[←][→] rno  Gnas Gene
functional annotation
Function   GNAS complex locus  
GO BP
GO:0040032 [list] [network] post-embryonic body morphogenesis  (1 genes)  ISO  
GO:2000828 [list] [network] regulation of parathyroid hormone secretion  (3 genes)  ISO  
GO:0060789 [list] [network] hair follicle placode formation  (5 genes)  ISO  
GO:0035814 [list] [network] negative regulation of renal sodium excretion  (9 genes)  IMP  
GO:0007191 [list] [network] adenylate cyclase-activating dopamine receptor signaling pathway  (10 genes)  IBA IDA ISO  
GO:0040015 [list] [network] negative regulation of multicellular organism growth  (16 genes)  ISO  
GO:0071380 [list] [network] cellular response to prostaglandin E stimulus  (18 genes)  IDA  
GO:0071880 [list] [network] adenylate cyclase-activating adrenergic receptor signaling pathway  (20 genes)  ISO ISS  
GO:0071107 [list] [network] response to parathyroid hormone  (22 genes)  IEA ISO  
GO:0071514 [list] [network] genetic imprinting  (25 genes)  ISO  
GO:0043950 [list] [network] positive regulation of cAMP-mediated signaling  (29 genes)  ISO ISS  
GO:0045672 [list] [network] positive regulation of osteoclast differentiation  (32 genes)  ISO  
GO:0001958 [list] [network] endochondral ossification  (34 genes)  ISO  
GO:0035116 [list] [network] embryonic hindlimb morphogenesis  (35 genes)  ISO  
GO:0010765 [list] [network] positive regulation of sodium ion transport  (40 genes)  IMP  
GO:0070527 [list] [network] platelet aggregation  (48 genes)  ISO  
GO:0006306 [list] [network] DNA methylation  (49 genes)  ISO  
GO:0048701 [list] [network] embryonic cranial skeleton morphogenesis  (51 genes)  ISO  
GO:0006112 [list] [network] energy reserve metabolic process  (58 genes)  ISO  
GO:0045776 [list] [network] negative regulation of blood pressure  (67 genes)  IMP  
GO:0045669 [list] [network] positive regulation of osteoblast differentiation  (73 genes)  ISO  
GO:0120162 [list] [network] positive regulation of cold-induced thermogenesis  (99 genes)  ISO ISS  
GO:0071870 [list] [network] cellular response to catecholamine stimulus  (105 genes)  IDA  
GO:0035264 [list] [network] multicellular organism growth  (122 genes)  ISO  
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway  (132 genes)  IDA IMP ISO  
GO:0009791 [list] [network] post-embryonic development  (136 genes)  ISO  
GO:0051216 [list] [network] cartilage development  (175 genes)  ISO  
GO:0007188 [list] [network] adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (210 genes)  IBA  
GO:0060348 [list] [network] bone development  (230 genes)  ISO  
GO:0043588 [list] [network] skin development  (236 genes)  ISO  
GO:0001894 [list] [network] tissue homeostasis  (237 genes)  ISO  
GO:0043547 [list] [network] positive regulation of GTPase activity  (237 genes)  ISO ISS  
GO:0050890 [list] [network] cognition  (375 genes)  ISO  
GO:0048589 [list] [network] developmental growth  (489 genes)  ISO  
GO:0055074 [list] [network] calcium ion homeostasis  (497 genes)  IMP  
GO:0001501 [list] [network] skeletal system development  (513 genes)  ISO  
GO:0042493 [list] [network] response to drug  (643 genes)  ISO  
GO:0001934 [list] [network] positive regulation of protein phosphorylation  (760 genes)  IMP  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (1044 genes)  IDA  
GO:0007606 [list] [network] sensory perception of chemical stimulus  (1402 genes)  IBA  
