KEGG 01524 Platinum drug resistance
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa01524 Platinum drug resistance 18
hsa05200 Pathways in cancer 17
hsa05225 Hepatocellular carcinoma 10
hsa05208 Chemical carcinogenesis - reactive oxygen species 8
hsa04210 Apoptosis 7
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu01524 Platinum drug resistance 38
mmu05200 Pathways in cancer 36
mmu05225 Hepatocellular carcinoma 23
mmu05418 Fluid shear stress and atherosclerosis 20
mmu05207 Chemical carcinogenesis - receptor activation 19
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno01524 Platinum drug resistance 31
rno05200 Pathways in cancer 27
rno00980 Metabolism of xenobiotics by cytochrome P450 20
rno05207 Chemical carcinogenesis - receptor activation 20
rno05225 Hepatocellular carcinoma 20
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc01524 Platinum drug resistance 27
mcc05200 Pathways in cancer 25
mcc05225 Hepatocellular carcinoma 17
mcc05207 Chemical carcinogenesis - receptor activation 14
mcc04210 Apoptosis 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa01524 Platinum drug resistance 26
cfa05200 Pathways in cancer 23
cfa05225 Hepatocellular carcinoma 16
cfa05204 Chemical carcinogenesis - DNA adducts 16
cfa05207 Chemical carcinogenesis - receptor activation 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca01524 Platinum drug resistance 18
fca05200 Pathways in cancer 18
fca04210 Apoptosis 10
fca05417 Lipid and atherosclerosis 10
fca05207 Chemical carcinogenesis - receptor activation 10
Gene list in the network
Symbol Function*
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
FAS Fas cell surface death receptor
BAK1 BCL2 antagonist/killer 1
BAX BCL2 associated X, apoptosis regulator
DDB2 damage specific DNA binding protein 2
FDXR ferredoxin reductase
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2
GSTM3 glutathione S-transferase mu 3
GSTM4 glutathione S-transferase mu 4
GSTM5 glutathione S-transferase mu 5
MSH6 mutS homolog 6
MCM3 minichromosome maintenance complex component 3
MDM2 MDM2 proto-oncogene
MSH2 mutS homolog 2
PDPK1 3-phosphoinositide dependent protein kinase 1
POLH DNA polymerase eta
BBC3 BCL2 binding component 3
RPS27L ribosomal protein S27 like
TRIAP1 TP53 regulated inhibitor of apoptosis 1
KCTD5 potassium channel tetramerization domain containing 5
ZMAT3 zinc finger matrin-type 3
AEN apoptosis enhancing nuclease
Symbol Function*
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Apaf1 apoptotic peptidase activating factor 1
Birc3 baculoviral IAP repeat-containing 3
Birc2 baculoviral IAP repeat-containing 2
Birc5 baculoviral IAP repeat-containing 5
Bak1 BCL2-antagonist/killer 1
Bax BCL2-associated X protein
Bcl2 B cell leukemia/lymphoma 2
Cdk1 cyclin-dependent kinase 1
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21)
Cdkn2a cyclin dependent kinase inhibitor 2A
Cdkn2b cyclin dependent kinase inhibitor 2B
Ddt D-dopachrome tautomerase
Fas Fas (TNF receptor superfamily member 6)
Gsta2 glutathione S-transferase, alpha 2 (Yc2)
Gsta3 glutathione S-transferase, alpha 3
Gsta4 glutathione S-transferase, alpha 4
Gstm1 glutathione S-transferase, mu 1
Gstm2 glutathione S-transferase, mu 2
Gstm3 glutathione S-transferase, mu 3
Gstm4 glutathione S-transferase, mu 4
Gstm6 glutathione S-transferase, mu 6
Gstp1 glutathione S-transferase, pi 1
