KEGG 04150 mTOR signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) dme(Fly) cel(Nematoda) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04150 mTOR signaling pathway 47
hsa05165 Human papillomavirus infection 26
hsa05200 Pathways in cancer 20
hsa05224 Breast cancer 19
hsa05225 Hepatocellular carcinoma 19
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04150 mTOR signaling pathway 68
mmu05165 Human papillomavirus infection 41
mmu05010 Alzheimer disease 30
mmu05200 Pathways in cancer 29
mmu05225 Hepatocellular carcinoma 29
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04150 mTOR signaling pathway 68
rno05165 Human papillomavirus infection 37
rno05200 Pathways in cancer 28
rno05010 Alzheimer disease 28
rno05205 Proteoglycans in cancer 27
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04150 mTOR signaling pathway 64
gga04916 Melanogenesis 23
gga04310 Wnt signaling pathway 19
gga04140 Autophagy - animal 18
gga04910 Insulin signaling pathway 18
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04150 mTOR signaling pathway 74
dre04310 Wnt signaling pathway 20
dre04916 Melanogenesis 20
dre04140 Autophagy - animal 20
dre04068 FoxO signaling pathway 18
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dme04150 mTOR signaling pathway 43
dme04140 Autophagy - animal 16
dme04068 FoxO signaling pathway 11
dme04213 Longevity regulating pathway - multiple species 10
dme00190 Oxidative phosphorylation 10
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel04150 mTOR signaling pathway 41
cel04145 Phagosome 14
cel00190 Oxidative phosphorylation 13
cel04140 Autophagy - animal 13
cel04068 FoxO signaling pathway 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04150 mTOR signaling pathway 64
mcc05165 Human papillomavirus infection 34
mcc05200 Pathways in cancer 31
mcc05224 Breast cancer 27
mcc05225 Hepatocellular carcinoma 27
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04150 mTOR signaling pathway 50
cfa05165 Human papillomavirus infection 25
cfa05200 Pathways in cancer 17
cfa05205 Proteoglycans in cancer 17
cfa04151 PI3K-Akt signaling pathway 16
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04150 mTOR signaling pathway 44
fca05165 Human papillomavirus infection 26
fca05010 Alzheimer disease 19
fca05200 Pathways in cancer 18
fca05224 Breast cancer 18
Gene list in the network
Symbol Function*
AKT2 AKT serine/threonine kinase 2
ATP6V1A ATPase H+ transporting V1 subunit A
ATP6V1B2 ATPase H+ transporting V1 subunit B2
ATP6V1C1 ATPase H+ transporting V1 subunit C1
ATP6V1E1 ATPase H+ transporting V1 subunit E1
CARS1 cysteinyl-tRNA synthetase 1
CDC34 cell division cycle 34, ubiqiutin conjugating enzyme
DVL2 dishevelled segment polarity protein 2
GRB10 growth factor receptor bound protein 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1
MAPK3 mitogen-activated protein kinase 3
MAP2K2 mitogen-activated protein kinase kinase 2
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RPS6KA1 ribosomal protein S6 kinase A1
RPS6KA2 ribosomal protein S6 kinase A2
SEC13 SEC13 homolog, nuclear pore and COPII coat complex component
SKP2 S-phase kinase associated protein 2
SLC3A2 solute carrier family 3 member 2
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
STK11 serine/threonine kinase 11
USF2 upstream transcription factor 2, c-fos interacting
WNT3 Wnt family member 3
WNT5A Wnt family member 5A
WNT6 Wnt family member 6
WNT7B Wnt family member 7B
WNT11 Wnt family member 11
WNT9A Wnt family member 9A
NPRL3 NPR3 like, GATOR1 complex subunit
SLC7A5 solute carrier family 7 member 5
FZD4 frizzled class receptor 4
FZD9 frizzled class receptor 9
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
NTN1 netrin 1
ATP6V1G1 ATPase H+ transporting V1 subunit G1
NUP155 nucleoporin 155
TTI1 TELO2 interacting protein 1
TELO2 telomere maintenance 2
CARM1 coactivator associated arginine methyltransferase 1
ATP11B ATPase phospholipid transporting 11B (putative)
MKRN2 makorin ring finger protein 2
ATP6V1D ATPase H+ transporting V1 subunit D
CHMP5 charged multivesicular body protein 5
ATP6V1H ATPase H+ transporting V1 subunit H
DDIT4 DNA damage inducible transcript 4
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
PLEKHB2 pleckstrin homology domain containing B2
ARL8B ADP ribosylation factor like GTPase 8B
RRAGC Ras related GTP binding C
MLST8 MTOR associated protein, LST8 homolog
