KEGG 04912 GnRH signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04912 GnRH signaling pathway 33
hsa04750 Inflammatory mediator regulation of TRP channels 22
hsa04921 Oxytocin signaling pathway 20
hsa04270 Vascular smooth muscle contraction 19
hsa05163 Human cytomegalovirus infection 19
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04912 GnRH signaling pathway 29
mmu05163 Human cytomegalovirus infection 22
mmu05200 Pathways in cancer 21
mmu04921 Oxytocin signaling pathway 20
mmu05170 Human immunodeficiency virus 1 infection 20
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04912 GnRH signaling pathway 33
rno05200 Pathways in cancer 26
rno04010 MAPK signaling pathway 23
rno04921 Oxytocin signaling pathway 23
rno05022 Pathways of neurodegeneration - multiple diseases 23
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04912 GnRH signaling pathway 36
gga04010 MAPK signaling pathway 28
gga04270 Vascular smooth muscle contraction 17
gga04261 Adrenergic signaling in cardiomyocytes 14
gga04540 Gap junction 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04912 GnRH signaling pathway 58
dre04010 MAPK signaling pathway 35
dre04270 Vascular smooth muscle contraction 29
dre04261 Adrenergic signaling in cardiomyocytes 29
dre04114 Oocyte meiosis 26
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04912 GnRH signaling pathway 25
mcc04010 MAPK signaling pathway 18
mcc05200 Pathways in cancer 17
mcc04935 Growth hormone synthesis, secretion and action 15
mcc05161 Hepatitis B 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04912 GnRH signaling pathway 21
cfa05200 Pathways in cancer 16
cfa04921 Oxytocin signaling pathway 15
cfa04010 MAPK signaling pathway 14
cfa04915 Estrogen signaling pathway 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04912 GnRH signaling pathway 28
fca05200 Pathways in cancer 22
fca04921 Oxytocin signaling pathway 21
fca04915 Estrogen signaling pathway 18
fca04916 Melanogenesis 18
Gene list in the network
Symbol Function*
ADCY1 adenylate cyclase 1
ADCY7 adenylate cyclase 7
ADCY9 adenylate cyclase 9
ALDH3B2 aldehyde dehydrogenase 3 family member B2
ATF3 activating transcription factor 3
CACNA1C calcium voltage-gated channel subunit alpha1 C
CALML3 calmodulin like 3
CAMK2B calcium/calmodulin dependent protein kinase II beta
MAPK14 mitogen-activated protein kinase 14
HBEGF heparin binding EGF like growth factor
EGR1 early growth response 1
PTK2B protein tyrosine kinase 2 beta
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
GNAS GNAS complex locus
ARHGAP35 Rho GTPase activating protein 35
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
ITPR2 inositol 1,4,5-trisphosphate receptor type 2
ITPR3 inositol 1,4,5-trisphosphate receptor type 3
JUN Jun proto-oncogene, AP-1 transcription factor subunit
KCND3 potassium voltage-gated channel subfamily D member 3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MMP2 matrix metallopeptidase 2
MMP14 matrix metallopeptidase 14
PLCB2 phospholipase C beta 2
PLCB3 phospholipase C beta 3
PLD2 phospholipase D2
PRKCA protein kinase C alpha
PRKCD protein kinase C delta
MAPK11 mitogen-activated protein kinase 11
MAPK13 mitogen-activated protein kinase 13
MAP2K2 mitogen-activated protein kinase kinase 2
PTPN6 protein tyrosine phosphatase non-receptor type 6
MAPK12 mitogen-activated protein kinase 12
MAP2K4 mitogen-activated protein kinase kinase 4
USF2 upstream transcription factor 2, c-fos interacting
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
ZHX3 zinc fingers and homeoboxes 3
TBC1D2B TBC1 domain family member 2B
CAB39 calcium binding protein 39
CALML5 calmodulin like 5
