KEGG 04922 Glucagon signaling pathway
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04922 Glucagon signaling pathway 39
hsa00010 Glycolysis / Gluconeogenesis 17
hsa04910 Insulin signaling pathway 16
hsa04020 Calcium signaling pathway 14
hsa04022 cGMP-PKG signaling pathway 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04922 Glucagon signaling pathway 39
mmu04910 Insulin signaling pathway 28
mmu00010 Glycolysis / Gluconeogenesis 21
mmu01200 Carbon metabolism 19
mmu04066 HIF-1 signaling pathway 17
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04922 Glucagon signaling pathway 41
rno04910 Insulin signaling pathway 22
rno00010 Glycolysis / Gluconeogenesis 17
rno04931 Insulin resistance 16
rno04020 Calcium signaling pathway 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04922 Glucagon signaling pathway 28
mcc00010 Glycolysis / Gluconeogenesis 17
mcc01200 Carbon metabolism 13
mcc05230 Central carbon metabolism in cancer 11
mcc04152 AMPK signaling pathway 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04922 Glucagon signaling pathway 28
cfa00010 Glycolysis / Gluconeogenesis 14
cfa04910 Insulin signaling pathway 13
cfa04152 AMPK signaling pathway 12
cfa01200 Carbon metabolism 11
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04922 Glucagon signaling pathway 41
fca04066 HIF-1 signaling pathway 17
fca04921 Oxytocin signaling pathway 17
fca04020 Calcium signaling pathway 16
fca04910 Insulin signaling pathway 15
Gene list in the network
Symbol Function*
ADCY2 adenylate cyclase 2
AFM afamin
AKT2 AKT serine/threonine kinase 2
ATF4 activating transcription factor 4
ATP1A2 ATPase Na+/K+ transporting subunit alpha 2
ATP5F1A ATP synthase F1 subunit alpha
ATP5F1B ATP synthase F1 subunit beta
CACNA1S calcium voltage-gated channel subunit alpha1 S
CALM2 calmodulin 2
CALML3 calmodulin like 3
CAMK2G calcium/calmodulin dependent protein kinase II gamma
CREB1 cAMP responsive element binding protein 1
ATF2 activating transcription factor 2
CREBBP CREB binding protein
CYP27A1 cytochrome P450 family 27 subfamily A member 1
ENO1 enolase 1
EP300 E1A binding protein p300
FBP1 fructose-bisphosphatase 1
G6PC1 glucose-6-phosphatase catalytic subunit 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GNAS GNAS complex locus
GPI glucose-6-phosphate isomerase
GYS1 glycogen synthase 1
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
ITPR2 inositol 1,4,5-trisphosphate receptor type 2
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1
PCK1 phosphoenolpyruvate carboxykinase 1
PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial
PDHA1 pyruvate dehydrogenase E1 subunit alpha 1
PDHB pyruvate dehydrogenase E1 subunit beta
PFKM phosphofructokinase, muscle
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1
PGK1 phosphoglycerate kinase 1
PHKA1 phosphorylase kinase regulatory subunit alpha 1
PHKA2 phosphorylase kinase regulatory subunit alpha 2
PHKB phosphorylase kinase regulatory subunit beta
PHKG1 phosphorylase kinase catalytic subunit gamma 1
PKM pyruvate kinase M1/2
PPP3R1 protein phosphatase 3 regulatory subunit B, alpha
PYGM glycogen phosphorylase, muscle associated
SLC2A2 solute carrier family 2 member 2
USF2 upstream transcription factor 2, c-fos interacting
FBP2 fructose-bisphosphatase 2
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
ACTR2 actin related protein 2
SIRT1 sirtuin 1
SF3B1 splicing factor 3b subunit 1
ACP6 acid phosphatase 6, lysophosphatidic
CALML5 calmodulin like 5
PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3
PPP4R3A protein phosphatase 4 regulatory subunit 3A
AKTIP AKT interacting protein
CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1