Gstt1 glutathione S-transferase, theta 1
Gstt2 glutathione S-transferase, theta 2
Gsto1 glutathione S-transferase omega 1
Mcm4 minichromosome maintenance complex component 4
Mdm2 transformed mouse 3T3 cell double minute 2
Msh2 mutS homolog 2
Msh6 mutS homolog 6
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Pdpk1 3-phosphoinositide dependent protein kinase 1
Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit
Top2a topoisomerase (DNA) II alpha
Top2b topoisomerase (DNA) II beta
Trp53 transformation related protein 53
Atrx ATRX, chromatin remodeler
Phlda3 pleckstrin homology like domain, family A, member 3
Mgst1 microsomal glutathione S-transferase 1
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1
Sqor sulfide quinone oxidoreductase
Ptgr1 prostaglandin reductase 1
Gstm7 glutathione S-transferase, mu 7
Raver1 ribonucleoprotein, PTB-binding 1
Ddias DNA damage-induced apoptosis suppressor
Gstt3 glutathione S-transferase, theta 3
Csnk1g2 casein kinase 1, gamma 2
Rasa2 RAS p21 protein activator 2
Bbc3 BCL2 binding component 3
Mgst2 microsomal glutathione S-transferase 2
Symbol Function*
Gsta1 glutathione S-transferase alpha 1
Gsta2 glutathione S-transferase alpha 2
Gstm1 glutathione S-transferase mu 1
Gstm2 glutathione S-transferase mu 2
Tp53 tumor protein p53
Atp7a ATPase copper transporting alpha
Gstt1 glutathione S-transferase theta 1
Abcc2 ATP binding cassette subfamily C member 2
Ephx1 epoxide hydrolase 1
Casp3 caspase 3
Akr7a3 aldo-keto reductase family 7 member A3
Ddt D-dopachrome tautomerase
Gstt2 glutathione S-transferase, theta 2
Aox1 aldehyde oxidase 1
Xiap X-linked inhibitor of apoptosis
Gstm5 glutathione S-transferase, mu 5
Apaf1 apoptotic peptidase activating factor 1
Msh2 mutS homolog 2
Gstm7 glutathione S-transferase, mu 7
Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35
Cdkn1a cyclin-dependent kinase inhibitor 1A
Bak1 BCL2-antagonist/killer 1
Nup107 nucleoporin 107
Mgst1 microsomal glutathione S-transferase 1
Slc17a3 solute carrier family 17 member 3
Mgst2 microsomal glutathione S-transferase 2
Raver1 ribonucleoprotein, PTB-binding 1
Atm ATM serine/threonine kinase
Gsta4 glutathione S-transferase alpha 4
Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit
Mdm2 MDM2 proto-oncogene
Mob1b MOB kinase activator 1B
Aen apoptosis enhancing nuclease
Setx senataxin
Gsta5 glutathione S-transferase alpha 5
Gsta3 glutathione S-transferase alpha 3
Gstt3 glutathione S-transferase, theta 3
Msh3 mutS homolog 3
Gstm6 glutathione S-transferase, mu 6
Gstm4 glutathione S-transferase mu 4
Gsta6 glutathione S-transferase alpha 6
Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase
Msh6 mutS homolog 6
Rfwd3 ring finger and WD repeat domain 3
Symbol Function*
FAS Fas cell surface death receptor
JAK1 Janus kinase 1
TOP2B DNA topoisomerase II beta
SPPL2A signal peptide peptidase like 2A
APAF1 apoptotic peptidase activating factor 1
CSRNP1 cysteine and serine rich nuclear protein 1
MGST2 microsomal glutathione S-transferase 2
XIAP X-linked inhibitor of apoptosis
MAPK1 mitogen-activated protein kinase 1
GSTM4 glutathione S-transferase mu 4
GSTM2 glutathione S-transferase mu 2
TOP2A DNA topoisomerase II alpha
CCNB2 cyclin B2
BIRC2 baculoviral IAP repeat containing 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
B4GALT2 beta-1,4-galactosyltransferase 2
RAP2C RAP2C, member of RAS oncogene family
