| functional annotation |
| Function |
platelet derived growth factor D |
|
| GO BP |
|
GO:0071673 [list] [network] positive regulation of smooth muscle cell chemotaxis
|
(3 genes)
|
IEA
|
 |
|
GO:2000439 [list] [network] positive regulation of monocyte extravasation
|
(3 genes)
|
IEA
|
|
|
GO:0072126 [list] [network] positive regulation of glomerular mesangial cell proliferation
|
(6 genes)
|
IEA
|
|
|
GO:0036120 [list] [network] cellular response to platelet-derived growth factor stimulus
|
(21 genes)
|
IEA
|
|
|
GO:0031954 [list] [network] positive regulation of protein autophosphorylation
|
(27 genes)
|
IBA
|
|
|
GO:0048008 [list] [network] platelet-derived growth factor receptor signaling pathway
|
(35 genes)
|
IBA
|
|
|
GO:0048146 [list] [network] positive regulation of fibroblast proliferation
|
(48 genes)
|
IEA
|
|
|
GO:0071230 [list] [network] cellular response to amino acid stimulus
|
(71 genes)
|
IEA
|
|
|
GO:0070301 [list] [network] cellular response to hydrogen peroxide
|
(75 genes)
|
IEA
|
|
|
GO:0051781 [list] [network] positive regulation of cell division
|
(88 genes)
|
IEA
|
|
|
GO:0043406 [list] [network] positive regulation of MAP kinase activity
|
(89 genes)
|
IBA
|
|
|
GO:0014068 [list] [network] positive regulation of phosphatidylinositol 3-kinase signaling
|
(91 genes)
|
IBA
|
|
|
GO:0048661 [list] [network] positive regulation of smooth muscle cell proliferation
|
(102 genes)
|
IEA
|
|
|
GO:0071560 [list] [network] cellular response to transforming growth factor beta stimulus
|
(161 genes)
|
IEA
|
|
|
GO:0070374 [list] [network] positive regulation of ERK1 and ERK2 cascade
|
(217 genes)
|
IBA
|
|
|
GO:0050730 [list] [network] regulation of peptidyl-tyrosine phosphorylation
|
(267 genes)
|
IEA
|
|
|
GO:0030335 [list] [network] positive regulation of cell migration
|
(554 genes)
|
IBA
|
|
|
GO:0008284 [list] [network] positive regulation of cell population proliferation
|
(976 genes)
|
IBA
|
|
|
GO:0007275 [list] [network] multicellular organism development
|
(4941 genes)
|
IEA
|
|
|
| GO CC |
|
GO:0005788 [list] [network] endoplasmic reticulum lumen
|
(313 genes)
|
TAS
|
|
|
GO:0000139 [list] [network] Golgi membrane
|
(626 genes)
|
TAS
|
|
|
GO:0005615 [list] [network] extracellular space
|
(3622 genes)
|
IBA
|
|
|
GO:0005576 [list] [network] extracellular region
|
(4632 genes)
|
TAS
|
|
|
| GO MF |
|
GO:0005161 [list] [network] platelet-derived growth factor receptor binding
|
(15 genes)
|
IBA
|
|
|
GO:0070851 [list] [network] growth factor receptor binding
|
(141 genes)
|
IBA
|
|
|
GO:0008083 [list] [network] growth factor activity
|
(162 genes)
|
IEA
|
|
|
| KEGG |
hsa01521 [list] [network] EGFR tyrosine kinase inhibitor resistance (79 genes) |
 |
| hsa04010 [list] [network] MAPK signaling pathway (294 genes) |
|
| hsa04014 [list] [network] Ras signaling pathway (232 genes) |
|
| hsa04015 [list] [network] Rap1 signaling pathway (210 genes) |
|
| hsa04020 [list] [network] Calcium signaling pathway (240 genes) |
|
| hsa04072 [list] [network] Phospholipase D signaling pathway (148 genes) |
|
| hsa04151 [list] [network] PI3K-Akt signaling pathway (354 genes) |
|
| hsa04510 [list] [network] Focal adhesion (201 genes) |
|
| hsa04540 [list] [network] Gap junction (88 genes) |
|
| hsa04810 [list] [network] Regulation of actin cytoskeleton (218 genes) |
|
| hsa05215 [list] [network] Prostate cancer (97 genes) |
|
| hsa05218 [list] [network] Melanoma (72 genes) |
|
| hsa05231 [list] [network] Choline metabolism in cancer (98 genes) |
|
| Protein |
NP_079484.1
NP_149126.1
|
| BLAST |
NP_079484.1
NP_149126.1
|
| Orthologous |
[Ortholog page]
Pdgfd (rno)
Pdgfd (mmu)
PDGFD (gga)
PDGFD (cfa)
PDGFD (mcc)
pdgfd (dre)
PDGFD (fca)
|
Subcellular
localization
wolf |
|
extr 6,
mito 2,
lyso 1,
E.R._mito 1
|
(predict for NP_079484.1)
|
|
extr 6,
mito 2,
lyso 2
|
(predict for NP_149126.1)
|
|
| Gene coexpression |
Network*for
coexpressed
genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map
(Multiple genes) |
| hsa04621 |
NOD-like receptor signaling pathway |
4 |
 |
| hsa05132 |
Salmonella infection |
3 |
 |
| hsa04613 |
Neutrophil extracellular trap formation |
2 |
 |
| hsa05130 |
Pathogenic Escherichia coli infection |
2 |
 |
| hsa05131 |
Shigellosis |
2 |
 |
Genes directly connected with PDGFD on the network
| coex z* |
Locus |
Function* |
Coexpression
detail |
CoexPub |
Entrez Gene ID* |
| 4.8 |
TGFBR3 |
transforming growth factor beta receptor 3 |
[detail] |
0 |
7049 |
| 4.5 |
CASP4LP |
caspase 4 like, pseudogene |
[detail] |
0 |
643733 |
| 4.5 |
ENPP5 |
ectonucleotide pyrophosphatase/phosphodiesterase family member 5 |
[detail] |
0 |
59084 |
|
Coexpressed
gene list |
[Coexpressed gene list for PDGFD]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|
PDGFD Gene
