KEGG 04012 ErbB signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) gga(Chicken) dre(Zebrafish) cel(Nematoda) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04012 ErbB signaling pathway 19
hsa04010 MAPK signaling pathway 14
hsa05200 Pathways in cancer 14
hsa04935 Growth hormone synthesis, secretion and action 12
hsa05161 Hepatitis B 12
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04012 ErbB signaling pathway 25
mmu04935 Growth hormone synthesis, secretion and action 18
mmu05200 Pathways in cancer 18
mmu04010 MAPK signaling pathway 16
mmu05161 Hepatitis B 16
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04012 ErbB signaling pathway 25
rno05200 Pathways in cancer 21
rno04722 Neurotrophin signaling pathway 18
rno04010 MAPK signaling pathway 17
rno04910 Insulin signaling pathway 17
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04012 ErbB signaling pathway 29
gga04510 Focal adhesion 19
gga04010 MAPK signaling pathway 16
gga04910 Insulin signaling pathway 12
gga04370 VEGF signaling pathway 12
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
dre04012 ErbB signaling pathway 37
dre04510 Focal adhesion 19
dre04010 MAPK signaling pathway 18
dre04910 Insulin signaling pathway 16
dre04912 GnRH signaling pathway 16
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cel04012 ErbB signaling pathway 14
cel04010 MAPK signaling pathway 10
cel04068 FoxO signaling pathway 6
cel04150 mTOR signaling pathway 5
cel04361 Axon regeneration 4
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04012 ErbB signaling pathway 33
mcc05200 Pathways in cancer 24
mcc04510 Focal adhesion 19
mcc04722 Neurotrophin signaling pathway 18
mcc05210 Colorectal cancer 18
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04012 ErbB signaling pathway 21
cfa05200 Pathways in cancer 16
cfa04010 MAPK signaling pathway 15
cfa04151 PI3K-Akt signaling pathway 13
cfa04935 Growth hormone synthesis, secretion and action 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04012 ErbB signaling pathway 21
fca05200 Pathways in cancer 19
fca04935 Growth hormone synthesis, secretion and action 16
fca05161 Hepatitis B 15
fca05205 Proteoglycans in cancer 15
Gene list in the network
Symbol Function*
AKT2 AKT serine/threonine kinase 2
ARAF A-Raf proto-oncogene, serine/threonine kinase
AREG amphiregulin
ATF3 activating transcription factor 3
CRK CRK proto-oncogene, adaptor protein
CRKL CRK like proto-oncogene, adaptor protein
HBEGF heparin binding EGF like growth factor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EREG epiregulin
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MAPK1 mitogen-activated protein kinase 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
STAT3 signal transducer and activator of transcription 3
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
USF2 upstream transcription factor 2, c-fos interacting
PAK4 p21 (RAC1) activated kinase 4
ATP11B ATPase phospholipid transporting 11B (putative)
ALKBH5 alkB homolog 5, RNA demethylase
SAMD4B sterile alpha motif domain containing 4B
EPGN epithelial mitogen
LOC105377276 uncharacterized LOC105377276
Symbol Function*
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Areg amphiregulin
Btc betacellulin, epidermal growth factor family member
Camk2g calcium/calmodulin-dependent protein kinase II gamma
Coro1a coronin, actin binding protein 1A
Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like
Erbb3 erb-b2 receptor tyrosine kinase 3
Ereg epiregulin
Fosl1 fos-like antigen 1
Grb2 growth factor receptor bound protein 2
Hras Harvey rat sarcoma virus oncogene
Mbd3 methyl-CpG binding domain protein 3
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Prkca protein kinase C, alpha
Prkcb protein kinase C, beta
Atxn1 ataxin 1
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Sox10 SRY (sex determining region Y)-box 10
Stat3 signal transducer and activator of transcription 3
Stat5a signal transducer and activator of transcription 5A
Stat5b signal transducer and activator of transcription 5B
