| functional annotation |
| Function |
mitogen-activated protein kinase kinase 2b |
|
| GO BP |
|
GO:0006468 [list] [network] protein phosphorylation
|
(744 genes)
|
IEA
|
 |
|
GO:0016310 [list] [network] phosphorylation
|
(977 genes)
|
IEA
|
|
|
| GO CC |
|
| GO MF |
|
GO:0004708 [list] [network] MAP kinase kinase activity
|
(15 genes)
|
IBA
|
|
|
GO:0004674 [list] [network] protein serine/threonine kinase activity
|
(548 genes)
|
IEA
|
|
|
GO:0004672 [list] [network] protein kinase activity
|
(756 genes)
|
IEA
|
|
|
GO:0016301 [list] [network] kinase activity
|
(989 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1578 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2320 genes)
|
IEA
|
|
|
GO:0016740 [list] [network] transferase activity
|
(2575 genes)
|
IEA
|
|
|
| KEGG |
dre04010 [list] [network] MAPK signaling pathway (409 genes) |
 |
| dre04012 [list] [network] ErbB signaling pathway (110 genes) |
|
| dre04068 [list] [network] FoxO signaling pathway (181 genes) |
|
| dre04140 [list] [network] Autophagy - animal (200 genes) |
|
| dre04150 [list] [network] mTOR signaling pathway (206 genes) |
|
| dre04210 [list] [network] Apoptosis (201 genes) |
|
| dre04218 [list] [network] Cellular senescence (200 genes) |
|
| dre04270 [list] [network] Vascular smooth muscle contraction (177 genes) |
|
| dre04370 [list] [network] VEGF signaling pathway (81 genes) |
|
| dre04371 [list] [network] Apelin signaling pathway (193 genes) |
|
| dre04540 [list] [network] Gap junction (132 genes) |
|
| dre04620 [list] [network] Toll-like receptor signaling pathway (106 genes) |
|
| dre04810 [list] [network] Regulation of actin cytoskeleton (308 genes) |
|
| dre04910 [list] [network] Insulin signaling pathway (180 genes) |
|
| dre04912 [list] [network] GnRH signaling pathway (132 genes) |
|
| dre04916 [list] [network] Melanogenesis (147 genes) |
|
| dre05132 [list] [network] Salmonella infection (332 genes) |
|
| Protein |
NP_001121753.1
XP_009297220.1
XP_021333936.1
|
| BLAST |
NP_001121753.1
XP_009297220.1
XP_021333936.1
|
| Orthologous |
[Ortholog page]
MAP2K1 (hsa)
MAP2K2 (hsa)
Map2k1 (mmu)
Map2k2 (mmu)
Dsor1 (dme)
Map2k2 (rno)
Map2k1 (rno)
mek-2 (cel)
MAP2K2 (gga)
map2k1 (dre)
MAP2K1 (gga)
MAP2K1 (cfa)
map2k2a (dre)
MAP2K2 (cfa)
MAP2K1 (mcc)
MAP2K2 (mcc)
PBS2 (sce)
pab2 (spo)
MAP2K1 (fca)
MAP2K2 (fca)
|
Subcellular
localization
wolf |
|
cyto 8,
cyto_nucl 5,
cyto_plas 4,
nucl 2
|
(predict for NP_001121753.1)
|
|
cyto 5,
cyto_nucl 4,
cyto_plas 3,
nucl 3,
golg 1
|
(predict for XP_009297220.1)
|
|
cyto 7,
cyto_nucl 5,
cyto_plas 4,
nucl 2
|
(predict for XP_021333936.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| dre05132 |
Salmonella infection |
3 |
 |
| dre04140 |
Autophagy - animal |
2 |
 |
| dre04144 |
Endocytosis |
2 |
 |
| dre04810 |
Regulation of actin cytoskeleton |
2 |
 |
Genes directly connected with map2k2b on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 4.9 |
actr2b |
actin related protein 2b |
[detail] |
554861 |
| 4.9 |
mfap3l |
microfibril associated protein 3 like |
[detail] |
557798 |
| 4.7 |
prkra |
protein kinase, interferon-inducible double stranded RNA dependent activator |
[detail] |
557370 |
| 4.6 |
armc6 |
armadillo repeat containing 6 |
[detail] |
555425 |
|
Coexpressed
gene list |
[Coexpressed gene list for map2k2b]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
map2k2b Gene
