| functional annotation |
| Function |
adenylate cyclase 1 |
|
| GO BP |
|
GO:0150076 [list] [network] neuroinflammatory response
|
(10 genes)
|
IMP
|
 |
|
GO:0006171 [list] [network] cAMP biosynthetic process
|
(11 genes)
|
IBA
ISO
|
|
|
GO:0032793 [list] [network] positive regulation of CREB transcription factor activity
|
(18 genes)
|
IMP
|
|
|
GO:0007190 [list] [network] activation of adenylate cyclase activity
|
(23 genes)
|
TAS
|
|
|
GO:0009190 [list] [network] cyclic nucleotide biosynthetic process
|
(24 genes)
|
IEA
|
|
|
GO:1900273 [list] [network] positive regulation of long-term synaptic potentiation
|
(30 genes)
|
IMP
|
|
|
GO:0007616 [list] [network] long-term memory
|
(40 genes)
|
IGI
|
|
|
GO:2000300 [list] [network] regulation of synaptic vesicle exocytosis
|
(86 genes)
|
IMP
|
|
|
GO:0007189 [list] [network] adenylate cyclase-activating G protein-coupled receptor signaling pathway
|
(128 genes)
|
IBA
|
|
|
GO:0042752 [list] [network] regulation of circadian rhythm
|
(128 genes)
|
IMP
|
|
|
GO:0048511 [list] [network] rhythmic process
|
(264 genes)
|
IEA
|
|
|
GO:0007409 [list] [network] axonogenesis
|
(364 genes)
|
IMP
|
|
|
GO:0050804 [list] [network] modulation of chemical synaptic transmission
|
(663 genes)
|
IMP
|
|
|
GO:0035556 [list] [network] intracellular signal transduction
|
(1356 genes)
|
IEA
|
|
|
| GO CC |
|
GO:0098686 [list] [network] hippocampal mossy fiber to CA3 synapse
|
(50 genes)
|
IMP
|
|
|
GO:0099061 [list] [network] integral component of postsynaptic density membrane
|
(74 genes)
|
IDA
|
|
|
GO:0098685 [list] [network] Schaffer collateral - CA1 synapse
|
(115 genes)
|
IMP
|
|
|
GO:0014069 [list] [network] postsynaptic density
|
(401 genes)
|
IDA
|
|
|
GO:0098978 [list] [network] glutamatergic synapse
|
(518 genes)
|
IMP
|
|
|
GO:0005887 [list] [network] integral component of plasma membrane
|
(1555 genes)
|
IBA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(5442 genes)
|
ISO
TAS
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(5954 genes)
|
IEA
|
|
|
GO:0005634 [list] [network] nucleus
|
(7226 genes)
|
ISO
|
|
|
GO:0016020 [list] [network] membrane
|
(9571 genes)
|
IEA
|
|
|
GO:0005737 [list] [network] cytoplasm
|
(11434 genes)
|
IDA
|
|
|
| GO MF |
|
GO:0008294 [list] [network] calcium- and calmodulin-responsive adenylate cyclase activity
|
(5 genes)
|
ISO
|
|
|
GO:0004016 [list] [network] adenylate cyclase activity
|
(12 genes)
|
IBA
IGI
TAS
|
|
|
GO:0016849 [list] [network] phosphorus-oxygen lyase activity
|
(25 genes)
|
IEA
|
|
|
GO:0005516 [list] [network] calmodulin binding
|
(191 genes)
|
IEA
|
|
|
GO:0016829 [list] [network] lyase activity
|
(196 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1396 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2052 genes)
|
IEA
|
|
|
GO:0046872 [list] [network] metal ion binding
|
(3573 genes)
|
IEA
|
|
|
| KEGG |
mmu00230 [list] [network] Purine metabolism (133 genes) |
 |
| mmu01522 [list] [network] Endocrine resistance (93 genes) |
|
| mmu04015 [list] [network] Rap1 signaling pathway (214 genes) |
|
| mmu04020 [list] [network] Calcium signaling pathway (240 genes) |
|
| mmu04022 [list] [network] cGMP-PKG signaling pathway (173 genes) |
|
| mmu04024 [list] [network] cAMP signaling pathway (220 genes) |
|
| mmu04062 [list] [network] Chemokine signaling pathway (192 genes) |
|
| mmu04072 [list] [network] Phospholipase D signaling pathway (149 genes) |
|
| mmu04114 [list] [network] Oocyte meiosis (121 genes) |
|
| mmu04211 [list] [network] Longevity regulating pathway (90 genes) |
|
| mmu04213 [list] [network] Longevity regulating pathway - multiple species (62 genes) |
|
| mmu04261 [list] [network] Adrenergic signaling in cardiomyocytes (152 genes) |
|
| mmu04270 [list] [network] Vascular smooth muscle contraction (144 genes) |
|
