[←][→] mcc  PLCB4 Gene
functional annotation
Function   phospholipase C beta 4  
GO BP
GO CC
GO MF
KEGG mcc00562 [list] [network] Inositol phosphate metabolism (76 genes)
mcc04015 [list] [network] Rap1 signaling pathway (229 genes)
mcc04020 [list] [network] Calcium signaling pathway (260 genes)
mcc04022 [list] [network] cGMP-PKG signaling pathway (169 genes)
mcc04062 [list] [network] Chemokine signaling pathway (200 genes)
mcc04070 [list] [network] Phosphatidylinositol signaling system (100 genes)
mcc04071 [list] [network] Sphingolipid signaling pathway (120 genes)
mcc04072 [list] [network] Phospholipase D signaling pathway (168 genes)
mcc04261 [list] [network] Adrenergic signaling in cardiomyocytes (153 genes)
mcc04270 [list] [network] Vascular smooth muscle contraction (142 genes)
mcc04310 [list] [network] Wnt signaling pathway (167 genes)
mcc04371 [list] [network] Apelin signaling pathway (142 genes)
mcc04540 [list] [network] Gap junction (94 genes)
mcc04611 [list] [network] Platelet activation (128 genes)
mcc04613 [list] [network] Neutrophil extracellular trap formation (214 genes)
mcc04621 [list] [network] NOD-like receptor signaling pathway (197 genes)
mcc04713 [list] [network] Circadian entrainment (103 genes)
mcc04720 [list] [network] Long-term potentiation (70 genes)
mcc04723 [list] [network] Retrograde endocannabinoid signaling (159 genes)
mcc04724 [list] [network] Glutamatergic synapse (115 genes)
mcc04725 [list] [network] Cholinergic synapse (114 genes)
mcc04726 [list] [network] Serotonergic synapse (118 genes)
mcc04728 [list] [network] Dopaminergic synapse (136 genes)
mcc04730 [list] [network] Long-term depression (61 genes)
mcc04742 [list] [network] Taste transduction (91 genes)
mcc04750 [list] [network] Inflammatory mediator regulation of TRP channels (101 genes)
mcc04911 [list] [network] Insulin secretion (88 genes)
mcc04912 [list] [network] GnRH signaling pathway (97 genes)
mcc04915 [list] [network] Estrogen signaling pathway (144 genes)
mcc04916 [list] [network] Melanogenesis (103 genes)
mcc04918 [list] [network] Thyroid hormone synthesis (76 genes)
mcc04919 [list] [network] Thyroid hormone signaling pathway (124 genes)
mcc04921 [list] [network] Oxytocin signaling pathway (163 genes)
mcc04922 [list] [network] Glucagon signaling pathway (115 genes)
mcc04924 [list] [network] Renin secretion (74 genes)
mcc04925 [list] [network] Aldosterone synthesis and secretion (104 genes)
mcc04926 [list] [network] Relaxin signaling pathway (133 genes)
mcc04927 [list] [network] Cortisol synthesis and secretion (69 genes)
mcc04928 [list] [network] Parathyroid hormone synthesis, secretion and action (109 genes)
mcc04929 [list] [network] GnRH secretion (64 genes)
mcc04933 [list] [network] AGE-RAGE signaling pathway in diabetic complications (102 genes)
mcc04934 [list] [network] Cushing syndrome (161 genes)
mcc04935 [list] [network] Growth hormone synthesis, secretion and action (128 genes)
mcc04961 [list] [network] Endocrine and other factor-regulated calcium reabsorption (54 genes)
mcc04970 [list] [network] Salivary secretion (88 genes)
mcc04971 [list] [network] Gastric acid secretion (80 genes)
mcc04972 [list] [network] Pancreatic secretion (110 genes)
mcc04973 [list] [network] Carbohydrate digestion and absorption (45 genes)
mcc05010 [list] [network] Alzheimer disease (441 genes)
mcc05016 [list] [network] Huntington disease (363 genes)
mcc05017 [list] [network] Spinocerebellar ataxia (155 genes)
mcc05022 [list] [network] Pathways of neurodegeneration - multiple diseases (540 genes)
mcc05142 [list] [network] Chagas disease (111 genes)
mcc05143 [list] [network] African trypanosomiasis (48 genes)
mcc05146 [list] [network] Amoebiasis (120 genes)
mcc05163 [list] [network] Human cytomegalovirus infection (257 genes)
mcc05200 [list] [network] Pathways in cancer (573 genes)
mcc05415 [list] [network] Diabetic cardiomyopathy (244 genes)
mcc05417 [list] [network] Lipid and atherosclerosis (237 genes)