CREB3L4 cAMP responsive element binding protein 3 like 4
Symbol Function*
Akt1 thymoma viral proto-oncogene 1
Akt2 thymoma viral proto-oncogene 2
Aldoa aldolase A, fructose-bisphosphate
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
Calm1 calmodulin 1
Calm2 calmodulin 2
Calm3 calmodulin 3
Crebbp CREB binding protein
Eno1 enolase 1, alpha non-neuron
Fbp2 fructose bisphosphatase 2
Fbp1 fructose bisphosphatase 1
G6pc glucose-6-phosphatase, catalytic
Gnaq guanine nucleotide binding protein, alpha q polypeptide
Gpi1 glucose-6-phosphate isomerase 1
Gys1 glycogen synthase 1, muscle
Hk1 hexokinase 1
Hk2 hexokinase 2
Ldha lactate dehydrogenase A
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic
Pdha1 pyruvate dehydrogenase E1 alpha 1
Pfkl phosphofructokinase, liver, B-type
Pfkm phosphofructokinase, muscle
Pgam1 phosphoglycerate mutase 1
Pgk1 phosphoglycerate kinase 1
Phka1 phosphorylase kinase alpha 1
Phkg1 phosphorylase kinase gamma 1
Pkm pyruvate kinase, muscle
Plcd4 phospholipase C, delta 4
Ppara peroxisome proliferator activated receptor alpha
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
Prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Pygm muscle glycogen phosphorylase
Acsm3 acyl-CoA synthetase medium-chain family member 3
Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1
Thrb thyroid hormone receptor beta
Tkt transketolase
Tpi1 triosephosphate isomerase 1
Map2k1 mitogen-activated protein kinase kinase 1
Slc4a4 solute carrier family 4 (anion exchanger), member 4
Pgam2 phosphoglycerate mutase 2
Pfkp phosphofructokinase, platelet
Pdhb pyruvate dehydrogenase (lipoamide) beta
Calml3 calmodulin-like 3
Tmem38a transmembrane protein 38A
Calm4 calmodulin 4
Slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3
Phkb phosphorylase kinase beta
Csnk1g2 casein kinase 1, gamma 2
Gck glucokinase
Acaca acetyl-Coenzyme A carboxylase alpha
Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit
Pygl liver glycogen phosphorylase
Gm94 predicted gene 94
Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1
Gys2 glycogen synthase 2
Kat6a K(lysine) acetyltransferase 6A
Ppp1r3b protein phosphatase 1, regulatory subunit 3B
Ep300 E1A binding protein p300
Symbol Function*
Aldob aldolase, fructose-bisphosphate B
Atp1b2 ATPase Na+/K+ transporting subunit beta 2
Calm1 calmodulin 1
Calm3 calmodulin 3
Camk2d calcium/calmodulin-dependent protein kinase II delta
Eno1 enolase 1
Fbp1 fructose-bisphosphatase 1
Ganc glucosidase, alpha; neutral C
Gck glucokinase
Ldha lactate dehydrogenase A
Pde4d phosphodiesterase 4D
Pgam1 phosphoglycerate mutase 1
Pgk1 phosphoglycerate kinase 1
Plcb1 phospholipase C beta 1
Ppp3ca protein phosphatase 3 catalytic subunit alpha
Ppp3cb protein phosphatase 3 catalytic subunit beta
Pygm glycogen phosphorylase, muscle associated
Slc2a1 solute carrier family 2 member 1
Tpi1 triosephosphate isomerase 1
Pgam2 phosphoglycerate mutase 2
Plcb4 phospholipase C, beta 4
Hk1 hexokinase 1
Itpr1 inositol 1,4,5-trisphosphate receptor, type 1
Slc2a2 solute carrier family 2 member 2
Gys2 glycogen synthase 2
G6pc1 glucose-6-phosphatase catalytic subunit 1
Pygb glycogen phosphorylase B
Pfkl phosphofructokinase, liver type
Cpt1b carnitine palmitoyltransferase 1B
Phkg1 phosphorylase kinase catalytic subunit gamma 1
Pde3b phosphodiesterase 3B
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha
Calm2 calmodulin 2
Pfkp phosphofructokinase, platelet
Acaca acetyl-CoA carboxylase alpha
Pygl glycogen phosphorylase L
Phka1 phosphorylase kinase regulatory subunit alpha 1
Pfkm phosphofructokinase, muscle
Atf4 activating transcription factor 4
Itpr2 inositol 1,4,5-trisphosphate receptor, type 2