WNT10A Wnt family member 10A
WNT5B Wnt family member 5B
RAB1B RAB1B, member RAS oncogene family
SESN2 sestrin 2
FNIP1 folliculin interacting protein 1
RPUSD1 RNA pseudouridine synthase domain containing 1
NOTUM notum, palmitoleoyl-protein carboxylesterase
FLCN folliculin
RNF152 ring finger protein 152
Symbol Function*
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A
Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2
Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1
Atp6v1e1 ATPase, H+ transporting, lysosomal V1 subunit E1
Cab39 calcium binding protein 39
Rb1cc1 RB1-inducible coiled-coil 1
Coro1a coronin, actin binding protein 1A
Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1
Foxi1 forkhead box I1
Lpin1 lipin 1
Fzd1 frizzled class receptor 1
Fzd3 frizzled class receptor 3
Fzd7 frizzled class receptor 7
Fzd8 frizzled class receptor 8
Fzd9 frizzled class receptor 9
Gas1 growth arrest specific 1
Hras Harvey rat sarcoma virus oncogene
Ins1 insulin I
Ins2 insulin II
Insr insulin receptor
Irs1 insulin receptor substrate 1
Nprl3 nitrogen permease regulator-like 3
Mbd3 methyl-CpG binding domain protein 3
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Msx2 msh homeobox 2
Nras neuroblastoma ras oncogene
Nsf N-ethylmaleimide sensitive fusion protein
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Prkca protein kinase C, alpha
Prkcb protein kinase C, beta
Prkx protein kinase, X-linked
Pten phosphatase and tensin homolog
Atxn1 ataxin 1
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Stk11 serine/threonine kinase 11
Try4 trypsin 4
Wnt10a wingless-type MMTV integration site family, member 10A
Wnt10b wingless-type MMTV integration site family, member 10B
Wnt4 wingless-type MMTV integration site family, member 4
Wnt5a wingless-type MMTV integration site family, member 5A
Wnt5b wingless-type MMTV integration site family, member 5B
Wnt6 wingless-type MMTV integration site family, member 6
Wnt7a wingless-type MMTV integration site family, member 7A
Wnt7b wingless-type MMTV integration site family, member 7B
Map2k2 mitogen-activated protein kinase kinase 2
Ror2 receptor tyrosine kinase-like orphan receptor 2
Vps26a VPS26 retromer complex component A
Rragc Ras-related GTP binding C
Clip1 CAP-GLY domain containing linker protein 1
Vps29 VPS29 retromer complex component
Mtch1 mitochondrial carrier 1
Gsk3b glycogen synthase kinase 3 beta
Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Fzd2 frizzled class receptor 2
Nudt11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
Trappc2l trafficking protein particle complex 2-like
Tsc1 TSC complex subunit 1
Atp6v1f ATPase, H+ transporting, lysosomal V1 subunit F
Atp6v1g1 ATPase, H+ transporting, lysosomal V1 subunit G1
Atp6v1c1 ATPase, H+ transporting, lysosomal V1 subunit C1
Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Rps6ka6 ribosomal protein S6 kinase polypeptide 6
Arl8b ADP-ribosylation factor-like 8B
Akt1s1 AKT1 substrate 1 (proline-rich)
Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Atp6v1c2 ATPase, H+ transporting, lysosomal V1 subunit C2
Chac1 ChaC, cation transport regulator 1
Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2
Arrdc2 arrestin domain containing 2
Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1
Strada STE20-related kinase adaptor alpha
Fbxl20 F-box and leucine-rich repeat protein 20
Pcdh18 protocadherin 18
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D
Ddit4 DNA-damage-inducible transcript 4
Gns glucosamine (N-acetyl)-6-sulfatase
Rictor RPTOR independent companion of MTOR, complex 2
Fzd10 frizzled class receptor 10
Brk1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
Csnk1g2 casein kinase 1, gamma 2
Pdzd8 PDZ domain containing 8
Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H
Braf Braf transforming gene
Rps6ka3 ribosomal protein S6 kinase polypeptide 3
Atp6v1b1 ATPase, H+ transporting, lysosomal V1 subunit B1
Atp6v0b ATPase, H+ transporting, lysosomal V0 subunit B
Fgfrl1 fibroblast growth factor receptor-like 1
Fnip1 folliculin interacting protein 1
Wnt9a wingless-type MMTV integration site family, member 9A
Flcn folliculin
Trib3 tribbles pseudokinase 3
4932438A13Rik RIKEN cDNA 4932438A13 gene
Sesn2 sestrin 2
Ppp1r37 protein phosphatase 1, regulatory subunit 37
Slc38a9 solute carrier family 38, member 9
Nceh1 neutral cholesterol ester hydrolase 1
Tmem251 transmembrane protein 251
