| Representative coexpressed gene network |

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| hsa05200 |
Pathways in cancer |
52 |
 |
| hsa05224 |
Breast cancer |
52 |
 |
| hsa05226 |
Gastric cancer |
36 |
 |
| hsa05225 |
Hepatocellular carcinoma |
32 |
 |
| hsa05165 |
Human papillomavirus infection |
31 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| mmu05224 |
Breast cancer |
65 |
 |
| mmu05200 |
Pathways in cancer |
63 |
 |
| mmu05226 |
Gastric cancer |
46 |
 |
| mmu05225 |
Hepatocellular carcinoma |
45 |
 |
| mmu05165 |
Human papillomavirus infection |
43 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| rno05200 |
Pathways in cancer |
61 |
 |
| rno05224 |
Breast cancer |
60 |
 |
| rno05225 |
Hepatocellular carcinoma |
43 |
 |
| rno05226 |
Gastric cancer |
43 |
 |
| rno05165 |
Human papillomavirus infection |
41 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| mcc05224 |
Breast cancer |
54 |
 |
| mcc05200 |
Pathways in cancer |
53 |
 |
| mcc05165 |
Human papillomavirus infection |
38 |
 |
| mcc05226 |
Gastric cancer |
36 |
 |
| mcc05225 |
Hepatocellular carcinoma |
36 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| cfa05200 |
Pathways in cancer |
49 |
 |
| cfa05224 |
Breast cancer |
48 |
 |
| cfa05226 |
Gastric cancer |
33 |
 |
| cfa05225 |
Hepatocellular carcinoma |
32 |
 |
| cfa05165 |
Human papillomavirus infection |
27 |
 |
|

| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| fca05224 |
Breast cancer |
49 |
 |
| fca05200 |
Pathways in cancer |
48 |
 |
| fca05226 |
Gastric cancer |
38 |
 |
| fca05225 |
Hepatocellular carcinoma |
37 |
 |
| fca01522 |
Endocrine resistance |
30 |
 |
|
| Gene list in the network |
|
Symbol |
Function* |
| |
JAG1 |
jagged canonical Notch ligand 1 |
| |
AKT2 |
AKT serine/threonine kinase 2 |
| |
ARAF |
A-Raf proto-oncogene, serine/threonine kinase |
| |
BAX |
BCL2 associated X, apoptosis regulator |
| |
CAMK4 |
calcium/calmodulin dependent protein kinase IV |
| |
DDB2 |
damage specific DNA binding protein 2 |
| |
GADD45A |
growth arrest and DNA damage inducible alpha |
| |
DUSP1 |
dual specificity phosphatase 1 |
| |
E2F1 |
E2F transcription factor 1 |
| |
E2F2 |
E2F transcription factor 2 |
| |
FDXR |
ferredoxin reductase |
| |
FGF5 |
fibroblast growth factor 5 |
| |
FGF7 |
fibroblast growth factor 7 |
| |
FGF10 |
fibroblast growth factor 10 |
| |
FGFR1 |
fibroblast growth factor receptor 1 |
| |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
| |
FOSB |
FosB proto-oncogene, AP-1 transcription factor subunit |
| |
FZD2 |
frizzled class receptor 2 |
| |
HES1 |
hes family bHLH transcription factor 1 |
| |
IGF1R |
insulin like growth factor 1 receptor |
| |
JAG2 |
jagged canonical Notch ligand 2 |
| |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
| |
JUNB |
JunB proto-oncogene, AP-1 transcription factor subunit |
| |
MSX1 |
msh homeobox 1 |
| |
GADD45B |
growth arrest and DNA damage inducible beta |
| |
NOTCH1 |
notch receptor 1 |
| |
NOTCH3 |
notch receptor 3 |
| |
NOTCH4 |
notch receptor 4 |
| |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| |
PPP1R3D |
protein phosphatase 1 regulatory subunit 3D |
| |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
| |
SOS2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
TCF7 |
transcription factor 7 |
| |
TCF7L2 |
transcription factor 7 like 2 |
| |
USF2 |
upstream transcription factor 2, c-fos interacting |
| |
WNT2 |
Wnt family member 2 |
| |
WNT3 |
Wnt family member 3 |
| |