LCE3D late cornified envelope 3D
PLA2G4E phospholipase A2 group IVE
ADCY4 adenylate cyclase 4
PLA2G4F phospholipase A2 group IVF
PLA2G4D phospholipase A2 group IVD
LOC105371058 uncharacterized LOC105371058
Symbol Function*
Adcy6 adenylate cyclase 6
Adcy7 adenylate cyclase 7
Adcy9 adenylate cyclase 9
Calm1 calmodulin 1
Calm2 calmodulin 2
Calm3 calmodulin 3
Camk2g calcium/calmodulin-dependent protein kinase II gamma
Egr1 early growth response 1
Fos FBJ osteosarcoma oncogene
Gna11 guanine nucleotide binding protein, alpha 11
Grb2 growth factor receptor bound protein 2
Hras Harvey rat sarcoma virus oncogene
Itpr2 inositol 1,4,5-triphosphate receptor 2
Jun jun proto-oncogene
Ksr1 kinase suppressor of ras 1
Mbd3 methyl-CpG binding domain protein 3
Mmp14 matrix metallopeptidase 14 (membrane-inserted)
Mmp2 matrix metallopeptidase 2
Pitpna phosphatidylinositol transfer protein, alpha
Prkca protein kinase C, alpha
Plcb2 phospholipase C, beta 2
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Mapk11 mitogen-activated protein kinase 11
Ptk2b PTK2 protein tyrosine kinase 2 beta
Map2k1 mitogen-activated protein kinase kinase 1
Map2k2 mitogen-activated protein kinase kinase 2
Map2k4 mitogen-activated protein kinase kinase 4
Mapk1 mitogen-activated protein kinase 1
Mapk14 mitogen-activated protein kinase 14
Mapk9 mitogen-activated protein kinase 9
Mapk12 mitogen-activated protein kinase 12
Rnf14 ring finger protein 14
Them5 thioesterase superfamily member 5
Calml3 calmodulin-like 3
Calm4 calmodulin 4
Plekha2 pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Hdac10 histone deacetylase 10
Abhd17a abhydrolase domain containing 17A
Gm94 predicted gene 94
Pla2g4f phospholipase A2, group IVF
Rasal3 RAS protein activator like 3
Cracr2a calcium release activated channel regulator 2A
Trim56 tripartite motif-containing 56
Symbol Function*
Cacna1c calcium voltage-gated channel subunit alpha1 C
Calm1 calmodulin 1
Calm3 calmodulin 3
Camk2b calcium/calmodulin-dependent protein kinase II beta
Camk2d calcium/calmodulin-dependent protein kinase II delta
Egr1 early growth response 1
Jun Jun proto-oncogene, AP-1 transcription factor subunit
Kras KRAS proto-oncogene, GTPase
Nras NRAS proto-oncogene, GTPase
Plcb1 phospholipase C beta 1
Prkcb protein kinase C, beta
Plcb4 phospholipase C, beta 4
Itpr1 inositol 1,4,5-trisphosphate receptor, type 1
Atf3 activating transcription factor 3
Hbegf heparin-binding EGF-like growth factor
Prkaca protein kinase cAMP-activated catalytic subunit alpha
Rasgrp1 RAS guanyl releasing protein 1
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Ptk2b protein tyrosine kinase 2 beta
Mapk9 mitogen-activated protein kinase 9
Calm2 calmodulin 2
Map2k2 mitogen activated protein kinase kinase 2
Mapk12 mitogen-activated protein kinase 12
Cdc42 cell division cycle 42
Adcy5 adenylate cyclase 5
Rab2a RAB2A, member RAS oncogene family
Mtpn myotrophin
Grb2 growth factor receptor bound protein 2
Mmp2 matrix metallopeptidase 2
Mmp14 matrix metallopeptidase 14
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Ryr1 ryanodine receptor 1
Mapk1 mitogen activated protein kinase 1
Map2k1 mitogen activated protein kinase kinase 1
Ipmk inositol polyphosphate multikinase
Map2k4 mitogen activated protein kinase kinase 4
Actr2 actin related protein 2
Hras HRas proto-oncogene, GTPase
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Fbxo11 F-box protein 11
Mlf2 myeloid leukemia factor 2
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Fos Fos proto-oncogene, AP-1 transcription factor subunit
Rac1 Rac family small GTPase 1
Ier2 immediate early response 2
Akap11 A-kinase anchoring protein 11
