[←][→] gga  SRC Gene
functional annotation
Function   SRC proto-oncogene, non-receptor tyrosine kinase  
GO BP
GO:0050847 [list] [network] progesterone receptor signaling pathway  (1 genes)  IBA  
GO:0045453 [list] [network] bone resorption  (2 genes)  IBA  
GO:0036035 [list] [network] osteoclast development  (3 genes)  IBA  
GO:0007173 [list] [network] epidermal growth factor receptor signaling pathway  (8 genes)  IBA  
GO:2001237 [list] [network] negative regulation of extrinsic apoptotic signaling pathway  (8 genes)  IBA  
GO:2001243 [list] [network] negative regulation of intrinsic apoptotic signaling pathway  (8 genes)  IBA  
GO:0018108 [list] [network] peptidyl-tyrosine phosphorylation  (39 genes)  IEA  
GO:0045087 [list] [network] innate immune response  (49 genes)  IBA  
GO:0007169 [list] [network] transmembrane receptor protein tyrosine kinase signaling pathway  (65 genes)  IBA  
GO:0051726 [list] [network] regulation of cell cycle  (106 genes)  IDA  
GO:0007155 [list] [network] cell adhesion  (114 genes)  IBA  
GO:0007049 [list] [network] cell cycle  (156 genes)  IEA  
GO:0030154 [list] [network] cell differentiation  (417 genes)  IBA  
GO CC
GO:0031234 [list] [network] extrinsic component of cytoplasmic side of plasma membrane  (13 genes)  IBA  
GO:0005925 [list] [network] focal adhesion  (24 genes)  ISS  
GO:0005743 [list] [network] mitochondrial inner membrane  (40 genes)  ISS  
GO:0048471 [list] [network] perinuclear region of cytoplasm  (53 genes)  ISS  
GO:0010008 [list] [network] endosome membrane  (59 genes)  IDA  
GO:0030054 [list] [network] cell junction  (190 genes)  ISS  
GO:0005856 [list] [network] cytoskeleton  (247 genes)  IDA  
GO:0005829 [list] [network] cytosol  (324 genes)  TAS  
GO:0005886 [list] [network] plasma membrane  (477 genes)  IDA  
GO:0032991 [list] [network] protein-containing complex  (651 genes)  IMP  
GO:0016020 [list] [network] membrane  (810 genes)  ISS  
GO:0005634 [list] [network] nucleus  (876 genes)  IDA  
GO MF
GO:0071253 [list] [network] connexin binding  (1 genes)  IPI  
GO:0004715 [list] [network] non-membrane spanning protein tyrosine kinase activity  (11 genes)  IBA  
GO:0019903 [list] [network] protein phosphatase binding  (13 genes)  IPI  
GO:0070851 [list] [network] growth factor receptor binding  (19 genes)  IBA  
GO:0020037 [list] [network] heme binding  (26 genes)  ISS  
GO:0004714 [list] [network] transmembrane receptor protein tyrosine kinase activity  (37 genes)  IEA  
GO:0004713 [list] [network] protein tyrosine kinase activity  (38 genes)  EXP IBA  
GO:0005102 [list] [network] signaling receptor binding  (168 genes)  IBA  
GO:0005524 [list] [network] ATP binding  (217 genes)  IEA  
GO:0005515 [list] [network] protein binding  (780 genes)  IPI  
KEGG gga04012 [list] [network] ErbB signaling pathway (78 genes)
gga04137 [list] [network] Mitophagy - animal (64 genes)
gga04144 [list] [network] Endocytosis (232 genes)
gga04370 [list] [network] VEGF signaling pathway (58 genes)
gga04510 [list] [network] Focal adhesion (191 genes)
gga04520 [list] [network] Adherens junction (71 genes)