| mmu04371 [list] [network] Apelin signaling pathway (137 genes) |
|
| mmu04540 [list] [network] Gap junction (86 genes) |
|
| mmu04611 [list] [network] Platelet activation (124 genes) |
|
| mmu04713 [list] [network] Circadian entrainment (98 genes) |
|
| mmu04714 [list] [network] Thermogenesis (231 genes) |
|
| mmu04720 [list] [network] Long-term potentiation (67 genes) |
|
| mmu04723 [list] [network] Retrograde endocannabinoid signaling (148 genes) |
|
| mmu04724 [list] [network] Glutamatergic synapse (113 genes) |
|
| mmu04725 [list] [network] Cholinergic synapse (112 genes) |
|
| mmu04727 [list] [network] GABAergic synapse (89 genes) |
|
| mmu04750 [list] [network] Inflammatory mediator regulation of TRP channels (127 genes) |
|
| mmu04911 [list] [network] Insulin secretion (86 genes) |
|
| mmu04912 [list] [network] GnRH signaling pathway (90 genes) |
|
| mmu04913 [list] [network] Ovarian steroidogenesis (63 genes) |
|
| mmu04914 [list] [network] Progesterone-mediated oocyte maturation (92 genes) |
|
| mmu04915 [list] [network] Estrogen signaling pathway (134 genes) |
|
| mmu04916 [list] [network] Melanogenesis (100 genes) |
|
| mmu04918 [list] [network] Thyroid hormone synthesis (74 genes) |
|
| mmu04921 [list] [network] Oxytocin signaling pathway (153 genes) |
|
| mmu04923 [list] [network] Regulation of lipolysis in adipocytes (56 genes) |
|
| mmu04925 [list] [network] Aldosterone synthesis and secretion (102 genes) |
|
| mmu04926 [list] [network] Relaxin signaling pathway (129 genes) |
|
| mmu04927 [list] [network] Cortisol synthesis and secretion (72 genes) |
|
| mmu04928 [list] [network] Parathyroid hormone synthesis, secretion and action (108 genes) |
|
| mmu04934 [list] [network] Cushing syndrome (162 genes) |
|
| mmu04935 [list] [network] Growth hormone synthesis, secretion and action (116 genes) |
|
| mmu04970 [list] [network] Salivary secretion (86 genes) |
|
| mmu04971 [list] [network] Gastric acid secretion (75 genes) |
|
| mmu04972 [list] [network] Pancreatic secretion (114 genes) |
|
| mmu04976 [list] [network] Bile secretion (100 genes) |
|
| mmu05032 [list] [network] Morphine addiction (91 genes) |
|
| mmu05142 [list] [network] Chagas disease (103 genes) |
|
| mmu05146 [list] [network] Amoebiasis (107 genes) |
|
| mmu05163 [list] [network] Human cytomegalovirus infection (256 genes) |
|
| mmu05166 [list] [network] Human T-cell leukemia virus 1 infection (250 genes) |
|
| mmu05200 [list] [network] Pathways in cancer (543 genes) |
|
| mmu05207 [list] [network] Chemical carcinogenesis - receptor activation (225 genes) |
|
| mmu05414 [list] [network] Dilated cardiomyopathy (94 genes) |
|
| Protein |
NP_033752.1
|
| BLAST |
NP_033752.1
|
| Orthologous |
[Ortholog page]
ADCY1 (hsa)
rut (dme)
Adcy1 (rno)
ADCY1 (gga)
adcy1a (dre)
adcy1b (dre)
ADCY1 (cfa)
ADCY1 (mcc)
erg28 (spo)
ADCY1 (fca)
|
Subcellular
localization
wolf |
|
plas 10
|
(predict for NP_033752.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| mmu04713 |
Circadian entrainment |
4 |
 |
| mmu04723 |
Retrograde endocannabinoid signaling |
4 |
 |
| mmu04024 |
cAMP signaling pathway |
4 |
 |
| mmu04724 |
Glutamatergic synapse |
3 |
 |
| mmu04921 |
Oxytocin signaling pathway |
3 |
 |
Genes directly connected with Adcy1 on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 5.6 |
Scn8a |
sodium channel, voltage-gated, type VIII, alpha |
[detail] |
0 |
20273 |
| 5.5 |
Sphkap |
SPHK1 interactor, AKAP domain containing |
[detail] |
0 |
77629 |
| 5.3 |
Ryr2 |
ryanodine receptor 2, cardiac |
[detail] |
0 |
20191 |
| 4.8 |
Ramp3 |
receptor (calcitonin) activity modifying protein 3 |
[detail] |
0 |
56089 |
| 4.4 |
Arhgap44 |
Rho GTPase activating protein 44 |
[detail] |
0 |
216831 |
|
Coexpressed
gene list |
[Coexpressed gene list for Adcy1]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
Adcy1 Gene
