[←][→] gga  RAF1 Gene
functional annotation
Function   Raf-1 proto-oncogene, serine/threonine kinase  
GO BP
GO:0071550 [list] [network] death-inducing signaling complex assembly  (1 genes)  IEA  
GO:1902042 [list] [network] negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (1 genes)  IEA  
GO:0035773 [list] [network] insulin secretion involved in cellular response to glucose stimulus  (2 genes)  IEA  
GO:0007190 [list] [network] activation of adenylate cyclase activity  (3 genes)  IEA  
GO:0030878 [list] [network] thyroid gland development  (3 genes)  IEA  
GO:0035019 [list] [network] somatic stem cell population maintenance  (4 genes)  IEA  
GO:0048011 [list] [network] neurotrophin TRK receptor signaling pathway  (4 genes)  IEA  
GO:0035994 [list] [network] response to muscle stretch  (5 genes)  IEA  
GO:0048538 [list] [network] thymus development  (6 genes)  IEA  
GO:0045104 [list] [network] intermediate filament cytoskeleton organization  (7 genes)  IEA  
GO:0060324 [list] [network] face development  (12 genes)  IEA  
GO:0033138 [list] [network] positive regulation of peptidyl-serine phosphorylation  (17 genes)  IEA  
GO:0031333 [list] [network] negative regulation of protein-containing complex assembly  (25 genes)  IEA  
GO:0008285 [list] [network] negative regulation of cell population proliferation  (66 genes)  IEA  
GO:0006468 [list] [network] protein phosphorylation  (91 genes)  IEA  
GO:0035556 [list] [network] intracellular signal transduction  (111 genes)  IEA  
GO:0045944 [list] [network] positive regulation of transcription by RNA polymerase II  (138 genes)  IEA  
GO:0030154 [list] [network] cell differentiation  (417 genes)  IEA  
GO CC
GO:0031143 [list] [network] pseudopodium  (2 genes)  IEA  
GO:0016607 [list] [network] nuclear speck  (39 genes)  IEA  
GO:0005739 [list] [network] mitochondrion  (146 genes)  IBA  
GO:0005829 [list] [network] cytosol  (324 genes)  IBA  
GO:0005886 [list] [network] plasma membrane  (477 genes)  IBA ISS  
GO:0005737 [list] [network] cytoplasm  (1251 genes)  ISS  
GO MF
GO:0031267 [list] [network] small GTPase binding  (11 genes)  IEA  
GO:0106310 [list] [network] protein serine kinase activity  (32 genes)  IEA  
GO:0106311 [list] [network] protein threonine kinase activity  (32 genes)  IEA  
GO:0004672 [list] [network] protein kinase activity  (80 genes)  IBA  
GO:0042802 [list] [network] identical protein binding  (164 genes)  IEA  
GO:0005524 [list] [network] ATP binding  (217 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (481 genes)  IEA  
KEGG gga04010 [list] [network] MAPK signaling pathway (260 genes)
gga04012 [list] [network] ErbB signaling pathway (78 genes)
gga04068 [list] [network] FoxO signaling pathway (122 genes)
gga04140 [list] [network] Autophagy - animal (131 genes)
gga04150 [list] [network] mTOR signaling pathway (143 genes)
gga04210 [list] [network] Apoptosis (125 genes)
gga04218 [list] [network] Cellular senescence (144 genes)
gga04270 [list] [network] Vascular smooth muscle contraction (122 genes)
gga04370 [list] [network] VEGF signaling pathway (58 genes)
gga04371 [list] [network] Apelin signaling pathway (124 genes)
gga04510 [list] [network] Focal adhesion (191 genes)
gga04540 [list] [network] Gap junction (84 genes)
gga04625 [list] [network] C-type lectin receptor signaling pathway (87 genes)
gga04810 [list] [network] Regulation of actin cytoskeleton (195 genes)
gga04910 [list] [network] Insulin signaling pathway (122 genes)
gga04912 [list] [network] GnRH signaling pathway (84 genes)
gga04914 [list] [network] Progesterone-mediated oocyte maturation (80 genes)
gga04916 [list] [network] Melanogenesis (91 genes)
gga05132 [list] [network] Salmonella infection (234 genes)
gga05164 [list] [network] Influenza A (139 genes)
Protein NP_990638.1  XP_015148495.1  XP_015148496.1  XP_015148497.1  XP_015148498.1  XP_015148499.1  XP_015148500.1  XP_025010214.1  XP_025010215.1  XP_040502065.1  XP_040502066.1  XP_040502067.1  XP_040502068.1  XP_040502069.1  XP_040502070.1 
BLAST NP_990638.1  XP_015148495.1  XP_015148496.1  XP_015148497.1  XP_015148498.1  XP_015148499.1  XP_015148500.1  XP_025010214.1  XP_025010215.1  XP_040502065.1  XP_040502066.1  XP_040502067.1  XP_040502068.1  XP_040502069.1  XP_040502070.1 
Orthologous [Ortholog page] ARAF (hsa)  RAF1 (hsa)  Araf (mmu)  Raf1 (rno)  raf1a (dre)  Raf (dme)  Araf (rno)  Raf1 (mmu)  lin-45 (cel)  araf (dre)  RAF1 (cfa)  ARAF (cfa)  raf1b (dre)  RAF1 (mcc)  ARAF (mcc)  itt1 (spo)  ARAF (fca)  RAF1 (fca) 
Subcellular
localization
wolf
nucl 7,  cyto 3  (predict for NP_990638.1)
nucl 7,  cyto 3  (predict for XP_015148495.1)
nucl 7,  cyto 3  (predict for XP_015148496.1)
nucl 7,  cyto 3  (predict for XP_015148497.1)
nucl 7,  cyto 3  (predict for XP_015148498.1)
nucl 7,  cyto 3  (predict for XP_015148499.1)
nucl 7,  cyto 2  (predict for XP_015148500.1)
nucl 7,  cyto 3  (predict for XP_025010214.1)
nucl 7,  cyto 3  (predict for XP_025010215.1)
nucl 7,  cyto 3  (predict for XP_040502065.1)
nucl 7,  cyto 3  (predict for XP_040502066.1)
nucl 7,  cyto 3  (predict for XP_040502067.1)
nucl 7,  cyto 2  (predict for XP_040502068.1)
nucl 7,  cyto 3  (predict for XP_040502069.1)
nucl 7,  cyto 3  (predict for XP_040502070.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga04140 Autophagy - animal 2
gga04150 mTOR signaling pathway 2
gga04010 MAPK signaling pathway 2
gga04912 GnRH signaling pathway 2
gga05164 Influenza A 2
Genes directly connected with RAF1 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
6.0 UBXN2A UBX domain protein 2A [detail] 421973
5.0 ARMC8 armadillo repeat containing 8 [detail] 424731
5.0 MAP3K4 mitogen-activated protein kinase kinase kinase 4 [detail] 421579
4.7 NSMAF neutral sphingomyelinase activation associated factor [detail] 421137
Coexpressed
gene list		 [Coexpressed gene list for RAF1]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 396245      
Refseq ID (protein) NP_990638.1 
XP_015148495.1 
XP_015148496.1 
XP_015148497.1 
XP_015148498.1 
XP_015148499.1 
XP_015148500.1 
XP_025010214.1 
XP_025010215.1 
XP_040502065.1 
XP_040502066.1 
XP_040502067.1 
XP_040502068.1 
XP_040502069.1 
XP_040502070.1 


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