Ppargc1a PPARG coactivator 1 alpha
Acacb acetyl-CoA carboxylase beta
Gmpr guanosine monophosphate reductase
Plcd4 phospholipase C, delta 4
Ero1a endoplasmic reticulum oxidoreductase 1 alpha
Ppp1r3b protein phosphatase 1, regulatory subunit 3B
Trib3 tribbles pseudokinase 3
Dhrs7c dehydrogenase/reductase 7C
Cidea cell death-inducing DFFA-like effector a
Gpi glucose-6-phosphate isomerase
Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3
Tmem38a transmembrane protein 38a
Ppp4r3a protein phosphatase 4, regulatory subunit 3A
Creb3l3 cAMP responsive element binding protein 3-like 3
Ppp4r3b protein phosphatase 4, regulatory subunit 3B
Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Phkb phosphorylase kinase regulatory subunit beta
Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Pck1 phosphoenolpyruvate carboxykinase 1
Capza2 capping actin protein of muscle Z-line subunit alpha 2
Akap11 A-kinase anchoring protein 11
Cidec cell death-inducing DFFA-like effector c
Gys1 glycogen synthase 1
Symbol Function*
PDHB pyruvate dehydrogenase E1 subunit beta
GYS1 glycogen synthase 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
CYP2C8 cytochrome P450 family 2 subfamily C member 8
LDHC lactate dehydrogenase C
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
LDHA lactate dehydrogenase A
SLC2A2 solute carrier family 2 member 2
SIRT1 sirtuin 1
LOC696959 phosphoglycerate mutase 1
TCAP titin-cap
PKM pyruvate kinase M1/2
UQCRC2 ubiquinol-cytochrome c reductase core protein II
PHKG1 phosphorylase kinase catalytic subunit gamma 1
CREBBP CREB binding protein
COQ9 coenzyme Q9
GYS2 glycogen synthase 2
PGAM1 phosphoglycerate mutase 1
EP300 E1A binding protein p300
PFKM phosphofructokinase, muscle
ITPR2 inositol 1,4,5-trisphosphate receptor type 2
CREB1 cAMP responsive element binding protein 1
FBP1 fructose-bisphosphatase 1
ENO1 enolase 1
LOC710798 pyruvate kinase PKM
G6PC1 glucose-6-phosphatase catalytic subunit 1
TPI1 triosephosphate isomerase 1
G6PC3 glucose-6-phosphatase catalytic subunit 3
CEP350 centrosomal protein 350
KANSL1 KAT8 regulatory NSL complex subunit 1
TNRC18 trinucleotide repeat containing 18
PYGM glycogen phosphorylase, muscle associated
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ARID1A AT-rich interaction domain 1A
CPT1B carnitine palmitoyltransferase 1B
CYP4A11 cytochrome P450 family 4 subfamily A member 11
CTDNEP1 CTD nuclear envelope phosphatase 1
PFKP phosphofructokinase, platelet
PDHA1 pyruvate dehydrogenase E1 subunit alpha 1
PPP4R3A protein phosphatase 4 regulatory subunit 3A
FBP2 fructose-bisphosphatase 2
CFHR2 complement factor H related 2
Symbol Function*
G6PC1 glucose-6-phosphatase catalytic subunit 1
PRKACA protein kinase cAMP-activated catalytic subunit alpha
PCK1 phosphoenolpyruvate carboxykinase 1
PKM pyruvate kinase M1/2
GNAS GNAS complex locus
BICRAL BRD4 interacting chromatin remodeling complex associated protein like
PGAM2 phosphoglycerate mutase 2
PLCB3 phospholipase C beta 3
FBP1 fructose-bisphosphatase 1
FBP2 fructose-bisphosphatase 2
LDHA lactate dehydrogenase A
PYGB glycogen phosphorylase B
TAF4 TATA-box binding protein associated factor 4
FOXO1 forkhead box O1
PGAM1 phosphoglycerate mutase 1
NRAP nebulin related anchoring protein
PFKP phosphofructokinase, platelet
FAM162A family with sequence similarity 162 member A
POLR2A RNA polymerase II subunit A
ENO1 enolase 1
ALDOA aldolase, fructose-bisphosphate A
CREBBP CREB binding protein
PGK1 phosphoglycerate kinase 1
CPT1B carnitine palmitoyltransferase 1B
SLC2A1 solute carrier family 2 member 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
EHBP1L1 EH domain binding protein 1 like 1