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway  (2147 genes)  IEA IMP  
GO:0006357 [list] [network] regulation of transcription by RNA polymerase II  (2210 genes)  IMP  
GO:0009966 [list] [network] regulation of signal transduction  (2873 genes)  ISO  
GO CC
GO:0030142 [list] [network] COPI-coated Golgi to ER transport vesicle  (2 genes)  IDA  
GO:0005834 [list] [network] heterotrimeric G-protein complex  (34 genes)  IBA IDA  
GO:0032588 [list] [network] trans-Golgi network membrane  (37 genes)  ISO  
GO:0001726 [list] [network] ruffle  (174 genes)  IDA  
GO:0055037 [list] [network] recycling endosome  (174 genes)  IDA  
GO:0042383 [list] [network] sarcolemma  (175 genes)  IDA  
GO:0008021 [list] [network] synaptic vesicle  (259 genes)  IEA  
GO:0016324 [list] [network] apical plasma membrane  (397 genes)  IEA  
GO:0045121 [list] [network] membrane raft  (407 genes)  IDA  
GO:0043025 [list] [network] neuronal cell body  (756 genes)  IDA  
GO:0048471 [list] [network] perinuclear region of cytoplasm  (760 genes)  IDA ISO  
GO:0030425 [list] [network] dendrite  (800 genes)  ISO  
GO:0005768 [list] [network] endosome  (855 genes)  IDA  
GO:0005794 [list] [network] Golgi apparatus  (1405 genes)  IDA  
GO:0005576 [list] [network] extracellular region  (2120 genes)  IEA  
GO:0005829 [list] [network] cytosol  (3690 genes)  IDA ISO  
GO:0005886 [list] [network] plasma membrane  (5814 genes)  IDA TAS  
GO:0031224 [list] [network] intrinsic component of membrane  (6405 genes)  ISO  
GO:0005634 [list] [network] nucleus  (6599 genes)  ISO  
GO:0016020 [list] [network] membrane  (9382 genes)  IDA ISO  
GO:0005737 [list] [network] cytoplasm  (10463 genes)  IDA ISO  
GO MF
GO:0031852 [list] [network] mu-type opioid receptor binding  (4 genes)  IBA IDA IPI  
GO:0051430 [list] [network] corticotropin-releasing hormone receptor 1 binding  (4 genes)  IBA IPI  
GO:0010856 [list] [network] adenylate cyclase activator activity  (5 genes)  IDA ISS  
GO:0031698 [list] [network] beta-2 adrenergic receptor binding  (10 genes)  IBA IPI  
GO:0005159 [list] [network] insulin-like growth factor receptor binding  (14 genes)  IBA IPI  
GO:0031748 [list] [network] D1 dopamine receptor binding  (14 genes)  IBA IPI  
GO:0031681 [list] [network] G-protein beta-subunit binding  (22 genes)  IDA  
GO:0031683 [list] [network] G-protein beta/gamma-subunit complex binding  (25 genes)  IBA IEA  
GO:0035255 [list] [network] ionotropic glutamate receptor binding  (39 genes)  IBA IPI  
GO:0001965 [list] [network] G-protein alpha-subunit binding  (41 genes)  IPI  
GO:0043014 [list] [network] alpha-tubulin binding  (42 genes)  IDA  
GO:0003924 [list] [network] GTPase activity  (279 genes)  IBA IEA  
GO:0001664 [list] [network] G protein-coupled receptor binding  (307 genes)  IBA  
GO:0005525 [list] [network] GTP binding  (353 genes)  IDA IEA TAS  
GO:0019904 [list] [network] protein domain specific binding  (807 genes)  IPI  
GO:0046872 [list] [network] metal ion binding  (3303 genes)  IEA  
GO:0005515 [list] [network] protein binding  (7349 genes)  IPI  
KEGG rno01522 [list] [network] Endocrine resistance (94 genes)
rno04015 [list] [network] Rap1 signaling pathway (213 genes)
rno04020 [list] [network] Calcium signaling pathway (238 genes)
rno04024 [list] [network] cAMP signaling pathway (217 genes)
rno04072 [list] [network] Phospholipase D signaling pathway (150 genes)
rno04261 [list] [network] Adrenergic signaling in cardiomyocytes (148 genes)
