| functional annotation |
| Function |
mitogen-activated protein kinase kinase 1 |
|
| GO BP |
|
GO:0006468 [list] [network] protein phosphorylation
|
(744 genes)
|
IEA
|
 |
|
GO:0016310 [list] [network] phosphorylation
|
(977 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004708 [list] [network] MAP kinase kinase activity
|
(15 genes)
|
IBA
|
|
|
GO:0004674 [list] [network] protein serine/threonine kinase activity
|
(548 genes)
|
IEA
|
|
|
GO:0004672 [list] [network] protein kinase activity
|
(756 genes)
|
IEA
|
|
|
GO:0016301 [list] [network] kinase activity
|
(989 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1578 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2320 genes)
|
IEA
|
|
|
GO:0016740 [list] [network] transferase activity
|
(2575 genes)
|
IEA
|
|
|
| KEGG |
dre04010 [list] [network] MAPK signaling pathway (409 genes) |
 |
| dre04012 [list] [network] ErbB signaling pathway (110 genes) |
|
| dre04068 [list] [network] FoxO signaling pathway (181 genes) |
|
| dre04114 [list] [network] Oocyte meiosis (151 genes) |
|
| dre04140 [list] [network] Autophagy - animal (200 genes) |
|
| dre04150 [list] [network] mTOR signaling pathway (206 genes) |
|
| dre04210 [list] [network] Apoptosis (201 genes) |
|
| dre04218 [list] [network] Cellular senescence (200 genes) |
|
| dre04270 [list] [network] Vascular smooth muscle contraction (177 genes) |
|
| dre04370 [list] [network] VEGF signaling pathway (81 genes) |
|
| dre04371 [list] [network] Apelin signaling pathway (193 genes) |
|
| dre04510 [list] [network] Focal adhesion (278 genes) |
|
| dre04540 [list] [network] Gap junction (132 genes) |
|
| dre04620 [list] [network] Toll-like receptor signaling pathway (106 genes) |
|
| dre04810 [list] [network] Regulation of actin cytoskeleton (308 genes) |
|
| dre04910 [list] [network] Insulin signaling pathway (180 genes) |
|
| dre04912 [list] [network] GnRH signaling pathway (132 genes) |
|
| dre04914 [list] [network] Progesterone-mediated oocyte maturation (112 genes) |
|
| dre04916 [list] [network] Melanogenesis (147 genes) |
|
| dre05132 [list] [network] Salmonella infection (332 genes) |
|
| Protein |
NP_998584.2
|
| BLAST |
NP_998584.2
|
| Orthologous |
[Ortholog page]
MAP2K1 (hsa)
MAP2K2 (hsa)
Map2k1 (mmu)
Map2k2 (mmu)
Dsor1 (dme)
Map2k2 (rno)
Map2k1 (rno)
mek-2 (cel)
MAP2K2 (gga)
MAP2K1 (gga)
MAP2K1 (cfa)
map2k2a (dre)
MAP2K2 (cfa)
MAP2K1 (mcc)
MAP2K2 (mcc)
PBS2 (sce)
pab2 (spo)
map2k2b (dre)
MAP2K1 (fca)
MAP2K2 (fca)
|
Subcellular
localization
wolf |
|
cyto 6,
cyto_nucl 5,
nucl 4
|
(predict for NP_998584.2)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| dre04371 |
Apelin signaling pathway |
4 |
 |
| dre04114 |
Oocyte meiosis |
3 |
 |
| dre04218 |
Cellular senescence |
3 |
 |
| dre04261 |
Adrenergic signaling in cardiomyocytes |
3 |
 |
| dre04270 |
Vascular smooth muscle contraction |
3 |
 |
Genes directly connected with map2k1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 4.8 |
atp1b3b |
ATPase Na+/K+ transporting subunit beta 3b |
[detail] |
64272 |
| 4.7 |
tspan7b |
tetraspanin 7b |
[detail] |
449539 |
| 4.6 |
sgcb |
sarcoglycan, beta (dystrophin-associated glycoprotein) |
[detail] |
559788 |
|
Coexpressed
gene list |
[Coexpressed gene list for map2k1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
map2k1 Gene
