[][] cfa  PDGFB Gene
functional annotation
Function   platelet derived growth factor subunit B
GO BP
GO:0003104 [list] [network] positive regulation of glomerular filtration  (1 genes)  ISS  
GO:0010512 [list] [network] negative regulation of phosphatidylinositol biosynthetic process  (1 genes)  ISS  
GO:0035793 [list] [network] positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway  (1 genes)  ISS  
GO:0038001 [list] [network] paracrine signaling  (1 genes)  ISS  
GO:0071506 [list] [network] cellular response to mycophenolic acid  (1 genes)  ISS  
GO:0072126 [list] [network] positive regulation of glomerular mesangial cell proliferation  (1 genes)  ISS  
GO:0072255 [list] [network] metanephric glomerular mesangial cell development  (1 genes)  ISS  
GO:0090280 [list] [network] positive regulation of calcium ion import  (1 genes)  ISS  
GO:1900127 [list] [network] positive regulation of hyaluronan biosynthetic process  (1 genes)  ISS  
GO:2000591 [list] [network] positive regulation of metanephric mesenchymal cell migration  (1 genes)  ISS  
GO:0001892 [list] [network] embryonic placenta development  (2 genes)  ISS  
GO:0002548 [list] [network] monocyte chemotaxis  (2 genes)  ISS  
GO:0010544 [list] [network] negative regulation of platelet activation  (2 genes)  ISS  
GO:0014911 [list] [network] positive regulation of smooth muscle cell migration  (2 genes)  ISS  
GO:0031954 [list] [network] positive regulation of protein autophosphorylation  (2 genes)  ISS  
GO:0032148 [list] [network] activation of protein kinase B activity  (2 genes)  ISS  
GO:0045737 [list] [network] positive regulation of cyclin-dependent protein serine/threonine kinase activity  (2 genes)  ISS  
GO:0045840 [list] [network] positive regulation of mitotic nuclear division  (2 genes)  ISS  
GO:0061098 [list] [network] positive regulation of protein tyrosine kinase activity  (2 genes)  ISS  
GO:0043536 [list] [network] positive regulation of blood vessel endothelial cell migration  (3 genes)  ISS  
GO:0043552 [list] [network] positive regulation of phosphatidylinositol 3-kinase activity  (3 genes)  ISS  
GO:0048008 [list] [network] platelet-derived growth factor receptor signaling pathway  (3 genes)  ISS  
GO:0048146 [list] [network] positive regulation of fibroblast proliferation  (3 genes)  ISS  
GO:1904707 [list] [network] positive regulation of vascular associated smooth muscle cell proliferation  (3 genes)  ISS  
GO:2000573 [list] [network] positive regulation of DNA biosynthetic process  (3 genes)  ISS  
GO:0018105 [list] [network] peptidyl-serine phosphorylation  (4 genes)  ISS  
GO:0001938 [list] [network] positive regulation of endothelial cell proliferation  (5 genes)  ISS  
GO:0032147 [list] [network] activation of protein kinase activity  (5 genes)  ISS  
GO:0048661 [list] [network] positive regulation of smooth muscle cell proliferation  (5 genes)  ISS  
GO:2000379 [list] [network] positive regulation of reactive oxygen species metabolic process  (5 genes)  ISS  
GO:0043406 [list] [network] positive regulation of MAP kinase activity  (6 genes)  ISS  
GO:0014068 [list] [network] positive regulation of phosphatidylinositol 3-kinase signaling  (7 genes)  ISS  
GO:0072593 [list] [network] reactive oxygen species metabolic process  (7 genes)  ISS  
GO:0050921 [list] [network] positive regulation of chemotaxis  (11 genes)  ISS  
GO:0018108 [list] [network] peptidyl-tyrosine phosphorylation  (12 genes)  ISS  
GO:0051781 [list] [network] positive regulation of cell division  (12 genes)  IEA  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (12 genes)  ISS  
GO:0060326 [list] [network] cell chemotaxis  (13 genes)  ISS  
GO:0007507 [list] [network] heart development  (17 genes)  ISS  
GO:0009611 [list] [network] response to wounding  (22 genes)  ISS  