Fnip2 folliculin interacting protein 2
Atp6v1g3 ATPase, H+ transporting, lysosomal V1 subunit G3
Symbol Function*
Egfr epidermal growth factor receptor
Nras NRAS proto-oncogene, GTPase
Prkca protein kinase C, alpha
Tsc2 TSC complex subunit 2
Insr insulin receptor
Cstb cystatin B
Adarb1 adenosine deaminase, RNA-specific, B1
Irs1 insulin receptor substrate 1
Nfkbia NFKB inhibitor alpha
Prkg2 protein kinase cGMP-dependent 2
Asns asparagine synthetase (glutamine-hydrolyzing)
Sgk1 serum/glucocorticoid regulated kinase 1
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Slc3a2 solute carrier family 3 member 2
Slc7a5 solute carrier family 7 member 5
Mtor mechanistic target of rapamycin kinase
Map2k2 mitogen activated protein kinase kinase 2
Clip1 CAP-GLY domain containing linker protein 1
Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2
Mtpn myotrophin
Pdpk1 3-phosphoinositide dependent protein kinase-1
Tsc22d3 TSC22 domain family, member 3
Gsk3b glycogen synthase kinase 3 beta
Slc4a4 solute carrier family 4 member 4
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Braf B-Raf proto-oncogene, serine/threonine kinase
Wnt7a Wnt family member 7A
Mapk1 mitogen activated protein kinase 1
Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1
Atp6v1f ATPase H+ transporting V1 subunit F
Atp6v1b2 ATPase H+ transporting V1 subunit B2
Wnt11 Wnt family member 11
Ddit4 DNA-damage-inducible transcript 4
Map2k1 mitogen activated protein kinase kinase 1
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Foxc2 forkhead box C2
Ipmk inositol polyphosphate multikinase
Map3k2 mitogen activated protein kinase kinase kinase 2
Trib3 tribbles pseudokinase 3
Fzd3 frizzled class receptor 3
Fzd6 frizzled class receptor 6
Foxi1 forkhead box I1
Rptor regulatory associated protein of MTOR, complex 1
Atp6v1g3 ATPase H+ transporting V1 subunit G3
Nedd4l NEDD4 like E3 ubiquitin protein ligase
Dcp2 decapping mRNA 2
Rnf152 ring finger protein 152
Hras HRas proto-oncogene, GTPase
Slc35g1 solute carrier family 35, member G1
Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Mapkap1 MAPK associated protein 1
Atp6v1e1 ATPase H+ transporting V1 subunit E1
Atp6v1h ATPase H+ transporting V1 subunit H
Zbtb8os zinc finger and BTB domain containing 8 opposite strand
Rragd Ras-related GTP binding D
Atp6v1g1 ATPase H+ transporting V1 subunit G1
Rragc Ras-related GTP binding C
Atp6v1d ATPase H+ transporting V1 subunit D
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Atp6v1c1 ATPase H+ transporting V1 subunit C1
Eif4b eukaryotic translation initiation factor 4B
Cab39 calcium binding protein 39
Fbxo11 F-box protein 11
Atp6ap2 ATPase H+ transporting accessory protein 2
Flcn folliculin
Ulk2 unc-51 like autophagy activating kinase 2
Wnt9b Wnt family member 9B
Dvl3 dishevelled segment polarity protein 3
Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit
Slc38a9 solute carrier family 38, member 9
Rictor RPTOR independent companion of MTOR, complex 2
Fnip2 folliculin interacting protein 2
Atp6v1b1 ATPase H+ transporting V1 subunit B1
Rb1cc1 RB1-inducible coiled-coil 1
Focad focadhesin
Casz1 castor zinc finger 1
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Zfyve26 zinc finger FYVE-type containing 26
Pcnx1 pecanex 1
Wnt7b Wnt family member 7B
Wnt6 Wnt family member 6
Wnt10a Wnt family member 10A
Lpin2 lipin 2
Fzd5 frizzled class receptor 5
Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
Stk24 serine/threonine kinase 24
Lrrc28 leucine rich repeat containing 28
Coq10a coenzyme Q10A
Nprl2 NPR2-like, GATOR1 complex subunit
Fzd10 frizzled class receptor 10
Fzd8 frizzled class receptor 8
Lmbrd2 LMBR1 domain containing 2
Wnt16 Wnt family member 16
Stradb STE20 related adaptor beta
Sesn2 sestrin 2
Atp6v1a ATPase H+ transporting V1 subunit A
Tomm7 translocase of outer mitochondrial membrane 7
Fzd7 frizzled class receptor 7
Fnip1 folliculin interacting protein 1
Symbol Function*
FZD10 frizzled class receptor 10
MAPK3 mitogen-activated protein kinase 3
FZD8 frizzled class receptor 8
FZD2 frizzled class receptor 2
WNT7A Wnt family member 7A
CDX2 caudal type homeobox 2
WNT2B Wnt family member 2B
WNT6 Wnt family member 6
WNT3A Wnt family member 3A
ATP6V1B2 ATPase H+ transporting V1 subunit B2
WNT4 Wnt family member 4
FZD5 frizzled class receptor 5
WNT5A Wnt family member 5A
ATP6V1A ATPase H+ transporting V1 subunit A
IGF1R insulin like growth factor 1 receptor