gga04530 [list] [network] Tight junction (157 genes)
gga04540 [list] [network] Gap junction (84 genes)
gga04625 [list] [network] C-type lectin receptor signaling pathway (87 genes)
gga04810 [list] [network] Regulation of actin cytoskeleton (195 genes)
gga04912 [list] [network] GnRH signaling pathway (84 genes)
gga05168 [list] [network] Herpes simplex virus 1 infection (152 genes)
Protein NP_990788.3  XP_015151832.2  XP_015151833.2  XP_015151834.2  XP_040506588.1 
BLAST NP_990788.3  XP_015151832.2  XP_015151833.2  XP_015151834.2  XP_040506588.1 
Orthologous [Ortholog page] BLK (hsa)  FGR (hsa)  FRK (hsa)  FYN (hsa)  HCK (hsa)  LCK (hsa)  LYN (hsa)  PTK6 (hsa)  SRC (hsa)  SRMS (hsa)  YES1 (hsa)  Blk (mmu)  Fgr (mmu)  Frk (mmu)  Fyn (mmu)  Hck (mmu)  Lck (mmu)  Lyn (mmu)  Ptk6 (mmu)  Src (mmu)  Srms (mmu)  Yes1 (mmu)  Yes1 (rno)  Fyn (rno)  Hck (rno)  Src42A (dme)  Src64B (dme)  Fgr (rno)  Frk (rno)  Lyn (rno)  Src (rno)  src-1 (cel)  F26E4.5 (cel)  src-2 (cel)  T25B9.4 (cel)  W01B6.5 (cel)  Srms (rno)  Lck (rno)  src (dre)  yrk (dre)  Blk (rno)  Ptk6 (rno)  fyna (dre)  YES1 (gga)  FYN (gga)  LCK (gga)  YES1 (cfa)  yes1 (dre)  lck (dre)  PTK6 (gga)  HCK (gga)  LYN (gga)  FRK (gga)  BLK (gga)  lyn (dre)  FYN (cfa)  SRMS (cfa)  LYN (cfa)  LCK (cfa)  FRK (cfa)  HCK (cfa)  SRC (cfa)  BLK (cfa)  FGR (cfa)  ptk6a (dre)  frk (dre)  blk (dre)  FYN (mcc)  fynb (dre)  BLK (mcc)  YES1 (mcc)  LYN (mcc)  SRC (mcc)  HCK (mcc)  FRK (mcc)  FGR (mcc)  LCK (mcc)  SRMS (mcc)  PTK6 (mcc)  ptk6b (dre)  FGR (gga)  nda2 (spo)  atb2 (spo)  srms (dre)  FGR (fca)  BLK (fca)  FYN (fca)  FRK (fca)  YES1 (fca)  LYN (fca)  LCK (fca)  SRMS (fca)  PTK6 (fca)  SRC (fca)  HCK (fca)  hck (dre)  LOC102156300 (cfa)  LOC119865729 (cfa) 
Subcellular
localization
wolf
nucl 6,  cyto_nucl 5,  cyto 3  (predict for NP_990788.3)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for XP_015151832.2)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for XP_015151833.2)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for XP_015151834.2)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for XP_040506588.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
gga05168 Herpes simplex virus 1 infection 4
gga04144 Endocytosis 3
gga05164 Influenza A 3
gga04010 MAPK signaling pathway 2
gga04012 ErbB signaling pathway 2
Genes directly connected with SRC on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
6.2 CPN2 carboxypeptidase N subunit 2 [detail] 424899
5.7 PML PML nuclear body scaffold [detail] 415302
5.1 PAK4 p21 (RAC1) activated kinase 4 [detail] 770462
5.1 CACNA1H calcium voltage-gated channel subunit alpha1 H [detail] 416526
4.7 CASKIN1 CASK interacting protein 1 [detail] 416556
4.4 SH3PXD2B SH3 and PX domains 2B [detail] 427625
3.4 OCSTAMP osteoclast stimulatory transmembrane protein [detail] 419205
Coexpressed
gene list		 [Coexpressed gene list for SRC]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 396442      
Refseq ID (protein) NP_990788.3 
XP_015151832.2 
XP_015151833.2 
XP_015151834.2 
XP_040506588.1 


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