WNT5A |
Wnt family member 5A |
| |
WNT6 |
Wnt family member 6 |
| |
WNT7B |
Wnt family member 7B |
| |
WNT11 |
Wnt family member 11 |
| |
WNT9A |
Wnt family member 9A |
| |
ZFP36 |
ZFP36 ring finger protein |
| |
AXIN2 |
axin 2 |
| |
FZD9 |
frizzled class receptor 9 |
| |
NCOA1 |
nuclear receptor coactivator 1 |
| |
FGF18 |
fibroblast growth factor 18 |
| |
NTN1 |
netrin 1 |
| |
CELSR1 |
cadherin EGF LAG seven-pass G-type receptor 1 |
| |
FGF19 |
fibroblast growth factor 19 |
| |
FRAT1 |
FRAT regulator of WNT signaling pathway 1 |
| |
GADD45G |
growth arrest and DNA damage inducible gamma |
| |
EDAR |
ectodysplasin A receptor |
| |
RBPMS |
RNA binding protein, mRNA processing factor |
| |
FZD10 |
frizzled class receptor 10 |
| |
ATP11B |
ATPase phospholipid transporting 11B (putative) |
| |
MED13L |
mediator complex subunit 13L |
| |
FRAT2 |
FRAT regulator of WNT signaling pathway 2 |
| |
HEY1 |
hes related family bHLH transcription factor with YRPW motif 1 |
| |
HEY2 |
hes related family bHLH transcription factor with YRPW motif 2 |
| |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
| |
HEYL |
hes related family bHLH transcription factor with YRPW motif like |
| |
DLL1 |
delta like canonical Notch ligand 1 |
| |
RPS27L |
ribosomal protein S27 like |
| |
LEF1 |
lymphoid enhancer binding factor 1 |
| |
DLL4 |
delta like canonical Notch ligand 4 |
| |
WNT10A |
Wnt family member 10A |
| |
WNT5B |
Wnt family member 5B |
| |
TCF7L1 |
transcription factor 7 like 1 |
| |
COL6A6 |
collagen type VI alpha 6 chain |
| |
ISM1 |
isthmin 1 |
| |
NOTUM |
notum, palmitoleoyl-protein carboxylesterase |
| |
CCBE1 |
collagen and calcium binding EGF domains 1 |
| |
ZNF367 |
zinc finger protein 367 |
| |
IER5L |
immediate early response 5 like |
| |
NRARP |
NOTCH regulated ankyrin repeat protein |
|
|
Symbol |
Function* |
| |
Akt1 |
thymoma viral proto-oncogene 1 |
| |
Akt2 |
thymoma viral proto-oncogene 2 |
| |
Apc |
APC, WNT signaling pathway regulator |
| |
Ar |
androgen receptor |
| |
Araf |
Araf proto-oncogene, serine/threonine kinase |
| |
Atf3 |
activating transcription factor 3 |
| |
Axin2 |
axin 2 |
| |
Bak1 |
BCL2-antagonist/killer 1 |
| |
Bax |
BCL2-associated X protein |
| |
Cdh5 |
cadherin 5 |
| |
Cdk6 |
cyclin-dependent kinase 6 |
| |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A (P21) |
| |
Dll1 |
delta like canonical Notch ligand 1 |
| |
Dll3 |
delta like canonical Notch ligand 3 |
| |
Ephb3 |
Eph receptor B3 |
| |
Ephb4 |
Eph receptor B4 |
| |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
| |
Esr1 |
estrogen receptor 1 (alpha) |
| |
Fgf15 |
fibroblast growth factor 15 |
| |
Fgf18 |
fibroblast growth factor 18 |
| |
Flt4 |
FMS-like tyrosine kinase 4 |
| |
Fos |
FBJ osteosarcoma oncogene |
| |
Frat1 |
frequently rearranged in advanced T cell lymphomas |
| |
Fzd1 |
frizzled class receptor 1 |
| |
Fzd7 |
frizzled class receptor 7 |
| |
Fzd8 |
frizzled class receptor 8 |
| |
Fzd9 |
frizzled class receptor 9 |
| |
Gas1 |
growth arrest specific 1 |
| |
Hes1 |
hes family bHLH transcription factor 1 |
| |
Hes5 |
hes family bHLH transcription factor 5 |
| |
Hey1 |
hairy/enhancer-of-split related with YRPW motif 1 |
| |
Hey2 |
hairy/enhancer-of-split related with YRPW motif 2 |
| |
Hras |
Harvey rat sarcoma virus oncogene |
| |
Ier2 |
immediate early response 2 |
| |
Jun |
jun proto-oncogene |
| |
Junb |
jun B proto-oncogene |
| |
Lef1 |
lymphoid enhancer binding factor 1 |
| |
Lrp5 |