Map2k2 mitogen-activated protein kinase kinase 2
Map2k4 mitogen-activated protein kinase kinase 4
Map2k7 mitogen-activated protein kinase kinase 7
Mapk9 mitogen-activated protein kinase 9
Mtch1 mitochondrial carrier 1
Gsk3b glycogen synthase kinase 3 beta
Rnf14 ring finger protein 14
Rps6kb2 ribosomal protein S6 kinase, polypeptide 2
Csnk1g2 casein kinase 1, gamma 2
Cggbp1 CGG triplet repeat binding protein 1
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Pak2 p21 (RAC1) activated kinase 2
Leng8 leukocyte receptor cluster (LRC) member 8
Shc4 SHC (Src homology 2 domain containing) family, member 4
Symbol Function*
Jun Jun proto-oncogene, AP-1 transcription factor subunit
Nras NRAS proto-oncogene, GTPase
Tgfa transforming growth factor alpha
Stat5a signal transducer and activator of transcription 5A
Stat5b signal transducer and activator of transcription 5B
Akt2 AKT serine/threonine kinase 2
Atf3 activating transcription factor 3
Hbegf heparin-binding EGF-like growth factor
Gnai3 G protein subunit alpha i3
Pak2 p21 (RAC1) activated kinase 2
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Mapk9 mitogen-activated protein kinase 9
Crk CRK proto-oncogene, adaptor protein
Map2k2 mitogen activated protein kinase kinase 2
Slc30a1 solute carrier family 30 member 1
Mtpn myotrophin
Pdpk1 3-phosphoinositide dependent protein kinase-1
Gsk3b glycogen synthase kinase 3 beta
Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta
Braf B-Raf proto-oncogene, serine/threonine kinase
Mapk1 mitogen activated protein kinase 1
Septin2 septin 2
Map2k1 mitogen activated protein kinase kinase 1
Serinc5 serine incorporator 5
Cblb Cbl proto-oncogene B
Camk2g calcium/calmodulin-dependent protein kinase II gamma
Ipmk inositol polyphosphate multikinase
Map2k4 mitogen activated protein kinase kinase 4
Crkl CRK like proto-oncogene, adaptor protein
Hras HRas proto-oncogene, GTPase
Pknox1 PBX/knotted 1 homeobox 1
Zbtb7b zinc finger and BTB domain containing 7B
Abhd17a abhydrolase domain containing 17A, depalmitoylase
Fbxo11 F-box protein 11
Ash1l ASH1 like histone lysine methyltransferase
Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1
Gab1 GRB2-associated binding protein 1
Hdac4 histone deacetylase 4
Cbl Cbl proto-oncogene
Symbol Function*
GRB2 growth factor receptor bound protein 2
USP7 ubiquitin specific peptidase 7
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
STAT5A signal transducer and activator of transcription 5A
CDC42 cell division cycle 42
CSNK1A1 casein kinase 1 alpha 1
AKT1 AKT serine/threonine kinase 1
PTK2 protein tyrosine kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
EREG epiregulin
MAP2K1 mitogen-activated protein kinase kinase 1
SYNGR3 synaptogyrin 3
PRKCB protein kinase C beta
CRKL CRK like proto-oncogene, adaptor protein
MAP2K4 mitogen-activated protein kinase kinase 4
PRKCA protein kinase C alpha
GSK3A glycogen synthase kinase 3 alpha
NCK1 NCK adaptor protein 1
PLCG1 phospholipase C gamma 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
RASSF5 Ras association domain family member 5
ANKRD28 ankyrin repeat domain 28
CAMK2D calcium/calmodulin dependent protein kinase II delta
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
PAK2 p21 (RAC1) activated kinase 2
RPRD2 regulation of nuclear pre-mRNA domain containing 2
EIF4G3 eukaryotic translation initiation factor 4 gamma 3
ERBB2 erb-b2 receptor tyrosine kinase 2
AREG amphiregulin
RPS6KB2 ribosomal protein S6 kinase B2
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
ERBB3 erb-b2 receptor tyrosine kinase 3
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
PAK4 p21 (RAC1) activated kinase 4
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
LOC776273 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1-like
ANKRD13B ankyrin repeat domain 13B
CBX6 chromobox 6
CRK CRK proto-oncogene, adaptor protein
LOC121108647 inositol polyphosphate phosphatase like 1
Symbol Function*
ptpn1 protein tyrosine phosphatase non-receptor type 1
nras NRAS proto-oncogene, GTPase