Cacna1s calcium voltage-gated channel subunit alpha1 S
Mapk11 mitogen-activated protein kinase 11
Symbol Function*
EGR1 early growth response 1
CAMK2B calcium/calmodulin dependent protein kinase II beta
DUSP1 dual specificity phosphatase 1
TRIB2 tribbles pseudokinase 2
GRB2 growth factor receptor bound protein 2
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
CALM2 calmodulin 2
CDC42 cell division cycle 42
MAPK9 mitogen-activated protein kinase 9
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
FOS Fos proto-oncogene, AP-1 transcription factor subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
MAP2K1 mitogen-activated protein kinase kinase 1
ATP2B2 ATPase plasma membrane Ca2+ transporting 2
PRKCB protein kinase C beta
PLCB4 phospholipase C beta 4
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK11 mitogen-activated protein kinase 11
RASSF5 Ras association domain family member 5
MAP3K3 mitogen-activated protein kinase kinase kinase 3
ARF1 ADP ribosylation factor 1
LOC420419 mitogen-activated protein kinase kinase kinase 3-like
KLF6 Kruppel like factor 6
ADCY1 adenylate cyclase 1
MAP3K4 mitogen-activated protein kinase kinase kinase 4
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTK2B protein tyrosine kinase 2 beta
CAMK2D calcium/calmodulin dependent protein kinase II delta
PLA2G4EL6 phospholipase A2 group IVE-like 6
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
PRKACB protein kinase cAMP-activated catalytic subunit beta
JUN Jun proto-oncogene, AP-1 transcription factor subunit
ARMC8 armadillo repeat containing 8
SPHKAP SPHK1 interactor, AKAP domain containing
PLD1 phospholipase D1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
PLCB1 phospholipase C beta 1
CTNND1 catenin delta 1
LOC428870 cytosolic phospholipase A2 epsilon-like
PLA2G4F phospholipase A2 group IVF
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
LOC771552 cytosolic phospholipase A2 epsilon-like
PLA2G4EL2 phospholipase A2 group IVE-like 2
ADAP1L arf-GAP with dual PH domain-containing protein 1-like
PLA2G4B phospholipase A2 group IVB
ZBTB44 zinc finger and BTB domain containing 44
LOC107050028 adenylate cyclase type 6-like
LOC107050029 serine/arginine repetitive matrix protein 1-like
CRK CRK proto-oncogene, adaptor protein
Symbol Function*
egr1 early growth response 1
pla2g4aa phospholipase A2, group IVAa (cytosolic, calcium-dependent)
mapk12a mitogen-activated protein kinase 12a
raf1a Raf-1 proto-oncogene, serine/threonine kinase a
atp1b3b ATPase Na+/K+ transporting subunit beta 3b
map2k6 mitogen-activated protein kinase kinase 6
calm2b calmodulin 2b, (phosphorylase kinase, delta)
ptk2bb protein tyrosine kinase 2 beta, b
atp6v0b ATPase H+ transporting V0 subunit b
calm3b calmodulin 3b (phosphorylase kinase, delta)
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
map3k4 mitogen-activated protein kinase kinase kinase 4
calm3a calmodulin 3a (phosphorylase kinase, delta)
gnai2b guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
prkcda protein kinase C, delta a
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
jun Jun proto-oncogene, AP-1 transcription factor subunit
calm2a calmodulin 2a (phosphorylase kinase, delta)
cdc42 cell division cycle 42
mmp2 matrix metallopeptidase 2
ier5 immediate early response 5
timp2a TIMP metallopeptidase inhibitor 2a
mapk1 mitogen-activated protein kinase 1
birc2 baculoviral IAP repeat containing 2
mmp14a matrix metallopeptidase 14a (membrane-inserted)
zgc:55558 zgc:55558
prkcbb protein kinase C, beta b
fosab v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
mapk3 mitogen-activated protein kinase 3
lhb luteinizing hormone subunit beta
