
forkhead box O3 |
| |
Jmy |
junction-mediating and regulatory protein |
| |
Ccny |
cyclin Y |
| |
Calml3 |
calmodulin-like 3 |
| |
Irak3 |
interleukin-1 receptor-associated kinase 3 |
| |
Actr3 |
ARP3 actin-related protein 3 |
| |
Dcp1a |
decapping mRNA 1A |
| |
Rab1b |
RAB1B, member RAS oncogene family |
| |
Calm4 |
calmodulin 4 |
| |
Csnk1g2 |
casein kinase 1, gamma 2 |
| |
Pip4k2b |
phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| |
Rap1a |
RAS-related protein 1a |
| |
Rps6ka3 |
ribosomal protein S6 kinase polypeptide 3 |
| |
Rasa2 |
RAS p21 protein activator 2 |
| |
Hdac10 |
histone deacetylase 10 |
| |
Ripk2 |
receptor (TNFRSF)-interacting serine-threonine kinase 2 |
| |
Arhgdia |
Rho GDP dissociation inhibitor (GDI) alpha |
| |
Rap1b |
RAS related protein 1b |
| |
Gm94 |
predicted gene 94 |
| |
Zc3h12a |
zinc finger CCCH type containing 12A |
| |
Frs2 |
fibroblast growth factor receptor substrate 2 |
| |
Ep300 |
E1A binding protein p300 |
|
|
Symbol |
Function* |
| |
Calm1 |
calmodulin 1 |
| |
Calm3 |
calmodulin 3 |
| |
Kras |
KRAS proto-oncogene, GTPase |
| |
Ngfr |
nerve growth factor receptor |
| |
Nras |
NRAS proto-oncogene, GTPase |
| |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
| |
Camk2a |
calcium/calmodulin-dependent protein kinase II alpha |
| |
Plcg1 |
phospholipase C, gamma 1 |
| |
Map2k5 |
mitogen activated protein kinase kinase 5 |
| |
Ntrk3 |
neurotrophic receptor tyrosine kinase 3 |
| |
Ppp3r1 |
protein phosphatase 3, regulatory subunit B, alpha |
| |
Ywhae |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| |
Mapk9 |
mitogen-activated protein kinase 9 |
| |
Calm2 |
calmodulin 2 |
| |
Mapk3 |
mitogen activated protein kinase 3 |
| |
Cr1l |
complement C3b/C4b receptor 1 like |
| |
Crk |
CRK proto-oncogene, adaptor protein |
| |
Sh2b3 |
SH2B adaptor protein 3 |
| |
Map2k2 |
mitogen activated protein kinase kinase 2 |
| |
Slc30a1 |
solute carrier family 30 member 1 |
| |
Ntrk1 |
neurotrophic receptor tyrosine kinase 1 |
| |
Mapk12 |
mitogen-activated protein kinase 12 |
| |
Matk |
megakaryocyte-associated tyrosine kinase |
| |
Cdc42 |
cell division cycle 42 |
| |
Rab2a |
RAB2A, member RAS oncogene family |
| |
Agap2 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| |
Mtpn |
myotrophin |
| |
Grb2 |
growth factor receptor bound protein 2 |
| |
Gnb2 |
G protein subunit beta 2 |
| |
Nfkb1 |
nuclear factor kappa B subunit 1 |
| |
Pdpk1 |
3-phosphoinositide dependent protein kinase-1 |
| |
Gsk3b |
glycogen synthase kinase 3 beta |
| |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
| |
Sos2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
Shc1 |
SHC adaptor protein 1 |
| |
Pip4k2b |
phosphatidylinositol-5-phosphate 4-kinase type 2 beta |
| |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
| |
Mapk7 |
mitogen-activated protein kinase 7 |
| |
Mapk1 |
mitogen activated protein kinase 1 |
| |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
| |
Prkcd |
protein kinase C, delta |
| |
Map2k1 |
mitogen activated protein kinase kinase 1 |
| |
Ipmk |
inositol polyphosphate multikinase |
| |
Mapkapk2 |
MAPK activated protein kinase 2 |
| |
Actr2 |
actin related protein 2 |
| |
Hras |
HRas proto-oncogene, GTPase |
| |
Abhd17a |
abhydrolase domain containing 17A, depalmitoylase |
| |
Fbxo11 |
F-box protein 11 |
| |
Map3k3 |
mitogen activated protein kinase kinase kinase 3 |
| |
Dtx2 |
deltex E3 ubiquitin ligase 2 |
| |
Rela |
RELA proto-oncogene, NF-kB subunit |
| |
Nfkb2 |
nuclear factor kappa B subunit 2 |
| |
Mlf2 |
myeloid leukemia factor 2 |
| |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
| |
Nfkbie |
NFKB inhibitor epsilon |
| |
Gtf2i |
general transcription factor II I |
| |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
