[←][→] rno  Gnai2 Gene
functional annotation
Function   G protein subunit alpha i2  
GO BP
GO:1903614 [list] [network] negative regulation of protein tyrosine phosphatase activity  (2 genes)  IMP  
GO:0140199 [list] [network] negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process  (3 genes)  IDA  
GO:0033864 [list] [network] positive regulation of NAD(P)H oxidase activity  (5 genes)  IMP  
GO:0001973 [list] [network] G protein-coupled adenosine receptor signaling pathway  (10 genes)  IBA IDA  
GO:0045955 [list] [network] negative regulation of calcium ion-dependent exocytosis  (11 genes)  IMP  
GO:0007213 [list] [network] G protein-coupled acetylcholine receptor signaling pathway  (14 genes)  ISO  
GO:0035815 [list] [network] positive regulation of renal sodium excretion  (15 genes)  IMP  
GO:0035810 [list] [network] positive regulation of urine volume  (16 genes)  IMP  
GO:0007216 [list] [network] G protein-coupled glutamate receptor signaling pathway  (17 genes)  IDA  
GO:0032930 [list] [network] positive regulation of superoxide anion generation  (25 genes)  IMP  
GO:0046628 [list] [network] positive regulation of insulin receptor signaling pathway  (26 genes)  IMP  
GO:0007214 [list] [network] gamma-aminobutyric acid signaling pathway  (29 genes)  IBA IDA  
GO:1904707 [list] [network] positive regulation of vascular associated smooth muscle cell proliferation  (38 genes)  IMP  
GO:2000179 [list] [network] positive regulation of neural precursor cell proliferation  (68 genes)  IMP  
GO:0007193 [list] [network] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway  (73 genes)  IBA ISO  
GO:0050805 [list] [network] negative regulation of synaptic transmission  (73 genes)  IDA  
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway  (132 genes)  IMP  
GO:0008016 [list] [network] regulation of heart contraction  (198 genes)  ISO  
GO:0007188 [list] [network] adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (210 genes)  IBA  
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade  (232 genes)  IMP  
GO:2001234 [list] [network] negative regulation of apoptotic signaling pathway  (243 genes)  IMP  
GO:0051924 [list] [network] regulation of calcium ion transport  (295 genes)  IDA  
GO:0051301 [list] [network] cell division  (366 genes)  ISO ISS  
GO:0008283 [list] [network] cell population proliferation  (578 genes)  ISO  
GO:0030335 [list] [network] positive regulation of cell migration  (586 genes)  IMP  
GO:0008284 [list] [network] positive regulation of cell population proliferation  (1044 genes)  IMP ISO  
GO:0007186 [list] [network] G protein-coupled receptor signaling pathway  (2147 genes)  IDA IEA  
GO CC
GO:0005834 [list] [network] heterotrimeric G-protein complex  (34 genes)  IBA  
GO:0030496 [list] [network] midbody  (179 genes)  ISO ISS  
GO:0070382 [list] [network] exocytic vesicle  (313 genes)  ISO  
GO:0045121 [list] [network] membrane raft  (407 genes)  IDA  
GO:0005813 [list] [network] centrosome  (614 genes)  ISO ISS  
GO:0030425 [list] [network] dendrite  (800 genes)  ISO  
GO:0044297 [list] [network] cell body  (850 genes)  ISO  
GO:0045202 [list] [network] synapse  (1547 genes)  IEA  
GO:0005654 [list] [network] nucleoplasm  (3378 genes)  IEA ISO  
GO:0005829 [list] [network] cytosol  (3690 genes)  IDA ISO  
GO:0005886 [list] [network] plasma membrane  (5814 genes)  IDA ISO TAS  
GO:0005634 [list] [network] nucleus  (6599 genes)  IDA  
GO:0016020 [list] [network] membrane  (9382 genes)  IDA  
GO:0005737 [list] [network] cytoplasm  (10463 genes)  ISO ISS  
GO MF
GO:0031683 [list] [network] G-protein beta/gamma-subunit complex binding  (25 genes)  IBA IEA  
GO:0003924 [list] [network] GTPase activity  (279 genes)  IBA IEA  
GO:0001664 [list] [network] G protein-coupled receptor binding  (307 genes)  IBA  
GO:0005525 [list] [network] GTP binding  (353 genes)  IEA  
GO:0019001 [list] [network] guanyl nucleotide binding  (379 genes)  IEA  
GO:0046872 [list] [network] metal ion binding  (3303 genes)  IEA  
GO:0005515 [list] [network] protein binding  (7349 genes)  IPI  
KEGG rno04015 [list] [network] Rap1 signaling pathway (213 genes)
rno04022 [list] [network] cGMP-PKG signaling pathway (171 genes)
rno04024 [list] [network] cAMP signaling pathway (217 genes)
rno04062 [list] [network] Chemokine signaling pathway (182 genes)
rno04071 [list] [network] Sphingolipid signaling pathway (124 genes)
rno04261 [list] [network] Adrenergic signaling in cardiomyocytes (148 genes)
rno04360 [list] [network] Axon guidance (181 genes)