FOXM1 forkhead box M1
ACTL6A actin like 6A
MAPK3 mitogen-activated protein kinase 3
GSTA1 glutathione S-transferase alpha 1
LOC709417 glutathione S-transferase A5
GSTA3 glutathione S-transferase alpha 3
BIRC5 baculoviral IAP repeat containing 5
PPP3CA protein phosphatase 3 catalytic subunit alpha
LOC709988 cyclin-dependent kinase inhibitor 2A
MAP3K5 mitogen-activated protein kinase kinase kinase 5
ZBTB41 zinc finger and BTB domain containing 41
DDB2 damage specific DNA binding protein 2
MSH6 mutS homolog 6
GSTO1 glutathione S-transferase omega 1
BAD BCL2 associated agonist of cell death
MSH2 mutS homolog 2
BAX BCL2 associated X, apoptosis regulator
CDKN1A cyclin dependent kinase inhibitor 1A
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
AP1S1 adaptor related protein complex 1 subunit sigma 1
GSTM5 glutathione S-transferase mu 5
ATM ATM serine/threonine kinase
Symbol Function*
BAX BCL2 associated X, apoptosis regulator
MDM2 MDM2 proto-oncogene
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
ATP7A ATPase copper transporting alpha
BIRC5 baculoviral IAP repeat containing 5
XIAP X-linked inhibitor of apoptosis
CAND1 cullin associated and neddylation dissociated 1
CNOT2 CCR4-NOT transcription complex subunit 2
MSH6 mutS homolog 6
PTGR1 prostaglandin reductase 1
LOC474938 glutathione S-transferase A2
GSTA4 glutathione S-transferase alpha 4
GSTP1 glutathione S-transferase pi 1
LOC476006 glutathione S-transferase P-like
MLH1 mutL homolog 1
WDR48 WD repeat domain 48
TOP2B DNA topoisomerase II beta
LOC477556 glutathione S-transferase theta-1
LOC477558 glutathione S-transferase theta-1
MGST1 microsomal glutathione S-transferase 1
GSTO1 glutathione S-transferase omega 1
LOC479911 glutathione S-transferase Mu 3
LOC479912 glutathione S-transferase Mu 1
DLGAP5 DLG associated protein 5
TOP2A DNA topoisomerase II alpha
LOC486404 glutathione S-transferase theta-4
MSH2 mutS homolog 2
MGST3 microsomal glutathione S-transferase 3
LOC610304 glutathione S-transferase A4-like
BBC3 BCL2 binding component 3
GSTT2B glutathione S-transferase theta 2B
DDT D-dopachrome tautomerase
LOC100856518 glutathione S-transferase theta-3-like
TXNDC17 thioredoxin domain containing 17
Symbol Function*
BAX BCL2 associated X, apoptosis regulator
FAS Fas cell surface death receptor
CASP3 caspase 3
BCL2 BCL2 apoptosis regulator
CASP9 caspase 9
AKT2 AKT serine/threonine kinase 2
BID BH3 interacting domain death agonist
CHMP4A charged multivesicular body protein 4A
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MAP3K5 mitogen-activated protein kinase kinase kinase 5
LOC101083370 glutathione S-transferase theta-1
LOC101083623 glutathione S-transferase theta-4-like
GSTA4 glutathione S-transferase alpha 4
ABCC10 ATP binding cassette subfamily C member 10
MAPK1 mitogen-activated protein kinase 1
ICAM1 intercellular adhesion molecule 1
STAT5A signal transducer and activator of transcription 5A
LOC101092550 glutathione S-transferase theta-1-like
ZRANB3 zinc finger RANBP2-type containing 3
RAB5C RAB5C, member RAS oncogene family
FAM241B family with sequence similarity 241 member B
LOC101096317 glutathione S-transferase A2
ARL5A ADP ribosylation factor like GTPase 5A
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
LOC111560471 glutathione S-transferase A2-like


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