COXPRESdb : GeneID search result

[←][→] cfa RAF1 Gene

functional annotation

Function

Raf-1 proto-oncogene, serine/threonine kinase

GO BP

GO CC

GO MF

KEGG

cfa01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (84 genes)

cfa01522 [list] [network] Endocrine resistance (94 genes)

cfa04010 [list] [network] MAPK signaling pathway (288 genes)

cfa04012 [list] [network] ErbB signaling pathway (83 genes)

cfa04014 [list] [network] Ras signaling pathway (229 genes)

cfa04015 [list] [network] Rap1 signaling pathway (213 genes)

cfa04022 [list] [network] cGMP-PKG signaling pathway (165 genes)

cfa04024 [list] [network] cAMP signaling pathway (215 genes)

cfa04062 [list] [network] Chemokine signaling pathway (180 genes)

cfa04068 [list] [network] FoxO signaling pathway (127 genes)

cfa04071 [list] [network] Sphingolipid signaling pathway (121 genes)

cfa04072 [list] [network] Phospholipase D signaling pathway (150 genes)

cfa04140 [list] [network] Autophagy - animal (139 genes)

cfa04150 [list] [network] mTOR signaling pathway (161 genes)

cfa04151 [list] [network] PI3K-Akt signaling pathway (359 genes)

cfa04210 [list] [network] Apoptosis (134 genes)

cfa04218 [list] [network] Cellular senescence (158 genes)

cfa04270 [list] [network] Vascular smooth muscle contraction (135 genes)

cfa04360 [list] [network] Axon guidance (182 genes)

cfa04370 [list] [network] VEGF signaling pathway (58 genes)

cfa04371 [list] [network] Apelin signaling pathway (143 genes)

cfa04510 [list] [network] Focal adhesion (201 genes)

cfa04540 [list] [network] Gap junction (88 genes)

cfa04550 [list] [network] Signaling pathways regulating pluripotency of stem cells (143 genes)

cfa04613 [list] [network] Neutrophil extracellular trap formation (181 genes)

cfa04625 [list] [network] C-type lectin receptor signaling pathway (99 genes)

cfa04630 [list] [network] JAK-STAT signaling pathway (156 genes)

cfa04650 [list] [network] Natural killer cell mediated cytotoxicity (99 genes)

cfa04660 [list] [network] T cell receptor signaling pathway (102 genes)

cfa04662 [list] [network] B cell receptor signaling pathway (67 genes)

cfa04664 [list] [network] Fc epsilon RI signaling pathway (66 genes)

cfa04666 [list] [network] Fc gamma R-mediated phagocytosis (96 genes)

cfa04720 [list] [network] Long-term potentiation (65 genes)

cfa04722 [list] [network] Neurotrophin signaling pathway (118 genes)

cfa04726 [list] [network] Serotonergic synapse (113 genes)

cfa04730 [list] [network] Long-term depression (59 genes)

cfa04810 [list] [network] Regulation of actin cytoskeleton (229 genes)

cfa04910 [list] [network] Insulin signaling pathway (140 genes)

cfa04912 [list] [network] GnRH signaling pathway (89 genes)

cfa04914 [list] [network] Progesterone-mediated oocyte maturation (95 genes)

cfa04915 [list] [network] Estrogen signaling pathway (138 genes)

cfa04916 [list] [network] Melanogenesis (100 genes)

cfa04917 [list] [network] Prolactin signaling pathway (69 genes)

cfa04919 [list] [network] Thyroid hormone signaling pathway (118 genes)

cfa04921 [list] [network] Oxytocin signaling pathway (150 genes)

cfa04926 [list] [network] Relaxin signaling pathway (130 genes)

cfa04928 [list] [network] Parathyroid hormone synthesis, secretion and action (106 genes)

cfa04929 [list] [network] GnRH secretion (63 genes)

cfa04935 [list] [network] Growth hormone synthesis, secretion and action (114 genes)

cfa05010 [list] [network] Alzheimer disease (432 genes)

cfa05022 [list] [network] Pathways of neurodegeneration - multiple diseases (505 genes)

cfa05034 [list] [network] Alcoholism (188 genes)

cfa05132 [list] [network] Salmonella infection (268 genes)

cfa05152 [list] [network] Tuberculosis (164 genes)

cfa05160 [list] [network] Hepatitis C (158 genes)

cfa05161 [list] [network] Hepatitis B (160 genes)

cfa05163 [list] [network] Human cytomegalovirus infection (219 genes)

cfa05164 [list] [network] Influenza A (158 genes)

cfa05165 [list] [network] Human papillomavirus infection (329 genes)

cfa05167 [list] [network] Kaposi sarcoma-associated herpesvirus infection (187 genes)

cfa05170 [list] [network] Human immunodeficiency virus 1 infection (208 genes)

cfa05200 [list] [network] Pathways in cancer (537 genes)

cfa05205 [list] [network] Proteoglycans in cancer (206 genes)