low density lipoprotein receptor-related protein 5 |
| |
Mbd3 |
methyl-CpG binding domain protein 3 |
| |
Msx2 |
msh homeobox 2 |
| |
Gadd45b |
growth arrest and DNA-damage-inducible 45 beta |
| |
Notch1 |
notch 1 |
| |
Notch3 |
notch 3 |
| |
Notch4 |
notch 4 |
| |
Nras |
neuroblastoma ras oncogene |
| |
Pgr |
progesterone receptor |
| |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| |
Pten |
phosphatase and tensin homolog |
| |
Dusp1 |
dual specificity phosphatase 1 |
| |
Shc3 |
src homology 2 domain-containing transforming protein C3 |
| |
Sos2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
Sox3 |
SRY (sex determining region Y)-box 3 |
| |
Sp1 |
trans-acting transcription factor 1 |
| |
Tcf7 |
transcription factor 7, T cell specific |
| |
Tcf7l1 |
transcription factor 7 like 1 (T cell specific, HMG box) |
| |
Tcf7l2 |
transcription factor 7 like 2, T cell specific, HMG box |
| |
Nr2e1 |
nuclear receptor subfamily 2, group E, member 1 |
| |
Trp53 |
transformation related protein 53 |
| |
Wnt10a |
wingless-type MMTV integration site family, member 10A |
| |
Wnt10b |
wingless-type MMTV integration site family, member 10B |
| |
Wnt4 |
wingless-type MMTV integration site family, member 4 |
| |
Wnt5a |
wingless-type MMTV integration site family, member 5A |
| |
Wnt5b |
wingless-type MMTV integration site family, member 5B |
| |
Wnt6 |
wingless-type MMTV integration site family, member 6 |
| |
Wnt7a |
wingless-type MMTV integration site family, member 7A |
| |
Wnt7b |
wingless-type MMTV integration site family, member 7B |
| |
Apc2 |
APC regulator of WNT signaling pathway 2 |
| |
Gadd45g |
growth arrest and DNA-damage-inducible 45 gamma |
| |
Map2k2 |
mitogen-activated protein kinase kinase 2 |
| |
Ror2 |
receptor tyrosine kinase-like orphan receptor 2 |
| |
Gprin1 |
G protein-regulated inducer of neurite outgrowth 1 |
| |
Phlda3 |
pleckstrin homology like domain, family A, member 3 |
| |
Dll4 |
delta like canonical Notch ligand 4 |
| |
Heyl |
hairy/enhancer-of-split related with YRPW motif-like |
| |
Mtch1 |
mitochondrial carrier 1 |
| |
Gsk3b |
glycogen synthase kinase 3 beta |
| |
Fzd2 |
frizzled class receptor 2 |
| |
Taz |
tafazzin |
| |
Nrarp |
Notch-regulated ankyrin repeat protein |
| |
Zkscan14 |
zinc finger with KRAB and SCAN domains 14 |
| |
Raver1 |
ribonucleoprotein, PTB-binding 1 |
| |
Robo4 |
roundabout guidance receptor 4 |
| |
Fzd10 |
frizzled class receptor 10 |
| |
Csnk1g2 |
casein kinase 1, gamma 2 |
| |
Pdzd8 |
PDZ domain containing 8 |
| |
Ddb2 |
damage specific DNA binding protein 2 |
| |
Fgfrl1 |
fibroblast growth factor receptor-like 1 |
| |
Tmem132c |
transmembrane protein 132C |
| |
Zfp871 |
zinc finger protein 871 |
| |
Frat2 |
frequently rearranged in advanced T cell lymphomas 2 |
| |
Shc2 |
SHC (Src homology 2 domain containing) transforming protein 2 |
| |
Wnt9a |
wingless-type MMTV integration site family, member 9A |
| |
Taok1 |
TAO kinase 1 |
| |
Znrf3 |
zinc and ring finger 3 |
|
|
Symbol |
Function* |
| |
Akt1 |
AKT serine/threonine kinase 1 |
| |
Egfr |
epidermal growth factor receptor |
| |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
| |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
| |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
| |
Nras |
NRAS proto-oncogene, GTPase |
| |
Rb1 |
RB transcriptional corepressor 1 |
| |
Tp53 |
tumor protein p53 |
| |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
| |
Atf3 |
activating transcription factor 3 |
| |
Notch1 |