rno04270 [list] [network] Vascular smooth muscle contraction (139 genes)
rno04540 [list] [network] Gap junction (87 genes)
rno04611 [list] [network] Platelet activation (126 genes)
rno04713 [list] [network] Circadian entrainment (98 genes)
rno04714 [list] [network] Thermogenesis (237 genes)
rno04724 [list] [network] Glutamatergic synapse (114 genes)
rno04726 [list] [network] Serotonergic synapse (123 genes)
rno04728 [list] [network] Dopaminergic synapse (132 genes)
rno04730 [list] [network] Long-term depression (61 genes)
rno04750 [list] [network] Inflammatory mediator regulation of TRP channels (115 genes)
rno04911 [list] [network] Insulin secretion (85 genes)
rno04912 [list] [network] GnRH signaling pathway (90 genes)
rno04913 [list] [network] Ovarian steroidogenesis (58 genes)
rno04915 [list] [network] Estrogen signaling pathway (135 genes)
rno04916 [list] [network] Melanogenesis (99 genes)
rno04918 [list] [network] Thyroid hormone synthesis (73 genes)
rno04921 [list] [network] Oxytocin signaling pathway (155 genes)
rno04922 [list] [network] Glucagon signaling pathway (104 genes)
rno04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes)
rno04924 [list] [network] Renin secretion (72 genes)
rno04925 [list] [network] Aldosterone synthesis and secretion (96 genes)
rno04926 [list] [network] Relaxin signaling pathway (128 genes)
rno04927 [list] [network] Cortisol synthesis and secretion (68 genes)
rno04928 [list] [network] Parathyroid hormone synthesis, secretion and action (105 genes)
rno04934 [list] [network] Cushing syndrome (158 genes)
rno04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes)
rno04961 [list] [network] Endocrine and other factor-regulated calcium reabsorption (59 genes)
rno04962 [list] [network] Vasopressin-regulated water reabsorption (44 genes)
rno04970 [list] [network] Salivary secretion (81 genes)
rno04971 [list] [network] Gastric acid secretion (75 genes)
rno04972 [list] [network] Pancreatic secretion (105 genes)
rno04976 [list] [network] Bile secretion (94 genes)
rno05012 [list] [network] Parkinson disease (270 genes)
rno05030 [list] [network] Cocaine addiction (47 genes)
rno05031 [list] [network] Amphetamine addiction (68 genes)
rno05032 [list] [network] Morphine addiction (92 genes)
rno05034 [list] [network] Alcoholism (177 genes)
rno05142 [list] [network] Chagas disease (104 genes)
rno05146 [list] [network] Amoebiasis (96 genes)
rno05163 [list] [network] Human cytomegalovirus infection (248 genes)
rno05165 [list] [network] Human papillomavirus infection (353 genes)
rno05200 [list] [network] Pathways in cancer (538 genes)
rno05207 [list] [network] Chemical carcinogenesis - receptor activation (228 genes)
rno05414 [list] [network] Dilated cardiomyopathy (94 genes)
Protein NP_001019994.4  NP_001153125.1  NP_001153128.1  NP_001346796.1  NP_062005.1  NP_068617.6  XP_038960221.1  XP_038960222.1  XP_038960223.1  XP_038960224.1  XP_038960225.1  XP_038960226.1  XP_038960227.1  XP_038960228.1  XP_038960229.1  XP_038960230.1  XP_038960231.1  XP_038960232.1  XP_038960233.1  XP_038960234.1  XP_038960235.1  XP_038960237.1  XP_038960238.1  XP_038960239.1 
BLAST NP_001019994.4  NP_001153125.1  NP_001153128.1  NP_001346796.1  NP_062005.1  NP_068617.6  XP_038960221.1  XP_038960222.1  XP_038960223.1  XP_038960224.1  XP_038960225.1  XP_038960226.1  XP_038960227.1  XP_038960228.1  XP_038960229.1  XP_038960230.1  XP_038960231.1  XP_038960232.1  XP_038960233.1  XP_038960234.1  XP_038960235.1  XP_038960237.1  XP_038960238.1  XP_038960239.1 