rno04371 [list] [network] Apelin signaling pathway (137 genes)
rno04540 [list] [network] Gap junction (87 genes)
rno04611 [list] [network] Platelet activation (126 genes)
rno04670 [list] [network] Leukocyte transendothelial migration (117 genes)
rno04713 [list] [network] Circadian entrainment (98 genes)
rno04723 [list] [network] Retrograde endocannabinoid signaling (151 genes)
rno04724 [list] [network] Glutamatergic synapse (114 genes)
rno04725 [list] [network] Cholinergic synapse (113 genes)
rno04726 [list] [network] Serotonergic synapse (123 genes)
rno04727 [list] [network] GABAergic synapse (91 genes)
rno04728 [list] [network] Dopaminergic synapse (132 genes)
rno04730 [list] [network] Long-term depression (61 genes)
rno04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes)
rno04915 [list] [network] Estrogen signaling pathway (135 genes)
rno04916 [list] [network] Melanogenesis (99 genes)
rno04921 [list] [network] Oxytocin signaling pathway (155 genes)
rno04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes)
rno04924 [list] [network] Renin secretion (72 genes)
rno04926 [list] [network] Relaxin signaling pathway (128 genes)
rno04928 [list] [network] Parathyroid hormone synthesis, secretion and action (105 genes)
rno04934 [list] [network] Cushing syndrome (158 genes)
rno04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes)
rno04971 [list] [network] Gastric acid secretion (75 genes)
rno05012 [list] [network] Parkinson disease (270 genes)
rno05030 [list] [network] Cocaine addiction (47 genes)
rno05032 [list] [network] Morphine addiction (92 genes)
rno05034 [list] [network] Alcoholism (177 genes)
rno05133 [list] [network] Pertussis (73 genes)
rno05142 [list] [network] Chagas disease (104 genes)
rno05145 [list] [network] Toxoplasmosis (111 genes)
rno05163 [list] [network] Human cytomegalovirus infection (248 genes)
rno05170 [list] [network] Human immunodeficiency virus 1 infection (234 genes)
rno05200 [list] [network] Pathways in cancer (538 genes)
rno05207 [list] [network] Chemical carcinogenesis - receptor activation (228 genes)
Protein NP_112297.1  XP_006243920.1 
BLAST NP_112297.1  XP_006243920.1 
Orthologous [Ortholog page] GNA11 (hsa)  GNAI1 (hsa)  GNAI2 (hsa)  GNAI3 (hsa)  GNAO1 (hsa)  GNAQ (hsa)  GNAT1 (hsa)  GNAT2 (hsa)  GNAZ (hsa)  GNA14 (hsa)  Gna11 (mmu)  Gna14 (mmu)  Gnai1 (mmu)  Gnai2 (mmu)  Gnai3 (mmu)  Gnao1 (mmu)  Gnaq (mmu)  Gnat1 (mmu)  Gnat2 (mmu)  Gnaz (mmu)  Gnai3 (rno)  Gnai1 (rno)  Gnaz (rno)  Galphao (dme)  Galphaq (dme)  CG17760 (dme)  Galphai (dme)  Gnao1 (rno)  Gna11 (rno)  Gnaq (rno)  gnat1 (dre)  gnat2 (dre)  gpa-16 (cel)  egl-30 (cel)  goa-1 (cel)  gpa-15 (cel)  gpa-4 (cel)  gpa-7 (cel)  gpa-2 (cel)  gpa-3 (cel)  gpa-1 (cel)  gpa-8 (cel)  odr-3 (cel)  Gnat3 (mmu)  CG30054 (dme)  Gnat3 (rno)  Gna14 (rno)  gnaia (dre)  gnai2b (dre)  gnai2a (dre)  GNAT3 (hsa)  Gnat1 (rno)  Gnat2 (rno)  GNA11 (gga)  GNAI3 (gga)  gnao1a (dre)  gnao1b (dre)  gnai1 (dre)  GNAT2 (gga)  GNAT1 (gga)  GNAI2 (gga)  GNAI1 (gga)  GNAT1 (cfa)  GNA11 (cfa)  GNAQ (cfa)  GNAO1 (gga)  GNAQ (gga)  GNAT3 (gga)  GNA14 (gga)  GNAI2 (cfa)  gna15.1 (dre)  gna14 (dre)  GNAI1 (cfa)  GNA14 (cfa)  GNAT2 (cfa)  GNAT3 (cfa)  gna11b (dre)  gna14a (dre)  gna11a (dre)  gnaz (dre)  gnaq (dre)  gnav1 (dre)  GNAO1 (mcc)  GNAZ (cfa)  GNAO1 (cfa)  GNAI3 (cfa)  GNAI3 (mcc)  GNAT2 (mcc)  GNAI2 (mcc)  GNAT1 (mcc)  GNA14 (mcc)  GNAQ (mcc)  GNAZ (mcc)  GNAT3 (mcc)  GNAI1 (mcc)  GNA11 (mcc)  GNAZ (gga)  GPA1 (sce)  GPA2 (sce)  gnai3 (dre)  gna15.2 (dre)  GNA11 (fca)  GNAI2 (fca)  GNAT1 (fca)  GNAI1 (fca)  GNAT3 (fca)  GNA14 (fca)  GNAQ (fca)  GNAI3 (fca)  GNAT2 (fca)  GNAZ (fca)  GNAO1 (fca) 
Subcellular
localization
wolf
cyto 7,  mito_pero 1,  mito 1,  plas 1,  pero 1,  golg 1  (predict for NP_112297.1)
cyto 7,  mito_pero 1,  mito 1,  plas 1,  pero 1,  golg 1  (predict for XP_006243920.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
rno05132 Salmonella infection 5
rno05170 Human immunodeficiency virus 1 infection 4
rno05200 Pathways in cancer 4
rno04810 Regulation of actin cytoskeleton 4
rno04015 Rap1 signaling pathway 3
Genes directly connected with Gnai2 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
6.6 Cnpy3 canopy FGF signaling regulator 3 [detail] 685174
5.9 Myl12b myosin light chain 12B [detail] 50685
5.8 Arhgdia Rho GDP dissociation inhibitor alpha [detail] 360678
Coexpressed
gene list		 [Coexpressed gene list for Gnai2]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 81664      
Refseq ID (protein) NP_112297.1 
XP_006243920.1 


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