notch receptor 1 |
| |
Prkg2 |
protein kinase cGMP-dependent 2 |
| |
Axin2 |
axin 2 |
| |
Jag1 |
jagged canonical Notch ligand 1 |
| |
Jag2 |
jagged canonical Notch ligand 2 |
| |
Hes1 |
hes family bHLH transcription factor 1 |
| |
Ppp3r1 |
protein phosphatase 3, regulatory subunit B, alpha |
| |
Notch3 |
notch receptor 3 |
| |
Ccnd1 |
cyclin D1 |
| |
Map2k2 |
mitogen activated protein kinase kinase 2 |
| |
Adcy3 |
adenylate cyclase 3 |
| |
Fzd2 |
frizzled class receptor 2 |
| |
Mtpn |
myotrophin |
| |
Hes5 |
hes family bHLH transcription factor 5 |
| |
Axin1 |
axin 1 |
| |
Pdpk1 |
3-phosphoinositide dependent protein kinase-1 |
| |
Dll1 |
delta like canonical Notch ligand 1 |
| |
Gsk3b |
glycogen synthase kinase 3 beta |
| |
Ncoa3 |
nuclear receptor coactivator 3 |
| |
Sos2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
Cdk4 |
cyclin-dependent kinase 4 |
| |
Flt4 |
Fms related receptor tyrosine kinase 4 |
| |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
| |
Wnt7a |
Wnt family member 7A |
| |
Dusp1 |
dual specificity phosphatase 1 |
| |
Bak1 |
BCL2-antagonist/killer 1 |
| |
Mapk1 |
mitogen activated protein kinase 1 |
| |
Wnt11 |
Wnt family member 11 |
| |
Hey2 |
hes-related family bHLH transcription factor with YRPW motif 2 |
| |
Lef1 |
lymphoid enhancer binding factor 1 |
| |
Map2k1 |
mitogen activated protein kinase kinase 1 |
| |
Foxc2 |
forkhead box C2 |
| |
Nacc1 |
nucleus accumbens associated 1 |
| |
Ipmk |
inositol polyphosphate multikinase |
| |
Fzd6 |
frizzled class receptor 6 |
| |
Ephb3 |
Eph receptor B3 |
| |
Ankrd17 |
ankyrin repeat domain 17 |
| |
Ushbp1 |
USH1 protein network component harmonin binding protein 1 |
| |
Gatad2a |
GATA zinc finger domain containing 2A |
| |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
| |
E2f3 |
E2F transcription factor 3 |
| |
Hras |
HRas proto-oncogene, GTPase |
| |
Slc35g1 |
solute carrier family 35, member G1 |
| |
Raver1 |
ribonucleoprotein, PTB-binding 1 |
| |
Apc2 |
APC regulator of WNT signaling pathway 2 |
| |
Abhd17a |
abhydrolase domain containing 17A, depalmitoylase |
| |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
| |
Fbxo11 |
F-box protein 11 |
| |
Rhbdf1 |
rhomboid 5 homolog 1 |
| |
Dvl3 |
dishevelled segment polarity protein 3 |
| |
Tab2 |
TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| |
Dll4 |
delta like canonical Notch ligand 4 |
| |
Lrp6 |
LDL receptor related protein 6 |
| |
Heyl |
hes-related family bHLH transcription factor with YRPW motif-like |
| |
Casz1 |
castor zinc finger 1 |
| |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
| |
Ncoa1 |
nuclear receptor coactivator 1 |
| |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
| |
Wnt7b |
Wnt family member 7B |
| |
Wnt6 |
Wnt family member 6 |
| |
Wnt10a |
Wnt family member 10A |
| |
Fzd5 |
frizzled class receptor 5 |
| |
Dcakd |
dephospho-CoA kinase domain containing |
| |
Relt |
RELT, TNF receptor |
| |
Tcf7 |
transcription factor 7 |
| |
Fzd10 |
frizzled class receptor 10 |
| |
Fzd8 |
frizzled class receptor 8 |
| |
Pik3cd |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| |
Notch4 |
notch receptor 4 |
| |
Ier2 |
immediate early response 2 |
| |
Nrarp |
Notch-regulated ankyrin repeat protein |
| |
Wnt16 |
Wnt family member 16 |
| |
Frat2 |
FRAT regulator of WNT signaling pathway 2 |
| |
E2f2 |
E2F transcription factor 2 |
| |
Fzd7 |
frizzled class receptor 7 |
| |
LOC100363171 |
histone variant H2al2-like |
| |
Ankhd1 |
