KEGG 04976 Bile secretion
[list]

Species hsa(Human) mmu(Mouse) rno(Rat) mcc(Monkey) cfa(Dog) fca(Domestic cat)
UMAP
Representative coexpressed gene network LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
hsa04976 Bile secretion 36
hsa05207 Chemical carcinogenesis - receptor activation 15
hsa00830 Retinol metabolism 15
hsa05204 Chemical carcinogenesis - DNA adducts 15
hsa00980 Metabolism of xenobiotics by cytochrome P450 15
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mmu04976 Bile secretion 56
mmu00140 Steroid hormone biosynthesis 22
mmu05204 Chemical carcinogenesis - DNA adducts 22
mmu00830 Retinol metabolism 21
mmu05207 Chemical carcinogenesis - receptor activation 18
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno04976 Bile secretion 47
rno00140 Steroid hormone biosynthesis 15
rno00980 Metabolism of xenobiotics by cytochrome P450 15
rno05204 Chemical carcinogenesis - DNA adducts 15
rno00830 Retinol metabolism 14
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc04976 Bile secretion 38
mcc05204 Chemical carcinogenesis - DNA adducts 14
mcc05207 Chemical carcinogenesis - receptor activation 14
mcc00830 Retinol metabolism 13
mcc00980 Metabolism of xenobiotics by cytochrome P450 13
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa04976 Bile secretion 14
cfa04925 Aldosterone synthesis and secretion 8
cfa04970 Salivary secretion 7
cfa04971 Gastric acid secretion 7
cfa04024 cAMP signaling pathway 6
LCNkegg
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
fca04976 Bile secretion 25
fca04911 Insulin secretion 6
fca04918 Thyroid hormone synthesis 6
fca04925 Aldosterone synthesis and secretion 6
fca05207 Chemical carcinogenesis - receptor activation 6
Gene list in the network
Symbol Function*
ADCY2 adenylate cyclase 2
ADCY3 adenylate cyclase 3
AFM afamin
APOA4 apolipoprotein A4
AQP8 aquaporin 8
APOH apolipoprotein H
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
ATP1A2 ATPase Na+/K+ transporting subunit alpha 2
ATP1A3 ATPase Na+/K+ transporting subunit alpha 3
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
ATP1B3 ATPase Na+/K+ transporting subunit beta 3
BAAT bile acid-CoA:amino acid N-acyltransferase
SCARB1 scavenger receptor class B member 1
CYP3A7 cytochrome P450 family 3 subfamily A member 7
CYP2B6 cytochrome P450 family 2 subfamily B member 6
CYP3A4 cytochrome P450 family 3 subfamily A member 4
CYP3A5 cytochrome P450 family 3 subfamily A member 5
CYP4A11 cytochrome P450 family 4 subfamily A member 11
DHCR7 7-dehydrocholesterol reductase
F9 coagulation factor IX
F13B coagulation factor XIII B chain
GJB1 gap junction protein beta 1
GUCA2B guanylate cyclase activator 2B
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
LDLR low density lipoprotein receptor
OTC ornithine transcarbamylase
ABCB1 ATP binding cassette subfamily B member 1
ABCB4 ATP binding cassette subfamily B member 4
SLC10A1 solute carrier family 10 member 1
SLC22A1 solute carrier family 22 member 1
SULT2A1 sulfotransferase family 2A member 1
UGT2B4 UDP glucuronosyltransferase family 2 member B4
UGT2B7 UDP glucuronosyltransferase family 2 member B7
UGT2B10 UDP glucuronosyltransferase family 2 member B10
UGT2B15 UDP glucuronosyltransferase family 2 member B15
UGT2B17 UDP glucuronosyltransferase family 2 member B17
LRP8 LDL receptor related protein 8
SLC4A4 solute carrier family 4 member 4
SLCO1B1 solute carrier organic anion transporter family member 1B1
SLC22A7 solute carrier family 22 member 7
UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus
SLC27A5 solute carrier family 27 member 5
SLCO1B3 solute carrier organic anion transporter family member 1B3
A1CF APOBEC1 complementation factor
UGT1A10 UDP glucuronosyltransferase family 1 member A10
UGT1A9 UDP glucuronosyltransferase family 1 member A9
UGT1A4 UDP glucuronosyltransferase family 1 member A4
UGT1A1 UDP glucuronosyltransferase family 1 member A1
ABCG8 ATP binding cassette subfamily G member 8
ALDH8A1 aldehyde dehydrogenase 8 family member A1
UGT2A3 UDP glucuronosyltransferase family 2 member A3
FRMPD3 FERM and PDZ domain containing 3
SLC51B solute carrier family 51 subunit beta
KLB klotho beta
LOC101927136 uncharacterized LOC101927136
Symbol Function*
Adcy8 adenylate cyclase 8
Aox1 aldehyde oxidase 1
Aqp4 aquaporin 4
Aqp8 aquaporin 8
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide
Baat bile acid-Coenzyme A: amino acid N-acyltransferase