BRAF B-Raf proto-oncogene, serine/threonine kinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
MAP2K2 mitogen-activated protein kinase kinase 2
WNT8A Wnt family member 8A
MAP2K1 mitogen-activated protein kinase kinase 1
WDR59 WD repeat domain 59
FLCN folliculin
EPN2 epsin 2
SYNGR3 synaptogyrin 3
TSC2 tuberous sclerosis 2
PRKCB protein kinase C beta
PDPK1 3-phosphoinositide dependent protein kinase 1
ATP6V0C ATPase H+ transporting V0 subunit c
TELO2 telomere maintenance 2
ULK1 unc-51 like autophagy activating kinase 1
DEPDC5 DEP domain containing 5
TSC1 tuberous sclerosis 1
ATP6V1G1 ATPase H+ transporting V1 subunit G1
PRKCA protein kinase C alpha
ULK2 unc-51 like autophagy activating kinase 2
WNT5B Wnt family member 5B
ATP6V1E1 ATPase H+ transporting V1 subunit E1
BCAT1 branched chain amino acid transaminase 1
PRR5 proline rich 5
GSK3A glycogen synthase kinase 3 alpha
RPS6KA3 ribosomal protein S6 kinase A3
EIF1AX eukaryotic translation initiation factor 1A, X-linked
TTI1 TELO2 interacting protein 1
RAB22A RAB22A, member RAS oncogene family
DVL1 dishevelled segment polarity protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
SPEN spen family transcriptional repressor
RASSF5 Ras association domain family member 5
SF3A2 splicing factor 3a subunit 2
INSR insulin receptor
ATP6V1C1 ATPase H+ transporting V1 subunit C1
DEPTOR DEP domain containing MTOR-interacting protein
LPIN2 lipin 2
BTBD9 BTB domain containing 9
AKT3 AKT serine/threonine kinase 3
ATP6V1C2 ATPase H+ transporting V1 subunit C2
LPIN1 lipin 1
UBXN2A UBX domain protein 2A
RPS6KA6 ribosomal protein S6 kinase A6
EIF4E eukaryotic translation initiation factor 4E
CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1
ATP6V1D ATPase H+ transporting V1 subunit D
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
ATP6V1G3 ATPase H+ transporting V1 subunit G3
DVL2 dishevelled segment polarity protein 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
NPRL2 NPR2-like, GATOR1 complex subunit
EIF4G3 eukaryotic translation initiation factor 4 gamma 3
SPTLC1 serine palmitoyltransferase long chain base subunit 1
ATP6V1H ATPase H+ transporting V1 subunit H
SLC38A9 solute carrier family 38 member 9
PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1
MPDZ multiple PDZ domain protein
LOC427439 Nipped-B homolog-like
RICTOR RPTOR independent companion of MTOR complex 2
WNT7B Wnt family member 7B
WNT10A Wnt family member 10A
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
PCIF1 PDX1 C-terminal inhibiting factor 1
AGO2 argonaute 2, RISC catalytic component
CRELD1 cysteine rich with EGF like domains 1
SESN2 sestrin 2
IRS2 insulin receptor substrate 2
HPS5 HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
RRAGD Ras-related GTP binding D
DDIT4 DNA damage inducible transcript 4
CBX6 chromobox 6
LOC107056274 rho-related BTB domain-containing protein 2-like
LOC112529929 keratin, type II cytoskeletal 4-like
LOC121106727 uncharacterized LOC121106727
Symbol Function*
wnt5b wingless-type MMTV integration site family, member 5b
wnt4 wingless-type MMTV integration site family, member 4
smo smoothened, frizzled class receptor
fzd4 frizzled class receptor 4
fzd10 frizzled class receptor 10
fzd7a frizzled class receptor 7a
fzd7b frizzled class receptor 7b
irx3a iroquois homeobox 3a
raf1a Raf-1 proto-oncogene, serine/threonine kinase a
gbp glycogen synthase kinase binding protein
fzd9b frizzled class receptor 9b
notch3 notch receptor 3
fzd8a frizzled class receptor 8a
atp6v1e1b ATPase H+ transporting V1 subunit E1b
atp6v0ca ATPase H+ transporting V0 subunit ca
insra insulin receptor a
insrb insulin receptor b
igf1ra insulin-like growth factor 1a receptor
igf1rb insulin-like growth factor 1b receptor
atp6v1h ATPase H+ transporting V1 subunit H
atp6v0b ATPase H+ transporting V0 subunit b
dvl2 dishevelled segment polarity protein 2
sgk1 serum/glucocorticoid regulated kinase 1
bloc1s5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
fnip1 folliculin interacting protein 1
castor2 cytosolic arginine sensor for mTORC1 subunit 2
gnsb glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
seh1l SEH1-like (S. cerevisiae)
wdr13 WD repeat domain 13
atp6v1g1 ATPase H+ transporting V1 subunit G1
tsc1a TSC complex subunit 1a
atp6v1ab ATPase H+ transporting V1 subunit Ab
atp6v1ba ATPase, H+ transporting, lysosomal, V1 subunit B, member a
atp6v1b2 ATPase H+ transporting V1 subunit B2