myca MYC proto-oncogene, bHLH transcription factor a
badb BCL2 associated agonist of cell death b
mapk8b mitogen-activated protein kinase 8b
ptk2ab protein tyrosine kinase 2ab
atp6v0b ATPase H+ transporting V0 subunit b
shc1 SHC (Src homology 2 domain containing) transforming protein 1
gnai2b guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
mapk1 mitogen-activated protein kinase 1
scrib scribble planar cell polarity protein
stat5a signal transducer and activator of transcription 5a
plcg1 phospholipase C, gamma 1
erbb3a erb-b2 receptor tyrosine kinase 3a
ptk2aa protein tyrosine kinase 2aa
erbb2 erb-b2 receptor tyrosine kinase 2
mycb MYC proto-oncogene, bHLH transcription factor b
prkcbb protein kinase C, beta b
nck2a NCK adaptor protein 2a
mapk3 mitogen-activated protein kinase 3
pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
grb2b growth factor receptor-bound protein 2b
hbegfb heparin-binding EGF-like growth factor b
pak4 p21 protein (Cdc42/Rac)-activated kinase 4
camk2d1 calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
gipc1 GIPC PDZ domain containing family, member 1
cbl Cbl proto-oncogene, E3 ubiquitin protein ligase
neurl4 neuralized E3 ubiquitin protein ligase 4
cblb Cbl proto-oncogene B, E3 ubiquitin protein ligase
crkl v-crk avian sarcoma virus CT10 oncogene homolog-like
kmt2a lysine (K)-specific methyltransferase 2A
raf1b Raf-1 proto-oncogene, serine/threonine kinase b
osbpl2a oxysterol binding protein-like 2a
dlgap2a discs, large (Drosophila) homolog-associated protein 2a
rc3h1b ring finger and CCCH-type domains 1b
akt3a v-akt murine thymoma viral oncogene homolog 3a
map2k7 mitogen-activated protein kinase kinase 7
pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
camk2b1 calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
rps6kc1 ribosomal protein S6 kinase polypeptide 1
snx27a sorting nexin 27a
map2k4b mitogen-activated protein kinase kinase 4b
abl2 c-abl oncogene 2, non-receptor tyrosine kinase
camk2g1 calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
camk2b calcium/calmodulin dependent protein kinase II beta
lrch4 leucine-rich repeats and calponin homology (CH) domain containing 4
mark2b MAP/microtubule affinity-regulating kinase 2b
prkcba protein kinase C, beta a
erbb4a erb-b2 receptor tyrosine kinase 4a
sgpl1 sphingosine-1-phosphate lyase 1
mapk9 mitogen-activated protein kinase 9
cpne8 copine VIII
LOC100536197 serine/threonine-protein kinase PAK 6
Symbol Function*
kin-32 Inactive tyrosine-protein kinase kin-32
goa-1 Guanine nucleotide-binding protein G(o) subunit alpha
cdc-42 Cell division control protein 42 homolog
let-23 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase let-23
plc-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3
mpk-1 Mitogen-activated protein kinase mpk-1
lin-45 Raf homolog serine/threonine-protein kinase
kin-4 Non-specific serine/threonine protein kinase
let-60 Ras protein let-60
akt-1 Serine/threonine-protein kinase akt-1
sli-1 E3 ubiquitin-protein ligase CBL
nck-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
dnj-14 J domain-containing protein
sek-3 Protein kinase domain-containing protein
pak-1 Serine/threonine-protein kinase pak-1
mek-1 Dual specificity mitogen-activated protein kinase kinase mek-1
sem-5 Sex muscle abnormal protein 5
abl-1 Tyrosine-protein kinase;Tyrosine-protein kinase abl-1
madd-3 Protein kinase domain-containing protein;putative dual specificity protein kinase madd-3
Symbol Function*
STAT5A signal transducer and activator of transcription 5A
BRAF B-Raf proto-oncogene, serine/threonine kinase
NPEPPS aminopeptidase puromycin sensitive
ASXL2 ASXL transcriptional regulator 2
HBEGF heparin binding EGF like growth factor
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
PCSK2 proprotein convertase subtilisin/kexin type 2
CRKL CRK like proto-oncogene, adaptor protein
STUB1 STIP1 homology and U-box containing protein 1
CNOT6L CCR4-NOT transcription complex subunit 6 like
EGF epidermal growth factor
HRAS HRas proto-oncogene, GTPase
