| functional annotation |
| Function |
vinculin a |
|
| GO BP |
|
GO:0086013 [list] [network] membrane repolarization during cardiac muscle cell action potential
|
(4 genes)
|
IMP
|
 |
|
GO:0003181 [list] [network] atrioventricular valve morphogenesis
|
(15 genes)
|
IMP
|
|
|
GO:0045214 [list] [network] sarcomere organization
|
(39 genes)
|
IMP
|
|
|
GO:0060047 [list] [network] heart contraction
|
(100 genes)
|
IMP
|
|
|
GO:0007155 [list] [network] cell adhesion
|
(578 genes)
|
IEA
|
|
|
| GO CC |
|
GO:0042383 [list] [network] sarcolemma
|
(47 genes)
|
IEA
|
|
|
GO:0005912 [list] [network] adherens junction
|
(81 genes)
|
IDA
|
|
|
GO:0015629 [list] [network] actin cytoskeleton
|
(298 genes)
|
IEA
|
|
|
GO:0030054 [list] [network] cell junction
|
(875 genes)
|
IEA
|
|
|
GO:0005886 [list] [network] plasma membrane
|
(3451 genes)
|
IEA
|
|
|
GO:0005737 [list] [network] cytoplasm
|
(7473 genes)
|
IEA
|
|
|
GO:0016020 [list] [network] membrane
|
(7959 genes)
|
IEA
|
|
|
| GO MF |
|
GO:0051015 [list] [network] actin filament binding
|
(208 genes)
|
IEA
|
|
|
GO:0003779 [list] [network] actin binding
|
(404 genes)
|
IEA
|
|
|
GO:0005198 [list] [network] structural molecule activity
|
(518 genes)
|
IEA
|
|
|
| KEGG |
dre04510 [list] [network] Focal adhesion (278 genes) |
 |
| dre04520 [list] [network] Adherens junction (118 genes) |
|
| dre04810 [list] [network] Regulation of actin cytoskeleton (308 genes) |
|
| Protein |
NP_001122153.1
XP_005156897.1
XP_005156899.1
XP_021336251.1
|
| BLAST |
NP_001122153.1
XP_005156897.1
XP_005156899.1
XP_021336251.1
|
| Orthologous |
[Ortholog page]
VCL (hsa)
Vcl (mmu)
Vinc (dme)
deb-1 (cel)
Vcl (rno)
VCL (gga)
VCL (cfa)
VCL (mcc)
vclb (dre)
VCL (fca)
|
Subcellular
localization
wolf |
|
cyto 7,
cyto_nucl 4,
mito 1,
nucl 1
|
(predict for NP_001122153.1)
|
|
cyto 7,
cyto_nucl 4,
mito 1,
nucl 1
|
(predict for XP_005156897.1)
|
|
cyto 7,
cyto_nucl 4,
mito 2,
nucl 1,
E.R._mito 1,
mito_pero 1
|
(predict for XP_005156899.1)
|
|
cyto 7,
cyto_nucl 4,
mito 2,
extr 1,
nucl 1
|
(predict for XP_021336251.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| dre04010 |
MAPK signaling pathway |
2 |
 |
| dre04260 |
Cardiac muscle contraction |
2 |
 |
| dre04261 |
Adrenergic signaling in cardiomyocytes |
2 |
 |
Genes directly connected with vcla on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
Entrez Gene ID* |
| 6.7 |
cacna2d1a |
calcium channel, voltage-dependent, alpha 2/delta subunit 1a |
[detail] |
561434 |
| 6.3 |
usp13 |
ubiquitin specific peptidase 13 |
[detail] |
558011 |
| 6.1 |
jph1b |
junctophilin 1b |
[detail] |
556485 |
| 5.4 |
plekha7a |
pleckstrin homology domain containing, family A member 7a |
[detail] |
571486 |
| 5.3 |
myo18aa |
myosin XVIIIAa |
[detail] |
566880 |
| 4.9 |
mical2b |
microtubule associated monooxygenase, calponin and LIM domain containing 2b |
[detail] |
569564 |
| 4.7 |
uckl1b |
uridine-cytidine kinase 1-like 1b |
[detail] |
558466 |
| 4.7 |
cacnb1 |
calcium channel, voltage-dependent, beta 1 subunit |
[detail] |
436925 |
| 4.5 |
dgkaa |
diacylglycerol kinase, alpha a |
[detail] |
724010 |
| 4.4 |
lemd1 |
LEM domain containing 1 |
[detail] |
436879 |
|
Coexpressed
gene list |
[Coexpressed gene list for vcla]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
vcla Gene