atp6v1c1a ATPase H+ transporting V1 subunit C1a
fkbp5 FKBP prolyl isomerase 5
ddit4 DNA-damage-inducible transcript 4
xab2 XPA binding protein 2
atp6v1d ATPase H+ transporting V1 subunit D
atp6v1aa ATPase H+ transporting V1 subunit Aa
pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
mapk3 mitogen-activated protein kinase 3
slc3a2b solute carrier family 3 member 2b
nr1d2a nuclear receptor subfamily 1, group D, member 2a
pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
fam49bb family with sequence similarity 49 member Bb
atp6ap2 ATPase H+ transporting accessory protein 2
grb2b growth factor receptor-bound protein 2b
pik3r3a phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
rhoaa ras homolog gene family, member Aa
slc25a25a solute carrier family 25 member 25a
map2k1 mitogen-activated protein kinase kinase 1
ube2v2 ubiquitin-conjugating enzyme E2 variant 2
ap3m2 adaptor related protein complex 3 subunit mu 2
atp6v1f ATPase H+ transporting V1 subunit F
ap3s2 adaptor related protein complex 3 subunit sigma 2
lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
trappc3 trafficking protein particle complex subunit 3
eloca elongin C paralog a
tspan7b tetraspanin 7b
atp6v1c1b ATPase H+ transporting V1 subunit C1b
castor1 cytosolic arginine sensor for mTORC1 subunit 1
ext1b exostosin glycosyltransferase 1b
prkcaa protein kinase C, alpha, a
rnf152 ring finger protein 152
lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
neurl4 neuralized E3 ubiquitin protein ligase 4
pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
fzd1 frizzled class receptor 1
osbpl2a oxysterol binding protein-like 2a
trioa trio Rho guanine nucleotide exchange factor a
rc3h1b ring finger and CCCH-type domains 1b
sgk2b serum/glucocorticoid regulated kinase 2b
irs1 insulin receptor substrate 1
nprl2 NPR2 like, GATOR1 complex subunit
akt3a v-akt murine thymoma viral oncogene homolog 3a
pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
rictorb RPTOR independent companion of MTOR, complex 2b
slc38a9 solute carrier family 38 member 9
depdc5 DEP domain containing 5, GATOR1 subcomplex subunit
wnt7aa wingless-type MMTV integration site family, member 7Aa
fzd3a frizzled class receptor 3a
nol9 nucleolar protein 9
fbxo33 F-box protein 33
LOC568110 protein Wnt-7a-like
lrp5 low density lipoprotein receptor-related protein 5
wnt3 wingless-type MMTV integration site family, member 3
slco3a1a solute carrier organic anion transporter family member 3A1a
dvl1a dishevelled segment polarity protein 1a
tti1 TELO2 interacting protein 1
prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit
hipk1b homeodomain interacting protein kinase 1b
rhebl1 Ras homolog, mTORC1 binding like 1
telo2 TEL2, telomere maintenance 2, homolog (S. cerevisiae)
fhip2b FHF complex subunit HOOK interacting protein 2B
rps6ka1 ribosomal protein S6 kinase a, polypeptide 1
sfxn3 sideroflexin 3
wnt16 wingless-type MMTV integration site family, member 16
LOC794462 insulin receptor substrate 2-B-like
slc3a2a solute carrier family 3 member 2a
fnip2 folliculin interacting protein 2
clip1a CAP-GLY domain containing linker protein 1a
fgfr4 fibroblast growth factor receptor 4
rragcb Ras-related GTP binding Cb
tmem199 transmembrane protein 199
slc7a8a solute carrier family 7 member 8a
ulk2 unc-51 like autophagy activating kinase 2
si:ch1073-459b3.2 si:ch1073-459b3.2
tsc1b TSC complex subunit 1b
wdr81 WD repeat domain 81
lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
mapkap1 MAPK associated protein 1
ldlrad2 low density lipoprotein receptor class A domain containing 2
bbln bublin coiled coil protein
atg2a autophagy related 2A
wdr59 WD repeat domain 59
Symbol Function*
CG14812 uncharacterized protein
CG14818 uncharacterized protein
raptor raptor
rictor rapamycin-insensitive companion of Tor
mio missing oocyte
Chd1 Chromodomain-helicase-DNA-binding protein 1
CG9044 uncharacterized protein
chic chickadee
wg wingless
Wnt6 Wnt oncogene analog 6
Wdr59 WD repeat domain 59
JhI-21 Juvenile hormone Inducible-21
Sos Son of sevenless
VhaSFD Vacuolar H[+]-ATPase SFD subunit
CG5110 uncharacterized protein
VhaAC45 Vacuolar H[+] ATPase AC45 accessory subunit
drk downstream of receptor kinase
Vha14-1 Vacuolar H[+] ATPase 14kD subunit 1
Rho1 Rho1
Vha44 Vacuolar H[+] ATPase 44kD subunit
Rap1 Rap1 GTPase
CG14977 uncharacterized protein
S6k Ribosomal protein S6 kinase
