| functional annotation |
| Function |
inositol 1,4,5-trisphosphate receptor, type 1a |
|
| GO BP |
|
GO:0070588 [list] [network] calcium ion transmembrane transport
|
(124 genes)
|
IEA
|
 |
|
GO:0006816 [list] [network] calcium ion transport
|
(146 genes)
|
IEA
|
 |
|
GO:0006811 [list] [network] ion transport
|
(915 genes)
|
IEA
|
 |
|
GO:0055085 [list] [network] transmembrane transport
|
(991 genes)
|
IEA
|
 |
|
GO:0006355 [list] [network] regulation of transcription, DNA-templated
|
(2255 genes)
|
IBA
|
 |
|
| GO CC |
|
GO:0005789 [list] [network] endoplasmic reticulum membrane
|
(569 genes)
|
IEA
|
 |
|
GO:0005783 [list] [network] endoplasmic reticulum
|
(906 genes)
|
IEA
|
 |
|
GO:0016021 [list] [network] integral component of membrane
|
(6086 genes)
|
IEA
|
 |
|
GO:0016020 [list] [network] membrane
|
(7959 genes)
|
IEA
|
 |
|
| GO MF |
|
GO:0005220 [list] [network] inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
|
(4 genes)
|
IEA
|
 |
|
GO:0070679 [list] [network] inositol 1,4,5 trisphosphate binding
|
(15 genes)
|
IEA
|
 |
|
GO:0005262 [list] [network] calcium channel activity
|
(105 genes)
|
IEA
|
 |
|
GO:0005216 [list] [network] ion channel activity
|
(438 genes)
|
IEA
|
 |
|
GO:0000978 [list] [network] RNA polymerase II cis-regulatory region sequence-specific DNA binding
|
(988 genes)
|
IBA
|
 |
|
GO:0000981 [list] [network] DNA-binding transcription factor activity, RNA polymerase II-specific
|
(1261 genes)
|
IBA
|
 |
|
| KEGG |
dre04020 [list] [network] Calcium signaling pathway (377 genes) |
 |
| dre04070 [list] [network] Phosphatidylinositol signaling system (118 genes) |
 |
| dre04114 [list] [network] Oocyte meiosis (151 genes) |
 |
| dre04140 [list] [network] Autophagy - animal (200 genes) |
 |
| dre04210 [list] [network] Apoptosis (201 genes) |
 |
| dre04218 [list] [network] Cellular senescence (200 genes) |
 |
| dre04270 [list] [network] Vascular smooth muscle contraction (177 genes) |
 |
| dre04371 [list] [network] Apelin signaling pathway (193 genes) |
 |
| dre04540 [list] [network] Gap junction (132 genes) |
 |
| dre04621 [list] [network] NOD-like receptor signaling pathway (173 genes) |
 |
| dre04625 [list] [network] C-type lectin receptor signaling pathway (129 genes) |
 |
| dre04912 [list] [network] GnRH signaling pathway (132 genes) |
 |
| Protein |
XP_005166152.1
XP_009300860.1
XP_009300862.1
XP_009300863.1
XP_017212153.1
XP_017212154.1
XP_017212155.1
XP_021330287.1
XP_021330288.1
XP_021330289.1
XP_021330290.1
XP_021330291.1
XP_021330292.1
XP_021330293.1
XP_021330294.1
XP_021330295.1
XP_021332899.1
|
| BLAST |
XP_005166152.1
XP_009300860.1
XP_009300862.1
XP_009300863.1
XP_017212153.1
XP_017212154.1
XP_017212155.1
XP_021330287.1
XP_021330288.1
XP_021330289.1
XP_021330290.1
XP_021330291.1
XP_021330292.1
XP_021330293.1
XP_021330294.1
XP_021330295.1
XP_021332899.1
|
| Orthologous |
[Ortholog page]
ITPR1 (hsa)
ITPR2 (hsa)
ITPR3 (hsa)
Itpr1 (mmu)
Itpr2 (mmu)
Itpr3 (mmu)
Itpr1 (rno)
Itpr3 (rno)
Itpr (dme)
Itpr2 (rno)
itr-1 (cel)
ITPR1 (gga)
ITPR2 (gga)
ITPR3 (gga)
ITPR1 (cfa)
ITPR3 (cfa)
ITPR2 (cfa)
itpr2 (dre)
ITPR1 (mcc)
ITPR2 (mcc)
ITPR3 (mcc)
itpr3 (dre)
itpr1b (dre)
ITPR3 (fca)
ITPR1 (fca)
ITPR2 (fca)
|
Subcellular localization wolf |
|
plas 8,
E.R. 2
|
(predict for XP_005166152.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_009300860.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_009300862.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_009300863.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_017212153.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_017212154.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_017212155.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330287.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330288.1)
|
|
plas 8,
E.R. 2
|
(predict for XP_021330289.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330290.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330291.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330292.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330293.1)
|
|
cyto 6,
cyto_nucl 4,
nucl 2,
pero 1
|
(predict for XP_021330294.1)
|
|
plas 7,
E.R. 2
|
(predict for XP_021330295.1)
|
|
nucl 3,
cyto_nucl 3,
pero 3,
cyto 2,
plas 1,
mito 1
|
(predict for XP_021332899.1)
|
|
| Gene coexpression |
Network*for coexpressed genes |
| KEGG* ID |
Title |
#genes |
Link to the KEGG* map (Multiple genes) |
| dre04020 |
Calcium signaling pathway |
3 |
|
| dre04210 |
Apoptosis |
2 |
|
| dre04070 |
Phosphatidylinositol signaling system |
2 |
|
Genes directly connected with itpr1a on the network
| coex z* |
Locus |
Function* |
Coexpression detail |
Entrez Gene ID* |
| 5.3 |
lrrk2 |
leucine-rich repeat kinase 2 |
[detail] |
559366 |
| 4.7 |
atp11c |
ATPase phospholipid transporting 11C |
[detail] |
368385 |
| 4.6 |
dennd2b |
DENN domain containing 2B |
[detail] |
323827 |
| 4.4 |
sh3tc1 |
SH3 domain and tetratricopeptide repeats 1 |
[detail] |
100535608 |
|
Coexpressed gene list |
[Coexpressed gene list for itpr1a]
|
| Gene expression |
| All samples |
[Expression pattern for all samples]
|
| Tissue specificity* |
|