Orthologous [Ortholog page] GNAL (hsa)  GNAS (hsa)  Gnal (mmu)  Gnas (mmu)  Gnal (rno)  Galphas (dme)  gsa-1 (cel)  GNAS (cfa)  gnal2 (dre)  GNAS (gga)  GNAL (gga)  gnal (dre)  gnas (dre)  GNAL (cfa)  LOC694289 (mcc)  GNAL (fca)  LOC101098453 (fca)  GNAL (mcc) 
Subcellular
localization
wolf
nucl 8,  mito 2  (predict for NP_001019994.4)
mito 5,  nucl 3,  cyto_nucl 3,  E.R._mito 3,  mito_pero 3  (predict for NP_001153125.1)
mito 5,  nucl 3,  cyto_nucl 3,  E.R._mito 3,  mito_pero 3  (predict for NP_001153128.1)
cyto 4,  cyto_nucl 4,  mito 3,  nucl 2  (predict for NP_001346796.1)
cyto 4,  pero 2,  mito_pero 2,  plas 1,  extr_plas 1,  nucl 1,  extr 1  (predict for NP_062005.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  nucl 2,  mito 2,  mito_pero 1,  plas 1  (predict for NP_068617.6)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  mito 2,  nucl 2,  mito_pero 2,  plas 1  (predict for XP_038960221.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  nucl 2,  mito 2,  mito_pero 1,  plas 1  (predict for XP_038960222.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  nucl 2,  mito 2,  mito_pero 1,  plas 1  (predict for XP_038960223.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  mito 2,  nucl 2,  mito_pero 2,  plas 1  (predict for XP_038960224.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  mito 2,  nucl 2,  mito_pero 2,  plas 1  (predict for XP_038960225.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  nucl 2,  mito 2,  mito_pero 1,  plas 1  (predict for XP_038960226.1)
cyto 4,  cyto_mito 3,  cyto_nucl 3,  nucl 2,  mito 2,  mito_pero 1,  plas 1  (predict for XP_038960227.1)
nucl 7,  cyto_nucl 5,  cyto 3  (predict for XP_038960228.1)
nucl 6,  cyto_nucl 5,  cyto 3  (predict for XP_038960229.1)
cyto 4,  nucl 2,  mito 2,  mito_pero 1,  plas 1,  extr_plas 1,  pero 1,  golg 1  (predict for XP_038960230.1)
cyto 4,  pero 2,  mito_pero 2,  plas 1,  extr_plas 1,  nucl 1,  extr 1  (predict for XP_038960231.1)
cyto 4,  pero 2,  mito_pero 2,  plas 1,  extr_plas 1,  nucl 1,  extr 1  (predict for XP_038960232.1)
E.R. 3,  E.R._mito 3,  cyto 2,  extr 2,  cyto_nucl 2,  mito 1,  mito_pero 1,  E.R._golg 1  (predict for XP_038960233.1)
E.R._mito 2,  cyto 2,  E.R. 2,  extr 2,  mito 1,  cyto_plas 1,  mito_pero 1  (predict for XP_038960234.1)
E.R._mito 2,  E.R. 2,  extr 2,  cyto 2,  mito 2,  mito_pero 2,  nucl 1,  extr_plas 1,  cyto_plas 1  (predict for XP_038960235.1)
cyto 4,  nucl 2,  mito 2,  mito_pero 1,  plas 1,  extr_plas 1,  pero 1,  golg 1  (predict for XP_038960237.1)
cyto 5,  mito 2,  plas 1,  nucl 1,  golg 1  (predict for XP_038960238.1)
mito 5,  nucl 3,  cyto_nucl 3,  E.R._mito 3,  mito_pero 3  (predict for XP_038960239.1)
Gene coexpression
Network*for
coexpressed
genes
Coexpressed
gene list		 [Coexpressed gene list for Gnas]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 24896      
Refseq ID (protein) NP_001019994.4 
NP_001153125.1 
NP_001153128.1 
NP_001346796.1 
NP_062005.1 
NP_068617.6 
XP_038960221.1 
XP_038960222.1 
XP_038960223.1 
XP_038960224.1 
XP_038960225.1 
XP_038960226.1 
XP_038960227.1 
XP_038960228.1 
XP_038960229.1 
XP_038960230.1 
XP_038960231.1 
XP_038960232.1 
XP_038960233.1 
XP_038960234.1 
XP_038960235.1 
XP_038960237.1 
XP_038960238.1 
XP_038960239.1 


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