Cftr cystic fibrosis transmembrane conductance regulator
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38
Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39
Cyp51 cytochrome P450, family 51
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1
Ephx1 epoxide hydrolase 1, microsomal
Gata4 GATA binding protein 4
Hao1 hydroxyacid oxidase 1, liver
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
Ldlr low density lipoprotein receptor
Lipg lipase, endothelial
Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Masp2 mannan-binding lectin serine peptidase 2
Nr1i2 nuclear receptor subfamily 1, group I, member 2
Otc ornithine transcarbamylase
Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Slc22a8 solute carrier family 22 (organic anion transporter), member 8
Nr1h4 nuclear receptor subfamily 1, group H, member 4
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1
Slc10a2 solute carrier family 10, member 2
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5
Nr0b2 nuclear receptor subfamily 0, group B, member 2
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5
Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6
Abcg5 ATP binding cassette subfamily G member 5
Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
Slco1a1 solute carrier organic anion transporter family, member 1a1
Slco1a4 solute carrier organic anion transporter family, member 1a4
Slco1b2 solute carrier organic anion transporter family, member 1b2
Slco1a6 solute carrier organic anion transporter family, member 1a6
Cfhr1 complement factor H-related 1
Slc4a4 solute carrier family 4 (anion exchanger), member 4
Slc13a1 solute carrier family 13 (sodium/sulfate symporters), member 1
Tdo2 tryptophan 2,3-dioxygenase
Slc6a14 solute carrier family 6 (neurotransmitter transporter), member 14
Aqp9 aquaporin 9
Msmo1 methylsterol monoxygenase 1
Abcg8 ATP binding cassette subfamily G member 8
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1
Anks4b ankyrin repeat and sterile alpha motif domain containing 4B
Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3
Sult2a8 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
Akr1c6 aldo-keto reductase family 1, member C6
Ugt1a6a UDP glucuronosyltransferase 1 family, polypeptide A6A
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
Ugt2b38 UDP glucuronosyltransferase 2 family, polypeptide B38
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34
Adcy3 adenylate cyclase 3
Slc9a3 solute carrier family 9 (sodium/hydrogen exchanger), member 3
Slc51a solute carrier family 51, alpha subunit
Slco1a5 solute carrier organic anion transporter family, member 1a5
Slc22a7 solute carrier family 22 (organic anion transporter), member 7
Ugt2b37 UDP glucuronosyltransferase 2 family, polypeptide B37
Mlc1 megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
Acnat2 acyl-coenzyme A amino acid N-acyltransferase 2
Slc5a8 solute carrier family 5 (iodide transporter), member 8
Cyp2c70 cytochrome P450, family 2, subfamily c, polypeptide 70
Acnat1 acyl-coenzyme A amino acid N-acyltransferase 1
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36
Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
Acsm2 acyl-CoA synthetase medium-chain family member 2
Rundc3b RUN domain containing 3B
Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35
Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13
Nat8l N-acetyltransferase 8-like
Xkr9 X-linked Kx blood group related 9
Ces3a carboxylesterase 3A
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C
Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5
Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9
Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B
Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1
Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54
Cyp2c67 cytochrome P450, family 2, subfamily c, polypeptide 67
9130409I23Rik RIKEN cDNA 9130409I23 gene
Symbol Function*
Amy1a amylase, alpha 1A
Atp1a1 ATPase Na+/K+ transporting subunit alpha 1
Atp1a2 ATPase Na+/K+ transporting subunit alpha 2
Atp1b2 ATPase Na+/K+ transporting subunit beta 2
Mbl1 mannose binding lectin 1
Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B
Pygm glycogen phosphorylase, muscle associated
Slc10a1 solute carrier family 10 member 1
Slc9a3 solute carrier family 9 member A3
Ugt1a1 UDP glucuronosyltransferase family 1 member A1
Ugt2b UDP glycosyltransferase 2 family, polypeptide B