Protein XP_015004953.1  XP_015004961.1  XP_015004962.1  XP_015004963.1  XP_028684021.1  XP_028684022.1  XP_028684023.1  XP_028684024.1  XP_028684025.1  XP_028684026.1  XP_028684027.1  XP_028684028.1  XP_028684029.1  XP_028684030.1  XP_028684031.1  XP_028684032.1  XP_028684033.1  XP_028684034.1 
BLAST XP_015004953.1  XP_015004961.1  XP_015004962.1  XP_015004963.1  XP_028684021.1  XP_028684022.1  XP_028684023.1  XP_028684024.1  XP_028684025.1  XP_028684026.1  XP_028684027.1  XP_028684028.1  XP_028684029.1  XP_028684030.1  XP_028684031.1  XP_028684032.1  XP_028684033.1  XP_028684034.1 
Orthologous [Ortholog page] PLCB2 (hsa)  PLCB3 (hsa)  PLCB4 (hsa)  PLCD1 (hsa)  Plcb1 (mmu)  Plcb2 (mmu)  Plcb3 (mmu)  Plcb4 (mmu)  Plcd1 (mmu)  Plcd4 (mmu)  PLCB1 (hsa)  Plcb1 (rno)  Plcd1 (rno)  Plcb4 (rno)  Plcb3 (rno)  norpA (dme)  Plc21C (dme)  Plcd3 (mmu)  PLCD4 (hsa)  Plcb2 (rno)  PLCZ1 (hsa)  PLCD3 (hsa)  Plcz1 (mmu)  Plcd4 (rno)  plc-4 (cel)  egl-8 (cel)  plc-2 (cel)  Plcd3 (rno)  plcd1b (dre)  plcb4 (dre)  PLCB4 (gga)  PLCZ1 (gga)  PLCD1 (gga)  PLCB2 (gga)  PLCD4 (gga)  PLCB1 (gga)  PLCD3 (gga)  PLCB3 (cfa)  PLCB4 (cfa)  PLCD4 (cfa)  PLCD1 (cfa)  PLCB1 (cfa)  PLCZ1 (cfa)  PLCD3 (cfa)  Plcz1 (rno)  plcd1a (dre)  plch2b (dre)  plcd4b (dre)  plcd3b (dre)  plcl1 (dre)  plcd4a (dre)  plcd3a (dre)  plcb2 (dre)  PLCD1 (mcc)  PLCD4 (mcc)  PLCB2 (mcc)  PLCZ1 (mcc)  PLCD3 (mcc)  PLCB3 (mcc)  PLCB1 (mcc)  PLC1 (sce)  plcb3 (dre)  LOC100149080 (dre)  LOC100537538 (dre)  PLCB2 (cfa)  PLCZ1 (fca)  PLCD3 (fca)  PLCD1 (fca)  PLCB4 (fca)  PLCD4 (fca)  PLCB2 (fca)  PLCB1 (fca)  PLCB3 (fca)  plcb1 (dre) 
Subcellular
localization
wolf
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_015004953.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_015004961.1)
cyto_nucl 4,  nucl 4,  cyto 4,  cysk 1  (predict for XP_015004962.1)
cyto 4,  nucl 4,  cysk 1  (predict for XP_015004963.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684021.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684022.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684023.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684024.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684025.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684026.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684027.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684028.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684029.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684030.1)
nucl 5,  cyto_nucl 4,  cyto 3,  cysk 1  (predict for XP_028684031.1)
cyto_nucl 4,  nucl 4,  cyto 4,  cysk 1  (predict for XP_028684032.1)
nucl 4,  cyto 4,  cysk 1  (predict for XP_028684033.1)
nucl 4,  cyto_nucl 4,  cyto 4,  cyto_plas 2,  cysk 1  (predict for XP_028684034.1)
Gene coexpression
Network*for
coexpressed
genes
LCNloc
[Cytoscape]
KEGG* ID Title #genes Link to the KEGG* map
(Multiple genes)
mcc05202 Transcriptional misregulation in cancer 2
mcc04022 cGMP-PKG signaling pathway 2
mcc04924 Renin secretion 2
mcc05022 Pathways of neurodegeneration - multiple diseases 2
Genes directly connected with PLCB4 on the network
coex z* Locus Function* Coexpression
detail		 Entrez Gene ID*
5.4 ZFPM2 zinc finger protein, FOG family member 2 [detail] 696568
4.0 MEIS1 Meis homeobox 1 [detail] 697685
4.0 TRMT9B tRNA methyltransferase 9B (putative) [detail] 706796
Coexpressed
gene list		 [Coexpressed gene list for PLCB4]
Gene expression
All samples [Expression pattern for all samples]
Tissue specificity*
Link to other DBs
Entrez Gene ID 718418      
Refseq ID (protein) XP_015004953.1 
XP_015004961.1 
XP_015004962.1 
XP_015004963.1 
XP_028684021.1 
XP_028684022.1 
XP_028684023.1 
XP_028684024.1 
XP_028684025.1 
XP_028684026.1 
XP_028684027.1 
XP_028684028.1 
XP_028684029.1 
XP_028684030.1 
XP_028684031.1 
XP_028684032.1 
XP_028684033.1 
XP_028684034.1 


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