| functional annotation |
| Function |
platelet-derived growth factor receptor, alpha polypeptide |
|
| GO BP |
|
GO:0003317 [list] [network] cardioblast cell midline fusion
|
(1 genes)
|
IMP
|
 |
|
GO:0003261 [list] [network] cardiac muscle progenitor cell migration to the midline involved in heart field formation
|
(3 genes)
|
IMP
|
|
|
GO:0048008 [list] [network] platelet-derived growth factor receptor signaling pathway
|
(7 genes)
|
IEA
|
|
|
GO:0060021 [list] [network] roof of mouth development
|
(13 genes)
|
IMP
|
|
|
GO:0061300 [list] [network] cerebellum vasculature development
|
(14 genes)
|
IGI
|
|
|
GO:0048702 [list] [network] embryonic neurocranium morphogenesis
|
(22 genes)
|
IGI
IMP
|
|
|
GO:1901532 [list] [network] regulation of hematopoietic progenitor cell differentiation
|
(34 genes)
|
IGI
|
|
|
GO:0001755 [list] [network] neural crest cell migration
|
(101 genes)
|
IGI
IMP
|
|
|
GO:0033674 [list] [network] positive regulation of kinase activity
|
(131 genes)
|
IBA
|
|
|
GO:0048701 [list] [network] embryonic cranial skeleton morphogenesis
|
(164 genes)
|
IBA
IMP
|
|
|
GO:0007169 [list] [network] transmembrane receptor protein tyrosine kinase signaling pathway
|
(249 genes)
|
IBA
IEA
|
|
|
GO:0006935 [list] [network] chemotaxis
|
(381 genes)
|
IEA
|
|
|
GO:0007507 [list] [network] heart development
|
(543 genes)
|
IMP
|
|
|
GO:0006468 [list] [network] protein phosphorylation
|
(744 genes)
|
IEA
|
|
|
GO:0016310 [list] [network] phosphorylation
|
(977 genes)
|
IEA
|
|
|
GO:0007275 [list] [network] multicellular organism development
|
(4070 genes)
|
IBA
IEA
|
|
|
| GO CC |
|
GO:0043235 [list] [network] receptor complex
|
(280 genes)
|
IBA
|
|
|
GO:0005929 [list] [network] cilium
|
(295 genes)
|
ISS
|
|
|
GO:0005794 [list] [network] Golgi apparatus
|
(732 genes)
|
IEA
ISS
|
|
|
GO:0042995 [list] [network] cell projection
|
(1027 genes)
|
IEA
|
|
|
GO:0005887 [list] [network] integral component of plasma membrane
|
(1125 genes)
|
IBA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(3451 genes)
|
IEA
|
|
|
GO:0016021 [list] [network] integral component of membrane
|
(6086 genes)
|
IEA
|
|
|
GO:0016020 [list] [network] membrane
|
(7959 genes)
|
IEA
|
|
|
| GO MF |
|
GO:0005018 [list] [network] platelet-derived growth factor alpha-receptor activity
|
(1 genes)
|
IBA
IEA
|
|
|
GO:0048407 [list] [network] platelet-derived growth factor binding
|
(1 genes)
|
IBA
|
|
|
GO:0004714 [list] [network] transmembrane receptor protein tyrosine kinase activity
|
(75 genes)
|
IBA
IEA
|
|
|
GO:0019838 [list] [network] growth factor binding
|
(80 genes)
|
IBA
|
|
|
GO:0004713 [list] [network] protein tyrosine kinase activity
|
(131 genes)
|
IEA
|
|
|
GO:0004672 [list] [network] protein kinase activity
|
(756 genes)
|
IEA
|
|
|
GO:0016301 [list] [network] kinase activity
|
(989 genes)
|
IEA
|
|
|
GO:0005524 [list] [network] ATP binding
|
(1578 genes)
|
IEA
|
|
|
GO:0000166 [list] [network] nucleotide binding
|
(2320 genes)
|
IEA
|
|
|
GO:0016740 [list] [network] transferase activity
|
(2575 genes)
|
IEA
|
|
|
| KEGG |
dre04010 [list] [network] MAPK signaling pathway (409 genes) |
 |
| dre04020 [list] [network] Calcium signaling pathway (377 genes) |
|
| dre04144 [list] [network] Endocytosis (341 genes) |
|
| dre04510 [list] [network] Focal adhesion (278 genes) |
|
| dre04540 [list] [network] Gap junction (132 genes) |
|
| dre04810 [list] [network] Regulation of actin cytoskeleton (308 genes) |
|
| Protein |
NP_571534.1
|
| BLAST |
NP_571534.1
|
| Orthologous |
[Ortholog page]
PDGFRA (hsa)
Pdgfra (mmu)
Pdgfra (rno)
PDGFRA (gga)
PDGFRA (cfa)
PDGFRA (mcc)
PDGFRA (fca)
|
Subcellular
localization
wolf |
|
cyto 5,
pero 2,
plas 1,
nucl 1,
extr 0,
mito 0,
E.R. 0,
lyso 0,
E.R._mito 0
|
(predict for NP_571534.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| dre04510 |
Focal adhesion |
3 |
 |
| dre04010 |
MAPK signaling pathway |
2 |
 |
| dre04020 |
Calcium signaling pathway |
2 |
 |
| dre04540 |
Gap junction |
2 |
 |
| dre04810 |
Regulation of actin cytoskeleton |
2 |
 |
Genes directly connected with pdgfra on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 6.7 |
reck |
reversion-inducing-cysteine-rich protein with kazal motifs |
[detail] |
100334698 |
| 5.7 |
colec12 |
collectin sub-family member 12 |
[detail] |
558942 |
| 5.5 |
fli1 |
Fli-1 proto-oncogene, ETS transcription factor |
[detail] |
30619 |
| 5.4 |
rarga |
retinoic acid receptor gamma a |
[detail] |
30606 |
| 5.4 |
bicc1a |
BicC family RNA binding protein 1a |
[detail] |
568201 |
| 5.2 |
adgra2 |
adhesion G protein-coupled receptor A2 |
[detail] |
560700 |
| 5.0 |
pdgfrb |
platelet-derived growth factor receptor, beta polypeptide |
[detail] |
559529 |
| 4.6 |
bmp16 |
bone morphogenetic protein 16 |
[detail] |
100329171 |
|
Coexpressed
gene list |
[Coexpressed gene list for pdgfra]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
pdgfra Gene