cfa05206 [list] [network] MicroRNAs in cancer (276 genes)

cfa05207 [list] [network] Chemical carcinogenesis - receptor activation (197 genes)

cfa05208 [list] [network] Chemical carcinogenesis - reactive oxygen species (238 genes)

cfa05210 [list] [network] Colorectal cancer (88 genes)

cfa05211 [list] [network] Renal cell carcinoma (71 genes)

cfa05212 [list] [network] Pancreatic cancer (78 genes)

cfa05213 [list] [network] Endometrial cancer (58 genes)

cfa05214 [list] [network] Glioma (74 genes)

cfa05215 [list] [network] Prostate cancer (99 genes)

cfa05218 [list] [network] Melanoma (73 genes)

cfa05219 [list] [network] Bladder cancer (41 genes)

cfa05220 [list] [network] Chronic myeloid leukemia (74 genes)

cfa05221 [list] [network] Acute myeloid leukemia (65 genes)

cfa05223 [list] [network] Non-small cell lung cancer (71 genes)

cfa05224 [list] [network] Breast cancer (145 genes)

cfa05225 [list] [network] Hepatocellular carcinoma (165 genes)

cfa05226 [list] [network] Gastric cancer (146 genes)

cfa05230 [list] [network] Central carbon metabolism in cancer (73 genes)

cfa05231 [list] [network] Choline metabolism in cancer (96 genes)

cfa05235 [list] [network] PD-L1 expression and PD-1 checkpoint pathway in cancer (87 genes)

Protein

XP_005632198.1 XP_022262065.1 XP_022262066.1 XP_038282819.1 XP_038282820.1 XP_038282821.1 XP_038282822.1 XP_038282823.1 XP_038311911.1 XP_859234.1

BLAST

XP_005632198.1 XP_022262065.1 XP_022262066.1 XP_038282819.1 XP_038282820.1 XP_038282821.1 XP_038282822.1 XP_038282823.1 XP_038311911.1 XP_859234.1

Orthologous

[Ortholog page] ARAF (hsa) RAF1 (hsa) Araf (mmu) Raf1 (rno) raf1a (dre) Raf (dme) Araf (rno) Raf1 (mmu) lin-45 (cel) RAF1 (gga) araf (dre) ARAF (cfa) raf1b (dre) RAF1 (mcc) ARAF (mcc) itt1 (spo) ARAF (fca) RAF1 (fca)

Subcellular
localization
wolf

nucl 4, cyto_nucl 4, cyto 3, mito 1, cysk 1, golg 1	(predict for XP_005632198.1)
nucl 4, cyto_nucl 4, cyto 3, mito 1, cysk 1, golg 1	(predict for XP_022262065.1)
mito 7, nucl 2, cyto 1	(predict for XP_022262066.1)
nucl 4, cyto_nucl 4, cyto 3, mito 1, cysk 1, golg 1	(predict for XP_038282819.1)
nucl 4, cyto_nucl 4, cyto 3, mito 1, cysk 1, golg 1	(predict for XP_038282820.1)
nucl 4, cyto_nucl 4, cyto 3, mito 1, cysk 1, golg 1	(predict for XP_038282821.1)
mito 7, nucl 2, cyto 1	(predict for XP_038282822.1)
mito 7, nucl 2, cyto 1	(predict for XP_038282823.1)
mito 7, nucl 2, cyto 1	(predict for XP_038311911.1)
nucl 4, cyto_nucl 4, cyto 3, mito 1, cysk 1, golg 1	(predict for XP_859234.1)

Gene coexpression

Network^*for
coexpressed
genes

[Cytoscape]

KEGG^* ID	Title	#genes	Link to the KEGG^* map (Multiple genes)
cfa04210	Apoptosis	2
cfa04010	MAPK signaling pathway	2
cfa04722	Neurotrophin signaling pathway	2
cfa04912	GnRH signaling pathway	2
cfa05132	Salmonella infection	2

Genes directly connected with RAF1 on the network
coex z^*	Locus	Function^*	Coexpression detail	Entrez Gene ID^*
9.0	MKRN2	makorin ring finger protein 2	[detail]	476531
6.6	TPRA1	transmembrane protein adipocyte associated 1	[detail]	484621
6.1	LOC111091236	uncharacterized LOC111091236	[detail]	111091236
5.4	SUN2	Sad1 and UNC84 domain containing 2	[detail]	481250
5.3	PLEKHM1	pleckstrin homology and RUN domain containing M1	[detail]	119873243

Coexpressed
gene list

[Coexpressed gene list for RAF1]

Gene expression

All samples

[Expression pattern for all samples]

Tissue specificity^*

Link to other DBs
Entrez Gene ID	484648
Refseq ID (protein)	XP_005632198.1
	XP_022262065.1
	XP_022262066.1
	XP_038282819.1
	XP_038282820.1
	XP_038282821.1
	XP_038282822.1
	XP_038282823.1
	XP_038311911.1
	XP_859234.1

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