Ilp2 Insulin-like peptide 2
Ilp3 Insulin-like peptide 3
Ilp4 Insulin-like peptide 4
nudE nudE
Blos2 Biogenesis of lysosome-related organelles complex 1, subunit 2
Atg1 Autophagy-related 1
mnd minidiscs
Mo25 Mo25
CG3764 uncharacterized protein
Crtc CREB-regulated transcription coactivator
CG14184 uncharacterized protein
gig gigas
VhaM9.7-b Vacuolar H[+] ATPase M9.7 subunit b
Vha26 Vacuolar H[+]-ATPase 26kD subunit
elm ethanol sensitive with low memory
Taf1 TBP-associated factor 1
CD98hc CD98 heavy chain
Kdm2 Lysine (K)-specific demethylase 2
ATP6AP2 ATPase H+ transporting accessory protein 2
GC1 Glutamate Carrier 1
Vha55 Vacuolar H[+]-ATPase 55kD subunit
wntD wnt inhibitor of Dorsal
Akt1 Akt1
Vha13 Vacuolar H[+] ATPase 13kD subunit
InR Insulin-like receptor
Tsc1 Tsc1
Pten Phosphatase and tensin homolog
Vha36-1 Vacuolar H[+] ATPase 36kD subunit 1
Vha68-2 Vacuolar H[+] ATPase 68 kDa subunit 2
Tor Target of rapamycin
tws twins
CG17508 uncharacterized protein
chico chico
Rheb Ras homolog enriched in brain
Ilp5 Insulin-like peptide 5
SIFa SIFamide
rl rolled
CG40191 uncharacterized protein
mRpS5 mitochondrial ribosomal protein S5
Stlk Ste20-like kinase
CG17883 uncharacterized protein
CG34224 uncharacterized protein
Symbol Function*
mig-1 Uncharacterized protein
lin-17 Frizzled-4
vha-16 V-type proton ATPase subunit
spe-5 Vacuolar proton pump subunit B
aap-1 phosphoinositide kinase AdAPter subunit
let-363 Target of rapamycin homolog
erm-1 Moesin/ezrin/radixin homolog 1
vha-10 putative V-type proton ATPase subunit G
goa-1 Guanine nucleotide-binding protein G(o) subunit alpha
rskn-1 Putative ribosomal protein S6 kinase alpha-1;Ribosomal protein S6 kinase
ubr-5 UBR E3 ubiquitin ligase homolog
csnk-1 Casein kinase I gamma
gsk-3 Glycogen synthase kinase-3
C25H3.11 Ricin B-type lectin domain-containing protein
cdc-42 Cell division control protein 42 homolog
vha-4 Vacuolar H ATPase
mop-25.2 MO25-like protein 2
F54B3.1 Uncharacterized protein
vha-9 putative V-type proton ATPase subunit F
ife-5 Eukaryotic translation initiation factor 4E-5
daf-5 c-SKI_SMAD_bind domain-containing protein
daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;Receptor protein-tyrosine kinase
mpk-1 Mitogen-activated protein kinase mpk-1
T08A11.1 DEP domain-containing protein
ppm-2 putative protein phosphatase 2C T23F11.1
Y32H12A.8 WD_REPEATS_REGION domain-containing protein
clk-2 Telomere length regulation protein clk-2
vha-14 V-type proton ATPase subunit D
rsks-1 Ribosomal protein S6 kinase beta
fnip-2 FolliculiN Interacting Protein
vha-11 V-type proton ATPase subunit C
vha-3 V-type proton ATPase 16 kDa proteolipid subunit 2/3
ubc-13 Ubiquitin-conjugating enzyme E2 13
vha-19 Vacuolar H ATPase
fkh-7 Fork-head domain-containing protein
lin-45 Raf homolog serine/threonine-protein kinase
vha-8 Vacuolar H ATPase
K07H8.9 KH domain-containing protein
daf-15 Raptor_N domain-containing protein
R10H10.7 Uncharacterized protein
kin-4 Non-specific serine/threonine protein kinase
let-60 Ras protein let-60
rho-1 Ras-like GTP-binding protein rhoA
akt-1 Serine/threonine-protein kinase akt-1
lpin-1 LNS2 domain-containing protein
pptr-1 Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1
par-4 Serine/threonine-protein kinase par-4
unc-51 Serine/threonine-protein kinase unc-51
hif-1 Hypoxia-inducible factor 1
ife-4 Eukaryotic translation initiation factor 4E-4
vha-15 putative V-type proton ATPase subunit H 2
vha-12 putative V-type proton ATPase subunit B
ist-1 Insulin receptor SubsTrate homolog
sem-5 Sex muscle abnormal protein 5
mig-2 Uncharacterized protein
akt-2 Serine/threonine-protein kinase akt-2
aak-2 5'-AMP-activated protein kinase catalytic subunit alpha-2
nprl-3 GATOR complex protein NPRL3
lmtr-5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5
aakg-4 AMP-Activated protein Kinase Gamma subunit
sinh-1 Stress-activated map kinase-interacting protein 1 homolog
Y71H2AM.2 Phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Y92H12BR.7 Uncharacterized protein
vha-13 V-type proton ATPase catalytic subunit A
Symbol Function*
STRADB STE20 related adaptor beta
ATP6V0A1 ATPase H+ transporting V0 subunit a1
ATP6V1H ATPase H+ transporting V1 subunit H
BRAF B-Raf proto-oncogene, serine/threonine kinase
ATP6V1C1 ATPase H+ transporting V1 subunit C1
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2