cga glycoprotein hormones, alpha polypeptide
dock8 dedicator of cytokinesis 8
cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a
cacna1db calcium channel, voltage-dependent, L type, alpha 1D subunit, b
grb2b growth factor receptor-bound protein 2b
atf4a activating transcription factor 4a
calm1a calmodulin 1a
map2k1 mitogen-activated protein kinase kinase 1
mapk11 mitogen-activated protein kinase 11
tspan33a tetraspanin 33a
zgc:92360 zgc:92360
camk2d1 calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
gna11b guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
erlin1 ER lipid raft associated 1
eif4e2 eukaryotic translation initiation factor 4E family member 2
itprid2 ITPR interacting domain containing 2
cdc42l2 cell division cycle 42 like 2
atf4b activating transcription factor 4b
raf1b Raf-1 proto-oncogene, serine/threonine kinase b
mapk12b mitogen-activated protein kinase 12b
pla2g4ab phospholipase A2, group IVAb (cytosolic, calcium-dependent)
tesk1b testis associated actin remodelling kinase 1b
si:ch211-132f19.7 si:ch211-132f19.7
adcy6b adenylate cyclase 6b
pkn1a protein kinase N1a
sos2 son of sevenless homolog 2 (Drosophila)
ddit3 DNA-damage-inducible transcript 3
camk2b1 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
zgc:171775 zgc:171775
itpr2 inositol 1,4,5-trisphosphate receptor, type 2
prkacbb protein kinase, cAMP-dependent, catalytic, beta b
map2k2a mitogen-activated protein kinase kinase 2a
prkacaa protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
pld2 phospholipase D2
trpm3 transient receptor potential cation channel, subfamily M, member 3
mmp14b matrix metallopeptidase 14b (membrane-inserted)
elk1 ETS transcription factor ELK1
atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
adcy7 adenylate cyclase 7
map2k4b mitogen-activated protein kinase kinase 4b
inpp5l inositol polyphosphate-5-phosphatase L
cnot7 CCR4-NOT transcription complex, subunit 7
camk2g1 calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
cacna1fa calcium channel, voltage-dependent, L type, alpha 1F subunit a
pcnx1 pecanex 1
LOC794598 phospholipid phosphatase 1-like
itpr3 inositol 1,4,5-trisphosphate receptor, type 3
mapk13 mitogen-activated protein kinase 13
mark2b MAP/microtubule affinity-regulating kinase 2b
prkcba protein kinase C, beta a
LOC100149080 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like
mapk9 mitogen-activated protein kinase 9
itpr1b inositol 1,4,5-trisphosphate receptor, type 1b
cracr2aa calcium release activated channel regulator 2Aa
clmna calmin a
ier2b immediate early response 2b
fermt1 FERM domain containing kindlin 1
si:ch211-203d1.3 si:ch211-203d1.3
LOC110438068 glycoprotein hormones alpha chain-like
Symbol Function*
STX1A syntaxin 1A
CX3CL1 C-X3-C motif chemokine ligand 1
MAP2K6 mitogen-activated protein kinase kinase 6
NPEPPS aminopeptidase puromycin sensitive
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
HBEGF heparin binding EGF like growth factor
MMP2 matrix metallopeptidase 2
CALM1 calmodulin 1
MAPK1 mitogen-activated protein kinase 1
GRB2 growth factor receptor bound protein 2
FOS Fos proto-oncogene, AP-1 transcription factor subunit
CAMK2D calcium/calmodulin dependent protein kinase II delta
DUSP1 dual specificity phosphatase 1
RIC8B RIC8 guanine nucleotide exchange factor B
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
GNAQ G protein subunit alpha q
POMK protein O-mannose kinase
CDC42 cell division cycle 42
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP2K1 mitogen-activated protein kinase kinase 1
CAMK2A calcium/calmodulin dependent protein kinase II alpha
MMP14 matrix metallopeptidase 14