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1
Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
Sult2a1 sulfotransferase family 2A member 1
Slc12a1 solute carrier family 12 member 1
Abcc2 ATP binding cassette subfamily C member 2
Cyp7a1 cytochrome P450 family 7 subfamily A member 1
Atp1b1 ATPase Na+/K+ transporting subunit beta 1
Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
Mep1b meprin A subunit beta
Aqp8 aquaporin 8
Sqle squalene epoxidase
Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37
Baat bile acid CoA:amino acid N-acyltransferase
Slco1a1 solute carrier organic anion transporter family, member 1a1
Slco1b2 solute carrier organic anion transporter family member 1B2
Ugt2a1 UDP glucuronosyltransferase family 2 member A1
Sult1b1 sulfotransferase family 1B member 1
Nr1i3 nuclear receptor subfamily 1, group I, member 3
Slc27a5 solute carrier family 27 member 5
Slco1a3 solute carrier organic anion transporter family member 1A3
Slco1a5 solute carrier organic anion transporter family, member 1A5
Hnmt histamine N-methyltransferase
Ppargc1a PPARG coactivator 1 alpha
Abcb11 ATP binding cassette subfamily B member 11
Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35
Slc4a4 solute carrier family 4 member 4
Slco1a6 solute carrier organic anion transporter family, member 1a6
Slc22a7 solute carrier family 22 member 7
Abcg5 ATP binding cassette subfamily G member 5
Abcc3 ATP binding cassette subfamily C member 3
Msmo1 methylsterol monooxygenase 1
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C
Abcg8 ATP binding cassette subfamily G member 8
Slco1a4 solute carrier organic anion transporter family, member 1a4
Abcb1a ATP binding cassette subfamily B member 1A
Akr1d1 aldo-keto reductase family 1, member D1
Ces2e carboxylesterase 2E
Ugt2b15 UDP glucuronosyltransferase family 2 member B15
Slc17a3 solute carrier family 17 member 3
Ugt2b17 UDP glucuronosyltransferase family 2 member B17
Gpr39 G protein-coupled receptor 39
Ugt2a3 UDP glucuronosyltransferase family 2 member A3
Slc4a5 solute carrier family 4 member 5
Slc22a22 solute carrier family 22 (organic cation transporter), member 22
Ldlr low density lipoprotein receptor
Slc51b solute carrier family 51 subunit beta
Mroh2a maestro heat-like repeat family member 2A
Ugt2b10 UDP glucuronosyltransferase 2 family, polypeptide B10
Abcg2 ATP binding cassette subfamily G member 2
Slc7a13 solute carrier family 7 member 13
Acnat2 acyl-coenzyme A amino acid N-acyltransferase 2
Mfrp membrane frizzled-related protein
Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
Slc22a12 solute carrier family 22 member 12
Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2
Gltpd2 glycolipid transfer protein domain containing 2
Akr1c12l1 aldo-keto reductase family 1, member C12-like 1
RGD1559459 similar to Expressed sequence AI788959
Ugt1a5 UDP glucuronosyltransferase family 1 member A5
Acnat1 acyl-coenzyme A amino acid N-acyltransferase 1
LOC100361907 complement factor H-related protein B
LOC100364155 UDP-glucuronosyltransferase 2B2-like
LOC120093077 cytochrome P450 2C6
Symbol Function*
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
ABCB1 ATP binding cassette subfamily B member 1
CA2 carbonic anhydrase 2
LDLR low density lipoprotein receptor
ABCG2 ATP binding cassette subfamily G member 2
CFTR CF transmembrane conductance regulator
SLCO1B3 solute carrier organic anion transporter family member 1B3
UGT2B9*2 UDP Glucuronosyltransferase 2 family, polypeptide B9*2
CYP3A4 cytochrome P450 3A64
CYP2C8 cytochrome P450 family 2 subfamily C member 8
CYP1A1 cytochrome P450 family 1 subfamily A member 1
LOC694289 guanine nucleotide-binding protein G(s) subunit alpha
ANGPTL3 angiopoietin like 3
LOC695543 cocaine esterase
F9 coagulation factor IX
NR1H4 nuclear receptor subfamily 1 group H member 4
SLC16A12 solute carrier family 16 member 12
HNF4G hepatocyte nuclear factor 4 gamma
OTC ornithine transcarbamylase
ART4 ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
SLC5A12 solute carrier family 5 member 12
SLC10A2 solute carrier family 10 member 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1
MBL2 mannose binding lectin 2
SLC22A1 solute carrier family 22 member 1
AQP4 aquaporin 4
PLG plasminogen
SLCO1A2 solute carrier organic anion transporter family member 1A2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
ABCC3 ATP binding cassette subfamily C member 3