GAS1 growth arrest specific 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RICTOR RPTOR independent companion of MTOR complex 2
TSC2 TSC complex subunit 2
LPIN2 lipin 2
MLST8 MTOR associated protein, LST8 homolog
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
E4F1 E4F transcription factor 1
SLC7A5 solute carrier family 7 member 5
WNT9A Wnt family member 9A
MIOS meiosis regulator for oocyte development
PHC3 polyhomeotic homolog 3
WDR24 WD repeat domain 24
SOX6 SRY-box transcription factor 6
FLCN folliculin
AKAP13 A-kinase anchoring protein 13
SORT1 sortilin 1
MAPK1 mitogen-activated protein kinase 1
RNF152 ring finger protein 152
MEA1 male-enhanced antigen 1
WNT10A Wnt family member 10A
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
TELO2 telomere maintenance 2
GRB2 growth factor receptor bound protein 2
COPS8 COP9 signalosome subunit 8
ATP6V1F ATPase H+ transporting V1 subunit F
CLIP1 CAP-Gly domain containing linker protein 1
RRAGD Ras related GTP binding D
GNAI2 G protein subunit alpha i2
FZD4 frizzled class receptor 4
FHIP2A FHF complex subunit HOOK interacting protein 2A
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
ATP6V1B2 ATPase H+ transporting V1 subunit B2
STK11 serine/threonine kinase 11
DVL1 dishevelled segment polarity protein 1
INSR insulin receptor
ADGRG6 adhesion G protein-coupled receptor G6
CAB39L calcium binding protein 39 like
COX7B cytochrome c oxidase subunit 7B
ANAPC2 anaphase promoting complex subunit 2
RHOA ras homolog family member A
IGF1R insulin like growth factor 1 receptor
FZD8 frizzled class receptor 8
CCNYL1 cyclin Y like 1
MAPK3 mitogen-activated protein kinase 3
NRAS NRAS proto-oncogene, GTPase
PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1
CHUK component of inhibitor of nuclear factor kappa B kinase complex
PCBP1 poly(rC) binding protein 1
TLCD4 TLC domain containing 4
ATP6V1A ATPase H+ transporting V1 subunit A
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PSMB6 proteasome 20S subunit beta 6
RPS6KA6 ribosomal protein S6 kinase A6
MAP2K1 mitogen-activated protein kinase kinase 1
FZD5 frizzled class receptor 5
GSK3B glycogen synthase kinase 3 beta
EIF4E2 eukaryotic translation initiation factor 4E family member 2
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
FZD3 frizzled class receptor 3
WNT7B Wnt family member 7B
TAF1C TATA-box binding protein associated factor, RNA polymerase I subunit C
RHEB Ras homolog, mTORC1 binding
TMEM222 transmembrane protein 222
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
DMWD DM1 locus, WD repeat containing
USP20 ubiquitin specific peptidase 20
PTPA protein phosphatase 2 phosphatase activator
RPS6KA2 ribosomal protein S6 kinase A2
SESN2 sestrin 2
KIAA2026 KIAA2026
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
STRADA STE20 related adaptor alpha
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
CHMP6 charged multivesicular body protein 6
PRKCA protein kinase C alpha
DUSP2 dual specificity phosphatase 2
NCOA1 nuclear receptor coactivator 1
TBC1D17 TBC1 domain family member 17
AKT1S1 AKT1 substrate 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
ELL elongation factor for RNA polymerase II
WNT5B Wnt family member 5B
RPS6KB2 ribosomal protein S6 kinase B2
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
MAP2K2 mitogen-activated protein kinase kinase 2
DVL3 dishevelled segment polarity protein 3
FNIP1 folliculin interacting protein 1
RRAGA Ras related GTP binding A
LOC106998903 ragulator complex protein LAMTOR5
PRR5 proline rich 5
Symbol Function*
ATP6V0E1 ATPase H+ transporting V0 subunit e1
KRAS KRAS proto-oncogene, GTPase
RHOA ras homolog family member A
IGF1R insulin like growth factor 1 receptor
RRAGD Ras related GTP binding D
ATP6V1C1 ATPase H+ transporting V1 subunit C1
ATP6V1F ATPase H+ transporting V1 subunit F
SNX10 sorting nexin 10
FNIP2 folliculin interacting protein 2
ATP6V1C2 ATPase H+ transporting V1 subunit C2
ARHGAP18 Rho GTPase activating protein 18
PSAT1 phosphoserine aminotransferase 1
NPRL2 NPR2 like, GATOR1 complex subunit
APEH acylaminoacyl-peptide hydrolase
DDA1 DET1 and DDB1 associated 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
LRP6 LDL receptor related protein 6
KDM5A lysine demethylase 5A
ATP6V1E1 ATPase H+ transporting V1 subunit E1
CA2 carbonic anhydrase 2
MAP2K1 mitogen-activated protein kinase kinase 1
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
PPA2 inorganic pyrophosphatase 2