| |
Vasp |
vasodilator-stimulated phosphoprotein |
| |
Irak2 |
interleukin-1 receptor-associated kinase 2 |
| |
Ripk2 |
receptor-interacting serine-threonine kinase 2 |
| |
Tnip1 |
TNFAIP3 interacting protein 1 |
| |
Rac1 |
Rac family small GTPase 1 |
| |
Mapk11 |
mitogen-activated protein kinase 11 |
| |
Relb |
RELB proto-oncogene, NF-kB subunit |
| |
Ctdsp2 |
CTD small phosphatase 2 |
|
|
Symbol |
Function* |
| |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
| |
CAP1 |
cyclase associated actin cytoskeleton regulatory protein 1 |
| |
NPEPPS |
aminopeptidase puromycin sensitive |
| |
PRKCD |
protein kinase C delta |
| |
NFKBIB |
NFKB inhibitor beta |
| |
MAPKAPK2 |
MAPK activated protein kinase 2 |
| |
LOC695047 |
protein DDI1 homolog 2 |
| |
NFKBIA |
NFKB inhibitor alpha |
| |
ASAP1 |
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| |
CRKL |
CRK like proto-oncogene, adaptor protein |
| |
RPS6KA3 |
ribosomal protein S6 kinase A3 |
| |
STUB1 |
STIP1 homology and U-box containing protein 1 |
| |
AKT1 |
AKT serine/threonine kinase 1 |
| |
ST3GAL1 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| |
SORT1 |
sortilin 1 |
| |
CALM1 |
calmodulin 1 |
| |
MAPK1 |
mitogen-activated protein kinase 1 |
| |
HRAS |
HRas proto-oncogene, GTPase |
| |
IRAK1 |
interleukin 1 receptor associated kinase 1 |
| |
AKT2 |
AKT serine/threonine kinase 2 |
| |
STXBP5 |
syntaxin binding protein 5 |
| |
GRB2 |
growth factor receptor bound protein 2 |
| |
NFKBIE |
NFKB inhibitor epsilon |
| |
CAMK2D |
calcium/calmodulin dependent protein kinase II delta |
| |
PCBP2 |
poly(rC) binding protein 2 |
| |
GNAI2 |
G protein subunit alpha i2 |
| |
B4GALT2 |
beta-1,4-galactosyltransferase 2 |
| |
SOS2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
CAPZA1 |
capping actin protein of muscle Z-line subunit alpha 1 |
| |
CAMK2G |
calcium/calmodulin dependent protein kinase II gamma |
| |
RHOA |
ras homolog family member A |
| |
TAB3 |
TGF-beta activated kinase 1 (MAP3K7) binding protein 3 |
| |
MAPK3 |
mitogen-activated protein kinase 3 |
| |
NRAS |
NRAS proto-oncogene, GTPase |
| |
PCBP1 |
poly(rC) binding protein 1 |
| |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
| |
PPP3CA |
protein phosphatase 3 catalytic subunit alpha |
| |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| |
NFKB1 |
nuclear factor kappa B subunit 1 |
| |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
| |
SH2B3 |
SH2B adaptor protein 3 |
| |
MAPK8 |
mitogen-activated protein kinase 8 |
| |
MAP3K5 |
mitogen-activated protein kinase kinase kinase 5 |
| |
GSK3B |
glycogen synthase kinase 3 beta |
| |
AGO4 |
argonaute RISC component 4 |
| |
SOS1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
| |
RELB |
RELB proto-oncogene, NF-kB subunit |
| |
LOC714689 |
nuclear factor NF-kappa-B p100 subunit |
| |
ARHGDIA |
Rho GDP dissociation inhibitor alpha |
| |
MAPK12 |
mitogen-activated protein kinase 12 |
| |
MAPK9 |
mitogen-activated protein kinase 9 |
| |
MAPK11 |
mitogen-activated protein kinase 11 |
| |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
| |
CALM3 |
calmodulin 3 |
| |
RPS6KA2 |
ribosomal protein S6 kinase A2 |
| |
KIAA2026 |
KIAA2026 |
| |
BAD |
BCL2 associated agonist of cell death |
| |
RAC1 |
Rac family small GTPase 1 |
| |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
| |
MAP3K3 |
mitogen-activated protein kinase kinase kinase 3 |
| |
RAP1B |
RAP1B, member of RAS oncogene family |
| |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
| |
BAX |
BCL2 associated X, apoptosis regulator |
| |
PIK3R2 |
phosphoinositide-3-kinase regulatory subunit 2 |
| |
AP1S1 |
adaptor related protein complex 1 subunit sigma 1 |
| |
CFL1 |
cofilin 1 |
| |
CHPF2 |
chondroitin polymerizing factor 2 |
|
|
|