NRG3 neuregulin 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STXBP5 syntaxin binding protein 5
AREG amphiregulin
EREG epiregulin
CAMK2D calcium/calmodulin dependent protein kinase II delta
DUSP1 dual specificity phosphatase 1
CBLB Cbl proto-oncogene B
B4GALT2 beta-1,4-galactosyltransferase 2
CBL Cbl proto-oncogene
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
CAMK2G calcium/calmodulin dependent protein kinase II gamma
PAK3 p21 (RAC1) activated kinase 3
TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3
STAT5B signal transducer and activator of transcription 5B
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MAP2K1 mitogen-activated protein kinase kinase 1
CAMK2A calcium/calmodulin dependent protein kinase II alpha
MAPK8 mitogen-activated protein kinase 8
GSK3B glycogen synthase kinase 3 beta
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
AKT3 AKT serine/threonine kinase 3
MAPK9 mitogen-activated protein kinase 9
JUN Jun proto-oncogene, AP-1 transcription factor subunit
PTGS2 prostaglandin-endoperoxide synthase 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ITGB3 integrin subunit beta 3
KIAA2026 KIAA2026
BAD BCL2 associated agonist of cell death
MAP2K4 mitogen-activated protein kinase kinase 4
CHMP6 charged multivesicular body protein 6
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
PAK5 p21 (RAC1) activated kinase 5
RPS6KB2 ribosomal protein S6 kinase B2
MAP2K2 mitogen-activated protein kinase kinase 2
NCS1 neuronal calcium sensor 1
Symbol Function*
NRAS NRAS proto-oncogene, GTPase
ERBB2 erb-b2 receptor tyrosine kinase 2
PTGS2 prostaglandin-endoperoxide synthase 2
AKT3 AKT serine/threonine kinase 3
CDKN1A cyclin dependent kinase inhibitor 1A
AREG amphiregulin
DDA1 DET1 and DDB1 associated 1
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
GSK3B glycogen synthase kinase 3 beta
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
RASAL2 RAS protein activator like 2
ERBB3 erb-b2 receptor tyrosine kinase 3
NCK2 NCK adaptor protein 2
GRB2 growth factor receptor bound protein 2
FKBP8 FKBP prolyl isomerase 8
SNAP29 synaptosome associated protein 29
MAPKAPK2 MAPK activated protein kinase 2
AKT1 AKT serine/threonine kinase 1
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
CRKL CRK like proto-oncogene, adaptor protein
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
MAP2K2 mitogen-activated protein kinase kinase 2
EREG epiregulin
PAK2 p21 (RAC1) activated kinase 2
CRK CRK proto-oncogene, adaptor protein
MYH14 myosin heavy chain 14
OSBPL11 oxysterol binding protein like 11
Symbol Function*
KRAS KRAS proto-oncogene, GTPase
AKT2 AKT serine/threonine kinase 2
MAP2K1 mitogen-activated protein kinase kinase 1
GSK3B glycogen synthase kinase 3 beta
MAP2K3 mitogen-activated protein kinase kinase 3
PHF3 PHD finger protein 3
CAMK2A calcium/calmodulin dependent protein kinase II alpha
CRKL CRK like proto-oncogene, adaptor protein
MAPK1 mitogen-activated protein kinase 1
AKT1 AKT serine/threonine kinase 1
EP300 E1A binding protein p300
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2
MTMR3 myotubularin related protein 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
STAT5B signal transducer and activator of transcription 5B
STAT5A signal transducer and activator of transcription 5A
LIMD1 LIM domain containing 1
EREG epiregulin
HBEGF heparin binding EGF like growth factor
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
LOC101096508 E3 ubiquitin-protein ligase CBL
RALGAPB Ral GTPase activating protein non-catalytic subunit beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
MTMR1 myotubularin related protein 1
PAK4 p21 (RAC1) activated kinase 4
CAMK2B calcium/calmodulin dependent protein kinase II beta
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
FLII FLII actin remodeling protein
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
MAP2K2 mitogen-activated protein kinase kinase 2
HSF1 heat shock transcription factor 1
LOC109492199 uncharacterized LOC109492199


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