| functional annotation |
| Function |
mitogen activated protein kinase kinase kinase 2 |
|
| GO BP |
|
GO:0071260 [list] [network] cellular response to mechanical stimulus
|
(134 genes)
|
ISO
|
 |
|
GO:0000165 [list] [network] MAPK cascade
|
(151 genes)
|
IEA
|
|
|
GO:0008283 [list] [network] cell population proliferation
|
(578 genes)
|
NAS
|
|
|
GO:0006468 [list] [network] protein phosphorylation
|
(680 genes)
|
IDA
|
|
|
GO:0045893 [list] [network] positive regulation of transcription, DNA-templated
|
(1618 genes)
|
ISO
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004709 [list] [network] MAP kinase kinase kinase activity
|
(24 genes)
|
IDA
|
|
|
GO:0004672 [list] [network] protein kinase activity
|
(557 genes)
|
ISO
|
|
|
GO:0019901 [list] [network] protein kinase binding
|
(744 genes)
|
ISO
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1380 genes)
|
IEA
|
|
|
| KEGG |
rno04010 [list] [network] MAPK signaling pathway (293 genes) |
 |
| rno04540 [list] [network] Gap junction (87 genes) |
|
| rno04912 [list] [network] GnRH signaling pathway (90 genes) |
|
| Protein |
NP_612512.1
XP_038952487.1
|
| BLAST |
NP_612512.1
XP_038952487.1
|
| Orthologous |
[Ortholog page]
MAP3K3 (hsa)
MAP3K2 (hsa)
Map3k2 (mmu)
Map3k3 (mmu)
Map3k3 (rno)
MAP3K3 (gga)
LOC420419 (gga)
MAP3K2 (gga)
MAP3K3 (cfa)
map3k2 (dre)
map3k3 (dre)
MAP3K2 (cfa)
MAP3K3 (mcc)
STE11 (sce)
map3k22 (dre)
MAP3K2 (mcc)
MAP3K3 (fca)
MAP3K2 (fca)
|
Subcellular
localization
wolf |
|
nucl 8,
cyto_nucl 5,
cyto 2
|
(predict for NP_612512.1)
|
|
nucl 4,
cyto_nucl 3,
mito 3,
cyto 3
|
(predict for XP_038952487.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| rno04115 |
p53 signaling pathway |
2 |
 |
| rno05206 |
MicroRNAs in cancer |
2 |
 |
| rno04068 |
FoxO signaling pathway |
2 |
 |
| rno04010 |
MAPK signaling pathway |
2 |
 |
| rno04150 |
mTOR signaling pathway |
2 |
 |
Genes directly connected with Map3k2 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 12.2 |
Smg1 |
SMG1, nonsense mediated mRNA decay associated PI3K related kinase |
[detail] |
691397 |
| 11.1 |
Ino80d |
INO80 complex subunit D |
[detail] |
316440 |
| 10.9 |
Rictor |
RPTOR independent companion of MTOR, complex 2 |
[detail] |
310131 |
| 10.7 |
Bdp1 |
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB |
[detail] |
294687 |
| 10.1 |
Ptar1 |
protein prenyltransferase alpha subunit repeat containing 1 |
[detail] |
286972 |
| 10.0 |
Zfp292 |
zinc finger protein 292 |
[detail] |
50552 |
| 9.1 |
Med13 |
mediator complex subunit 13 |
[detail] |
303403 |
| 8.8 |
Ubxn7 |
UBX domain protein 7 |
[detail] |
303878 |
| 8.1 |
Ago3 |
argonaute RISC catalytic component 3 |
[detail] |
313593 |
| 7.9 |
Slc5a3 |
solute carrier family 5 member 3 |
[detail] |
114507 |
| 7.8 |
Lpp |
LIM domain containing preferred translocation partner in lipoma |
[detail] |
288010 |
| 7.6 |
Zc3h12c |
zinc finger CCCH type containing 12C |
[detail] |
315658 |
| 7.5 |
Tnpo1 |
transportin 1 |
[detail] |
309126 |
| 6.9 |
Fgd4 |
FYVE, RhoGEF and PH domain containing 4 |
[detail] |
246174 |
| 6.7 |
Mdm4 |
MDM4 regulator of p53 |
[detail] |
304798 |
| 6.7 |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
[detail] |
114486 |
| 6.2 |
Zbtb44 |
zinc finger and BTB domain containing 44 |
[detail] |
363035 |
|
Coexpressed
gene list |
[Coexpressed gene list for Map3k2]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Map3k2 Gene