ankyrin repeat and KH domain containing 1 |
| |
Robo4 |
roundabout guidance receptor 4 |
| |
Frat1 |
FRAT regulator of WNT signaling pathway 1 |
|
|
|
|
Symbol |
Function* |
| |
TP53 |
tumor protein p53 |
| |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
| |
ESR1 |
estrogen receptor 1 |
| |
KRAS |
KRAS proto-oncogene, GTPase |
| |
CCND1 |
cyclin D1 |
| |
FGF2 |
fibroblast growth factor 2 |
| |
DUS1L |
dihydrouridine synthase 1 like |
| |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
| |
GSK3B |
glycogen synthase kinase 3 beta |
| |
LRP6 |
LDL receptor related protein 6 |
| |
PHF3 |
PHD finger protein 3 |
| |
NCOA3 |
nuclear receptor coactivator 3 |
| |
SHC2 |
SHC adaptor protein 2 |
| |
DLL1 |
delta like canonical Notch ligand 1 |
| |
DVL1 |
dishevelled segment polarity protein 1 |
| |
TNS1 |
tensin 1 |
| |
CRKL |
CRK like proto-oncogene, adaptor protein |
| |
FGFR1 |
fibroblast growth factor receptor 1 |
| |
ESR2 |
estrogen receptor 2 |
| |
GADD45G |
growth arrest and DNA damage inducible gamma |
| |
MIB2 |
MIB E3 ubiquitin protein ligase 2 |
| |
MAPK1 |
mitogen-activated protein kinase 1 |
| |
FRAT1 |
FRAT regulator of WNT signaling pathway 1 |
| |
AKT1 |
AKT serine/threonine kinase 1 |
| |
GADD45B |
growth arrest and DNA damage inducible beta |
| |
NOTCH3 |
notch receptor 3 |
| |
AXIN1 |
axin 1 |
| |
SOS2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
| |
JAG2 |
jagged canonical Notch ligand 2 |
| |
ST3GAL1 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| |
E2F3 |
E2F transcription factor 3 |
| |
ARAF |
A-Raf proto-oncogene, serine/threonine kinase |
| |
TCF7L1 |
transcription factor 7 like 1 |
| |
NUDT6 |
nudix hydrolase 6 |
| |
WNT16 |
Wnt family member 16 |
| |
MED1 |
mediator complex subunit 1 |
| |
RPS6KB2 |
ribosomal protein S6 kinase B2 |
| |
DDB2 |
damage specific DNA binding protein 2 |
| |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
| |
WNT10A |
Wnt family member 10A |
| |
LIMD1 |
LIM domain containing 1 |
| |
PTBP1 |
polypyrimidine tract binding protein 1 |
| |
SHC1 |
SHC adaptor protein 1 |
| |
PIK3R3 |
phosphoinositide-3-kinase regulatory subunit 3 |
| |
FZD4 |
frizzled class receptor 4 |
| |
KLF15 |
Kruppel like factor 15 |
| |
WNT10B |
Wnt family member 10B |
| |
WNT1 |
Wnt family member 1 |
| |
FLRT3 |
fibronectin leucine rich transmembrane protein 3 |
| |
FOSB |
FosB proto-oncogene, AP-1 transcription factor subunit |
| |
WNT4 |
Wnt family member 4 |
| |
TCF7L2 |
transcription factor 7 like 2 |
| |
KAT6A |
lysine acetyltransferase 6A |
| |
RAF1 |
Raf-1 proto-oncogene, serine/threonine kinase |
| |
ZFP36 |
ZFP36 ring finger protein |
| |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
| |
RALGAPB |
Ral GTPase activating protein non-catalytic subunit beta |
| |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| |
KANK2 |
KN motif and ankyrin repeat domains 2 |
| |
CDK4 |
cyclin dependent kinase 4 |
| |
MTMR1 |
myotubularin related protein 1 |
| |
FLNB |
filamin B |
| |
SOS1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
| |
ZNF445 |
zinc finger protein 445 |
| |
ZFHX3 |
zinc finger homeobox 3 |
| |
HIRIP3 |
HIRA interacting protein 3 |
| |
FLII |
FLII actin remodeling protein |
| |
FGF23 |
fibroblast growth factor 23 |
| |
SP1 |
Sp1 transcription factor |
| |
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
| |
RB1 |
RB transcriptional corepressor 1 |
| |
HSF1 |
heat shock transcription factor 1 |
| |
FRAT2 |
FRAT regulator of WNT signaling pathway 2 |
|