ABCB4 ATP binding cassette subfamily B member 4
MASP1 MBL associated serine protease 1
SLC51B solute carrier family 51 subunit beta
MTTP microsomal triglyceride transfer protein
SPINK1 serine peptidase inhibitor Kazal type 1
UGT2B7 UDP glucuronosyltransferase family 2 member B7
LOC709132 UDP-glucuronosyltransferase 2B30
LOC709234 UDP-glucuronosyltransferase 2B19
ABCB11 ATP binding cassette subfamily B member 11
UGT2A3 UDP glucuronosyltransferase family 2 member A3
NR5A2 nuclear receptor subfamily 5 group A member 2
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
LOC710412 UDP-glucuronosyltransferase 2B20
TINAG tubulointerstitial nephritis antigen
FAM83B family with sequence similarity 83 member B
TM4SF4 transmembrane 4 L six family member 4
NKAIN2 sodium/potassium transporting ATPase interacting 2
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2
ABCG8 ATP binding cassette subfamily G member 8
AOC1 amine oxidase copper containing 1
PAQR9 progestin and adipoQ receptor family member 9
CDCP1 CUB domain containing protein 1
GBA3 glucosylceramidase beta 3
C8A complement C8 alpha chain
SLC5A1 solute carrier family 5 member 1
SULT2A1 sulfotransferase family 2A member 1
LOC718141 UDP-glucuronosyltransferase 1-9
SPP2 secreted phosphoprotein 2
HAO1 hydroxyacid oxidase 1
SLC22A8 solute carrier family 22 member 8
PRKACA protein kinase cAMP-activated catalytic subunit alpha
APLP2 amyloid beta precursor like protein 2
CCL16 C-C motif chemokine ligand 16
ATP1A2 ATPase Na+/K+ transporting subunit alpha 2
CTDNEP1 CTD nuclear envelope phosphatase 1
LOC100427327 UDP-glucuronosyltransferase 2B23
BAAT bile acid-CoA:amino acid N-acyltransferase
LOC106992770 UDP-glucuronosyltransferase 1-8 pseudogene
CFHR5 complement factor H related 5
CFHR2 complement factor H related 2
AQP1 aquaporin 1
LOC114670009 uncharacterized LOC114670009
LOC114671445 UDP-glucuronosyltransferase 1-8-like
Symbol Function*
PRKACA protein kinase cAMP-activated catalytic subunit alpha
ABCB1 ATP binding cassette subfamily B member 1
GNAS GNAS complex locus
ATP1B1 ATPase Na+/K+ transporting subunit beta 1
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
SLC4A2 solute carrier family 4 member 2
SLC22A8 solute carrier family 22 member 8
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
ATP1B4 ATPase Na+/K+ transporting family member beta 4
ABCB4 ATP binding cassette subfamily B member 4
TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
FKBP8 FKBP prolyl isomerase 8
SCARB1 scavenger receptor class B member 1
ATP1B2 ATPase Na+/K+ transporting subunit beta 2
ACLY ATP citrate lyase
SQLE squalene epoxidase
AQP8 aquaporin 8
LDLR low density lipoprotein receptor
IDI1 isopentenyl-diphosphate delta isomerase 1
NEFL neurofilament light chain
LOC119870853 ferritin heavy chain-like
Symbol Function*
SLC2A1 solute carrier family 2 member 1
SLC10A1 solute carrier family 10 member 1
LSS lanosterol synthase
AQP4 aquaporin 4
NCEH1 neutral cholesterol ester hydrolase 1
RARG retinoic acid receptor gamma
SLC10A2 solute carrier family 10 member 2
ATP1A1 ATPase Na+/K+ transporting subunit alpha 1
SCARB1 scavenger receptor class B member 1
TNS1 tensin 1
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8
ABCB11 ATP binding cassette subfamily B member 11
RXRA retinoid X receptor alpha
ABCC2 ATP binding cassette subfamily C member 2
TTR transthyretin
SLC27A5 solute carrier family 27 member 5
LOC101087059 UDP-glucuronosyltransferase 2A1
SLCO1A2 solute carrier organic anion transporter family member 1A2
LOC101087662 UDP-glucuronosyltransferase 2A1-like
SLCO1B3 solute carrier organic anion transporter family member 1B3
LOC101088955 solute carrier family 22 member 8
DMGDH dimethylglycine dehydrogenase
ADCY6 adenylate cyclase 6
TMPRSS6 transmembrane serine protease 6
HNF4A hepatocyte nuclear factor 4 alpha
ABCG5 ATP binding cassette subfamily G member 5
PRKACB protein kinase cAMP-activated catalytic subunit beta
SLC17A3 solute carrier family 17 member 3
NXPE3 neurexophilin and PC-esterase domain family member 3
LOC101096785 sodium/potassium-transporting ATPase subunit alpha-2
NR1H4 nuclear receptor subfamily 1 group H member 4
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
SLC51A solute carrier family 51 subunit alpha
CYP7A1 cytochrome P450 family 7 subfamily A member 1
ADCY5 adenylate cyclase 5


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