| functional annotation |
| Function |
inositol 1,4,5-trisphosphate receptor, type 2 |
|
| GO BP |
|
GO:0051209 [list] [network] release of sequestered calcium ion into cytosol
|
(16 genes)
|
IBA
|
 |
|
GO:0070588 [list] [network] calcium ion transmembrane transport
|
(124 genes)
|
IEA
|
 |
|
GO:0006816 [list] [network] calcium ion transport
|
(146 genes)
|
IEA
|
 |
|
GO:0006811 [list] [network] ion transport
|
(915 genes)
|
IEA
|
 |
|
| GO CC |
|
GO:0030667 [list] [network] secretory granule membrane
|
(12 genes)
|
IBA
|
 |
|
GO:0016529 [list] [network] sarcoplasmic reticulum
|
(29 genes)
|
IBA
|
 |
|
GO:0030659 [list] [network] cytoplasmic vesicle membrane
|
(363 genes)
|
IBA
|
 |
|
GO:0005789 [list] [network] endoplasmic reticulum membrane
|
(569 genes)
|
IBA
|
 |
|
GO:0005783 [list] [network] endoplasmic reticulum
|
(906 genes)
|
IEA
|
 |
|
GO:0005886 [list] [network] plasma membrane
|
(3451 genes)
|
IBA
|
 |
|
GO:0016021 [list] [network] integral component of membrane
|
(6086 genes)
|
IEA
|
 |
|
GO:0016020 [list] [network] membrane
|
(7959 genes)
|
IEA
|
 |
|
| GO MF |
|
GO:0005220 [list] [network] inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
|
(4 genes)
|
IBA
IEA
|
 |
|
GO:0070679 [list] [network] inositol 1,4,5 trisphosphate binding
|
(15 genes)
|
IBA
IEA
|
 |
|
GO:0005262 [list] [network] calcium channel activity
|
(105 genes)
|
IEA
|
 |
|
GO:0035091 [list] [network] phosphatidylinositol binding
|
(160 genes)
|
IBA
|
 |
|
GO:0005509 [list] [network] calcium ion binding
|
(683 genes)
|
IBA
|
 |
|
| KEGG |
dre04020 [list] [network] Calcium signaling pathway (377 genes) |
 |
| dre04070 [list] [network] Phosphatidylinositol signaling system (118 genes) |
 |
| dre04114 [list] [network] Oocyte meiosis (151 genes) |
 |
| dre04210 [list] [network] Apoptosis (201 genes) |
 |
| dre04218 [list] [network] Cellular senescence (200 genes) |
 |
| dre04270 [list] [network] Vascular smooth muscle contraction (177 genes) |
 |
| dre04371 [list] [network] Apelin signaling pathway (193 genes) |
 |
| dre04540 [list] [network] Gap junction (132 genes) |
 |
| dre04621 [list] [network] NOD-like receptor signaling pathway (173 genes) |
 |
| dre04625 [list] [network] C-type lectin receptor signaling pathway (129 genes) |
 |
| dre04912 [list] [network] GnRH signaling pathway (132 genes) |
 |
| Protein |
XP_021323455.1
|
| BLAST |
XP_021323455.1
|
| Orthologous |
[Ortholog page]
ITPR1 (hsa)
ITPR2 (hsa)
ITPR3 (hsa)
Itpr1 (mmu)
Itpr2 (mmu)
Itpr3 (mmu)
Itpr1 (rno)
Itpr3 (rno)
Itpr (dme)
Itpr2 (rno)
itr-1 (cel)
ITPR1 (gga)
ITPR2 (gga)
ITPR3 (gga)
ITPR1 (cfa)
ITPR3 (cfa)
ITPR2 (cfa)
itpr1a (dre)
ITPR1 (mcc)
ITPR2 (mcc)
ITPR3 (mcc)
itpr3 (dre)
itpr1b (dre)
ITPR3 (fca)
ITPR1 (fca)
ITPR2 (fca)
|
Subcellular localization wolf |
|
plas 8,
E.R. 2
|
(predict for XP_021323455.1)
|
|
| Gene coexpression |
Network*for coexpressed genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| dre04625 |
C-type lectin receptor signaling pathway |
5 |
|
| dre04020 |
Calcium signaling pathway |
4 |
|
| dre04070 |
Phosphatidylinositol signaling system |
4 |
|
| dre04270 |
Vascular smooth muscle contraction |
3 |
|
| dre04371 |
Apelin signaling pathway |
3 |
|
Genes directly connected with itpr2 on the network
| coex z* |
Locus |
Function* |
Coexpression detail |
Entrez Gene ID* |
| 6.9 |
itprid2 |
ITPR interacting domain containing 2 |
[detail] |
553255 |
| 6.6 |
itpr3 |
inositol 1,4,5-trisphosphate receptor, type 3 |
[detail] |
794666 |
| 6.1 |
atp2a3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
[detail] |
568671 |
| 5.6 |
eml3 |
EMAP like 3 |
[detail] |
100533983 |
| 5.5 |
dock8 |
dedicator of cytokinesis 8 |
[detail] |
403040 |
| 5.2 |
ksr1b |
kinase suppressor of ras 1b |
[detail] |
556779 |
|
Coexpressed gene list |
[Coexpressed gene list for itpr2]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|