KLHL24 kelch like family member 24
STRADB STE20 related adaptor beta
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
ELOB elongin B
PDPK1 3-phosphoinositide dependent protein kinase 1
TSC2 TSC complex subunit 2
WDR24 WD repeat domain 24
RHOT2 ras homolog family member T2
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
ATP6V1D ATPase H+ transporting V1 subunit D
FNIP1 folliculin interacting protein 1
FZD1 frizzled class receptor 1
WNT2B Wnt family member 2B
GRB2 growth factor receptor bound protein 2
MEN1 menin 1
SLC3A2 solute carrier family 3 member 2
FKBP8 FKBP prolyl isomerase 8
INSR insulin receptor
FZD4 frizzled class receptor 4
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
TRIB3 tribbles pseudokinase 3
ATP6V1B2 ATPase H+ transporting V1 subunit B2
ITGA5 integrin subunit alpha 5
ATP6V1H ATPase H+ transporting V1 subunit H
SESN2 sestrin 2
EIF4E eukaryotic translation initiation factor 4E
ATP6V1A ATPase H+ transporting V1 subunit A
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
SLC7A5 solute carrier family 7 member 5
UBN1 ubinuclein 1
TELO2 telomere maintenance 2
LMF1 lipase maturation factor 1
MAPKAPK2 MAPK activated protein kinase 2
AKT1 AKT serine/threonine kinase 1
ARF4 ADP ribosylation factor 4
SEC13 SEC13 homolog, nuclear pore and COPII coat complex component
GRB10 growth factor receptor bound protein 10
TCTA T cell leukemia translocation altered
BRI3 brain protein I3
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
RPS6KB2 ribosomal protein S6 kinase B2
MLST8 MTOR associated protein, LST8 homolog
NPRL3 NPR3 like, GATOR1 complex subunit
MAP2K2 mitogen-activated protein kinase kinase 2
WNT2 Wnt family member 2
RPS6KA2 ribosomal protein S6 kinase A2
ATP6V1G1 ATPase H+ transporting V1 subunit G1
EPHX3 epoxide hydrolase 3
RRAGC Ras related GTP binding C
HSBP1 heat shock factor binding protein 1
LOC119870648 pantetheinase-like
Symbol Function*
HRAS HRas proto-oncogene, GTPase
KRAS KRAS proto-oncogene, GTPase
INSR insulin receptor
NEDD8 NEDD8 ubiquitin like modifier
MAP2K1 mitogen-activated protein kinase kinase 1
GSK3B glycogen synthase kinase 3 beta
ATP6V1E1 ATPase H+ transporting V1 subunit E1
ATP6V1F ATPase H+ transporting V1 subunit F
PHF3 PHD finger protein 3
SIPA1L1 signal induced proliferation associated 1 like 1
TSC2 TSC complex subunit 2
ATP6V1C1 ATPase H+ transporting V1 subunit C1
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
UBE2H ubiquitin conjugating enzyme E2 H
LPIN2 lipin 2
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
FNIP2 folliculin interacting protein 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
RASGEF1B RasGEF domain family member 1B
MTMR3 myotubularin related protein 3
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
WNT16 Wnt family member 16
AVL9 AVL9 cell migration associated
TACC2 transforming acidic coiled-coil containing protein 2
ATP6V1A ATPase H+ transporting V1 subunit A
CLIP1 CAP-Gly domain containing linker protein 1
ETHE1 ETHE1 persulfide dioxygenase
ATP6V1B2 ATPase H+ transporting V1 subunit B2
FNIP1 folliculin interacting protein 1
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
FZD4 frizzled class receptor 4
WNT10B Wnt family member 10B
WNT1 Wnt family member 1
DVL2 dishevelled segment polarity protein 2
SEH1L SEH1 like nucleoporin
FLRT3 fibronectin leucine rich transmembrane protein 3
WNT4 Wnt family member 4
ATP6V1H ATPase H+ transporting V1 subunit H
HPRT1 hypoxanthine phosphoribosyltransferase 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RICTOR RPTOR independent companion of MTOR complex 2
CPSF1 cleavage and polyadenylation specific factor 1
NRBP1 nuclear receptor binding protein 1
RALGAPB Ral GTPase activating protein non-catalytic subunit beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
RRAGA Ras related GTP binding A
FZD5 frizzled class receptor 5
MTMR1 myotubularin related protein 1
ULK1 unc-51 like autophagy activating kinase 1
ATP6V1G1 ATPase H+ transporting V1 subunit G1
EIF4E2 eukaryotic translation initiation factor 4E family member 2
TMEM251 transmembrane protein 251
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
SNX10 sorting nexin 10
DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit
PDPK1 3-phosphoinositide dependent protein kinase 1
MIOS meiosis regulator for oocyte development
WNT9A Wnt family member 9A


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