CIDEC cell death inducing DFFA like effector c
FKBP8 FKBP prolyl isomerase 8
CALML5 calmodulin like 5
ARID1A AT-rich interaction domain 1A
PFKL phosphofructokinase, liver type
ACVR1C activin A receptor type 1C
PPP4C protein phosphatase 4 catalytic subunit
AKT1 AKT serine/threonine kinase 1
PACS2 phosphofurin acidic cluster sorting protein 2
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
CHKB choline kinase beta
PHKG2 phosphorylase kinase catalytic subunit gamma 2
PYGM glycogen phosphorylase, muscle associated
GPI glucose-6-phosphate isomerase
GYS1 glycogen synthase 1
CREB3L4 cAMP responsive element binding protein 3 like 4
EP300 E1A binding protein p300
SPEN spen family transcriptional repressor
CAPN3 calpain 3
LOC102153034 calmodulin-like protein 3
Symbol Function*
GAPDH glyceraldehyde-3-phosphate dehydrogenase
SLC2A1 solute carrier family 2 member 1
KLHL38 kelch like family member 38
PDHA1 pyruvate dehydrogenase E1 subunit alpha 1
ZNF106 zinc finger protein 106
PHKG1 phosphorylase kinase catalytic subunit gamma 1
LOC101081229 pyruvate kinase PKM
CLTCL1 clathrin heavy chain like 1
LRRC38 leucine rich repeat containing 38
CDK14 cyclin dependent kinase 14
PITPNM1 phosphatidylinositol transfer protein membrane associated 1
TMOD1 tropomodulin 1
MYH10 myosin heavy chain 10
ACACA acetyl-CoA carboxylase alpha
FBXO32 F-box protein 32
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
RCOR1 REST corepressor 1
CAMK2A calcium/calmodulin dependent protein kinase II alpha
KMT2E lysine methyltransferase 2E (inactive)
TPI1 triosephosphate isomerase 1
PPP3CB protein phosphatase 3 catalytic subunit beta
PGK1 phosphoglycerate kinase 1
DDHD2 DDHD domain containing 2
SCN4B sodium voltage-gated channel beta subunit 4
DCP1A decapping mRNA 1A
ITPR3 inositol 1,4,5-trisphosphate receptor type 3
ISCU iron-sulfur cluster assembly enzyme
TRIM72 tripartite motif containing 72
EP300 E1A binding protein p300
SPTB spectrin beta, erythrocytic
PHKB phosphorylase kinase regulatory subunit beta
PFKM phosphofructokinase, muscle
GRK5 G protein-coupled receptor kinase 5
PPP3R1 protein phosphatase 3 regulatory subunit B, alpha
PFKL phosphofructokinase, liver type
ARID1B AT-rich interaction domain 1B
PYGB glycogen phosphorylase B
LOC101091541 phosphatidylinositol phosphatase PTPRQ
SIK2 salt inducible kinase 2
PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3
PLCB1 phospholipase C beta 1
PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
LDHB lactate dehydrogenase B
AKT3 AKT serine/threonine kinase 3
ENO1 enolase 1
ADCY2 adenylate cyclase 2
CREBBP CREB binding protein
CALM1 calmodulin 1
PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1
PGAM2 phosphoglycerate mutase 2
PPP4R3A protein phosphatase 4 regulatory subunit 3A
PPARA peroxisome proliferator activated receptor alpha
NT5C1A 5'-nucleotidase, cytosolic IA
PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
ANK1 ankyrin 1
ALAD aminolevulinate dehydratase
PHKA1 phosphorylase kinase regulatory subunit alpha 1
LOC101097072 ATP-dependent 6-phosphofructokinase, platelet type
PPP3CA protein phosphatase 3 catalytic subunit alpha
CAMK2G calcium/calmodulin dependent protein kinase II gamma
CAMK2B calcium/calmodulin dependent protein kinase II beta
PGAM1 phosphoglycerate mutase 1
CALML4 calmodulin like 4
LDHA lactate dehydrogenase A
ADGRV1 adhesion G protein-coupled receptor V1
ITPR1 inositol 1,4,5-trisphosphate receptor type 1
GYS1 glycogen synthase 1
PYGM glycogen phosphorylase, muscle associated
GPATCH8 G-patch domain containing 8
LOC111556187 calmodulin-like protein 4
PFKP phosphofructokinase, platelet


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