GO:0043410 [list] [network] positive regulation of MAPK cascade  (22 genes)  ISS  
GO:0006468 [list] [network] protein phosphorylation  (24 genes)  ISS  
GO:0030097 [list] [network] hemopoiesis  (26 genes)  ISS  
GO:0045892 [list] [network] negative regulation of transcription, DNA-templated  (33 genes)  ISS  
GO:0045893 [list] [network] positive regulation of transcription, DNA-templated  (48 genes)  ISS  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (56 genes)  ISS  
GO CC
GO:0016323 [list] [network] basolateral plasma membrane  (11 genes)  ISS  
GO:0009986 [list] [network] cell surface  (33 genes)  ISS  
GO:0005737 [list] [network] cytoplasm  (390 genes)  ISS  
GO MF
GO:0016176 [list] [network] superoxide-generating NADPH oxidase activator activity  (1 genes)  ISS  
GO:0005161 [list] [network] platelet-derived growth factor receptor binding  (2 genes)  ISS  
GO:0008083 [list] [network] growth factor activity  (20 genes)  ISS  
GO:0042803 [list] [network] protein homodimerization activity  (25 genes)  ISS  
KEGG cfa01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (84 genes)
cfa04010 [list] [network] MAPK signaling pathway (288 genes)
cfa04014 [list] [network] Ras signaling pathway (229 genes)
cfa04015 [list] [network] Rap1 signaling pathway (213 genes)
cfa04020 [list] [network] Calcium signaling pathway (239 genes)
cfa04072 [list] [network] Phospholipase D signaling pathway (150 genes)
cfa04151 [list] [network] PI3K-Akt signaling pathway (359 genes)
cfa04510 [list] [network] Focal adhesion (201 genes)
cfa04540 [list] [network] Gap junction (88 genes)
cfa04630 [list] [network] JAK-STAT signaling pathway (156 genes)
cfa04810 [list] [network] Regulation of actin cytoskeleton (229 genes)
cfa05167 [list] [network] Kaposi sarcoma-associated herpesvirus infection (187 genes)
cfa05200 [list] [network] Pathways in cancer (537 genes)
cfa05206 [list] [network] MicroRNAs in cancer (276 genes)
cfa05211 [list] [network] Renal cell carcinoma (71 genes)
cfa05214 [list] [network] Glioma (74 genes)
cfa05215 [list] [network] Prostate cancer (99 genes)
cfa05218 [list] [network] Melanoma (73 genes)
cfa05231 [list] [network] Choline metabolism in cancer (96 genes)
cfa05418 [list] [network] Fluid shear stress and atherosclerosis (140 genes)
Protein NP_001003383.1  XP_038534694.1  XP_038534695.1  XP_038534696.1  XP_038534697.1 
BLAST NP_001003383.1  XP_038534694.1  XP_038534695.1  XP_038534696.1  XP_038534697.1 
Orthologous [Ortholog page] PDGFA (hsa)PDGFB (hsa)Pdgfa (mmu)Pdgfb (mmu)Pdgfb (rno)Pdgfa (rno)Pvf1 (dme)PDGFB (gga)PDGFA (gga)pdgfaa (dre)PDGFA (cfa)PDGFB (mcc)PDGFA (mcc)pdgfab (dre)pdgfbb (dre)si:ch211-79m20.1 (dre)PDGFB (fca)PDGFA (fca)
Subcellular
localization
wolf
extr 9,  E.R. 1  (predict for NP_001003383.1)
nucl 7,  cyto_nucl 4,  extr 3  (predict for XP_038534694.1)
extr 8,  E.R. 1,  E.R._golg 1  (predict for XP_038534695.1)
extr 9,  E.R. 1  (predict for XP_038534696.1)
extr 9,  E.R. 0,  E.R._golg 0  (predict for XP_038534697.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
cfa05200 Pathways in cancer 5
cfa05165 Human papillomavirus infection 4
cfa03320 PPAR signaling pathway 2
cfa04152 AMPK signaling pathway 2
cfa05417 Lipid and atherosclerosis 2
Genes directly connected with PDGFB on the network
coex z* Locus Function* Coexpression
detail
Entrez Gene ID*
4.7 NRARP NOTCH regulated ankyrin repeat protein [detail] 100683070
4.0 PRSS22 serine protease 22 [detail] 490056
3.9 FOXS1 forkhead box S1 [detail] 100684507
Coexpressed
gene list
[Coexpressed gene list for PDGFB]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 442986    
Refseq ID (protein) NP_001003383.1 
XP_038534694.1 
XP_038534695.1 
XP_038534696.1 
XP_038534697.1 


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