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
MAPK12 mitogen-activated protein kinase 12
MAPK9 mitogen-activated protein kinase 9
WDTC1 WD and tetratricopeptide repeats 1
MAPK11 mitogen-activated protein kinase 11
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
JUN Jun proto-oncogene, AP-1 transcription factor subunit
EGR1 early growth response 1
IER2 immediate early response 2
KIAA2026 KIAA2026
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
NCOA1 nuclear receptor coactivator 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
CACNA1C calcium voltage-gated channel subunit alpha1 C
CTDNEP1 CTD nuclear envelope phosphatase 1
DYNLRB1 dynein light chain roadblock-type 1
Symbol Function*
PRKACA protein kinase cAMP-activated catalytic subunit alpha
NRAS NRAS proto-oncogene, GTPase
GNAQ G protein subunit alpha q
GNAS GNAS complex locus
MAP3K4 mitogen-activated protein kinase kinase kinase 4
DDA1 DET1 and DDB1 associated 1
MAPK8 mitogen-activated protein kinase 8
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
MAP3K3 mitogen-activated protein kinase kinase kinase 3
EGR1 early growth response 1
CAMK2B calcium/calmodulin dependent protein kinase II beta
GRB2 growth factor receptor bound protein 2
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
FKBP8 FKBP prolyl isomerase 8
KLHL40 kelch like family member 40
CALML5 calmodulin like 5
ADCY7 adenylate cyclase 7
CACNA1S calcium voltage-gated channel subunit alpha1 S
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
FOS Fos proto-oncogene, AP-1 transcription factor subunit
MYOM2 myomesin 2
MAPK12 mitogen-activated protein kinase 12
PLA2G4D phospholipase A2 group IVD
JUN Jun proto-oncogene, AP-1 transcription factor subunit
RAPSN receptor associated protein of the synapse
MAP2K2 mitogen-activated protein kinase kinase 2
CNFN cornifelin
PLCB2 phospholipase C beta 2
MTMR3 myotubularin related protein 3
LOC102153034 calmodulin-like protein 3
BTK Bruton tyrosine kinase
PLEKHM1 pleckstrin homology and RUN domain containing M1
KANSL1 KAT8 regulatory NSL complex subunit 1
Symbol Function*
HRAS HRas proto-oncogene, GTPase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
CAMK2A calcium/calmodulin dependent protein kinase II alpha
MAPK9 mitogen-activated protein kinase 9
TNS1 tensin 1
PJA2 praja ring finger ubiquitin ligase 2
FMNL1 formin like 1
DDHD2 DDHD domain containing 2
MAPK1 mitogen-activated protein kinase 1
SCN4B sodium voltage-gated channel beta subunit 4
ITPR3 inositol 1,4,5-trisphosphate receptor type 3
TRIM72 tripartite motif containing 72
EGR1 early growth response 1
NAPA NSF attachment protein alpha
PRKCB protein kinase C beta
LY9 lymphocyte antigen 9
MMP14 matrix metallopeptidase 14
MAPKAPK2 MAPK activated protein kinase 2
PLCB2 phospholipase C beta 2
CALM3 calmodulin 3
ADCY6 adenylate cyclase 6
LOC101091541 phosphatidylinositol phosphatase PTPRQ
PTK2B protein tyrosine kinase 2 beta
PLD2 phospholipase D2
PLCB3 phospholipase C beta 3
HBEGF heparin binding EGF like growth factor
ADCY7 adenylate cyclase 7
ADCY2 adenylate cyclase 2
CALM1 calmodulin 1
FOSB FosB proto-oncogene, AP-1 transcription factor subunit
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
JUN Jun proto-oncogene, AP-1 transcription factor subunit
CAMK2G calcium/calmodulin dependent protein kinase II gamma
MTMR1 myotubularin related protein 1
CAMK2B calcium/calmodulin dependent protein kinase II beta
CALML4 calmodulin like 4
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
ADCY5 adenylate cyclase 5
BCR BCR activator of RhoGEF and GTPase
LOC111556187 calmodulin-like protein 4


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